• Title/Summary/Keyword: Product Damage

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Antioxidative and Probiotic Properties of Lactobacillus gasseri NLRI-312 Isolated from Korean Infant Feces

  • Kim, H.S.;Jeong, S.G.;Ham, J.S.;Chae, H.S.;Lee, J.M.;Ahn, C.N.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.9
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    • pp.1335-1341
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    • 2006
  • We selected a Lactobacillus spp. from Korean healthy infant feces based upon their antioxidant activity. This strain was identified as Lactobacillus gasseri by 16S rDNA sequencing, and named Lactobacillus gasseri NLRI-312. In the present study, we investigate the protective effect of this strain on the $H_2O_2$ induced damage to cellular membrane lipid and DNA in Jurkat cells. To estimate the extent of cellular lipid peroxidation inhibition, MDA (malondialdehyde) was measured, and DNA damage was tested by the comet assay. We also examined probiotic properties including tolerance to acid and bile, antibiotic resistance. From the results obtained, the supplementation of Jurkat cells with NLRI-312 decreased in DNA damage, while no effect was shown on MDA decrease. In probiotic properties, this strain was resistance to both acid and bile, showed considerably higher survival when incubated in pH 2 or 1% bile salts (w/v). We concluded that the NLRI-312 could be used as potential probiotic bacteria, with the effect of reducing DNA damage induced by $H_2O_2$.

Structural Damage Detection through System Identification (시스템 동정을 통한 구조물의 결함 탐지)

  • Koh, Bong-Hwan;Nagarajaiah, S.;Phan, M.Q.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.05a
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    • pp.1223-1228
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    • 2006
  • This paper presents an experimental investigation of a recently developed Kronecker Product (KP) method to determine the type, location, and intensity of structural damage from an identified state-space model of the system. Although this inverse problem appears to be highly nonlinear, the system mass, stiffness, and damping matrices are identified through a series of transformations, and with the aid of the Kronecker product, only linear operations are involved in the process. Since a state-space model can be identified directly from input-output data, an initial finite element model and/or model updating are not required. The test structure is a two-degree-of-freedom torsional system in which mass and stiffness are arbitrarily adjustable to simulate various conditions of structural damage. This simple apparatus demonstrates the capability of the damage detection method by not only identifying the location and the extent of the damage, but also differentiating the nature of the damage. The potential applicability of the KP method for structural damage identification is confirmed by laboratory test.

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Response Characteristics of the Cushion Materials for Packaging of the Pears by Mechanical Shock during Transportation (유통 중 기계적 충격에 의한 배 포장완충재의 응답 특성)

  • Jung, Hyun-Mo;Kim, Man-Soo;Kim, Ghi-Seok;Cho, Byeong-Kwan
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.13 no.1
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    • pp.25-28
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    • 2007
  • Physical damage on fruits and vegetables caused by shock degrades the value of product in the fresh market. In order to design a product/package system to protect the product, the peak acceleration or G force to the product that causes shock damage needs to be determined. Shock cushion packaging is applied to protect goods of all kinds. It can be adapted in their shape to any product to be packed, so that its shock absorbing properties is determined by geometry of the product. The shape of a cushion can be adapted to the expected shock loads. To analyze the response properties of cushion materials for packaging of the pears for optimum packaging design during transportation, shock tests were carried out. Shock acceleration that is happened in pears were appeared very high by $25{\sim}30G$ in the input shock acceleration of 14.1618 G that was measured in transportation road. This means that the pears receive the shock acceleration more than maximum double itself and the damage by this can happen and the shock acceleration increase in case use PE tray cup and PE net in fruits, the use of corrugated fiberboard pad may become one method that it can reduce the damage by the shock in packaging of fruits.

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A Liability for Damage caused by Drug (의약품 부작용과 손해배상)

  • Song, Jinsung
    • The Korean Society of Law and Medicine
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    • v.21 no.3
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    • pp.77-116
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    • 2020
  • The use of drugs that reflect the experiences and achievements of modern science has given human being the benefits of treating diseases and improving health conditions. However, in addition to the benefits of those, medicines have inherently inevitable adverse reactions. Many countries are taking measures such as market entry regulations or post-marketing surveillance to minimize damage caused by drug side effects, but the occurrence of side effects cannot be eliminated. Although the damage is force majeure, in some cases, the doctor who prescribed the drug or the pharmacist who administered the drug may have to compensate for the damage. The liability depends on whether the side effects were known in advance, the type of medicine, etc. On the other hand, in some cases, drug manufacturer may have to take liability for the side effect itself. As it is not easy for victims to be compensated for damages in those cases, many countries, including Korea, are setting to protect victims through the Product Liability Act. Drugs are also one of the product, so liability set by the Product Liability Act may apply. Even before the enactment and enforcement of the Product Liability Act, damage caused by drug has occurred. To resolve them, precedents have developed case law, which have many similarities with the Product Liability Act, but also have differences. Damage caused by drug manufactured prior to the enforcement of the Product Liability Act may occur in the future. In this context, the legal principles of the case laws will remain valid and be applied. This is an important reason to review the case law of precedents.

A Survey on Cognition Levels of Consumers and Producers for Product Liability (제조물책임에 대한 소비자와 생산자의 인식수준에 관한 연구)

  • Kim Jin Tae;Jeon Young Rok
    • Journal of the Korea Safety Management & Science
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    • v.7 no.3
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    • pp.109-120
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    • 2005
  • A company is liable for its products and has the responsibility to make good on any loss or damage incurred by the user of its product. The purpose of the Product Liability Act(PLA) is to protect consumers against damage caused by defective products, and contribute to the safety of the citizen's life and the sound development of the national economy by regulating the liability of manufacturers, etc. for damages caused by the defectiveness of their products. In this study, the cognition levels of consumers and producers for PLA were surveyed. The cognition levels of four factors of acknowledgement, comprehension, necessity and impact for PLA were assessed. The results were as follows : i) Acknowledgement and comprehension levels of consumer were assessed low but they assessed necessity and impact of PLA high; ii) Producers assessed necessity and impact of PLA higher than their acknowledgement and comprehension levels; iii) Overall cognition levels of producers were higher than those of consumers.

A Study on Accelerated Fatigue Life Testing for Industrial Inverter (산업용 인버터의 가속 피로수명 평가에 관한 연구)

  • Lee, Sanghoon;Kim, Won-Jin
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.21 no.6
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    • pp.67-73
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    • 2022
  • Industrial inverters are used in a variety of fields for electric power supply. They may be exposed to vibration and heat once they are installed. This study focused on a framework of accelerated life testing of an industrial inverter considering fatigue damage as the primary source of deterioration. Instead of analyzing detailed failure mechanisms and the product's vulnerability to them, the potential of fatigue failure is considered using the fatigue damage spectrum calculated from the environmental vibration signals. The acceleration and temperature data were gathered using field measurement and spectral analysis was conducted to calculate the vibration signal's power spectral density (PSD). The fatigue damage spectrum is then calculated from the input PSD data and is used to design an accelerated fatigue life testing. The PSD for the shaker table test is derived that has the equivalent fatigue damage to the original input signal. The tests were performed considering the combined effect of random vibration and elevated temperature, and the product passed all the planned tests. It was successfully demonstrated that the inverter used in this study could survive environmental vibration up to its guarantee period. The fatigue damage spectrum can effectively be used to design accelerated fatigue life testing.

Estimation of the Allowable Bio-shock Fragility Index of Fruits for Optimum Packaging Design (적정 포장설계를 위한 과실의 바이오 허용 충격지수 추정)

  • Kim, Ghi-Seok;Jung, Hyun-Mo;Kim, Ki-Bok;Kim, Man-Soo
    • Journal of Biosystems Engineering
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    • v.32 no.6
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    • pp.416-421
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    • 2007
  • Physical damage to fruits and vegetables caused by shock degrades the value of product in the fresh market. In order to design a product/packaging system to protect the product, the G-factor to the product that causes shock damage needs to be determined. The shock fragility of organisms such as fruits with a concept correspondent to the G-factor of industrial products was calculated and we defined the allowable bio-shock fragility index as the value divided peak acceleration that was generated in safe drop height by standard acceleration of gravity. We did modeling for safe drop hight that would prevent fruits from damage by drop tests and tried to estimate the allowable bio-shock fragility index of pears and apples for optimum packaging design. The bio-shock fragility index of pears was in the range of $0.74{\sim}2.29\;G$, while apples had a slightly higher value than that of pears, of $0.51{\sim}2.98\;G$. This result shows accordance with the general fact that apples have a firmer structure and get less damage from the same impact. Based on this result, it is possible to create an optimum packaging design by providing a damage standard by impact.

EVALUATION OF HAIR DAMAGE BASED ON MEASUREMENTS OF LABILE PROTEIN

  • Inoue, Takafumi;Ito, Mayumi;Kizawa, Kenji;Iwamoto, Yoshimichi
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.142-160
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    • 2003
  • Most consumers have noted hair damage following coloring treatments. Proper evaluation of hair bleaching products must be performed using quantitative assessments of hair damage, though they are difficult, because of the slight fluctuations in hair composition. In the present study, we utilized a sensitive evaluation method for hair damage and found that the amount of soluble protein fraction extracted from hair under a reducing condition, termed labile protein, dramatically increased after bleaching.(omitted)

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Calculation of The Core Damage & FP Release Behavior for The PHEBUS FPT0 Similar to Cold Leg Break Accident Using MELCOR

  • Park, Jong-Hwa;Cho, Song-Won;Kim, Hee-Dong
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05b
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    • pp.637-642
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    • 1996
  • This paper presents the analysis results for the core degradation processes and the fission product release of the PHEBUS FPT0 experiment using MELCOR1.8.3. The objective of this study is to assess models associated with the core damage and fission product behavior in MELCOR. The calculation results were much improved through sensitivity studies. Thermal/hydraulic behavior in the core and the circuit was well predicted under the intact core geometry. In non-eutectic model case. the UO$_2$ dissolution model in the MELCOR always showed such a tendency that the resulting dissolved UO$_2$ mass was small at the highly oxidized condition due to the model logic. Total H$_2$ generation mass was underpredicted because the stiffner was not modeled and the liner in the shroud was not allowed to be oxidized in MELCOR. Some difficulties were found in modeling the activation product were solved by manipulating the RN input associated with the initial fission product inventory. These problem were occurred because there are no control rod model in MELCOR. Generally the fission product release ratio showed a similar trend compared with the measured data except the activation product. which have no model to simulate in MELCOR.

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PL PREVENTION PROGRAM FOR EXPORT INDUSTRIES (PL 대응책에 대한 고찰)

  • 황의철
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.9 no.14
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    • pp.35-43
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    • 1986
  • PL(product liability) is a major social, market, and economic force. The legal obligation of manufacturers and sellers to compensate for injury or damage caused by defective products is not a recent phenomenon. The concept of Product liability has been in existence for many years, but its emphasis has changed recently. This PL prevention program has shown that the two area of product quality assurance one is a PLD(product liability defense) and the other is a PLP(product liability prevention.

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