• Title/Summary/Keyword: Profile effect

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THE EFFECT OF PDGF-BB AND IGF-I COMBINATION ON THE HEALING OF ARTIFICIAL PERIAPICAL LESIONS IN BEAGLE DOGS (PDGF-BB와 IGF-I 혼합 투여가 비글견 인공 치근단 병소의 치유에 미치는 영향에 관한 연구)

  • Kim, Mi-Ri;Kim, Min-Kyum;Yoon, Soo-Han
    • Restorative Dentistry and Endodontics
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    • v.25 no.1
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    • pp.1-16
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    • 2000
  • It is difficult to treat the endodontic apical perforation successfully. In this study, we hypothesized that the application of PDGF-BB and IGF-I into periapical perforation site may accelerate periapical healing and lead to bone deposition. And the specificity of osteonectin in periapical healing was investigated. The experiments were performed on the upper and lower 51 premolar teeth of 4 beagle dogs. The pulp chamber of each tooth was opened and the dental plaque was inserted into the canal for developing the periapical lesion for 5 weeks. Then, the roots were artificially perforated at the apex with the number 4 profile of .06 taper. In each step, standard periapical radiographs were taken to compare the size of lesion each other. The radiographs were scanned and analyzed by image analysis system. The mean and standard deviation of periradicular radiolucency ratios were calculated in each group. ANOVA was used for comparison. 51 premolars were grouped into 3 groups; control group, calcium hydroxide-treated group and calcium hydroxide plus growth factors-treated group. In the control group, the apical perforations were not sealed and obturated with gutta-percha and ZOE sealer by lateral condensation technique. In the experimental groups, the apical perforation were sealed with calcium hydroxide and with/without $4{\mu}g$ of PDGF-BB & IGF-I in cellulose gel and obturated by lateral condensation technique. Fluorescent bone markers were used to measure new bone formation. Following 2, 4, 12 weeks after experiment the dogs were sacrificed and histologic sections were prepared. Each tooth block including periapical lesion was sectioned mesiodistally. One half of the sections were decalcified with 6% nitric acid and processed by standard paraffin embedding technique. The sections were stained by hematoxylin and eosin, and immunostained for osteonectin. Histomorphometrical measurement of neoformed bone was performed using a light microscope. And the other half of the sections were prepared by undecalcified preparation, and confocal laser scanning microscopic investigations were done.

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Study of the ENC reduction considering Update (갱신을 고려한 전자해도 소형화 연구)

  • Shim, Woo-Seong;Park, Jae-Min;Suh, Sang-Hyun
    • Journal of Navigation and Port Research
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    • v.27 no.4
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    • pp.425-430
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    • 2003
  • The satellite navigation system is widely used for identifying a user's position regardless of weather or geographic conditions and also make effect on new technology of marine LBS(Location Based Service). which has the technology of geographic information such as the ENC. Generally, there are conceivable systems of marine LBS such as ECDIS, or ECS that use the ENC itself with powerful processor in installed type on ships bridge. Since the ENC is relatively heavy structure with dummy format for data transfer between different systems, we should reduce the ENC to small and compact size in order to use it in mobile platform. In this paper, we assumed that the mobile system like PDA, or Webpad can be used for small navigation or information system in marine field. We considered the reduction of the ENC size to make them fit well to small capability of mobile platform. However, the ENC should be updated periodically by update profile data produced by HO. If we would reduce the ENC without a consideration of update, we could not get newly updated data furthermore. As summary, we studied considerations for ENC reduction with update capability. It will make the ENC be useful in many low performance platforms for various applications.

산란계 육성기 계란급이가 초기 산란 특징에 미치는 영향

  • 김상호;장병귀;최철환;서옥석;이상진;류경선
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 2003.11a
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    • pp.97-98
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    • 2003
  • This experiment was conducted to investigate the effect of restricted feeding to pullet on growth and laying Performance, egg qualify and endocrine Profile in brown layers. 1,080 brown-layer chicks divided to three diet treatments, conventional diet and two restricted diets, for 70 weeks. Conventional diets(C) was formulated by NRC recommendation, and one of restricted diet started from seven to seventeen week of age(T1), and another started from twelve to seventeen(T2) with adjusted eighty percentage amount of conventional diet. Body weight decreased with starting restriction of feeding comparing to the C(P<0.05), but reached to similar weight in all treatments at twenty week regardless restriction. All of birds started to lay egg around 1,400 to 1,450gram of body weight though the age was in order of C, T2 and T1. Overall e99 Production was the highest in T1 (P<0.05) and there were not difference in C and T2. Average egg weight also showed similar to the tendency of egg production. Feed intake was higher in T1 during maximum production(P<0.05), but there were not difference in all treatments after the peak. Overall feed conversion ratio improved in T1 compared to C and T1(p<0.05). Restriction feeding in rearing period could be beneficial to improve egg productivity and to decrease feed cost.

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Numerical Analysis of Grout Flow and Injection Pressure Affected by Joint Roughness and Aperture (절리 거칠기와 간극 변화에 따른 그라우트 유동과 주입압에 관한 수치해석적 연구)

  • Jeon, Ki-Hwan;Ryu, Dong-Woo;Kim, Hyung-Mok;Park, Eui-Seob;Song, Jae-Jun
    • Tunnel and Underground Space
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    • v.20 no.2
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    • pp.82-91
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    • 2010
  • Grouting technology is one of the ground improvement methods used in water controlling and reinforcement of rock mass in underground structure construction. It is necessarily required to find out the characteristics of grout flow through discontinuities in a rock mass for an adequate grout design and performance assessment. Laminar flow is not always applicable in simulating a grout flow in a rock mass, since the rock joints usually have apertures at a micro-scale and the flow through these joints is affected by the joint roughness and the velocity profile of the flow changes partially near the roughness. Thus, the influence of joint roughness and aperture on the grout flow in rough rock joint was numerically investigated in this study. The commercial computational fluid dynamics code, FLUENT, was applied for this purpose. The computed results by embedded Herschel-Bulkley model and VOF (volume of fluid) model, which are applicable to simulate grout flow in a narrow rock joint that is filled with air and water, were well compared with that of analytical results and previously published laboratory test for the verification. The injection pressure required to keep constant injection rate of grout was calculated in a variety of Joint Roughness Coefficient (JRC) and aperture conditions, and the effect of joint roughness and aperture on grout flow were quantified.

Corn (Zea mays L.) Root Distribution in Response to Variation in Soil Water Content (토양 수분함량에 따른 옥수수 뿌리 분포의 변화)

  • Kim, Won-Il;Jung, Goo-Bok;Huck, M.G.;Kim, Yong-Woong;Park, Ro-Dong
    • Korean Journal of Soil Science and Fertilizer
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    • v.35 no.1
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    • pp.1-11
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    • 2002
  • Root distribution was monitored in the root zone of corn fields on several soil series in central Illinois during three growing seasons in order to find the effect of soil series and tillage system on root growth. A minirhizotron technique was used to videotape each soil profile in weekly intervals to a depth of 75 cm under conventional tillage (CT) and no tillage (NT) systems of cultivation. Root distribution near soil surface generally increased during the early stages of the growing season, but declined as surface soil moisture was depleted in late summer. Even though root distribution was not significantly different between soil series in this experiment. differences in root distribution between soil series were associated with the increases in root-available water storage capacity. Root population in the top 30 cm of NT plots. where increased water infiltration rates and saturated flow of soil moisture into the subsoil, was generally higher than that of CT plots in Illinois corn fields. Foots appeared in the deeper layers later in the growing season, with root penetration into subsoil layers occurring as much as 2-3 weeks earlier on the NT plots than in CT plots. In conclusion, root distribution was significantly affected by the tillage systems, but not different by soil series.

Effect of Non-Equilibrium Condensation on Force Coefficients in Transonic Airfoil Flow (천음속 에어포일 유동에서 비평형 응축이 Force Coefficients 에 미치는 영향)

  • Jeon, Heung Kyun;Choi, Seung Min;Kang, Hui Bo;Kwon, Young Doo;Kwon, Soon Bum
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.12
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    • pp.1009-1015
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    • 2014
  • The present study investigated the effects of non-equilibrium condensation with the angle of attack on the coefficients of pressure, lift, and drag in the transonic 2-D flow of NACA0012 by numerical analysis of the total variation diminishing (TVD) scheme. At $T_0=298k$ and ${\alpha}=3^{\circ}$, the lift coefficients for $M_{\infty}=0.78$ and 0.81 decreased monotonically with increasing ${\Phi}_0$. In contrast, for $M_{\infty}$ corresponding to the Mach number of the force break, $C_L$ increased with ${\Phi}_0$. For ${\alpha}=3^{\circ}$ and ${\Phi}_0=0%$, $C_D$ increased markedly as $M_{\infty}$ increased. However, at ${\Phi}_0=60%$ and ${\alpha}=3^{\circ}$, which corresponded to the case of the condensation having a large influence, $C_D$ increased slightly as $M_{\infty}$ increased. The decrease in profile drag by non-equilibrium condensation grew as the angle of attack and stagnation relative humidity increased for the same free stream transonic Mach number. At ${\Phi}_0=0%$, the coefficient of the wave drag increased with the attack angle and free stream Mach number. When ${\Phi}_0$ > 50%, the coefficient of the wave drag decreased as ${\alpha}$ and $M_{\infty}$ increased. Lowering ${\Phi}_0$ and increasing $M_{\infty}$ increased the maximum Mach number.

Tandem Mass Spectrometric Analysis for Disorders in Amino, Organic and Fatty Acid Metabolism : 2 Years of SCL Experience in Korea

  • Yoon, Hye-Ran;Lee, Kyung Ryul
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.3 no.1
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    • pp.86-93
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    • 2003
  • Background : The SCL began screening of newborns and high risk group blood spots with tandem mass spectrometry (MS/MS) in April 2001. Our goal was to determine approximate prevalence of metabolic disorders, optimization of decision criteria for estimation of preventive effect with early diagnosis. This report describes the ongoing effort to identify more than 30 metabolic disorders by MS/MS in South Korea. Methods : Blood spot was collected from day 2 to 30 (mostly from day 2 to 10) after birth for newborn. Blood spot of high risk group was from the pediatric patients in NICU, developmental delay, mental retardation, strong family history of metabolic disorders. One punch (3.2 mm ID) of dried blood spots was extracted with $150{\mu}L$ of methanol containing isotopically labelled amino acids (AA) and acylcarnitines (AC) internal standards. Butanolic HCl was added and incubated at $65^{\circ}C$ for 15 min. The butylated extract was introduced into the inlet of MS/MS. Neutral loss of m/z 102 and parent ion mode of m/z 85 were set for the analyses of AA and AC, respectively. Diagnosis was confirmed by repeating acylcarnitine profile, urine organic acid and plasma amino acid analysis, direct enzyme assay, or molecular testing. Results : Approximately 31,000 neonates and children were screened and the estimated prevalence (newborn/high risk group), sensitivity, specificity and recall rate amounted to 1:2384/1:2066, 96.55%, 99.98%, and 0.73%, respectively. Confirmed 28 (0.09%) multiple metabolic disorders (newborn/high risk) were as follows; 13 amino acid disorders [classical PKU (3/4), BH4 deficient-hyperphenylalaninemia (0/1), Citrullinemia (1/0), Homocystinuria (0/2), Hypermethioninemia (0/1), Tyrosinemia (1/0)], 8 organic acidurias [Propionic aciduria (2/1), Methylmalonic aciduria (0/1), Isovaleric aciduria (1/1), 3-methylcrotonylglycineuria (1/0), Glutaric aciduria type1 (1/0)], 7 fatty acid oxidation disorders [LCHAD def. (2/2), Mitochondrial TFP def. (0/1), VLCAD def. (1/0), LC3KT def. (0/1). Conclnsion : The relatively normal development of 10 patients with metabolic disorders among newborns (except for the expired) demonstrates the usefulness of newborn screening by MS/MS for early diagnosis and medical intervention. However, close coordination between the MS/MS screening laboratory and the metabolic clinic/biochmical geneticists is needed to determine proper decision of screening parameters, confirmation diagnosis, follow-up scheme and additional tests.

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Police Officers' Cognitions of Police Investigation Specialization (수사경과제에 대한 경찰공무원의 인식)

  • Choi, Mu-Chan
    • The Journal of the Korea Contents Association
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    • v.9 no.6
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    • pp.289-299
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    • 2009
  • This study set out to analyze the perceptions of investigative police officers and division police officers regarding Police Investigation Specialization, which had been in effect for four years, identify the problems, and search for alternative policies. The results led to the following alternative policies; first, the communication among the members should be facilitated by trading the jobs between investigative policemen and division members in certain percentage regularly, integrating job education and special work, and developing diverse support programs for detective activities to provide them with opportunities to experience and understand investigation. The second suggestion concerns the investigation members' morale. There should be a range of measures to boost their moral such as allocating separate budget and personnel to support the investigation department and the treatment of major criminal and civil cases, giving each investigation team an office and investigation room to improve their working environment, readjusting the promotion ratio of Police Investigation Specialization to introduce a promotion system proper for each investigation's characteristics. The third suggestion is to secure job efficiency. It's required to reinforce the current short-term specialized education program to bring up practical and professional investigators, open the certification exam of professional investigators to all members so that every policeman can have their abilities recognized and approved as long as they have the demanded capabilities, and create a system of shedding off the members idle at work by reflecting low performance records when evaluating the members to decide who to dismiss from Police Investigation Specialization. And finally, it's important to divide duties rationally. The rationality of duties division can be guaranteed by setting the guidelines for direct handling for the team leader to help him devote himself to his duties, defining objective criteria of measuring investigation workload, and creating devoted systems and teams for simple and small accidents so that experienced investigators can deal with high-profile cases.

MODIS-estimated Microphysical Properties of Clouds Developed in the Presence of Biomass Burning Aerosols (MODIS 관측자료를 이용한 러시아 산불 영향 하에 발달한 구름의 미세 물리적 특성 연구)

  • Kim, Shin-Young;Sohn, Byung-Ju
    • Korean Journal of Remote Sensing
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    • v.24 no.4
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    • pp.289-298
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    • 2008
  • An algorithm was developed to retrieve both cloud optical thickness and effective particle radius considered the aerosol effect on clouds. This study apply the algorithm of Nakajima and Nakajima (1995) that is used to retrieve cloud optical thickness and effective particle radius from visible, near infrared satellite spectral measurements. To retrieve cloud properties, Look-up table (LUT) was made under different atmospheric conditions by using a radiative transfer model. Especially the vertical distribution of aerosol is based on a tropospheric aerosol profile in radiative transfer model. In the case study, we selected the extensive forest fire occurred in Russia in May 2003. The aerosol released from this fire may be transported to Korea. Cloud properties obtained from these distinct atmospheric situations are analysed in terms of their possible changes due to the interactions of the clouds with the aerosol particle plumes. Cloud properties over the East sea at this time was retrieved using new algorithm. The algorithm is applied to measurements from the MODerate Resolution Imaging Spectrometer (MODIS) onboard the Terra spacecrafts. As a result, cloud effective particle radius was decreased and cloud optical thickness was increased during aerosol event. Specially, cloud effective particle radius is hardly greater than $20{\mu}m$ when aerosol particles were present over the East Sea. Clouds developing in the aerosol event tend to have more numerous but smaller droplets.

Effect of Heating system on Roof garden for Turf growth (옥상 잔디녹화시 Heating system의 효과)

  • Koh, Seuk-Koo;Shin, Hong-Kyun;Tae, Hyun-Sook;Kim, Yong-Seon;Ahn, Gil-Man
    • Asian Journal of Turfgrass Science
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    • v.23 no.2
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    • pp.279-286
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    • 2009
  • This study was carried out to utilize the waste heat from office building for turfgrass culture on a roof garden. Heating system had been installed in the middle of soil profile on the turf areas in the garden plots. The results showed that the installation of heating system increased the shoot density, turfgrass quality, coverage rate, and root length compared with the control plots. The surface temperature of heating plots reached at $10.9^{\circ}C$ when the control plot showed $0^{\circ}C$, however, the soil moisture content was decreased 1.9% by the heating system. When the height of the snow accumulation reached over a 15cm, the it took only 4 days to melt out completely, while the height did not changed those period at the control plots. When the water temperature in boiler increased to $60^{\circ}C$ from a proper temperature of $55^{\circ}C$ in turf growth, the desiccation from leaf tip was started to occur caused by drought stress. More detail research should be followed in stress physiology in turf management in roof garden operation.