• Journal of applied mathematics & informatics
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• v.6 no.2
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• pp.417-432
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• 1999

This paper describes a fuzzy system designed to support production planning in an industrial unit producing cardboard boxes. In this industrial unit orders for n boxes of width w, length l, height h, made of q layers of type k paper for delivery in t units of time are produced. In the production of such orders apart from meeting the orders specifications it is usually tried to minimize the margin trim loss the number of machine setups and the holding cost of the finished orders. Considering the dynamism of production systems that are influenced by such factors as market demand fluctuations changes in commercial priorities raw material availability and pro-ducation capabilities we solve this multi-objective problem by fuzzy set theory.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.27 no.1
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• pp.1-8
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• 2004

This study intend to make easy modification, even if there is a new job or structure change, by modularizing program and computerize and automation of production control management used in CIM. under the condition where manager control production on the job-site, for increasing connection with other operation and management on the computer by monitoring center computer, recognizing information by computer is needed, it is possible by converting transaction. So this study goal is to make delivery control and order control fast and accurate by finding dynamic history of machine and production information in enterprise without input production and quality information by themselves with quality information system. So production increase and quality improvement are possible by diminishing manager's and producer's work with the result of the study combining POP and CIM, after that, in e-business and m-business period that every enterprise must pass, customer satisfaction and sales promotion are possible with employee's computerizing minds. these study result also can knowledge process condition with theoretical class and have a power in finding a solution with foundation of theoretical knowledge.

• Journal of the Korea Safety Management & Science
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• v.14 no.1
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• pp.123-128
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• 2012

This paper deals with the productivity increment through construction of HT8 production system for automobile factory in China. HT8 production system start to build up several management indices. The important management indices consists of organization management, location management, management of order, management of defective item, management of delivery information, and warehouse management. This HT8 production system is expected to obtain the improvement for overall organization management and reduction by 50% in warehouse cost.

• International Journal of Naval Architecture and Ocean Engineering
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• v.3 no.3
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• pp.181-192
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• 2011

Recently, the speed of change related with enterprise management is getting faster than ever owing to the competition among companies, technique diffusion, shortening of product lifecycle, excessive supply of market. For the example, the compliance condition (such as delivery date, product quality, etc.) from the ship owner is getting complicated and the needs for the new product such as FPSO, FSRU are coming to fore. This paradigm shift emphasize the rapid response rather than the competitive price, flexibility and agility rather than effective and optimal perspective for the domestic shipbuilding company. So, domestic shipbuilding companies have to secure agile and flexible ship production environment that could respond change of market and requirements of customers in order to continue a competitive edge in the world market. In this paper, I'm going to define a standard shipbuilding production management system by investigating the environment of domestic major shipbuilding companies. Also, I'm going to propose a unified ship production management and system for the operation of unified management through detail analysis of the activities and the data flow of ship production management. And, the system functions for the strategic approach of ship production management are investigated through the business administration tools such as performance pyramid, VDT and BSC. Lastly, the research of applying strategic KPI to the digital shipyard as virtual execution platform is conducted.

• Asia-Pacific Journal of Business
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• v.13 no.3
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• pp.449-461
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• 2022

Purpose - The purpose of this study to explore factors consumers prioritize when purchasing seafood online. The originality of the study lies on adopting AHP-based approach in analyzing prioritized purchasing factors of seafood online. Design/methodology/approach - A survey was conducted targeting Korean consumers who have purchased seafood online. AHP method was applied to rank factors consumers prioritize before making decision. Findings - First, product's factor ranked first among other high level factors including delivery service, seller, online platform. Second, sanitation, taste, country of origin ranked first, second, third respectively, within product's factors. Third, safe delivery, timeliness, information accuracy ranked first, second, third respectively, within delivery factors. Fourth, consumer reviews, consumer response ability, promotion ranked first, second, third within seller factors. Fifth, Personal information management system, credibility, user-friendliness ranked first, second, third, within online platform factors. Research implications or Originality - To activate seafood online market, it is crucial to assure consumers that the seafood is well managed in a sanitary way from the production site to table. Existing government programs such as seafood traceability system, HACCP, and cold-chain infrastructure needs improvement. Due to highly perishable characteristic of seafood, delivery factors matter when purchasing online. Online platforms needs to continue to improve delivery service. Seafood products are mostly not branded and without objective information about their properties. Creating quality classification and seafood brands are likely to help consumers chose seafood online.

• Journal of Pharmaceutical Investigation
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• v.40 no.spc
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• pp.63-73
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• 2010

Solid lipid nanoparticles (SLNs) have emerged to combine the advantages of polymeric nanoparticles and lipid emulsions in early 1990s. SLNs can present several desirable properties derived from the solid state core. When formulating SLNs, there should be careful considerations about the physical state of the inner solid lipid core and its polymorphism and supercooling behavior. In this review, SLNs were compared to lipid emulsion and emulsion of supercooled melt to understand the unusual behaviors compared to lipid emulsions and to have insights into stability and release mechanism. SLNs have been regarded as biocompatible system because lipids are usually well-tolerable ingredients than polymers. Several studies showed good tolerability of SLNs in terms of cytotoxicity and hemolysis. Similar to various other nanoparticulate drug delivery systems, SLNs can also change biodistribution of the incorporated drugs in a way to enhance therapeutic effect. Most of all, large scale production of SLNs was extablished wihtout using organic solvents. Although there is no SLN product in the market till date, several advantagious properties of SLNs and the progress we have seen so far would make commercial product of SLNs possible before long and encourage research community to apply SLN-based formulations for water-insoluble drugs.

• Journal of the Korea Safety Management & Science
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• v.19 no.3
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• pp.109-115
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• 2017

In order to increase the productivity of the logistics center and transportation, we try to articulate the priority ranking factors of the productivity influenced by the personality of the field workers (logistics center workers) and functional workers (drivers) via the AHP technique Individual personality was studied by applying the Big 5 model of psychological factors (openness, Conscientiousness, extroversion, Agreeableness, neuroticism). In this paper, extraversion was critically analyzed as a priority factor. A trait of extroversion is a strongly active and individual personality. In this study, the field workers are logistics center workers and the functional workers are drivers. They are interactively influenced in the In & Out operation. For example, when it comes to 'up and down work' and 'inspection work', the functional workers perform 'up and down work' and 'delivery work' and the field workers perform 'inspection work'. Stressing on the respective work has an affect on work productivity. Inspection workforce has something to do with inventory management. Functional workforce affects the delivery workforce. Delivery work is positively correlated with customer satisfaction. Nevertheless, as a result of research, extrovert personality that has something to do with an energetic activity would not affect on the implementation of their operation. In addition, personal extraversion of workers and drivers in the warehouse can have a significant impact on job commitment and productivity improvement.

• Journal of Embryo Transfer
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• v.32 no.3
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• pp.171-176
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• 2017

This study was conducted to investigate the breeding status of farms to improve the production efficiency of Hanwoo calf. The study was conducted on 45 farms divided into two groups. This study was conducted to investigate the breeding size and breeding area of Hanwoo cows. The average age at first delivery of Hanwoo was 28.7 months. The number of artificial insemination per pregnancy was $1.45{\pm}0.32$, and the number of artificial insemination days after birth was 119.8 days. Conception rates were $75.2{\pm}16.93%$ for small farms and $70.6{\pm}17.46%$ for medium sized farms and $71.4{\pm}11.03%$ for large farms. When we looked at farming methods, 'the farmers using estrus observation aids' had 10.42% higher calf production rate than the 'unused farmers'. The farms vaccinated with IBR and BVDV for breeding cattle showed a 4.41% decrease in abortion, stillbirth and mortality. According to farming conditions, conception rate and delivery rate improved by 3.47% and 18.29%, respectively, when grazing and exercising were performed. Observation, immunization and grazing were found to be important indicators for improving calf production efficiency in Hanwoo farm. This study can be used as a research data to improve the reproductive rate of farmhouse sites through the survey on the breeding status of Hanwoo farmers.

• Journal of Pharmaceutical Investigation
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• v.38 no.5
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• pp.325-329
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• 2008

To enhance the skin delivery of genistein (GT), a soybean isoflavone having anti oxidative activity, comparative formulation studies including liposomes were carried out. GT-loaded conventional and elastic liposomal gel showed the enhanced skin deposition and photoprotection effect as well, in comparison to GT suspension. Elastic liposomes composed of soybean phosphatidylcholine and sodium deoxycholate (85:15, w/w%) were superior to conventional liposomes and were of characteristics as follows: about 130 nm in size; 85% encapsulation efficiency of GT; 5.8% skin deposition of applied dose; 40% inhibition effect on UVB-induced $H_2O_2$ production. Photoprotection effect was closely related to skin deposition of GT. In conclusion, it is possible to suggest that elastic liposomes could be a promising nanocarrier system for efficient skin delivery.

• Animal Bioscience
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• v.36 no.3
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• pp.429-440
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• 2023

Objective: 12-oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid (12-KETE), a metabolite of arachidonic acid, is a strong candidate signal for placenta separation following calf discharge at delivery. In the present study, the effects of 12-KETE on bovine trophoblast cells were investigated to determine its function in the placentome at delivery. Methods: Bovine trophoblast cells derived from blastocysts were used. They were cocultured with or without fibroblasts derived from bovine placentome and/or bovine uterine epithelial cells. 12-KETE was added to the culture medium. Results: Bovine trophoblast cells contained binucleate cells and strongly expressed caudal type homeobox 2 (CDX-2) genes. Addition of 12-KETE to the trophoblast cell colony without feeder cells or that on a fibroblast monolayer induced rapid exfoliation of the colony. After 12-KETE addition, trophoblast cells emitted strong fluorescence caused by the degradation of dye-quenched collagen, indicating that 12-KETE activated matrix metalloproteinase of the trophoblast cells. Exfoliated cell colonies were stained with YOPRO-1, but not propidium iodide (PI). Moreover, DNA fragmentation and Bcl-2 associated X protein (Bax) gene (apoptosis stimulator) upregulation were observed in exfoliated cells, indicating that 12- KETE induced trophoblast cell apoptosis. These results were consistent with previous in vivo observations; however, even a lower concentration of 12-KETE activated trophoblast protease. Meanwhile, fibroblasts derived from the bovine placentome converted arachidonic acid to 12-KETE. Conclusion: These observations indicate that 12-KETE may serve as a signal for placenta separation at delivery.