• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.328-328
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• 2007

Large area matrix-addressed image detectors are a recent technology for x-ray imaging with medical diagnostic and other applications. The imaging properties of x-ray pixel detectors depend on the quantum efficiency of x-rays, the generated signal of each x-ray photon and the distribution of the generated signal between pixels. In a phosphor coated detector the light signal is generated by electrons captured in the phosphor screen. In our study we simulated the lateral spread distributions for phosphor coupled detector by Monte Carlo simulations. Most simulations of such detectors simplify the setup by only taking the conversion layer into account neglecting behind. The Monte Carlo code MCNPX has been used to simulate the complete interaction and subsequent charge transport of x-ray radiation. This has allowed the analysis of charge sharing between pixel elements as an important limited factor of digital x-ray imaging system. The parameters are determined by lateral distribution of x-ray photons and x-ray induced electrons. The primary purpose of this study was to develop a design tool for the evaluation of geometry factor in the phosphor coupled optical imaging detector. In order to evaluate the spatial resolution for different phosphor material, phosphor geometry we have developed a simulation code. The developed code calculates the energy absorption and spatial distribution based on both the signal from the scintillating layer and the signal from direct detection of x-ray in the detector. We show that internal scattering contributes to the so-called spatial resolution drop of the image detector. Results from the simulation of spatial distribution in a phosphor pixel detector are presented. The spatial resolution can be increased by optimizing pixel size and phosphor thickness.

• Korean Journal of Remote Sensing
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• v.29 no.3
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• pp.275-291
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• 2013

Monitoring the global Gross Primary Pproduction (GPP) is relevant to understanding the global carbon cycle and evaluating the effects of interannual climate variation on food and fiber production. GPP, the flux of carbon into ecosystems via photosynthetic assimilation, is an important variable in the global carbon cycle and a key process in land surface-atmosphere interactions. The Moderate-resolution Imaging Spectroradiometer (MODIS) is one of the primary global monitoring sensors. MODIS GPP has some of the problems that have been proven in several studies. Therefore this study was to solve the regional mismatch that occurs when using the MODIS GPP global product over Korea. To solve this problem, we estimated each of the GPP component variables separately to improve the GPP estimates. We compared our GPP estimates with validation GPP data to assess their accuracy. For all sites, the correlation was close with high significance ($R^2=0.8164$, $RMSE=0.6126g{\cdot}C{\cdot}m^{-2}{\cdot}d^{-1}$, $bias=-0.0271g{\cdot}C{\cdot}m^{-2}{\cdot}d^{-1}$). We also compared our results to those of other models. The component variables tended to be either over- or under-estimated when compared to those in other studies over the Korean peninsula, although the estimated GPP was better. The results of this study will likely improve carbon cycle modeling by capturing finer patterns with an integrated method of remote sensing.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.605-610
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• 2014

Chronic liver diseases, including cancer, are characterized by inflammation and elevated serum ferritin (SF). However, the causal-relationship remains unclear. This study used primary rat hepatic stellate cells (HSC) as a model to investigate effects of physiological SF concentrations (10, 100 and 1000 pM) because HSCs play a central role in the development and progression of liver fibrosis. Physiological concentrations of SF, either horse SF or human serum, induced pro-inflammatory cytokine $IL1{\beta}$, IL6 and $TNF{\alpha}$ secretion in rat activated HSCs (all p<0.05). By contrast, treatment did not alter activation marker ${\alpha}SMA$ expression. The presence of SF markedly enhanced expression of Grp78 mRNA (p<0.01). Furthermore, transient knock down of Grp78 by endotoxin EGF-SubA abolished SF-induced $IL1{\beta}$ and $TNF{\alpha}$ secretion in activated HSCs (all p<0.05). In conclusion, our results showed that at physiological concentrations SF functions as a pro-inflammatory mediator in primary rat HSCs. We also provide a molecular basis for the action of SF and identified Grp78-associated ER stress pathways as a novel potential therapeutic target for resolution of fibrosis and possible prevention of liver cancer.

• Applied Microscopy
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• v.41 no.1
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• pp.69-73
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• 2011

High-voltage electron microscope (HVEM) has higher resolution and penetration power than conventional transmission electron microscope that could be load thick specimen. Some researchers have taken this advantage of HVEM to explore 3-dimensional configuration of the biological structures including tissue and cells. Whole mount preparations has been employed to study some cell lines and primary culture cells. In this study, we would like to introduce useful whole mount preparation method for neuronal studies. The plastic coverslips were punched, covered by formvar membrane and coated with carbon. The neurons obtained embryonic 18 rat hippocampus were seeded on the prepared cover slip. The coverslips were fixed, dried in freeze drier and kept in a descicator until HVEM observation. We could observe detailed neuronal structures such as soma, dendrite and spine under HVEM without conventional thin section and heavy metal stain. The anaglyphic image based on stereo paired image ($-8^{\circ},+8^{\circ}$) provides three dimensional perception of the neuronal dendrites and their spines. This method could be applied to sophisticated analysis of dendritic spine under the various experimental conditions.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2019.11a
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• pp.249-251
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• 2019

In the ongoing standardization of Versatile Video Coding (VVC), DCT-2, DST-7 and DCT-8 are designated as the vital primary transform kernels. Due to the effectiveness of DST-4 and DCT-4 in smaller resolution sequences, DST-4 and DCT-4 transform kernel can also be used as the replacement of the DST-7 and DCT-8 transform kernel respectively. While storing all of those transform kernels, ROM memory storage is considered as the major issue. So, to deal with this scenario, a unified DST-3 based transform kernel derivation method is proposed in this paper. The transform kernels used in this paper is DCT-2, DST-4 and DCT-4 transform kernels. The proposed ROM memory required to store the matrix elements is 1368 bytes each of 8-bit precision.

• Proceedings of the KSRS Conference
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• 1999.11a
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• pp.54-59
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• 1999

The KITSAT-3, launched on May 26th of 1999, is equiped with a high-resolution earth-watch sensor that has spectral bands similar to that of the SPOT. In this paper, the primary discussion is on Investigation of possible application of images acquired from this sensor The secondary discussion is on the comparison of the images with those of Landsat TM and SPOT.

• Proceedings of the KSRS Conference
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• 1999.11a
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• pp.135-139
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• 1999

Wind velocity is one of the primary variables for describing atmospheric state from GMS-5. And its accurate depiction is essential for operational weather forecasting and for initialization of NWP(Numerical Weather Prediction) models. The aim of this research is to incorporate imagery from other available spectral channels and examine the error characteristics of winds derived from these images. Multi spectral imagery from GMS-5 was used for this purpose and applied to Korean region with together BoM(Bureau of Meteorology). The derivation of wind velocity estimates from low and high resolution visible, split window infrared, and water vapor images, resulted in improvements in the amount and quality of wind data available for forecasting.

• Proceedings of the KSRS Conference
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• 1999.11a
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• pp.390-395
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• 1999

Ocean Scanning Multispectral Imager (OSMI) is a payload on the Korean Multi-purpose SATellite (KOMPSAT) to perform worldwide ocean color monitoring for the study of biological oceanography KOMPSAT will be launched in the middle of November this year. The radiometric performance of OSMI is analyzed for various gain settings in the viewpoint of the instrument developer for OSMI calibration and application based on its ground performance measurement data for 8 primary spectral bands of OSMI. The radiometric response linearity and dynamic range are analyzed for the image radiometric calibration and the estimation of OSMI image quality for the ocean remote sensing area. The dynamic range is compared with the nominal input radiance for the ocean and the land. The noise equivalent radiance (NER) corresponding to the instrument radiometric noise is compared with the radiometric resolution of signal digitization (1-count equivalent radiance). The best gain setting of OSMI for ocean monitoring is recommended. This analysis is considered to be useful for the OSMI mission and operation planning, the OSMI image data calibration, and users' understanding about OSMI image quality.

• Journal of Environmental Science International
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• v.7 no.6
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• pp.817-825
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• 1998

A three-dimensional ecosystem model is applied to the Suyoung Bay, located at the southeastern part of Korea, to study of the material distribution in the time scale of several tens days. The model has included of the DIN(Dissolved Inorganic Nitrogen), DIP(Dissolved Inorganic Phosphate), phytoplankton, zooplankton and detritus, and also was coupled with the physical processes. The spatial distribution of chlorophyll-a and primary productivity in the model is determined by the physical and chemical-biological parameters. The horizontal distributions of the DIN, DIP and chlorophyll-a are decreased from the coast to the off-shore, though the nutrients show some more complicated pattern than the chlorophyll-a. The nutrient contents in the off-shore are low, and thus a relatively low productivity(chlorophyll-a) are presented. On the whole, the distribution of the results of model are smoother than the observed ones and some small scale variation in the observed data cannot be reproduced by the model due to the resolution limits of model. However, the basic pattern and the quantitavities has been reproduced by the model well.

• Proceedings of the KIEE Conference
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• 2000.11c
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• pp.449-451
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• 2000

Crosstalk is the primary cause of image distortion in active matrix liquid crystal displays (AMLCD). Crosstalk produces voltage errors that limit gray scale fidelity and consequently, degrades display resolution, contrast ratio, color fidelity, and image quality. In this study, crosstalk phenomena of some methods to compensate level shift voltages has been simulated. This will be contributed to find the way to design the excellent image quality of the TFT-LCDs.