• 한국시뮬레이션학회:학술대회논문집
• /
• 한국시뮬레이션학회 2003년도 추계학술대회 및 정기총회
• /
• pp.185-192
• /
• 2003

Digital Manufacturing-based production could be very effective in shipbuilding in order to save costs and time, to increase safety for workers, and to prevent bottleneck processes in advance. Digital shipbuilding system, a simulation-based production tool, is being developed to achieve such aspects in Korea. To simulate material flow in a subassembly line at a shipyard, the product, process and resources was modeled for the subassembly process which consisted of several sub-processes such as tack welding, piece alignment, tack welding, and robot welding processes. The analysis and modeling were carried out by using the UML(Unified Modeling Language), an object-oriented modeling method as well as IDEF(Integration DEFinition), a functional modeling tool. Initially, the characteristics of the shop resources were analyzed using the shipyard data, and the layout of the subassembly line was designed with the resources. The production process modeling of the subassembly lines was performed using the discrete event simulation method. Using the constructed resource and process model, the productivity and efficiency of the line were investigated. The number of workers and the variations In the resource performance such as that of a new welding robot were examined to simulate the changes in productivity. The bottleneck process floated according to the performance of the new resources. The proposed model was viewed three-dimensionally in a digital environment so that interferences among objects and space allocations for the resources could be easily investigated

• KSBB Journal
• /
• 제18권2호
• /
• pp.155-160
• /
• 2003

Streptoverticillium morbaraene로부터 미생물 유래 transglutaminase 생산을 위하여 최적의 용존산소 농도를 구명하였다. 용존산소는 용존산소 농도 자동 조절 시스템에 의해 조절되었다. 발효 중 용존산소 농도 조절을 위하여 통기속도는 0.3-3.9 L/min, 교반속도는 260-360 rpm으로 각각 범위를 설정하였다. 용존산소 농도를 조절한 다양한 회분식 배양에서 용존산소가 20%일 때 최대 미생물유래 transgiutaminase 생산이 가능하였다. 최분배양에서 용존산소 농도를 20%로 조절한 경우 미생물유래 transglutaminase 생산은 2.12 U/mL이었고, 용존산소를 조절하지 않은 회분식 배양의 미생물유래 transglutaminase 생산보다 1.1배 향상되었다. 역시 가장 높은 미생물유래 transglutaminase 생산은 용존산소를 20%로 조절한 유가식 배양에서 가능하였으며, 용존산소를 조절하지 않은 회분식 배양의 미생물유래 transglutaminase 생산에 비교해서 1.3배 증가하였다. 최대 건조균체량과 미생물유래 transglutaminase 생산은 각각 13.2 g/L와 2.6 U/mL이었다. 용존산소를 20%로 용존산소 농도 자동 조절 시스템에 의해 조절한 유가식 배양은 미생물유래 transgiutaminase 생산에 적절하였으며 다른 미생물 배양에도 적용할 수 있을 것으로 판단된다.

• 한국생산제조학회지
• /
• 제9권3호
• /
• pp.160-168
• /
• 2000

Hydroforming is a metal forming process that enables circular metal tubes to be formed in to the parts with the complex cross section along the curved axial direction. Recently this hydroforming process is largely used for the production of the automotive parts. This paper presents the results of tube bending and hydroforming simulations in cases of the varying weld line positions of the tube. Ten cases of prebending and hydroforming simulations are carried out to find the optiaml weld line position.

• 한국산업경영시스템학회:학술대회논문집
• /
• 한국산업경영시스템학회 2002년도 춘계학술대회
• /
• pp.387-396
• /
• 2002

Batch processes are a significant class of processes in the process industry and play an important role in the production of high quality speciality materials. Examples include the production of semiconductors, chemicals, pharmaceuticals, and biochemicals. With on-line sensors connected to most batch processes, massive amounts of data are being collected routinely during the batch on easily measured process variables such as temperatures, pressures, and flowrates. In this paper, multivariate SPC charts for on-line monitoring of the progress of new batches are developed which utilize the information in the on-line measurements in real-time. We propose the formation of statistical model which describes the normal operation of a batch at each time interval during the batch operation. An on-line monitoring scheme based on the proposed method can handle both cross-correlation among process variables at any one time and auto-correlation over time. And the control limits for the monitoring charts are established from sound statistical framework unlike previous researches which use the external reference distribution. The proposed charts perform real-time, on-line monitoring to ensure that the batch is progressing in a manner that will lead to a high-quality product or to detect and indicate faults that can be corrected prior to completion of the batch. This approach is capable of tracking the progress of new batch runs, identifying the time periods in which the fault occurred and detecting underlying cause.

• Asian-Australasian Journal of Animal Sciences
• /
• 제15권2호
• /
• pp.166-171
• /
• 2002

The main objective of the present study is to estimate the crossbreeding parameters in respect to serum lysozyme level in broilers. The experiment involved a complete $4{\times}4$ diallel design using four synthetic broiler lines namely Coloured Synthetic Male Line (CSML), White Synthetic Male Line (WSML), Coloured Synthetic Female Line (CSFL) and Naked Neck Line (NNL). The lyophilised Micrococcus lysodeikticus suspension was used to detect the lysozyme level in the serum of birds. The data were analysed by least-squares method to find the effects of genetic and non-genetic factors using appropriate model. The crossbreeding parameters for this trait were estimated by complete diallel model assuming the effect of each synthetic line as fixed. The results indicated that additive and non-additive genetic variation attributed to minor genes at many loci is important for the genetic control of serum lysozyme level in chickens. Total non-additive components of variance also showed significant amount of heterosis in crossbred progenies, and therefore exploitation of non-additive component of variance is possible for improvement in serum lysozyme level in broilers. The overall results suggested that for commercial broiler production system, the selection for specialised line on the basis of serum lysozyme level and subsequent crossing of parent lines could enhance the immunocompetence status in relation to serum lysozyme level in crossbred chickens.

• 대한산업공학회지
• /
• 제35권1호
• /
• pp.15-39
• /
• 2009

Advanced planning and scheduling (APS) refers to a manufacturing management process by which raw materials and production capacity are optimally allocated to meet demand. APS is especially well-suited to environments where simpler planning methods cannot adequately address complex trade-offs between competing priorities. However, most scheduling problems of APS in the real world face both inevitable constraints such as due date, capability, transportation cost, set up cost and available resources. In this survey paper, we address three crucial issues in APS, including basic scheduling model, job-shop scheduling (JSP), assembly line balancing (ALB) model, and integrated scheduling models for manufacturing and logistics. Several evolutionary algorithms which adapt to the problems are surveyed and proposed; some test instances based on the practical problems demonstrate the effectiveness and efficiency of evolutionary approaches.

• Biomolecules & Therapeutics
• /
• 제14권3호
• /
• pp.143-147
• /
• 2006

In the mouse leukemic monocyte cell line RAW 264.7, the vacuolar-type $(H^+)$-ATPase (V-ATPase) inhibitor bafilomycin $A_1$ at 10 and 100 nM decreased cell growth and survival as determined by 3-(4,5-dimethyl(thiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in a concentration-dependent manner. At such concentrations, bafilomycin $A_1$ induced nitric oxide (NO) production through the expression of inducible nitric oxide synthase (iNOS). The bafilomycin $A_1$-induced NO production was inhibited by the NOS inhibitor $N^G$-monomethyl-L-arginine acetate (L-NMMA). Our findings suggest that the V-ATPase inhibitor bafilomycin $A_1$ induces NO production through the expression of iNOS protein.

• 한국의류학회지
• /
• 제24권7호
• /
• pp.995-1003
• /
• 2000

This study examined the role of apparel merchandisers’in Korea. Data were collected by interviewing 7 apparel merchandisers who had worked for major apparel manufacturers. The interviews were analyzed by use of chronologically sequenced events. Korean apparel merchandisers take part in planning and production of the merchandise, sales management, and promotion. Merchandisers’activities related to merchandise planning were as follows: analysis of fashion trend and market, concept evolvement, planning of assortment and volume assortment, time table set up, color pallette decision, fabrication, line adoption, pricing, line preview, production planning, and placing order of materials. Merchandisers’activities related to apparel production were planning and controlling production and consolidation. In sales, merchandisers analyze retail sales and control inventory by reorder or conducting markdown sale. In relation to promotion, apparel merchandisers monitor merchandise advertisement, and educate salesman.

• 산업공학
• /
• 제19권1호
• /
• pp.34-42
• /
• 2006

This paper presents a scheme for a hierarchical production scheduling and control system for a refrigerator factory with mixed model assembly lines. The setting of the factory is as follows. There are three mixed-model assembly lines called main line A, B and C and two batch lines that supply parts to the main lines. For each of the main lines, three work-centers are dedicated to them. The sub-lines and work-centers produce parts in batch type. An incoming production order from the master planner is characterized by its product type, amount, and due date. Under this situation, the proposed scheme has several features to schedule and control the above mentioned factory; 1) select the starting time and the place (assembly line) for an order processing, 2) devise a way to control orders to be processed as scheduled, and 3) reschedule orders when something unexpected happen. Finally, this paper provides a case study where the proposed scheme is applied to.

• 아시안잔디학회지
• /
• 제13권1호
• /
• pp.29-36
• /
• 1999

This study was conducted to make the utmost use of the good traits and to improve the poor traits of zoysiagrass through the production technology for mixed lines sod in addition to breeding. Mixed lines sod was produced by mixing broad or middle leaf line with narrow leaf line by volume, a ratio of 1 to 2. The mixed lines sod of zoysiagrass was superior to the single ling sod, which is used commonly, for the establishment rate, coverage rate, shoot density, texture, leaf color, dormancy period cnd color, and visual quality.