Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Time Trends of Nasopharyngeal Carcinoma in Urban Guangzhou over a 12-Year Period (2000-2011): Declines in Both Incidence and Mortality

  • Li, Ke (Guangzhou Center for Disease Control and Prevention) ;
  • Lin, Guo-Zhen (Guangzhou Center for Disease Control and Prevention) ;
  • Shen, Ji-Chuan (Guangzhou Center for Disease Control and Prevention) ;
  • Zhou, Qin (Guangzhou Center for Disease Control and Prevention)
  • Published : 2014.12.18
Download PDF
⟨ Previous Next ⟩

Abstract

Nasopharyngeal carcinoma (NPC) is an uncommon disease in most countries but occurs with much greater frequency in southern China. This study aimed to examine the secular trends of NPC in urban Guangzhou over the time period of 2000-2011 using data from the Guangzhou Cancer Registry. Age-adjusted annual incidence rates of NPC were calculated by the direct method using the WHO World Standard Population (1960) as the reference. The average annual percentage change (AAPC) was used as an estimate of the trend. A total of 7,532 new cases of NPC and 3,449 related deaths were registered. In both genders, the peak incidence occurred in the 50- to 59-year age group, and this age distribution pattern remained similar throughout. The AAPC in NPC incidence rates was -3.26% (95% CI: -5.4%--1.1) for males and -5.74% (95% CI: -8.9%--2.5) for females, resulting in a total decrease of 39.3% (from 22.14 to 13.44 per 100,000 population) for males and 48.6% (from 10.1 to 5.18 per 100,000 population) for females over this 12-year period. The AAPCs in NPC mortality rates were -4.62% (95%CI: -3.5%--5.7) for males and -6.75% (95% CI: -5.2%--8.3) for females, resulting in a total decrease of -46.1% (from 12.1 to 6.54 per 100,000 population) for males and 51.7% (from 4.14 to 2.00 per 100,000 population) for females. The age-adjusted incidence and mortality rates of NPC declined during 2000-2011 in urban Guangzhou but remained high. Future efforts to improve prevention, early detection and treatment strategies are needed.

Keywords

References

  1. Arnold M, Wildeman MA, Visser O, et al (2013). Lower mortality from nasopharyngeal cancer in The Netherlands since 1970 with differential incidence trends in histopathology. Oral Oncol, 49, 237-43. https://doi.org/10.1016/j.oraloncology.2012.09.016
  2. Bei JX, Li Y, Jia WH, et al (2010). A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Nat Genet, 42, 599-603. https://doi.org/10.1038/ng.601
  3. Cabrera C, Artacho R, Gimenez R (2006). Beneficial effects of green tea--a review. J Am Coll Nutr, 25, 79-99. https://doi.org/10.1080/07315724.2006.10719518
  4. Chang ET, Adami HO (2006). The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev, 15, 1765-77. https://doi.org/10.1158/1055-9965.EPI-06-0353
  5. Chen JY, Liu MY, Chen CJ, et al (1985). Antibody to epstein-barr virus-specific DNase as a marker for the early detection of nasopharyngeal carcinoma. J Med Virol, 17, 47-9. https://doi.org/10.1002/jmv.1890170107
  6. Deng W, Long L, Li JL, et al (2014). Mortality of major cancers in Guangxi, China: sex, age and geographical differences from 1971 and 2005. Asian Pac J Cancer Prev, 15, 1567-74. https://doi.org/10.7314/APJCP.2014.15.4.1567
  7. Ekburanawat W, Ekpanyaskul C, Brennan P, et al (2010). Evaluation of non-viral risk factors for nasopharyngeal carcinoma in Thailand: results from a case-control study. Asian Pac J Cancer Prev, 11, 929-32.
  8. Han BL, Xu XY, Zhang CZ, et al (2012). Systematic review on Epstein-Barr virus (EBV) DNA in diagnosis of nasopharyngeal carcinoma in Asian populations. Asian Pac J Cancer Prev, 13, 2577-81. https://doi.org/10.7314/APJCP.2012.13.6.2577
  9. Hildesheim A, Chen CJ, Caporaso NE, et al (1995). Cytochrome P4502E1 genetic polymorphisms and risk of nasopharyngeal carcinoma: results from a case-control study conducted in Taiwan. Cancer Epidemiol Biomarkers Prev, 4, 607-10.
  10. Hsu C, Shen YC, Cheng CC, et al (2006). Difference in the incidence trend of nasopharyngeal and oropharyngeal carcinomas in Taiwan: implication from age-period-cohort analysis. Cancer Epidemiol Biomarkers Prev, 15, 856-61. https://doi.org/10.1158/1055-9965.EPI-05-0821
  11. Huang TR, Zhang SW, Chen WQ, et al (2012). Trends in nasopharyngeal carcinoma mortality in China, 1973-2005. Asian Pac J Cancer Prev, 13, 2495-502. https://doi.org/10.7314/APJCP.2012.13.6.2495
  12. Jia WH, Huang QH, Liao J, et al (2006). Trends in incidence and mortality of nasopharyngeal carcinoma over a 20-25 year period (1978/1983-2002) in Sihui and Cangwu counties in southern China. BMC Cancer, 6, 178. https://doi.org/10.1186/1471-2407-6-178
  13. Jia WH, Pan QH, Qin HD, et al (2009). A case-control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk in Cantonese. Carcinogenesis, 30, 2031-6. https://doi.org/10.1093/carcin/bgp239
  14. Kim HJ, Fay MP, Feuer EJ, et al (2000). Permutation tests for joinpoint regression with applications to cancer rates. Stat Med, 19, 335-51. https://doi.org/10.1002/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z
  15. Lau HY, Leung CM, Chan YH, et al (2013). Secular trends of salted fish consumption and nasopharyngeal carcinoma: a multi-jurisdiction ecological study in 8 regions from 3 continents. BMC Cancer, 13, 298. https://doi.org/10.1186/1471-2407-13-298
  16. Lee AW, Foo W, Mang O, et al (2003). Changing epidemiology of nasopharyngeal carcinoma in Hong Kong over a 20- year period (1980-99): an encouraging reduction in both incidence and mortality. Int J Cancer, 103, 680-5. https://doi.org/10.1002/ijc.10894
  17. Luo J, Chia KS, Chia SE, et al (2007). Secular trends of nasopharyngeal carcinoma incidence in Singapore, Hong Kong and Los Angeles Chinese populations, 1973-1997. Eur J Epidemiol, 22, 513-21. https://doi.org/10.1007/s10654-007-9148-8
  18. M. P. Curado BEHR 2007. Cancer Incidence in Five Continents Volume IX, Lyon, France, IARC Scientific Publications No. 160.
  19. Parkin DM, Bray F (2009). Evaluation of data quality in the cancer registry: principles and methods Part II. Completeness. Eur J Cancer, 45, 756-64. https://doi.org/10.1016/j.ejca.2008.11.033
  20. Polesel J, Serraino D, Negri E, et al (2013). Consumption of fruit, vegetables, and other food groups and the risk of nasopharyngeal carcinoma. Cancer Causes Control, 24, 1157-65. https://doi.org/10.1007/s10552-013-0195-z
  21. Sun LM, Epplein M, Li CI, et al (2005). Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002. Am J Epidemiol, 162, 1174-8. https://doi.org/10.1093/aje/kwi345
  22. Tsao SW, Yip YL, Tsang CM, et al (2014). Etiological factors of nasopharyngeal carcinoma. Oral Oncol, 50, 330-8. https://doi.org/10.1016/j.oraloncology.2014.02.006
  23. Tse KP, Su WH, Chang KP, et al (2009). Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3. Am J Hum Genet, 85, 194-203. https://doi.org/10.1016/j.ajhg.2009.07.007
  24. Wei K, Xu Y, Liu J, et al (2010). No incidence trends and no change in pathological proportions of nasopharyngeal carcinoma in Zhongshan in 1970-2007. Asian Pac J Cancer Prev, 11, 1595-9.
  25. Wei WI, Sham JS (2005). Nasopharyngeal carcinoma. Lancet, 365, 2041-54. https://doi.org/10.1016/S0140-6736(05)66698-6
  26. Xie SH, Gong J, Yang NN, et al (2012a). Time trends and ageperiod- cohort analyses on incidence rates of nasopharyngeal carcinoma during 1993-2007 in Wuhan, China. Cancer Epidemiol, 36, 8-10. https://doi.org/10.1016/j.canep.2011.07.002
  27. Xie SH, Yu IT, Tse LA, et al (2013). Sex difference in the incidence of nasopharyngeal carcinoma in Hong Kong 1983- 2008: suggestion of a potential protective role of oestrogen. Eur J Cancer, 49, 150-5. https://doi.org/10.1016/j.ejca.2012.07.004
  28. Xie WC, Chan MH, Mak KC, et al (2012b). Trends in the incidence of 15 common cancers in Hong Kong, 1983-2008. Asian Pac J Cancer Prev, 13, 3911-6. https://doi.org/10.7314/APJCP.2012.13.8.3911
  29. Yang WS, Yang C, Zheng JW, et al (2009). Time trend analysis of incidence rate for nasopharyngeal carcinoma in urban Shanghai. Zhonghua Liu Xing Bing Xue Za Zhi, 30, 1171-4 (in Chinese).
  30. Yu MC, Mo CC, Chong WX, et al (1988). Preserved foods and nasopharyngeal carcinoma: a case-control study in Guangxi, China. Cancer Res, 48, 1954-9.

Cited by

  1. Analysis on Clinical Characteristics and Influencing Factors of Patients with Locoregionally Advanced Nasopharyngeal Carcinoma vol.16, pp.10, 2015, https://doi.org/10.7314/APJCP.2015.16.10.4393
  2. Epidemiology of Nasopharyngeal Cancers in Iran: A 6-year Report vol.16, pp.10, 2015, https://doi.org/10.7314/APJCP.2015.16.10.4447
  3. Declining Incidence of Nasopharyngeal Carcinoma in Brunei Darussalam: a Three Decade Study (1986-2014) vol.16, pp.16, 2015, https://doi.org/10.7314/APJCP.2015.16.16.7097
  4. Nasopharyngeal Carcinoma Incidence in North Tunisia: Negative Trends in Adults but not Adolescents, 1994-2006 vol.16, pp.7, 2015, https://doi.org/10.7314/APJCP.2015.16.7.2653
  5. Active and Passive Smoking and Risk of Nasopharyngeal Carcinoma: A Population-Based Case-Control Study in Southern China vol.185, pp.12, 2017, https://doi.org/10.1093/aje/kwx018
  6. Nasopharyngeal carcinoma incidence and mortality in China, 2013 vol.36, pp.1, 2017, https://doi.org/10.1186/s40880-017-0257-9
  7. Ophthalmic involvement in nasopharyngeal carcinoma vol.36, pp.2, 2017, https://doi.org/10.1080/01676830.2017.1279658
  8. Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer vol.377, pp.6, 2017, https://doi.org/10.1056/NEJMoa1701717
  9. Diet Quality Scores and Risk of Nasopharyngeal Carcinoma in Chinese Adults: A Case-Control Study vol.8, pp.3, 2016, https://doi.org/10.3390/nu8030112
  10. Tolfenamic Acid Inhibits the Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma: Involvement of p38-Mediated Down-Regulation of Slug vol.57, pp.3, 2016, https://doi.org/10.3349/ymj.2016.57.3.588
  11. Global trends in nasopharyngeal cancer mortality since 1970 and predictions for 2020: Focus on low-risk areas vol.140, pp.10, 2017, https://doi.org/10.1002/ijc.30660
  12. PTPN12 Affects Nasopharyngeal Carcinoma Cell Proliferation and Migration Through Regulating EGFR vol.33, pp.2, 2018, https://doi.org/10.1089/cbr.2017.2254