• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.12
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• pp.3632-3637
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• 2009

In this paper, we describe the performance results of the field installation test which is required to practicalize the single-phase MJ81 Switch Point Machine. This product has passed the certified test through performance improvement of driving parts in order to use 3 phase MJ81 Switch Point Machine, which is localized by taking over technology from Alstom and Cogifer when constructing Seoul-Busan rapid-transit railway, without change of the electrical equipment at track-side in domestic existing lines which single-phase 220V is used. KRRI and Samsung SDS have localized the single-phase MJ81 Switch Point Machine to improve the speed and safety of the conventional lines through the existing railway technology development project. For practicalization of this, we should, however, verify the performance through not only field installation test in real lines but also interface test with the interlocking. In this paper we verify the practicality of the domestic single-phase MJ81 Switch Point Machine through analysis on the performance result of the field installation test as well as the research contents for this test. Thereby, in Feb 2009 we have received an order from the Korea Rail Network Authority and are currently installing the single-phase MJ81 Switch Point Machine.

• Applied Microscopy
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• v.3 no.1
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• pp.1-16
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• 1973

A combined cytochemical and electron microscopic study was carried out for the demonstration of acid phosphatase activities in trophozoites of E. histolytica. and E. gingivalis. E. histolytica(YS-27) strain was isolated from liver abscess of 72-year-old man in September 1969, and E. gingivalis (YS-215) strain was collected from gingival crevice of 41-year-old man in January 1972. The amoeba strains were maintained by subculture on diphasic medium, and used throughout the study. The results are summarized as follows; 1. In E. histolytica, the reaction products were distributed evenly over the entire surface of plasma membrane, whereas E. gingivalis showed no activity of acid phosphatase on the plasma membrane, except in the portion of the uroid-like structure. 2. In the cytoplasm, various reaction precipitates were observed in vacuoles of both amoebae; vacuole limiting membrane, vacuole membrane and its contents and lysosome-like structure. Strong enzyme active contents but membrane reaction negative vacuoles were conspicuous in E. gingivalis. Endoplasmic reticulum showed a moderate activity. 3. Granule-like acid phosphatase reaction product was demonstrated in the nucleoplasm of E. gingivalis, but it was negative in E. histolytica.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.8
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• pp.2876-2881
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• 2010

This paper attempts to find out implications based on the comparative analysis of overseas expansion model between the Korean insurance companies and the German one. There are three types of the strategies of the overseas-expansion-model of insurer, i.e. customer-oriented localized strategy, niche market-oriented strategy, and growing market-oriented strategy. From the review of related literatures and through an interview conducted by the insurance specialist, the findings are some differences between Korean and German insurance companies, when they go into foreign insurance markets. Th significant differences between Korean and German insurers are a customer oriented localized strategy and niche market oriented strategy. The Korean insurer shows a strength on the overseas-expansion-strategy, but the most clients of the Korean insurer on overseas markets are also Korean companies and Korean immigrants. The Korean legal expenses insurance market is yet in its embryonic stage, while the German legal expenses insurance company is pushing ahead with a strategy focused on localization and niche market on the legal expenses insurance product. In conclusion, like a case of the German legal expenses insurance company, the Korean insurer needs a customer oriented localized strategy as well as a niche market oriented strategy on the overseas insurance market.

• The Journal of the Korea Contents Association
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• v.5 no.3
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• pp.103-111
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• 2005

By international lighting market's growth and domestic landscape lighting market's growth, the latest lighting market is activated. But, They are doing price competition that domestic lighting technology and development technology of lighting fixtures design do not possess international competitiveness than these change. Specially, as image of area and the country can be influenced greatly by cityscape at present visual point that many interests are converged country and identity establishment of local government, many cities are using force hereupon. Constructs which cityscape is various including natural ecology area of life environment gather and are done Image creation and this people's consciousness and culture living soon inside thing which do speaking by proxy be. Than city's night view nature lighting more than by spectacle lighting along with life lighting to basis materialize can. It is meaning more than thing that fine view of city becomes beautiful simply that night view of city becomes superior, that means that city efficiency and quality of life are exalted by a word. Wish to establish effective lighting technology and new product design process through PLS lighting technical development and 300 W lighting fixtures design development hereupon, and raise domestic spectacle lighting market's localization and domestic lighting market's competitive power furthermore.

• Parasites, Hosts and Diseases
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• v.48 no.4
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• pp.319-324
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• 2010

A family of calcium-dependent protein kinases (CDPKs) is a unique enzyme which plays crucial roles in intracellular calcium signaling in plants, algae, and protozoa. CDPKs of malaria parasites are known to be key regulators for stage-specific cellular responses to calcium, a widespread secondary messenger that controls the progression of the parasite. In our study, we identified a gene encoding Plasmodium vivax CDPK4 (PvCDPK4) and characterized its molecular property and cellular localization. PvCDPK4 was a typical CDPK which had well-conserved N-terminal kinase domain and C-terminal calmodulin-like structure with 4-EF hand motifs for calcium-binding. The recombinant protein of EF hand domain of PvCDPK4 was expressed in Echerichia coli and a 34 kDa product was obtained. Immunofluorescence assay by confocal laser microscopy revealed that the protein was expressed at the mature schizont of P. vivax. The expression of PvCDPK4-EF in schizont suggests that it may participate in the proliferation or egress process in the life cycle of this parasite.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2153-2158
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• 2014

Beclin 1 is a key factor for initiation and regulation of autophagy, which is a cellular catabolic process involved in tumorigenesis. To investigate the role of alternative splicing of Beclin1 in the regulation of autophagy in leukemia cells, Beclin1 mRNA from 6 different types of cell lines and peripheral blood mononuclear cells from 2 healthy volunteers was reversely transcribed, subcloned, and screened for alternative splicing. New transcript variants were analyzed by DNA sequencing. A transcript variant of Beclin 1 gene carrying a deletion of exon 11, which encoded a C-terminal truncation of Beclin 1 isoform, was found. The alternative isoform was assessed by bioinformatics, immunoblotting and subcellular localization. The results showed that this variable transcript is generated by alternative 3' splicing, and its translational product displayed a reduced activity in induction of autophagy by starvation, indicating that the spliced isoform might function as a dominant negative modulator of autophagy. Our findings suggest that the alternative splicing of Beclin 1 might play important roles in leukemogenesis regulated by autophagy.

• KSBB Journal
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• v.17 no.4
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• pp.370-375
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• 2002

Isolation of a gene and determination of its expression pattern are essential in understanding its function. Among the genes localized in 12ql3, stSG3435 EST was chosen to study its expression pattern. The full-length CDNA was cloned by screening of human brain CDNA library and its sequence was determined by serial deletion followed by automated sequencing of the clones with overlapping fragments. The sequence analysis revealed that stSG 3435 CDNA displayed 100% identity to human MYGI and 86% identity to mouse melanocyte proliferation gene-1 (Gamm 1) originally identified from melanocyte, suggesting that MYGI determined by Northern blot analysis revealed the strongest expression in testes with ubiquitous expression in all the tissues tested. In order to investigate the cellular localization of its protein product, the green fluorescence protein gene was fused into the full-length coding sequence of MYGI, Transfection of the fusion construct followed by confocal microscopy resulted in the green fluorescence signal as a punctate state in cytoplasm indication that MYGI was localized in one of the cellular organelles.

• Korean journal of communication and information
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• v.46
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• pp.354-386
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• 2009

Global women's magazines have been approached as a significant site for exploring the dynamic interaction between global and local forces. Unlike other global media products which are imported from overseas, global women's magazines are published through the cooperation with local companies. These ownership patterns allow local editions of global women's magazines to negotiate the tension and contradiction between the global media and local publishers. Thus, the main purpose of this research is to investigate the dialectic interaction between the global and local forces in the production of international women's magazines in Korea. To explore the dynamic interaction between the global and local forces, both globalization and localization efforts of international women's magazines which occur during the production process were examined through in-depth interviews with personnel in the magazine industry. The result of this research showed that international women's magazines are not a mere part of global media but a 'glocalized' media product, which carry local content via global formats. The form of international women's magazines seems to be more globalized or standardized, while the content (text) is relatively localized by reflecting local readers' interests and the cultural values of Korean society.

• Korean Business Review
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• v.19 no.2
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• pp.117-140
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• 2006

The purpose of this study is to activate tourism industry in Sorak area where faces crisis arising from environmental change. To achieve its' purpose, this study investigated operational problem concerning about development of tourism in Sorak area and politic problem concerning about tourism resource in order to devise activation of regional economy through its effective conservation and development. and at same time, compared difference of perception between tourist and worker of tourism empirically in aspect of product, service, public marketing in order to activate regional tourism industry through effective development of tourism resource. Finally, this study also suggested countermeasure suitable for the above stated. As seeing above results, this study contributes to promote tourism in Sorak area by developing tourism resource in vein of localization age which means local area can be center of the world in consideration of globalization age without national boundary. Conclusively, it can be said that segmentation of tourism market based on tourist's interest needs to be accomplished through connection between regional limitation and academic research with making use of advantage of abundant tourism resource in Sorak area. what is more, supplement of attention. to improvement of service quality can cause more positive effect.

• Culinary science and hospitality research
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• v.16 no.4
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• pp.15-27
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• 2010

As most companies in the world are much interested in the overseas market as well as in the domestic market, many Korean food service enterprises came to focus on extending their branches to the overseas market. However, lack of business strategies including market research, marketing strategies, localization, etc. has made them continue to fail in market entry. The purpose of this study is to develop entry mode of determinants of Korean food service enterprises, considering their characteristic factors and environment factors in the overseas market. To do this, companies which have a head quarter in Korea and over 2 year business experience in the overseas market were chosen and used for a self-administered questionnaire survey. Statistical processing, including descriptive statistics, logistic regressing analysis, and multi regression analysis using an SPSS/PC 12.0 statistical package were conducted The result is as follows. First, explanation suitability was 85% of the entry mode in the overseas market. Second, as business size was smaller, product differentiation was higher, and CEO's will for success in the overseas market was higher, independent entry mode in the overseas market was likely to he chosen. Lastly, as the uncertainty of demand and trade barrier were lower, and a sociocultural gap was smaller, independent entry mode in the overseas market was likely to be chosen.