• Journal of the Korea Institute of Building Construction
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• v.19 no.2
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• pp.185-192
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• 2019

Construction has been well known as the industry in which accidents occur more often than other industries. The efforts to eliminate the accidents at construction sites need to be continuously conducted because they tend to cause the social problems such as massive loss of life and property. According to the Korea Occupational Safety and Health Agency (KOSHA), 26,570 (29.3 percent) out of 90,656 workers in total industrial accidents have been occurred in the construction industry in 2016. Particularly, the falling victims are the largest number, which is about 8,699. This number is increasing due to the increase of the large scale, high-rise, and complex construction structures and the various construction methods. In reality, there is a lack of analysis on the risk factors of safety accidents and preventive measures. Therefore, in this study, we have selected risk factors by analyzing the accident cases at construction sites. Based on the results, we conducted a safety practitioner-focused survey and had an interview with safety managers. In analyzing the cases, we have categorized them into three groups such as upper, middle, and lower and compared their statistical results. This study are expected to provide safety management guidelines with workers and safety managers to prevent previously fall accidents at construction site.

• Journal of the Korea Convergence Society
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• v.12 no.3
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• pp.389-399
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• 2021

This study is the quasi-experimental research of nonequivalent groups and is designed to investigate the effects of an aquatic exercise program with diabetes self management education on the self care efficacy, self care behaviors in diabetic patients in community. The subjects of this study were 26 patients in the experimental group who participated in the aquatic exercise program and 25 patients in the control group who did not paricipated in. And they were registered at the W Health Clinic in D city. The aquatic exercise program was conducted twice a week for 80 minutes, and consisted of a 30 minutes diabetes self management education and a 50 minutes aquatic exercise. After this program, there were significant differences in FBS(p=.047), HbA1c(p<.001), diabetes self efficacy(p<.001), and self care behaviors(p<.001). In order to reduce the prevalence of diabetes and prevent complications in the community, it is believed that the constant operation of aquatic exercise programs including self management education is necessary.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.413-419
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• 2021

The purpose of this study was to investigate the ability to treat and prevent infection by multiple Gram-negative bacterial pathogens as a last choice option in the treatment of serious infections in clinical settings. The global spread of extended-spectrum 𝛽-lactamases (ESBLs) and/or carbapenemases in microorganisms are of enormous concern to health services because they are often associated with multi-drug resistance which significantly restricts the antibiotic treatment options. In this study, the antimicrobial resistance profiles of bacteria isolated from South Korean market-derived meat samples were determined by the disc diffusion method. PCR was used to detect the presence of antibiotic resistance genes and ESBL producing genes. In total, we tested 181 isolated colonies from 36 market-derived meat samples. Single PCR and DNA sequencing results revealed that genes blaVIM, blaBIC, blaKPC, and blaSIM were present in the bacteria isolated from retail meat. The bacteria in the meat were separately sequenced and based on alignment, four different bacteria were identified. These findings suggest that bacteria found in retail meats are a reservoir for the spreading of ESBL blaVIM, blaBIC, blaKPC, and blaSIM resistance genes and bacteria strains.

• Natural Product Sciences
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• v.27 no.2
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• pp.86-98
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• 2021

This study was designed to characterize the effect of ginsenoside-Rg2 (Rg2), one of panaxatriol saponins isolated from Korean ginseng root, on the release of catecholamines (CA) in the perfused model of the rat adrenal medulla, and also to establish its mechanism of action. Rg2 (3~30 µM), administered into an adrenal vein for 90 min, depressed acetylcholine (ACh)-induced CA secretion in a dose- and time-dependent manner. Rg2 also time-dependently inhibited the CA secretion induced by 3-(m-chloro-phenyl-carbamoyl-oxy)-2-butynyltrimethyl ammonium chloride (McN-A-343), 1.1-dimethyl-4-phenyl piperazinium iodide (DMPP), and angiotensin II (Ang II). Also, during perfusion of Rg2, the CA secretion induced by high K⁺, veratridine, cyclopiazonic acid, methyl-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoro-methyl-phenyl)-pyridine-5-carboxylate (Bay-K-8644) depressed, respectively. In the simultaneous presence of Rg2 and N^ω-nitro-L-arginine methyl ester hydrochloride ʟ-NAME), the CA secretion induced by ACh, Ang II, Bay-K-8644 and veratridine was restored nearly to the extent of their corresponding control level, respectively, compared to those of inhibitory effects of Rg2-treatment alone. Virtually, NO release in adrenal medulla following perfusion of Rg2 was significantly enhanced in comparison to the corresponding spontaneous release. Also, in the coexistence of Rg2 and fimasartan, ACh-induced CA secretion was markedly diminished compared to the inhibitory effect of fimasartan-treated alone. Collectively, these results demonstrated that Rg2 suppressed the CA secretion induced by activation of cholinergic as well as angiotensinergic receptors from the perfused model of the rat adrenal gland. This Rg2-induced inhibitory effect seems to be exerted by reducing both influx of Na⁺ and Ca²⁺ through their ionic channels into the adrenomedullary cells as well as by suppressing Ca²⁺ release from the cytoplasmic calcium store, at least through the elevated NO release by activation of NO synthase, which is associated to the blockade of neuronal cholinergic and AT₁-receptors. Based on these results, the ingestion of Rg2 may be helpful to alleviate or prevent the cardiovascular diseases, via reduction of CA release in adrenal medulla and consequent decreased CA level in circulation.

• Journal of the Korean Applied Science and Technology
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• v.38 no.1
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• pp.241-262
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• 2021

This paper reviewed the necessity of a information and communication technology (ICT)-based smart livestock system as a development strategy for the animal life industry in the future. It also predicted the trends of livestock and animal food until 2050, 30 years later. Worldwide, livestock raising and consumption of animal food are rapidly changing in response to population growth, aging, reduction of agriculture population, urbanization, and income growth. Climate change can change the environment and livestock's productivity and reproductive efficiencies. Livestock production can lead to increased greenhouse gas emissions, land degradation, water pollution, animal welfare, and human health problems. To solve these issues, there is a need for a preemptive future response strategy to respond to climate change, improve productivity, animal welfare, and nutritional quality of animal foods, and prevent animal diseases using ICT-based smart livestock system fused with the 4th industrial revolution in various aspects of the animal life industry. The animal life industry of the future needs to integrate automation to improve sustainability and production efficiency. In the digital age, intelligent precision animal feeding with IoT (internet of things) and big data, ICT-based smart livestock system can collect, process, and analyze data from various sources in the animal life industry. It is composed of a digital system that can precisely remote control environmental parameters inside and outside the animal husbandry. The ICT-based smart livestock system can also be used for monitoring animal behavior and welfare, and feeding management of livestock using sensing technology for remote control through the Internet and mobile phones. It can be helpful in the collection, storage, retrieval, and dissemination of a wide range of information that farmers need. It can provide new information services to farmers.

• Journal of Food Hygiene and Safety
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• v.35 no.6
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• pp.587-601
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• 2020

Exposure to hazardous substances occurs through multiple pathways. Aggregated risk assessment, which includes all potential exposure pathways to a single toxicant, is necessary to prevent exposure to harmful substances. We aimed to estimate cadmium and lead exposure through various media, such as food, water, air, smoking, cosmetics, and female hygiene products. This study covered 10,733 subjects from the Seventh Korea National Health and Nutrition Examination Survey(2016, 2017). Dietary exposure was estimated using 24-hour recall data. For water and inhalational exposure, regional variations were considered. Water was classified as tap, bottled, and public water. Inhalational exposure was estimated using the '2014 Time Use Survey' based on daily lifestyle and social status. The frequency and volume of cosmetic usage were randomly approximated by sex and age. Post-menarcheal and premenopausal women were assumed to use feminine hygiene products. Non-carcinogenic aggregated risks were estimated using the Aggregate Risk Index from EPAs and the Total Exposure Hazard Index from Korean government guidelines. For carcinogenic risk assessment, excessive cancer risk was estimated. Ingestion, especially food, was the major route for both cadmium and lead exposure. Smoking was also associated with high cadmium exposure. Exposure to lead from cosmetics was remarkable but not critical. In aggregate risk assessments, median cadmium and lead exposure did not exceed the reference value. Sex, age, smoking status, and income affected exposure levels, unlike to regional variations.

• The Journal of the Korea Contents Association
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• v.21 no.5
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• pp.627-637
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• 2021

Many efforts have been made to prevent alcohol related harms such as health problems and socio-economic problems. Among them, the method of improving drinking behavior at the individual level is the most direct intervention. The effectiveness of the use of protective behavior strategies(PBS) has been widely known in Western countries. The purpose of this study is to empirically verify whether the use of PBS affects alcohol related harms in Korean adults. The survey has been conducted on 2,000 adult men and women. As a result, it is found that the use of PBS reduced alcohol related harms in adults. Among the PBS, the biggest impact on alcohol related harms is the area related serious harm reduction strategy, followed by restrictions on 'manner of drinking'. The effects of 'limiting/ stopping of drinking' is not significant. In addition, drinking frequency, binge drinking, and drinking motivations have significant positive effects on alcohol-related harms, and only social motivation has a negative effect. In this work, we propose follow-up studies on identifying relationships between protective behaviors and alcohol related factors through longitudinal studies and strengthening the use of protective behavior strategies that applied to the refined target populations.

• Journal of radiological science and technology
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• v.44 no.6
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• pp.671-677
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• 2021

Interest in the everyday hazards of radon has recently increased as such, this study attempted to examine the dangers of radon in spilled groundwater by comparing the radon concentrations of the drained groundwater and tap water used in recirculating systems in Incheon Subway restrooms. At five stations of Incheon Subway Line 1 and three stations of Line 2, drained groundwater is recirculated and used in restrooms for toilet flushing. Stations restroom tap water for hand washing that used as a control and the measured values of each were compared. With the cooperation of Incheon Transportation Corporation, samples of spilled groundwater and tap water were collected sealed to prevent contact with the air, and a DURRIDGE RAD7 was used as the experimental equipment. The collected samples were subjected to radial equilibration for approximately 3.5 h, at which the radon concentration reached its maximum, and then calculated as 10 measurements using the RAD7 underwater radon measurement mode. In all eight stations, the radon concentration in tap water was lower than the recommended amount. However, in an average of 7 out of the eight stations, the radon concentration in the effluent groundwater was 100 times higher than that in tap water. Since high radon concentrations in groundwater runoff can be harmful to humans, and there is no accurate standard for radon concentrations in domestic water, it is necessary to continuously monitor radon in water and prepare a guidance of recommended values.

• Journal of Nutrition and Health
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• v.54 no.6
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• pp.603-617
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• 2021

Purpose: This study was carried out to investigate the effect of amaranth seed extracts on glycemic regulation in HepG2 cells. The 80% ethanol extracts of amaranth seeds were used to evaluate α-amylase and α-glucosidase activities, cell viability, glucose uptake and messenger RNA (mRNA) expression levels of acetyl-CoA carboxylase (ACC), glucose transporter (GLUT)-2, GLUT-4, insulin receptor substrate (IRS)-1 and IRS-2. Methods: The samples were prepared and divided into 4 groups, including germinated black amaranth (GBA), black amaranth (BA), germinated yellow amaranth (GYA) and yellow amaranth (YA). Glucose hydrolytic enzyme, α-amylase and α-glucosidase activities were examined using a proper protocol. In addition, cell viability was measured by MTT assay. Glucose uptake in cells was measured using an assay kit. The mRNA expression levels of ACC, GLUT-2, GLUT-4, IRS-1 and IRS-2 were measured by reverse transcription polymerase chain reaction. Results: The inhibitory activities of α-amylase and α-glucosidase were highly observed in GBA, followed by BA, GYA and YA. Similar results were observed for glucose. The GBA effect was similar compared to the positive control group. The mRNA expression levels of ACC, GLUT-2, GLUT-4, IRS-1, and IRS-2 were significantly increased. The potential hypoglycemic effects of amaranth seed extracts were observed due to the increase in glucose metabolic enzyme activity, and glucose uptake was mediated through the upregulation of ACC, GLUT-2, GLUT-4, IRS-1, and IRS-2 expression levels. Conclusion: Our findings suggest that the amaranth seed is a potential candidate to prevent a diabetes. The present study demonstrated the possibility of using amaranth seeds, especially GBA and BA for glycemic control.

• Journal of Preventive Medicine and Public Health
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• v.54 no.6
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• pp.412-421
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• 2021

Objectives: Non-alcoholic fatty liver disease (NAFLD) is an increasingly prevalent metabolic disease. Muscle is known to influence NAFLD development. Therefore, this study aimed to determine the relationships among low muscle mass, NAFLD, and hepatic fibrosis using various definitions of low muscle mass and NAFLD diagnostic methods, including magnetic resonance imaging-based proton density fat fraction (MRI-PDFF). Methods: This cross-sectional study included 320 participants (107 males, 213 females) from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population cohort. Muscle mass was assessed using whole-body dual-energy X-ray absorptiometry and adjusted for the height squared, body weight, and body mass index (BMI). NAFLD was diagnosed using ultrasonography (US), MRI-PDFF, and the comprehensive NAFLD score (CNS). Hepatic fibrosis was assessed using magnetic resonance elastography. Multivariable logistic and linear regression analyses were performed to determine the aforementioned associations. Results: According to US, 183 participants (57.2%) had NAFLD. Muscle mass adjusted for body weight was associated with NAFLD diagnosed using US (odds ratio [OR], 3.00; 95% confidence interval [CI], 1.70 to 5.31), MRI-PDFF (OR, 2.00; 95% CI, 1.13 to 3.53), and CNS (OR, 3.39; 95% CI, 1.73 to 6.65) and hepatic fibrosis (males: β=-0.070, p<0.01; females: β=-0.037, p<0.04). Muscle mass adjusted for BMI was associated with NAFLD diagnosed by US (OR, 1.71; 95% CI, 1.02 to 2.86) and CNS (OR, 1.95; 95% CI, 1.04 to 3.65), whereas muscle mass adjusted for height was not associated with NAFLD. Conclusions: Low muscle mass was associated with NAFLD and liver fibrosis; therefore, maintaining sufficient muscle mass is important to prevent NAFLD. A prospective study and additional consideration of muscle quality are needed to strengthen the findings regarding this association.