• Journal of Veterinary Science
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• v.23 no.6
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• pp.89.1-89.7
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• 2022

It is challenging to diagnose metastatic tumors whose cellular morphology is different from the primary. We characterized canine primary pulmonary adenocarcinoma (PAC) and its xenografted tumors by histological and immunohistochemical analyses for critical diagnostic and cancer stem cell (CSC) markers. To generate a tumor xenograft model, we subsequently transplanted the tissue pieces from the PAC into athymic nude mice. Immunohistochemical examination was performed for diagnostic (TTF-1, Napsin A, and SP-A) and CSC markers (CD44 and CD133). The use of CSC markers together with diagnostic markers can improve the detection and diagnosis of canine primary and metastatic adenocarcinomas.

• The Journal of the Korean dental association
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• v.50 no.6
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• pp.312-321
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• 2012

Permanent canine are very important teeth in point of function as well as esthetic. Therefore impaction of canines is a frequently encountered clinical problems. The incidence of impaction ranges between 1-3%. The cause of canine impaction can be result of ectopic position of tooth germ, defect of dental follicle, early loss or delayed exfoliation primary canine, space problem, supernumarary teeth, cyst, odontoma, Impaction frequently involves further complication such as root resorption of adjacent teeth, cyst formation and migration of the neighboring teeth. Various treatment modalities include extraction of primary canine, surgical opening and orthodontic traction, autotransplantation, surgical extraction of impacted canine.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.1
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• pp.87-101
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• 2015

The premature loss of the mandibular primary canine is relatively frequent and a sign of the upcoming space problems in the transitional period. This situation is caused by the permanent lateral incisor resorbing the root of the primary canine during its eruption. Bilateral loss of primary canines in a crowded arch leads to the lingual tipping of the permanent incisors, with the consequent reduction in the arch perimeter and increase in overbite. When the loss of a primary canine is unilateral, tipping of the adjacent incisors occurs toward the space, resulting in midline deviation. In these situations, treatment possibilities, such as extraction of the antimeric tooth or placement of a passive lingual arch, can be applied; although there are some controversies concerning this. Most space problems with less than 4 mm can be resolved through preservation of the leeway space using sequential disking of the primary teeth and a passive lingual arch, regaining space or limited arch expansion in the late mixed dentition. In cases with 4~6 mm of space problems, arch expansion (A-P or transverse) can be applied. Space problems with more than 6 mm should be treated through diagnosis and treatment planning. Most of these cases will require extraction of permanent teeth including serial extraction (guidance of eruption).

• Journal of the korean academy of Pediatric Dentistry
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• v.7 no.1
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• pp.53-61
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• 1980

The purpose of this study was to statistically evaluate the spacing of primary dentition according to whether or not a space existed and measurement of amount of space in 205 children (male 114, female 91) from 2 to 6 years of age. The results were as follows; 1. In the incidence of interdental space on each region, spacing between the primary lateral incisors and primary canine in maxilla and between the primary canine and 1st primary molar in mandible showed the highest percentage, on the other hand, spacing between the 1st and 2nd primary molars in both jaw showed the lowest percentage. 2. In the kinds of interdental space, the state of primate space and other space together showed the highest percentage, and in the degree of spacing, $S_2$ showed the highest percentage in both jaw. 3. In the incidence of primate space, maxillary primate space showed higher percentage than mandibular primate space in bilateral case. 4. In the type of arch form, spaced arch showed higher percentage than closed arch and about the half of closed arch showed crowding. 5. In both Jaw, available space showed incisor segments, canine segments, and premolar segments in order of amount, and there were not statistically significant differences of sex or jaws in the amount of available space.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.4
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• pp.468-480
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• 2022

The purpose of this study was to evaluate the effect of interceptive primary canine extraction in palatally and buccally displaced maxillary permanent canines, and to analyze the clinical and radiographic factors affecting the treatment outcome. 97 maxillary permanent canines from 86 patients whose maxillary permanent canine were in the mesio-occlusal directions and overlapped with the roots of the adjacent teeth were analyzed. In 64 of 97 (66.0%) maxillary permanent canines, the displaced crown was completely deviated from the adjacent lateral incisor root only by extraction of the primary canine. Not only the characteristics of maxillary permanent canines such as bucco-palatal displacement direction, horizontal and vertical position of the crown tip, and presence of apical closure, but also periapical rarefaction on the primary canine and peg-shaped adjacent lateral incisor significantly affected the treatment outcome.

• The korean journal of orthodontics
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• v.48 no.3
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• pp.200-211
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• 2018

The aim of this systematic review was to evaluate the effectiveness and complications of corticotomy and piezocision in canine retraction. Five electronic databases (PubMed, SCOPUS, Web of Science, Embase, and CENTRAL) were searched for articles published up to July 2017. The databases were searched for randomized control trials (RCTs), with a split-mouth design, using either corticotomy or piezocision. The primary outcome reported for canine retraction was either the amount of tooth movement, rate of tooth movement, or treatment time. The secondary outcome was complications. The selection process was based on the PRISMA guidelines. A risk of bias assessment was also performed. Our search retrieved 530 abstracts. However, only five RCTs were finally included. Corticotomy showed a more significant (i.e., 2 to 4 times faster) increase in the rate of tooth movement than did the conventional method. For piezocision, both accumulative tooth movement and rate of tooth movement were twice faster than those of the conventional method. Corticotomy (with a flap design avoiding marginal bone incision) or flapless piezocision procedures were not detrimental to periodontal health. Nevertheless, piezocision resulted in higher levels of patient satisfaction. The main limitation of this study was the limited number of primary research publications on both techniques. For canine retraction into the immediate premolar extraction site, the rate of canine movement after piezocision was almost comparable to that of corticotomy with only buccal flap elevation.

• The korean journal of orthodontics
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• v.23 no.2 s.41
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• pp.165-177
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• 1993

Upper canine is important because it protects and maintains the stability of the dental arch and also, joins the anterior with the posterior teeth. The incidence of impaction of upper canine is the second most frequent next to the third molar because it takes a long period of time to develop, and has a complicated path of eruption, and erupts lately. After the age of 10, clinical and radioglaphic examination can be used in revealing the possibility of impaction and efforts should be put to reduce the side effects. To prevent impaction, selective extraction of primary canine at the age of 8 to 9 could be considered and prolonged retention of primary canine in oral cavity should be avoided at this time. Once the impaction is iden, the first stage of the treatment is to lcocalize the lesion by radiographic examination and According to the severity, orthodontic traction or autotransplantation should be considered and comprehensive diagnosis and treatment plan of malocclusion should be established. Generally, labial impaction is due to arch length discrepancy and palatal impaction is due to malposition or morphologic pathosis of lateral incisors rather than arch length discrepancy. In surgical procedure, peridontal problems should be considered and the minimum amount of bone and soft tissue should be reduced and direct bonding method of many attachment methods should be recommended. Especially in traction of labially impacted canine, it should be guided to erupt through the keratinized zone and proper forced magnitude should be applied. The importance of periodontal condition should always be in mind following the patient education to mintain the good oral hygiene at each stage of treatment. Properly managed impacted canine can provide function and esthetic by proper diagnosis and treatment if extraction of canine is not indicated.

• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.4
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• pp.946-953
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• 1996

The occlusal patterns and profiles of the primary dentition were studied by oral examination from 3 to 6 year-old children (200 boys, 200 girls) in Kwangju city. The results were as follows; 1. In sagittal primary canine relationship, Class 1 pattern (74.75 %) was prevalent. 2. In sagittal primary molar relationship, Class 1 pattern (56 %) was prevalent. 3. In profile view, straight profile (77%) was prevalent. 4. In comparison of relationship between primary canine relationship, primary molar relationship and profile, Class 1 pattern-Class 1 pattern-Straight profile (43.14 %) was prevalent.

• The Journal of the Korean dental association
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• v.11 no.5
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• pp.313-316
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• 1973

970 children visited attached hospital, S.N.U, were taken orthopantomograph. Of those children, there were 14 patients who have primary fused teeth. The author observed those cases and got following results. 1) Incidence of primary fused teeth was higher in female. 2) In the order of frequency, fused teeth of mandibular right primary lateral incisor and canine were 9 and that of mandibular left primary lateral incisor and canine were 4, and there was only one case in maxillary. 3) 13 cases showed the congenital absence of lateral incisor of the corresponding permanent teeth. 4) Incidence of fused teeth was 1.44%.

• Journal of Veterinary Science
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• v.24 no.4
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• pp.57.1-57.8
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• 2023

Siewert-Kartagener's syndrome, a type of primary ciliary dyskinesia, is a complex disease comprising situs inversus, rhinosinusitis, and bronchiectasis. Situs inversus totalis is a condition in which all organs in the thoracic and abdominal cavities are reversed. Furthermore, primary ciliary dyskinesia, an autosomal genetic disease, may coexist with situs inversus totalis. Reports on Siewert-Kartagener's syndrome in veterinary medicine are limited. We report a rare case of primary ciliary dyskinesia with Siewert-Kartagener's syndrome in a dog, concurrently infected with canine distemper virus and type-2 adenovirus. This case highlights that situs inversus totalis can cause primary ciliary dyskinesia, and concurrent infections are possible.