• Title/Summary/Keyword: Prevention stage

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Prognostic Significance of the Mucin Component in Stage III Rectal Carcinoma Patients

  • Wang, Meng;Zhang, Yuan-Chuan;Yang, Xu-Yang;Wang, Zi-Qiang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8101-8105
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    • 2014
  • Background: Although mucinous adenocarcinoma has been recognized for a long time, whether it is associated with a poorer prognosis in colorectal cancer patients is still controversial. Many studies put emphasis on mucinous adenocarcinoma containing mucin component ${\geq}50%$. Only a few studies have analyzed cases with a mucin component <50%. Objectives: This study aimed to analyze the prognostic value of different mucin component proportions in patients with stage III rectal cancer. Materials and Methods: Clinical, pathological and follow-up data of 136 patients with the stage III rectal cancer were collected. Every variable was analyzed by univariate analysis, then multivariate analysis and survival analysis were further performed. Results: Univariate analysis showed pathologic T stage, lymphovascular invasion, and histological subtype were statistically significant for DFS. Pathologic T stage was significant for OS. Histological subtype and lymphovascular invasion were independent prognostic factors in multivariate analysis for DFS, and histological subtype was the only independent prognostic factor for OS. Survival curves showed the survival time of mucinous adenocarcinoma (MUC) was shorter than non-MUC (adenocarcinomas with a mucin component <50% and without mucin component). Conclusions: Histological subtype (tumor with different mucin component) was an independent prognostic factor for both DFS and OS. Patients with MUC had a worse prognosis than their non-MUC counterparts with stage III rectal carcinoma.

Design of Direct-Current Fuzzy Controller for Mitigating Commutation Failure in HVDC System

  • Gao, Benfeng;Yuan, Kewei;Dong, Peiyi;Luo, Chao;Zhao, Shuqiang
    • Journal of Electrical Engineering and Technology
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    • v.13 no.4
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    • pp.1450-1458
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    • 2018
  • Commutation failures can deteriorate the availability of high-voltage direct current (HVDC) links and may lead to outage of the HVDC system. Most commutation failures are caused by voltage reduction due to ac system faults on inverter side. The commutation failure process can be divided into two stages. The first stage, from the occurrence to the clearing of faults, is called 'Deterioration Stage'. The second stage, from the faults clearing to restoring the power system stability, is called 'Recovery Stage'. Based on the analysis of the commutation failure process, this paper proposes a direct-current fuzzy controller including prevention and recovery controller. The prevention controller reduces the direct current to prevent Commutation failures in the 'Deterioration Stage' according to the variation of ac voltage. The recovery controller magnifies the direct current to speed up the recovery of power system in the 'Recovery Stage', based on the recovery of direct voltage. The validity of this proposed fuzzy controller is further proved by simulation with CIGRE HVDC benchmark model in PSCAD/EMTDC. The results show the commutation failures can be mitigated by the proposed direct-current fuzzy controller.

Development and Evaluation of a Small Group-based Cardiocerebrovascular Disease Prevention Education Program for Male Bus Drivers (남성 운전직 근로자를 위한 소그룹기반 심뇌혈관질환 예방교육 프로그램의 개발 및 효과)

  • Kim, Eun-Young;Hwang, Seon-Young
    • Journal of Korean Academy of Nursing
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    • v.42 no.3
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    • pp.322-332
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    • 2012
  • Purpose: This study was conducted to examine effects of a small group-based cardiocerebrovascular disease (CVD) prevention education program on knowledge, stage of change and health behavior among male bus drivers with CVD risk factors. Methods: A non-equivalent control group pretest-posttest design was used. Participants were 68 male bus drivers recruited from two urban bus companies. Participants from the two groups were selected by matching age, education and risk factors. Experimental group (n=34) received a small group-based CVD prevention education program 8 times over 6 weeks and 3 times through telephone interviews at 2-week intervals. Data were collected between December, 2010 and March, 2011, and were analyzed using chi-square test, t-test, and repeated measure analysis of variance with SPSS/Win18.0. Results: Experimental group showed significantly higher scores in CVD prevention knowledge (p<.001) and health behavior (p<.001) at 6 and 12 weeks after intervention. Participants in pre-contemplation and contemplation stages made progress to contemplation and action. This was significantly better at 6 and 12 weeks after intervention (p<.001). Conclusion: Results suggest that small group-based education programs for CVD prevention are effective in increasing knowledge, stage of change, and health behavior to prevent CVD among male bus drivers with CVD risk.

Factors Influencing University Students' Infection Prevention Behaviors Compliance in the Early Stage of COVID-19 (코로나19 초기 유행 시기에서 대학생의 감염예방행위 수행도에 미치는 영향 요인)

  • Lee, Hyunju;Park, Jinhee;Kim, Jihye;Kang, Purum
    • Journal of the Korean Society of School Health
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    • v.34 no.3
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    • pp.190-199
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    • 2021
  • Purpose: The study aims to identify factors that influence university students' compliance with infection prevention behaviors in the early stage of COVID-19. Methods: A survey was conducted online from July 29 to August 2, 2020, involving 261 students enrolled in general universities. Frequency analysis, descriptive statistics, t-test, ANOVA, correlation, and multiple regression analysis were carried out on the collected data using SPSS 24.0. Results: The average score of university students' risk perception of COVID-19 was 3.80, while the average score of health risk communication was 3.92. The average score of efficacy beliefs was 4.42 and the average score of practicing infection prevention behaviors was 4.54. Factors influencing the level of infection prevention behaviors were efficacy of preventive behaviors (β=.48 p<.001), health risk communication (β=.16, p=.003), subjective health status (β=.12, p=.015), and the type of college (β=.11, p=.041). Conclusion: In order to improve college students' infection prevention behaviors related to COVID-19, consideration should be given to providing interventions that focus on accurate knowledge and dissemination of accurate information about new infectious diseases and effectiveness of infection preventive behaviors.

Single Institution Experience of Thymic Tumor Treatment and Survival in Egypt

  • Darwish, Dalia
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.771-774
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    • 2016
  • Thymic tumors are the most common tumors in the anterior mediastinum. Total resection is the main treatment and predictor of longer survival. Adjuvant radiotherapy alone or in combination with chemotherapy is recommended with incomplete excision or advanced disease. Thirty seven patients with thymic tumors were included in this retrospective study from January 2001 till December 2012. They were studied regarding age, sex, performance status, tumor size and invasion, stage, pathology, treatment given, overall and progression free survival. Myasthenia gravis was present in 18.1% of the patients. Masaoka stage III was diagnosed in 40.5% of the cases followed by stage II in 24.3% and the other stages with lower percentages. Pathology type B3 was the most frequent followed by B2 and B1 with percentages of 27, 24.3 and 21.7 respectively. Complete resection was conducted in 11 cases (29.75%). Partial resection or debulking was done in 15 (40.5%) and a biopsy was taken in 11 cases (29.8%) Adjuvant chemotherapy was given to 14 patients (37.8%) and neoadjuvant to 13 (35.2%). Adjuvant radiotherapy was given to 17 patients (46%) and neoadjuvant to 14 (37.8%). The 5-year overall survival by was 83% for stage I, 71% for stage II, 60% for stage III, and 44% for stage IV (p=0.0426). Five year progression free survival was 71% for stage I, 62% stage II, 42% stage III, and 37% for stage IV (p=0.0532). In conclusion with the rare thymic tumors early stage and complete resection have the highest impact on overall and progression free survival.

Effect of Hydronephrosis on Survival in Advanced Stage Cervical Cancer

  • Goklu, Mehmet Rifat;Seckin, Kerem Doga;Togrul, Cihan;Goklu, Yasemin;Tahaoglu, Ali Emre;Oz, Murat;Ertas, Ibrahim Egemen
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.10
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    • pp.4219-4222
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    • 2015
  • Background: Hydronephrosis is frequently encountered in advanced stage cervical cancers, and may be associated with mortality. In the present study, we aimed to demonstrate the effect of hydronephrosis on survival in patients with inoperable advanced stage cervical cancer. Materials and Methods: The study data were acquired by retrospective analysis of the patient records belonging to 165 women with FIGO (International Federation of Gynecology and Obstetrics) stage-IIIB or more advanced cervical cancer, which were not surgical candidates. Parameters including patient age, pathological diagnosis, disease stage, pelvic sidewall extension, presence of hydronephrosis and administration of chemoradiation were analyzed. Further, the effects of these variables on survival were assessed. P values less than 0.05 were considered statistically significant. Results: The distribution of the study patients according to disease stage was as follows: 131 (79.4%) had stage-IIIB, 18 (10.9%) had stage-IVB and 16 (% 9.7) patients had stage-IVA disease. Hydronephrosis was not evident in 91 (55.2%) of these patients, whereas 41 (24.8%) had unilateral and 33 (20%) patients had bilateral hydronephrosis. When compared to mean survival in patients who did not have hydronephrosis, survival was significantly shortened in patients who had bilateral and unilateral hydronephrosis (p<0.05). There was no significant survival difference between patients with unilateral and bilateral hydronephrosis (p>0.05). Although patient age, pathological type, pelvic involvement, and chemotherapy treatment rates were similar (p>0.05), radiotherapy requirement rate and disease stage were significantly different among the study groups (p<0.05). Conclusions: Hydronephrosis was found to be a significant predictor of poor survival in patients with advanced stage cervical cancer, irrespective of unilateral or bilateral involvement.While waiting for future studies with larger sample sizes, we believe that the FIGO stages in advanced cervical cancer could further be stratified into subgroups according to presence or absence of hydronephrosis.

Colorectal Cancer Concealment Predicts a Poor Survival: A Retrospective Study

  • Li, Xiao-Pan;Xie, Zhen-Yu;Fu, Yi-Fei;Yang, Chen;Hao, Li-Peng;Yang, Li-Ming;Zhang, Mei-Yu;Li, Xiao-Li;Feng, Li-Li;Yan, Bei;Sun, Qiao
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4157-4160
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    • 2013
  • Objectives: Understanding the situation of cancer awareness which doctors give to patients might lead to prognostic prediction in cases of of colorectal cancer (CRC). Methods: Subsets of 10,779 CRC patients were used to screen the risk factors from the Cancer Registry in Pudong New Area in cancer awareness, age, TNM stage, and gender. Survival of the patients was calculated by the Kaplan-Meier method and assessed by Cox regression analysis. The views of cancer awareness in doctors and patients were surveyed by telephone or household. Results: After a median observation time of 1,616 days (ranging from 0 to 4,083 days) of 10,779 available patients, 2,596 of the 4,561 patients with cancer awareness survived, whereas 2,258 of the 5,469 patients without cancer awareness and 406 of the 749 patients without information on cancer awareness died of the disease. All-cause and cancer-specific survival were poorer for the patients without cancer awareness than those with (P < 0.001 for each, log-rank test). Cox multivariate regression analysis showed that cancer concealment cases had significantly lower cancer-specific survival (hazard ratio (HR) = 1.299; 95 % confidence interval (CI): 1.200-1.407)and all-cause survival (HR = 1.324; 95 % CI: 1.227-1.428). Furthermore, attitudes of cancer awareness between doctors and patients were significantly different (P < 0.001). Conclusion: Cancer concealment, not only late-stage tumor and age, is associated with a poor survival of CRC patients.

Skin Cancer Concerns in People of Color: Risk Factors and Prevention

  • Gupta, Alpana K;Bharadwaj, Mausumi;Mehrotra, Ravi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.12
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    • pp.5257-5264
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    • 2016
  • Background: Though people of color (POC) are less likely to become afflicted with skin cancer, they are much more likely to die from it due to delay in detection or presentation. Very often, skin cancer is diagnosed at a more advanced stage in POC, making treatment difficult.The purpose of this research was to improve awareness regarding skin cancers in people of color by providing recommendations to clinicians and the general public for early detection and photo protection preventive measures. Methods: Data on different types of skin cancers were presented to POC. Due to limited research, there are few resources providing insights for evaluating darkly pigmented lesions in POC. Diagnostic features for different types of skin cancers were recorded and various possible risk factors were considered. Results: This study provided directions for the prevention and early detection of skin cancer in POC based on a comprehensive review of available data. Conclusions: The increased morbidity and mortality rate associated with skin cancer in POC is due to lack of awareness, diagnosis at a more advanced stage and socioeconomic barriers hindering access to care. Raising public health concerns for skin cancer prevention strategies for all people, regardless of ethnic background and socioeconomic status, is the key to timely diagnosis and treatment.

A Study on the Fire Protection System in the Stage (공연장의 소방시설 설치기준의 개선방안에 관한 연구)

  • 장상태;이영재
    • Fire Science and Engineering
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    • v.13 no.4
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    • pp.13-19
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    • 1999
  • Currently, conventional fire prevention facility installation standard is based on the use and size of the domestic theaters. In the study, theaters with 1,900 seats were examined to suggest a suitable method to adapt a better fire preventing system. The proposed systems are as follow. - 100% of backup pressed-water outlet device, considering waterproof pressure for fire prevention facility at the top floor. - The supplement of the side wall type header and a large caliber outlet header for stage open sprinkler. - Subdividing a installation rule for special detector and implementing the latestdetector. - Installation of fire curtain for dividing stage area and auditorium area, and also the method of installation of fire curtain.

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The Marital Relationship Enhancement Program and Its Effects for Couples in the Early Marriage Stage (결혼초기 부부관계향상 프로그램의 효과검증 -PREP(Prevention and Relationship Enhancement Program)을 중심으로-)

  • Yu Eun-Hee;Kim Deuk-Sung
    • Journal of Families and Better Life
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    • v.23 no.1 s.73
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    • pp.1-18
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    • 2005
  • The purpose of this study was to construct the Marital Relationship Enhancement Program based on PREP(Prevention and Relationship Enhancement Program), and to examine the effect of it for couples in the early marriage stage. To perform this program, six session of time-limited(two hour) were carried out experimental group. and subjects were assigned to experimental group(N=6 couples) and control group(N=6 couples). Scales of PREPARE II (PREmarital Personal And Relationship Evaluation), Couple Communication Scales and Commitment Scales were used as pre-post-follow instruments of this study. Major finding were as follows : 1. Marital Relationship Enhancement Program for couples in the early marriage stage has meaningful consequences for the improvement of participants' couple relationship. 2. Marital Relationship Enhancement Program had meaningful consequence for the improvement of participants' realistic expectation of marriage, communication and conflict resolution skills and leisure activities. These positive effects maintained at follow-up. However, it hadn't meaningful consequence for the improvement of participants' marital commitment. 3. Marital Relationship Enhancement Program had also meaningful consequence for the improvement of the wives' realistic expectation of marriage, communication and conflict resolution skills and leisure activities, of the husbands' communication and conflict resolution skills.