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Urinary Excretion of Various Urinary Proteins in Children with Vesicoureteral Reflux (방광요관 역류증 환아에서의 다양한 요단백의 배설)

  • Jung, Da Eun;Koo, Ja Wook
    • Clinical and Experimental Pediatrics
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    • v.46 no.10
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    • pp.977-982
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    • 2003
  • Purpose : This study aimed to examine the excretion of various urinary proteins in children with a history of urinary tract infection(UTI), with or without vesicoureteral reflux(VUR) or reflux nephropathy, and to identify means of predicting the severity of VUR or the presence of reflux nephropathy as indicated by these markers, and to know how these markers are changed after resolution of VUR. Methods : We studied 30 children with previous UTI, without VUR and renal scarring(group I), 12 children with VUR, without evidence of renal scarring(group II), and 34 children with VUR and renal scarring(group III). 24-hour or 12-hour urine ${\beta}_2$ microglobulin(${\beta}_2$ MG), microalbumin and N-acetyl-${\beta}$-D-glucosaminidase(NAG) were measured in each child. Urinary protein excretions were analyzed according to the degree of VUR(mild VUR : a grade reflux I-III, severe VUR : a grade reflux IV-V). Cases of bilateral VUR were graded by the higher grade of reflux detected. A total of 46 children with primary VUR were followed. Among these patients, VUR was completely resolved in 16 children. Voiding cystourethrography(VCUG) and DMSA scan were performed every year. Values for urinary markers were estimated every year. Results : 24 or 12 hour urine microalbumin and NAG excretions were significantly increased in group III compared to group I(microalbumin : $27.7{\pm}26.0mg/gCr$ vs $15.0{\pm}10.7mg/gCr$, P<0.05, NAG : $15.2{\pm}18.7U/gCr$ vs $3.4{\pm}2.2U/gCr$, P<0.05). Urinary ${\beta}_2$ MG excretions were not significantly different between groups. Urinary NAG excretions were elevated in the group of children with severe VUR compared to mild VUR($26.8{\pm}27.1U/gCr$ vs $7.6{\pm}3.8U/gCr$, P<0.05). After resolution of VUR, urinary microalbumin and NAG excretions were decreased(P<0.05). Conclusion : Urinary microalbumin and NAG may be useful clinical indicators to predict the presence of reflux nephropathy and the resolution of VUR. Especially, urinary NAG excretions may be used as a possible method to predict the severity of VUR.

Monitoring of a Time-series of Land Subsidence in Mexico City Using Space-based Synthetic Aperture Radar Observations (인공위성 영상레이더를 이용한 멕시코시티 시계열 지반침하 관측)

  • Ju, Jeongheon;Hong, Sang-Hoon
    • Korean Journal of Remote Sensing
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    • v.37 no.6_1
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    • pp.1657-1667
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    • 2021
  • Anthropogenic activities and natural processes have been causes of land subsidence which is sudden sinking or gradual settlement of the earth's solid surface. Mexico City, the capital of Mexico, is one of the most severe land subsidence areas which are resulted from excessive groundwater extraction. Because groundwater is the primary water resource occupies almost 70% of total water usage in the city. Traditional terrestrial observations like the Global Navigation Satellite System (GNSS) or leveling survey have been preferred to measure land subsidence accurately. Although the GNSS observations have highly accurate information of the surfaces' displacement with a very high temporal resolution, it has often been limited due to its sparse spatial resolution and highly time-consuming and high cost. However, space-based synthetic aperture radar (SAR) interferometry has been widely used as a powerful tool to monitor surfaces' displacement with high spatial resolution and high accuracy from mm to cm-scale, regardless of day-or-night and weather conditions. In this paper, advanced interferometric approaches have been applied to get a time-series of land subsidence of Mexico City using four-year-long twenty ALOS PALSAR L-band observations acquired from Feb-11, 2007 to Feb-22, 2011. We utilized persistent scatterer interferometry (PSI) and small baseline subset (SBAS) techniques to suppress atmospheric artifacts and topography errors. The results show that the maximum subsidence rates of the PSI and SBAS method were -29.5 cm/year and -27.0 cm/year, respectively. In addition, we discuss the different subsidence rates where the study area is discriminated into three districts according to distinctive geotechnical characteristics. The significant subsidence rate occurred in the lacustrine sediments with higher compressibility than harder bedrock.

Pain and Factors Influencing Its Management in Patients with Terminal Cancer (말기 암환자의 통증 및 통증관리에 영향을 미치는 요인)

  • Yun, Young-Ho;Heo, Dae-Seog;Kim, Hong-Soo;Ou, Sang-Woo;Yoo, Tai-Woo;Kim, You-Young;Huh, Bong-Yul
    • Journal of Hospice and Palliative Care
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    • v.1 no.1
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    • pp.23-29
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    • 1998
  • Purpose : Validity of WHO guideline of cancer pain management has been proven and many trials were done for resolution of inadequate management of cancer pain. We assessed the severity of pain in terminal cancer patients and patient's characteristics influencing inadequate pain management. Methods : This study was done on 100 patients who was confirmed as terminal in Seoul National University Hospital from lune 1997 to November. For getting the informations about dermographic and medical characteristics such as performance and metastasis, and drug-adjusted pain severity the patients, we reviewed the medical records and interview the patients. we assessed the adequacy of prescribed analgesics with WHO guidelines of pain management, and patient's characteristics influencing on adequacy of pain management. Results : 85.0 percent of cancer patient had pain when diagnosed as terminal cancer and 68% of patient had pain above moderate severity. 38.0 percent of those were given inadequate pain management and the greater pain severity, the less adequate(P<0.001). Sex, age, primary site of cancer, metastasis, symptoms such as depression and anxiety, and performance were not significant. Conclusion : Despite guidelines for pain management, many patients with terminal cancer received inadequate pan management. Their is a need for education about evaluation of pain and guidelines of pain management.

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Design and Performance Analysis of an Off-Axis Three-Mirror Telescope for Remote Sensing of Coastal Water (연안 원격탐사를 위한 비축 삼반사경 설계와 성능 분석)

  • Oh, Eunsong;Kang, Hyukmo;Hyun, Sangwon;Kim, Geon-Hee;Park, YoungJe;Choi, Jong-Kuk;Kim, Sug-Whan
    • Korean Journal of Optics and Photonics
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    • v.26 no.3
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    • pp.155-161
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    • 2015
  • We report the design and performance analysis of an off-axis three-mirror telescope as the fore optics for a new hyperspectral sensor aboard a small unmanned aerial vehicle (UAV), for low-altitude coastal remote sensing. The sensor needs to have at least 4 cm of spatial resolution at an operating altitude of 500 m, $4^{\circ}$ field of view (FOV), and a signal to noise ratio (SNR) of 100 at 660 nm. For these performance requirements, the sensor's optical design has an entrance pupil diameter of 70 mm and an F-ratio of 5.0. The fore optics is a three-mirror system, including aspheric primary and secondary mirrors. The optical performance is expected to reach $1/15{\lambda}$ in RMS wavefront error and 0.75 in MTF value at 660 nm. Considering the manufacturing and assembling phase, we determined the alignment compensation due to the tertiary mirror from the sensitivity, and derived the tilt-tolerance range to be 0.17 mrad. The off-axis three-mirror telescope, which has better performance than the fore optics of other hyperspectral sensors and is fitted for a small UAV, will contribute to ocean remote-sensing research.

Taking of Evidence in International Arbitration Procedure - focusing on 2010 IBA Rules on the Taking of Evidence in International Arbitration (국제중재 절차내에서 증거조사 : 국제변호사협회(IBA)의 2010 증거규칙을 중심으로)

  • CHUNG, Hong-Sik
    • Journal of Arbitration Studies
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    • v.21 no.3
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    • pp.21-54
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    • 2011
  • International commercial arbitration has established itself as the primary dispute resolution mechanism for international business transactions. Certainly, there are commonly-accepted standards that have evolved to reflect an internationally-harmonized approach to issues relating to the taking of evidence. This is reflected in International Bar Association("IBA") Rules for Taking of Evidence in International Evidence("IBA Rules"). This IBA Rules were revised in 2010. Designed to assist parties in determining what procedures to use in their particular case, IBA Rules present some of the methods for conducting international arbitration proceedings. Parties and arbitral tribunals may adopt IBA Rules in whole or in part - at the time of drafting the arbitration clause in a contract or once an arbitration commences - or they may use them as guidelines. They supplement applicable national laws and institutional or ad hoc rules. The IBA Rules were an ambitious undertaking, designed to overcome fundamental cultural differences relating to the taking of evidence under different national court systems. While it is difficult to assess how frequently the IBA Rules are actually adopted by parties, it is fair to say that they have had a considerable influence on the practice of taking evidence in international arbitration. This article mainly describes the essential provisions of IBA Rules, as revised in 2010, including but not limited to production of document, witnesses of fact, party-appointed experts, and tribunal-appointed experts. It also provides a comparison of relevant procedural rules of civil law and common law systems to each of the above mentioned provisions. It is important for arbitration practitioners to understand the differences in the taking of evidence under civil law and common law systems, respectively. This article will be helpful for practitioners and academics not only to understand the revised IBA Rules themselves but also to prepare for, and adequately deal with, the frictions that may arise as a result of the differences in approach for taking evidences. Indeed, so prepared, the arbitration practitioner will be able to anticipate the expectations, perceptions and the conduct of the parties, their counsel and the tribunal members.

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A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma Treated with Lobectomy (폐엽절제를 통한 BALT 림프종 치료 1 예)

  • Choi, Won Sub;Cho, Jae Hyun;Hwang, Young Il;Jang, Seung Hun;Kim, Dong-Gyu;Jun, Sun-Young;Min, Kwangseon;Lee, In Jae;Lee, Jae Woong;Jung, Ki-Suck
    • Tuberculosis and Respiratory Diseases
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    • v.62 no.5
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    • pp.427-431
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    • 2007
  • The bronchus-asociated lymphoid tissue(BALT) lymphoma is a low-grade primary malignant lymphoma that originates from bronchus associated lymphoid tissue. A 67-year-old woman was admitted for evaluation of cough, sputum, rhinorrhea which had persisted for one month. Physical examination showed decreased breathing sound on the left upper lung field. High resolution chest computed tomography demonstrated consolidation which showed air-bronchogram and surrounding ground glass opacity in left upper lobe. These findings implicated inactive tuberculosis, organizing pneumonia, or bronchiolo-alveolar carcinoma. The histologic findings from percutaneous needle aspiration biopsy revealed aggregated atypical small lymphoid cells with lymphoepithelial lesions. With immunohistochemical staining, the atypical lymphoid cells reacted positively with CD 20 antibody and negatively with CD 3 antibody. Thus, we could diagnosed her as a patient with BALT lymphoma. After left upper lobectomy, she has been well without recurrence of the disease for 14 months. In this country of Republic of Korea, it was the 1st case of BALT lymphoma surgically treated when histological diagnosis had been done. Based on this case, we wanted to demonstrate the importance of early histological diagnosis and treatment of BALT lymphoma.

Conceptual Design Study of NISS onboard NEXTSat-1

  • Jeong, Woong-Seob;Park, Sung-Joon;Park, Kwijong;Lee, Dae-Hee;Moon, Bongkon;Pyo, Jeonghyun;Park, Youngsik;Kim, Il-Joong;Park, Won-Kee;Lee, Duk-Hang;Park, Chan;Ko, Kyeongyeon;Nam, Ukwon;Han, Wonyong;Im, Myungshin;Lee, Hyung Mok;Lee, Jeong-Eun;Shin, Goo-Hwan;Chae, Jangsoo
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.82.2-82.2
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    • 2013
  • The NISS (Near-infrared Imaging Spectrometer for Star formation history) onboard NEXTSat-1 is being developed by KASI. The NISS will perform the imaging low-resolution spectroscopic observation in the near-infrared range for nearby galaxies, low background regions, starforming regions and so on. The off-axis reflecting telescope with a wide field of view (2 deg. ${\times}$ 2 deg.) will be operated in the wavelength range from 0.95 to $3.8{\mu}m$. In order to reduce thermal noise, a telescope and a HgCdTe infrared sensor will be cooled down to 200K and 80K, respectively. To evade a stray light outside a field of view and use limited space efficiently, the NISS adopted the off-axis reflective optical system. The primary and secondary mirrors, optomechanical part and mechanical structure were designed to use the same material. It will lessen the degradation of optical performance due to a thermal variation. The purpose of NISS is the observation of cosmic near-infrared background in the wide wavelength range as well as the detection of near-infrared spectral lines in nearby galaxies, cluster of galaxies and star forming regions. It will give us less biased information on the star formation history. In addition, we will demonstrate the space technologies related to the development of the Korea's leading near-infrared instrument for the future large infrared telescope, SPICA.

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1SWASP J093010.78+533859.5: A Possible Hierarchical Quintuple System

  • Koo, Jae-Rim;Lee, Jae Woo;Lee, Byeong-Cheol;Kim, Seung-Lee;Lee, Chung-Uk;Hong, Kyeongsoo;Lee, Dong-Joo;Rey, Soo-Chang
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.71.1-71.1
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    • 2013
  • Among quadruples or higher multiplicity stars, only a few binary systems have been discovered. They are important targets to understand the formation and evolution of multiple stellar systems because we can obtain accurate stellar parameters from photometric and spectroscopic studies. We present the observational results of this kind of rare object 1SWASP J093010.78+533859.5, for which the doubly eclipsing feature had been detected previously from the SuperWASP photometric archive. Individual PSF photometry for two objects with a separation of about 1.9 arcsec was performed for the first time in this study. Our time-series photometric data show that the brighter object A is an Algol-type detached eclipsing binary with an orbital period of 1.3 days and the fainter B is a W UMa-type contact eclipsing binary with a period of 0.23 days. Using the high-resolution optical spectra, we obtained well-defined radial velocity variations of the system A. Furthermore, stationary spectral lines were detected and should have originated from the other stellar component, which was confirmed by the third object contribution from the light curve analysis. No spectral feature of the system B was detected, probably due to its faintness. We obtained the binary parameters and the absolute dimensions from each light curve synthesis. The primary and secondary components of the system A have a spectral type of K1 and K5 main sequences, respectively. Two components of system B have nearly the same type of K3 main sequence. Light variations at out of eclipses were appeared in both systems, interpreting as the effect of stellar spots on these late spectral type stars. We estimated the distances to the systems A and B individually. They may have similar distances of about 70 pc and seem to be gravitationally bound with a separation of about 130 AU. In conclusion, we suggest that 1SWASP J093010.78+533859.5 is a quintuple stellar system with a hierarchical structure of a triple system A(ab)c and a binary system B(ab).

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Seismic interval velocity analysis on prestack depth domain for detecting the bottom simulating reflector of gas-hydrate (가스 하이드레이트 부존층의 하부 경계면을 규명하기 위한 심도영역 탄성파 구간속도 분석)

  • Ko Seung-Won;Chung Bu-Heung
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.06a
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    • pp.638-642
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    • 2005
  • For gas hydrate exploration, long offset multichannel seismic data acquired using by the 4km streamer length in Ulleung basin of the East Sea. The dataset was processed to define the BSRs (Bottom Simulating Reflectors) and to estimate the amount of gas hydrates. Confirmation of the presence of Bottom Simulating reflectors (BSR) and investigation of its physical properties from seismic section are important for gas hydrate detection. Specially, faster interval velocity overlying slower interval velocity indicates the likely presences of gas hydrate above BSR and free gas underneath BSR. In consequence, estimation of correct interval velocities and analysis of their spatial variations are critical processes for gas hydrate detection using seismic reflection data. Using Dix's equation, Root Mean Square (RMS) velocities can be converted into interval velocities. However, it is not a proper way to investigate interval velocities above and below BSR considering the fact that RMS velocities have poor resolution and correctness and the assumption that interval velocities increase along the depth. Therefore, we incorporated Migration Velocity Analysis (MVA) software produced by Landmark CO. to estimate correct interval velocities in detail. MVA is a process to yield velocities of sediments between layers using Common Mid Point (CMP) gathered seismic data. The CMP gathered data for MVA should be produced after basic processing steps to enhance the signal to noise ratio of the first reflections. Prestack depth migrated section is produced using interval velocities and interval velocities are key parameters governing qualities of prestack depth migration section. Correctness of interval velocities can be examined by the presence of Residual Move Out (RMO) on CMP gathered data. If there is no RMO, peaks of primary reflection events are flat in horizontal direction for all offsets of Common Reflection Point (CRP) gathers and it proves that prestack depth migration is done with correct velocity field. Used method in this study, Tomographic inversion needs two initial input data. One is the dataset obtained from the results of preprocessing by removing multiples and noise and stacked partially. The other is the depth domain velocity model build by smoothing and editing the interval velocity converted from RMS velocity. After the three times iteration of tomography inversion, Optimum interval velocity field can be fixed. The conclusion of this study as follow, the final Interval velocity around the BSR decreased to 1400 m/s from 2500 m/s abruptly. BSR is showed about 200m depth under the seabottom

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Prediction of Rice Yield in Korea using Paddy Rice NPP index - Application of MODIS data and CASA Model - (논벼 NPP 지수를 이용한 우리나라 벼 수량 추정 - MODIS 영상과 CASA 모형의 적용 -)

  • Na, Sang Il;Hong, Suk Young;Kim, Yi Hyun;Lee, Kyoung Do;Jang, So Young
    • Korean Journal of Remote Sensing
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    • v.29 no.5
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    • pp.461-476
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    • 2013
  • Carnegie-Ames-Stanford Approach (CASA) model is one of the most quick, convenient and accurate models to estimate the NPP (Net Primary Productivity) of vegetation. The purposes of this study are (1) to examine the spatial and temporal patterns of vegetation NPP of the paddy field area in Korea from 2002 to 2012, and (2) to investigate how the rice productivity responded to inter-annual NPP variability, and (3) to estimate rice yield in Korea using CASA model applied to MOderate Resolution Imaging Spectroradiometer (MODIS) products and solar radiation. MODIS products; MYD09 for NIR and SWIR bands, MYD11 for LST, MYD15 for FPAR, respectively from a NASA web site were used. Finally, (4) its applicability is to be reviewed. For those purposes, correlation coefficients (linear regression for monthly NPP and accumulated NPP with rice yield) were examined to evaluate the spatial and temporal patterns of the relations. As a result, the total accumulated NPP and Sep. NPP tend to have high correlation with rice yield. The rice yield in 2012 was estimated to be 526.93kg/10a by accumulated NPP and 520.32 kg/10a by Sep. NPP. RMSE were 9.46kg/10a and 12.93kg/10a, respectively, compared with the yield forecast of the National Statistical Office. This leads to the conclusion that NPP changes in the paddy field were well reflected rice yield in this study.