• Title/Summary/Keyword: Prevention Control

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Randomized-Control Screening Trials to Lower Gall Bladder Cancer Mortality in High Risk Populations

  • Krishnatreya, Manigreeva;Kataki, Amal Chandra
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2325-2327
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    • 2016
  • Gall bladder cancer is generally fatal. The high morbidity and mortality due to gall bladder cancer exerts a significant impact on efforts towards cancer control in high risk populations of the World and a rationale program for control of gall bladder cancer mortality has remained as an unmet need in these populations. Currently there are no effective strategies for controlling gall bladder cancer mortality. This mini review is to highlight the need and feasibility for secondary prevention of gall bladder cancer by screening in high risk populations. A way forward is to assess the role of secondary prevention of gall bladder cancers by conducting randomized-controlled screening trials in high risk populations.

Phase II Study on EANI Combined with Hydrochloride Palonosetron for Prevention of Chemotherapy-induced Nausea and Vomiting Following Highly Emetogenic Chemotherapy

  • Xiao, Yang;Liu, Jun;Liu, Yang-Chen;Huang, Xin-En;Guo, Jian-Xong;Wei, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3951-3954
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    • 2014
  • Objective: To investigate the electronic anti-nausea instrument (EANI) combined with hydrochloride palonosetron for prevention of chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy. Methods: Patients who received highly emetogenic chemotherapy were randomly assigned to a treatment group (60 patients) treated with EANI combined with hydrochloride palonosetron, and control group (also 60 patients) given only hydrochloride palonosetron. Chemotherapy related nausea and vomiting were observed and recorded in both groups of patients from the start till the end of chemotherapy. Results: Complete control rates of vomiting in treatment and control group were 40%, and 35%, respectively, without any statistical ly significant difference (p>0.05); however the response rates are 95.0%, 78.3%, respectively, with statistical difference (p<0.05). Complete control rates of nausea in treatment and control group were 36.7%, 30%, respectively, without statistical difference (p>0.05); but the response rates are 90.0%, 76.7%, respectively, with statistical difference (p<0.05). Conclusion: EANI combined with hydrochloride palonosetron for prevention of nausea and vomiting induced by chemotherapy could be more effective than hydrochloride palonosetron alone, and can be recommended for use in prevention and treatment of chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy.

Refining and Validating a Two-stage and Web-based Cancer Risk Assessment Tool for Village Doctors in China

  • Shen, Xing-Rong;Chai, Jing;Feng, Rui;Liu, Tong-Zhu;Tong, Gui-Xian;Cheng, Jing;Li, Kai-Chun;Xie, Shao-Yu;Shi, Yong;Wang, De-Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10683-10690
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    • 2015
  • The big gap between efficacy of population level prevention and expectations due to heterogeneity and complexity of cancer etiologic factors calls for selective yet personalized interventions based on effective risk assessment. This paper documents our research protocol aimed at refining and validating a two-stage and web-based cancer risk assessment tool, from a tentative one in use by an ongoing project, capable of identifying individuals at elevated risk for one or more types of the 80% leading cancers in rural China with adequate sensitivity and specificity and featuring low cost, easy application and cultural and technical sensitivity for farmers and village doctors. The protocol adopted a modified population-based case control design using 72, 000 non-patients as controls, 2, 200 cancer patients as cases, and another 600 patients as cases for external validation. Factors taken into account comprised 8 domains including diet and nutrition, risk behaviors, family history, precancerous diseases, related medical procedures, exposure to environment hazards, mood and feelings, physical activities and anthropologic and biologic factors. Modeling stresses explored various methodologies like empirical analysis, logistic regression, neuro-network analysis, decision theory and both internal and external validation using concordance statistics, predictive values, etc..

Children with COVID-19 after Reopening of Schools, South Korea

  • Kim, Eun Young;Ryu, Boyeong;Kim, Eun Kyoung;Park, Young-Joon;Choe, Young June;Park, Hye Kyung;Jeong, Eun Kyeong
    • Pediatric Infection and Vaccine
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    • v.27 no.3
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    • pp.180-183
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    • 2020
  • Purpose: To describe pediatric coronavirus disease 2019 (COVID-19) cases after the reopening of schools in the Republic of Korea and their transmission routes. Methods: All case report forms and epidemiologic investigation forms for children aged 3-18 years reported as COVID-19 cases to the National Notifiable Disease Surveillance System from May 1 to July 12, 2020, were reviewed. Results: After the schools were reopened in May 2020, a total of 127 pediatric COVID-19 cases were confirmed until July 12. Of these, 59 children (46%) were exposed to severe acute respiratory syndrome coronavirus 2 through family and relatives, followed by 18 children (14%) through cram schools or private lessons, 8 children (6%) through multi-use facilities, and 3 children (2%) through school. Conclusions: The present data do not suggest an increased risk of COVID-19 transmission in the context of stringent school-based infection prevention measures introduced across the country.

Sales Control Systems and Behavioral Responses: Mediating Role of Regulatory Focus and Moderating Role of P-O Fit

  • Yoo, Jaewon
    • Asia Marketing Journal
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    • v.17 no.1
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    • pp.123-148
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    • 2015
  • Built on regulatory focus theory, this article develops a research model proposing the relationship between management controls (outcome, activity and capability), sales employees' prevention and promotion focus and their behavioral responses (feedback seeking from different sources and relationship investment). The model also suggests that salesperson perceived organizational fit (P-O fit) contributes by influencing the situational self-regulatory mechanism based on regulatory fit theory. To analyze the data, a structural equation model procedure using LISREL 8.5 was employed. To access the potential common method bias, the MV" marker method was applied using a scale theoretically unrelated to at least one scale in the analysis as the MV marker. The results showed that the greater the salesperson's perceived activity control system, the greater the extent of employee prevention focus. The findings also showed that output control and capability control system are positively related to the promotion focus of salespeople. Salespeople's prevention focus relates negatively to the relational investment and positively to organization feedback seeking. The results indicate that salespeople who have promotion focus exhibit the predicted positive influence on their relationship investment. A significant contribution of this research framework is suggesting salesperson regulatory focus as a mediator and its' effects on different types of sales-related behaviors. The author suggests that the motivational orientations of salespeople play key roles in shaping feedback seeking behaviors from different sources; broadly, that employees with a promotion focus will be more sensitive to customers' feedback, and employees with a prevention focus will seek more feedback from the organization. Furthermore, salespeople with a promotion focus will invest more resources to build relationships with customers than salespeople with a prevention focus. This research also explains the moderating role of person-organization fit on the effect of salespeople's regulatory focus and behavioral responses based on regulatory fit theory

Time Trends of Nasopharyngeal Carcinoma in Urban Guangzhou over a 12-Year Period (2000-2011): Declines in Both Incidence and Mortality

  • Li, Ke;Lin, Guo-Zhen;Shen, Ji-Chuan;Zhou, Qin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9899-9903
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    • 2014
  • Nasopharyngeal carcinoma (NPC) is an uncommon disease in most countries but occurs with much greater frequency in southern China. This study aimed to examine the secular trends of NPC in urban Guangzhou over the time period of 2000-2011 using data from the Guangzhou Cancer Registry. Age-adjusted annual incidence rates of NPC were calculated by the direct method using the WHO World Standard Population (1960) as the reference. The average annual percentage change (AAPC) was used as an estimate of the trend. A total of 7,532 new cases of NPC and 3,449 related deaths were registered. In both genders, the peak incidence occurred in the 50- to 59-year age group, and this age distribution pattern remained similar throughout. The AAPC in NPC incidence rates was -3.26% (95% CI: -5.4%--1.1) for males and -5.74% (95% CI: -8.9%--2.5) for females, resulting in a total decrease of 39.3% (from 22.14 to 13.44 per 100,000 population) for males and 48.6% (from 10.1 to 5.18 per 100,000 population) for females over this 12-year period. The AAPCs in NPC mortality rates were -4.62% (95%CI: -3.5%--5.7) for males and -6.75% (95% CI: -5.2%--8.3) for females, resulting in a total decrease of -46.1% (from 12.1 to 6.54 per 100,000 population) for males and 51.7% (from 4.14 to 2.00 per 100,000 population) for females. The age-adjusted incidence and mortality rates of NPC declined during 2000-2011 in urban Guangzhou but remained high. Future efforts to improve prevention, early detection and treatment strategies are needed.

Effects of Delirium Prevention Program in Patients after Hip Joint Surgery (고관절 수술환자에게 적용한 섬망 예방프로그램의 효과)

  • SaGong, Eun Mi;Kim, Sook Young
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.134-144
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    • 2018
  • The purpose of this study was to examine the effects of delirium prevention program in patients after hip joint surgey. A non equivalent control group post-test only design was utilized. Sixty four patients aged 65 and older who admitted to a surgical intensive care unit after hip joint surgery were assigned to either a experimental group (n=33) or a control group (n=31). The experimental group was provided with delirium prevention program consisting of orientation intervention, activity intervention, physiological intervention, nutritional intervention, sleep intervention, environmental intervention. Data were analyzed using ${\chi}^2-test$ and independent t-test. The experimental group showed lower incidence of delirium than the control group(${\chi}^2=7.048$, p=.008). The experimental group showed lower ICU stay and length of hospitalization than the control group although the difference was not statistically significant. Findings indicate that the dilirium prevention program is effective in reducing incidence of delirium in patients after hip joint surgery and delirium prevention program is recommended as a guide for the prevention of delirium.

The Control System of a Robot Bed for Caring Pressure Ulcer

  • Kim, Jungae;Lee, Youngdae;Cho, Hyunkyung
    • International Journal of Advanced Culture Technology
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    • v.8 no.3
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    • pp.254-259
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    • 2020
  • The medical bed developed in this study is an electrically driven segmental keyboard. First describe the instrument of the segmental bed specially designed for pressure ulcer prevention, then the motor control system and pressure ulcer prevention operation of the bed. The main factor of pressure ulcer generation is displayed as body pressure x time, and when the keyboard falls, the body pressure becomes zero, and the pressure becomes higher than the threshold even if the body pressure is above the threshold, the pressure control algorithm has been developed. Therefore, using the proposed pressure control method, it has no particular ulcer occurred theoretically.

Development of Pine Wilt Disease (Bursaphelenchus Xylophilus) Prevention System (소나무재선충병 방제관제시스템 개발에 관한 연구)

  • Seo, Bong-Sang;Jeon, Hyeong-Seob;Kim, Jun-Beom;Cho, Gi-Sung
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2007.04a
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    • pp.283-287
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    • 2007
  • Pine Wilt Disease (Bursaphelenchus Xylophilus) has been attacked since 1988, then it becomes very serious problem of the all over the country. Government has been invested a lot of money to prevent but it is hard to survey the damaged area and ineffectively control the process of prevention. Therefore, this study is focused on development of Pine Wilt Disease (Bursaphelenchus Xylophilus) Prevention System using GIS and GPS through constructiong database of digital map, satellite imagery and attribute data and development component for desktop PC, internet and mobile system to realtime data transmission between project manager and field worker. Especially, we developed the mobile system that can transmit field conditions in realtime using GPS, GIS and CCD camera, the telecommunication control server that transmit received field condition data to web connecting module and system manager, the web system for end user to notify prevention details, the control system lot manager to recognize filed conditions and to control field workers and the wireless telecommunication module to connect in realtime between field and control center.

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The Development & Effect of an Tailored Falls Prevention Exercise for Older Adults (노인 낙상예방 맞춤운동의 개발 및 효과)

  • Gu, Mee-Ock;Jeon, Mi-Yang;Eun, Young
    • Journal of Korean Academy of Nursing
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    • v.36 no.2
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    • pp.341-352
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    • 2006
  • Purpose: This study was conducted to develop & to determine the effect of an tailored falls prevention exercise for older adults. Method: Subjects consisted of 59 older adults (experimental group : 29, control group : 30) living at nursing homes. Experimental group participated in tailored falls prevention exercise for 16 weeks(3 times a week, 50 min every session). Data were collected before the exercise, 16 weeks & 24 weeks after the beginning of exercise. Results: 1) the experimental group significantly improved the muscle strength of hip extensor & flexor, knee extensor & flexor, ankle dorsiflexor, & plantar flexor compared to the control group. 2) the experimental group significantly decreased the mean time for 10 times chair stand. 3) the experimental group significantly increased the standing time on one leg and the number of heel raise for 30 seconds compared to the control group. In addition more older adults in the experimental group completed the tandem stance & semi-tandem stance for 10 seconds than the control group. 4) The experimental group significantly decreased the mean time of 6m walk and the fall frequency compared to the control group. Conclusions: This results suggest that tailored falls prevention exercise for older adults can improve muscle strength, static & dynamic balance and decrease the fall frequency of older adults.