• Journal of Preventive Medicine and Public Health
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• 제27권4호
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• pp.763-776
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• 1994

Recent studies reveal that grip forces during the hand-arm vibration are most significant for the genesis of vibration-induced white linger syndrome. Therefore, exerted grip forces and skin temperatures of fingers were regarded as dependent variables in experiments and the effects of grip temperature, noise, pushing force, vibration and the combined effect of vibration and pushing force were studied. The objectives of the present study were, first, to varify and compare the changes of grip force affected by grip temperature, noise, pushing force, vibration and the combined effect of vibration and pushing force and, second, to observe the reaction of finger skin temperature affected by above factors. Forty-six healthy male students ($25.07{\pm}2.85$) participated in five systematically permuted trials, which endured 4 minutes each other. Experiments were executed in a special chamber with an air temperature of 21C. In each experiments, the subjects were exposed to five experiment types: (1) grip force of 25N only, (2) pushing force of 50N, (3) acceleration of vibration $7.1m/sec^2(z-direction)$, (4) pink noise of 95 dB (A) and (5) combination of pushing force 50N and acceleration of vibration $7.1m/sec^2$. A repeated-measures analysis of variance (ANOVA) was performed on the grip force to test whether it was affected by noise, pushing force, vibration and pushing force. The present results show that vibration was significantly related to the increase of grip force, but the other factors, such as pushing force, noise and grip temperature had no signigicant influence on the increase of grip force, and that the reaction of finger skin temperature were significantly affected by the skin temperature at start of experiment and grip temperature, not grip force and other experimental conditions. Therefore, we suggest that the management for decreasing the grip force is meaningful to prevent the occurrence of Hand-arm vibration syndrome (HAVS).

• 응용통계연구
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• 제31권1호
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• pp.77-96
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• 2018

주택연금은 계약기간이 확정되어 있지 않기 때문에 계약 종료 시점에 대한 확률분포 예측이 장수리스크 관리를 위하여 중요하다. 따라서 고령화의 주요인인 기대수명의 연장은 연금 재정건전성에 심각한 영향을 끼칠 수 있기 때문에 사망률의 개선 추세가 적절히 반영된 사망률 예측 연구가 선행될 필요가 있다. 본 연구에서는 Lee-Carter (LC) 모형과 연생모형을 이용하여 주택연금 계리모형에 사망률 개선 효과를 반영하였다. 전통적 LC 모형을 통한 사망률 예측 방식은 미래 사망률이 지나치게 개선되는 현상을 보이고 있기 때문에 사망률 개선효과를 조금 더 적절한 수준으로 보정하고자 본 연구에서는 사망확률 분포의 편중을 나타내는 왜도를 활용한 LC 모형을 적용하였다. 왜도 예측 방식을 LC 모형에 적용한 방법론을 사용하여 주택연금 월 지급금을 산출해본 결과 전통적 LC 모형의 사망률 예측보다 사망률 개선효과를 더 적게 반영하여 더 큰 월 지급금이 산출되었고, 왜도 활용 LC 모형에 의한 이러한 결과는 장수 리스크를 덜 왜곡한다는 데 의의가 있다고 볼 수 있다. 본 연구 결과는 사망률 감소 추세를 적절하게 반영한 위험률을 계산하여 주택연금의 발행기관 및 보증기관의 적정한 월 지급금 지급과 차후 월 지급금의 과대지급으로 인한 지급불능을 방지할 수 있는 리스크 관리 방법으로 이용될 수도 있다.

• Journal of Nutrition and Health
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• 제10권2호
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• pp.18-26
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• 1977

Among animals, the rabbit is known to be affected most sensitively by dietary changes and to be most susceptible to atherosclerosis. The exact reason is still unknown as to whether the primary cause is intrinsic (tissue itself) or extrinsic such as a blood factor which could be influenced by various dietary means. It is of utmost importance to check the nutritional quality of rabbit meat before it is accepted and adapted as a daily food item. To evaluate nutritional quality of rabbit meat, studies on various aspects of lipid components were carried out in comparison with other animal meats such as beef, pork and chicken also included in the study was the question whether the cooking and storage conditions influence the composition of fatty acids and cholesterol level. Some results and findings are listed below: 1. The content of linoleic acid (18 : 2), one of the essential fatty acids, was much higher in rabbit meat compared to the other meats. The Percentages of this Polyunsaturated fatty acids, was much higher in rabbit meat compared to the other meats. The percentages of this polyunsaturated fatty acid in terms of total fatty acids were $37.3{\pm}3.7$, 5.9, 14.5, and 21.9% for rabbit, beef, pork, and chicken respectively. The degree of unsaturation was high not only in meat but also in liver and adipose tissue of rabbit. The values of iodine number, the indication of degree of unsaturation, were known to be $102{\sim}107$, $32{\sim}47$, $46{\sim}67$, and $55{\sim}77$ for rabbit, beef, pork, and chicken respectively. Such a high proportion of this polyunsaturated fatty acid contained in rabbit meat could be harmful due to their Peroxidation effect. 2. A small amount of lower (short chain) fatty acids was isolated from rabbit tussues, which were not observed in other animal's tissues. The significance of this small amount of short chain fatty acids contained in rabbit meat remained an open question. 3. The concentration of total cholesterol in rabbit meat was similar to that of otherr but the content of esterified cholesterol was higher in rabbit meat. This was probably due to the perference of cholesterol to esterify with unsaturated fatty acids. By roasting the percentage of Polyunsaturated fatty acids was decreased while saturated palmitic acid was proportionally increased. 4 The composition of fatty acids were affected more by dry heat than moist heat. More research should be pursued to improve methods of preservation and storage to prevent possible peroxidation and rancidity problems of rabbit meat. In the meantime, the public should be informed to eat fresh rabbit meat and not to store it for a long period of time. This study was supported by the Ministry of Science and Technology in Korea.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1247-1247
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• 2001

Constituents of animal biofluids such as milk, blood and urine contain information specifically related to metabolic and health status of the ruminant animals. Some changes in composition of biofluids can be attributed to disease response of the animals. Mastitis is a major problem for the global dairy industry and causes substantial economic losses from decreasing milk production and reducing milk quality. The purpose of this study was to investigate potential of NIRS combined with multivariate analysis for cow's mastitis diagnosis based on NIR spectra of milk, blood and urine. A total of 112 bulk milk, urine and blood samples from 4 Holstein cows were analyzed. The milk samples were collected from morning milking. The urine samples were collected before morning milking and stored at -35$^{\circ}C$ until spectral analysis. The blood samples were collected before morning milking using a catheter inserted into the carotid vein. Heparin was added to blood samples to prevent coagulation. All milk samples were analyzed for somatic cell count (SCC). The SCC content in milk was used as indicator of mastitis and as quantitative parameter for respective urine and blood samples collected at same time. NIR spectra of blood and milk samples were obtained by InfraAlyzer 500 spectrophotometer, using a transflectance mode. NIR spectra of urine samples were obtained by NIR System 6500 spectrophotometer, using 1 mm sample thickness. All samples were divided into calibration set and test set. Class variable was assigned for each sample as follow: healthy (class 1) and mastitic (class 2), based on milk SCC content. SIMCA was implemented to create models of the respective classes based on NIR spectra of milk, blood or urine. For the calibration set of samples, SIMCA models (model for samples from healthy cows and model for samples from mastitic cows), correctly classified from 97.33 to 98.67% of milk samples, from 97.33 to 98.61% of urine samples and from 96.00 to 94.67% of blood samples. From samples in the test set, the percent of correctly classified samples varied from 70.27 to 89.19, depending mainly on spectral data pretreatment. The best results for all data sets were obtained when first derivative spectral data pretreatment was used. The incorrect classified samples were 5 from milk samples,5 and 4 from urine and blood samples, respectively. The analysis of changes in the loading of first PC factor for group of samples from healthy cows and group of samples from mastitic cows showed, that separation between classes was indirect and based on influence of mastitis on the milk, blood and urine components. Results from the present investigation showed that the changes that occur when a cow gets mastitis influence her milk, urine and blood spectra in a specific way. SIMCA allowed extraction of available spectral information from the milk, urine and blood spectra connected with mastitis. The obtained results could be used for development of a new method for mastitis detection.

• 한국식품영양학회지
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• 제23권4호
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• pp.607-614
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• 2010

The aim of this study was to investigate the quality characteristics of sponge cakes with added rice flour produced by a modified genoise method to prevent volume reduction. A control group and experimental group I were prepared by the genoise method and experimental groups II, III, and IV were produced by a modified genoise method in which they were mixed with wheat flour and water to a make paste to form gluten for 3, 6, and 9 minutes, respectively. One third of the wheat flour in all experimental groups was replaced by rice flour. The control and experimental groups were compared in terms of quality characteristics, including batter specific gravity, volume, color, textural characteristics, and sensory qualities, to determine the optimal pasting time for wheat flour in the formulation. The specific gravity of the experimental groups was higher than that of the control and decreased with increasing wheat flour pasting time. The volume of experimental group I was lower than that of the control group, and the volume values of experimental groups III and IV, made by the modified genoise method, were higher than that of the control group. $dL^*$ and $db^*$values for the crust and inside of the cake were lower in the experimental groups than in the control. The $dL^*$ value, indicating brightness, increased as pasting time increased. The hardness values of experimental groups I and IV were higher than that of the control whereas experimental groups II and III had lower hardness values. Chewiness was higher in the control group, as well as experimental groups I and IV than in the experimental groups II and III. The gumminess of experimental group IV was highest. Cohesiveness decreased by adding rice flour to the sponge cake. Sensory attributes of cell uniformity, tenderness, moistness, taste, and overall acceptability had the highest scores in experimental group III. Based on these results, we conclude that the quality of sponge cake containing one third of the wheat flour replaced by rice flour is best with 6 minutes pasting of the wheat flour to form gluten.

• Childhood Kidney Diseases
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• 제13권1호
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• pp.75-83
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• 2009

목 적 : 비만은 이제 전 세계적인 보건 문제 중의 하나로서 고혈압과 당뇨를 통해 만성 신장 질환 그리고 말기 신부전을 매개한다는 것은 이미 잘 알려진 사실이다. 본 연구에서는 현미경적 혈뇨 또는 단백뇨를 보여 본원에 내원하여 신생검을 시행한 초기 만성신질환 환아 중 체질량 지수 25 이상 되는 과체중군에서 신장 질환의 위험도를 증가시키고 신기능 악화인자로 작용할 수 있는 임상인자들에 대해 정상 체중군의 신질환 환아들과 비교 분석하였다. 방 법 : 2003년 1월부터 2007년 12월까지 지난 5년간 경희대학교 소아청소년과에 지속적인 혈뇨 또는 단백뇨 동반을 주소로 신생검을 시행한 4-18세의 소아 및 청소년 가운데 체질량 지수가 25 이상인 과체중군 26명(남:여=19:7)과 정상 체중의 대조군 49명(남:여=35:14), 총 75명(남:여=54:21)을 대상으로 신체 계측하고, 24시간 요 검사 및 일반 혈액학, 생화학 검사를 측정하였다. 결 론 : 본 연구에서 신질환의 진행과 악화, 심혈관계 합병증, 지방간의 진행과 관계있는 인자들이 과체중군의 환아들에게서 만성 신질환 초기에도 유의있게 높은 수치를 보여주었다. 따라서 과체중을 동반한 만성 신질환 환아들의 경우 비만에 대한 주의 깊은 관찰과 신질환의 악화를 막기 위한 조기 진단과 치료 및 예방에 힘쓰는 것이 필요할 것으로 사료된다.

• Journal of Nutrition and Health
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• 제37권7호
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• pp.540-549
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• 2004

Infants and children with food related Atopic Dermatitis (AD) need extra dietary efforts to maintain optimal nutrition due to food restriction to prevent allergy reactions. However, nutrition ignorance and food faddism make patients even more confused and practice desirable diet more difficult. The objective of this study was to report the AD patients' malnutrition cases in Korea. We report on 2 cases of severe nutritional deficiency caused by consuming macrobiotic diets which avoid processed foods and most animal foods, i.e. one of vegetarian diet. Case 1, a 12-month-old male child, was admitted with severe marasmus. Because of a history of AD, he was started on mixed grain porridge at 3 months without any breast milk or formula feeding. His caloric intake was 66% and protein intake was 69% of the recommended dietary allowance. Patient's height and weight was under 3th percentile. On admission the patient was unable to crawl or roll over. Case 2, a 9-month-old AD female patient, was diagnosed with kwashiorkor and rickets. She was also started on mixed grain porridge at 100 days due to AD. Her caloric intake has been satisfied recommended dietary allowance until 7 months, however, she conducted sauna bath therapy and reduced both energy and protein intake at 8 months. The amount of protein intake for case 2 was higher than recommended dietary allowance, but, sauna therapy and severe AD with intakes of low guality protein may increase patient's protein requirement resulting in kwashiorkor. Case 2 patient's height and weight was on 3th percentile. Both cases showed low intake of calcium, iron, zinc, vitamin A, vitamin E and especially very low intake of vitamin B$_{12}$ and vitamin D. Allergy tests for certain foods had not done prior to admission for both cases. They followed the dietary advise operated by macrobiotic diet internet site. In conclusion, AD infants' parents and caregivers should contact a pediatrician trained as a specialist in allergy for accurate diagnosis. For infant patients, breast or formula feeding including hypoallergenic formula should be continued until their one year of age. When certain foods need to be restricted or to follow special diets such as vegetarian diet, consultation with pediatrician and dietitian is needed.d.

• Journal of Nutrition and Health
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• 제9권4호
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• pp.19-27
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• 1976

Perilla (frutescens) seed oil, which is widely used as a source of vegetable oil in Korea, contains a strikingly large amount (58.4% of total fatty acids) of polyunsaturated linolenic acid (18 : 3) which is one of the essential fatty acids. Our hypothesis was that vitamin E contained in this oil would not be enough to prevent peroxidation of this polyunsaturated oil. A comparative study was carried out using rats and chicks devided into seven groups with various diet combinations emphasizing fat sources for the period of four weeks. The level of fat in each diet was 15% and animals were fed ad libitum. Various diet combinations were as follows; perilla seed oil and sesame seed oil with and without vitamin E supplementation, tallow as a saturated fat source and perilla seed hull group (10% at the expense of carbohydrate). The fat constituents of control group were consisted of 50% vegetable oil and 50% animal fat. A few important findings are as follows: 1. Rats fed perilla seed oil lost their hair focally around the neck and suffered from a bad skin lesion at the same place. In chicks, yellow pigmentation both of feather and of skin was clearly observed only in groups fed perilla seed oil with or without vitamin E supplementation. The basis of biochemical mechanisms of this phenomena remains as an important research interest. 2. The mean value for hematocrit was significantly lower for the chicks fed perilla seed oil than for those fed control diet. This result seems to be attributable to the effect on the red cell membrane known as peroxidation-hemolysis of vitamin E deficiency. 3. The serum cholesterol level was higher for the rats fed perilla seed oil than for those fed control diet, whereas in chicks the group fed perilla seed oil showed lower value than the control group indicating that different animal species could vary in their responses to the same diet. 4. In pathological examinations, the sign of hepatic fibrosis was seen in the perilla seed hull group and it was noticeable that the level of hepatic RNA was significantly increased in the rat recovering from vitamin E deficiency. It is hoped that more detailed studies on perilla seed oil and hulls will soon be carried out in many aspects especially i) at various levels of fat in the diet, ii) in relation to dietary selenium level and iii) to find an optimum level of dietary essential fatty acids in terms of P/S ratio using various animal species. In the mean time, the public should be informed to preserve this particular oil with care to minimize fatty acid oxidation and should be discouraged from overconsuming this oil. This study was supported by UB (United Board) Research Grant (Graduate School, Yonsei University, Seoul, Korea)

• 한국산학기술학회논문지
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• 제21권11호
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• pp.851-860
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• 2020

인구 고령화와 건강 복지에 대한 사회적 관심이 높아지면서 재활복지기를 포함한 실버 및 헬스케어 산업과 관련한 연구들이 활발하게 진행되고 있다. 본 연구에서는 기존에 1차적으로 설계·제작되었던 이·승강 전동휠체어를 사용자 측면에서 보다 더 안전성과 편의성을 갖도록 개선하고자 하였다. 사용자 체형을 고려한 헤드레스트 높이조절 기능의 시트 디자인, 사용성 증대를 위한 암레스트의 길이조절 및 95° 회전 기능, 사용자 탑승 편의성을 위한 바닥까지의 시트하강 및 운행 시 승강할 수 있는 기능, 캐스터 회전반경 및 안전성 증대를 위한 발판 추가 및 풋레스트 길이 조절 기능, 승·하강 시 흔들림 방지를 위한 프레임 및 승·하강 링크 설계 등을 개선시켰다. 또한 안전주행을 위한 컨트롤러 및 드라이브 부문과 사용자 편의성 측면의 기능들을 추가적으로 설계·제작하였다. 추가 기능을 보완하여 제작된 실내 전동휠체어의 동작 상태를 평가하기 위해 구동 실험을 수행하였다. 연속 주행시간, 회전반경, 승·하강 최대 하중, 최대 승강 높이, 소음레벨, 운행 보조센서 센싱 최소거리, 서버 및 앱 프로그램 상호연동 및 기기호환성, 듀티 사이클 최대 오차율의 성능실험을 수행하였다. 실험 결과, 더 개선하여 설계·제작한 전동휠체어는 시험 목표 값을 달성하였으며, 성공적으로 동작하는 것을 확인할 수 있었다. 향후 연구로는 개선하여 제작된 이·승강 전동휠체어에 대해 사용자 측면에서의 사용성 평가를 수행할 것이다.

• 한국산학기술학회논문지
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• 제12권8호
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• pp.3579-3586
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• 2011

본 연구는 남녀 대학생들의 비만과 대사증후군 유병률을 알아보고, BMI와 대사증후군 위험인자의 관계를 비교 분석함으로써 대학생의 만성 질환 이환율을 낮추고 well-being에 대한 인식을 높이고자 한다. B광역시 P대학 건강관련 교양과목 수강생인 남녀 대학생 848명을 대상으로 BMI기준에 따라 UWG, NWG, OWG, OG로 나누어 남녀 각각 대사증후군 위험인자를 측정하였다. 총 대상자에서 비만(BMI${\geq}$25 kg/$m^2$) 유병률은 12. 61%, 과체중(BMI 23-24.9 kg/$m^2$)은 31.36%로 나타났다. 대사증후군의 위험인자가 3개 이상의 기준을 만족한 학생은 0.35%(3명), 2개만 가지고 있는 학생은 3.41%(29명)로 낮게 나타났다. 그러나 대사증후군 위험인자를 적어도 1개 가지고 있는 대상자는 29.71%(252명)로 높은 수준을 보였다. BMI와 대사증후군 위험인자에 대한 그룹간 비교를 보면, 남자 대학생의 경우 BMI가 높은 그룹이 낮은 그룹보다 glucose를 제외한 허리둘레, TG, BP에서 더 높게 나타났으며, HDL-C에서는 더 낮게 나타났다. 여자 대학생의 경우 허리둘레와 BP에서 BMI가 높은 그룹이 더 높게 나타났으며, TG, HDL, glucose에서는 그룹간 차이가 없었다.