• Journal of Microbiology and Biotechnology
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• 제25권1호
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• pp.137-142
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• 2015

Trimethoprim-sulfamethoxazole (TMP-SMX) has been used for the treatment of urinary tract infections, but increasing resistance to TMP-SMX has been reported. In this study, we analyzed TMP-SMX resistance genes and their relatedness with integrons and insertion sequence common regions (ISCRs) in uropathogenic gram-negative bacilli. Consecutive nonduplicate TMP-SMX nonsusceptible clinical isolates of E. coli, K. pneumoniae, Acinetobacter spp., and P. aeruginosa were collected from urine. The minimal inhibitory concentration was determined by Etest. TMP-SMX resistance genes (sul and dfr), integrons, and ISCRs were analyzed by PCR and sequencing. A total of 45 E. coli (37.8%), 15 K. pneumoniae (18.5%), 12 Acinetobacter spp. (70.6%), and 9 Pseudomonas aeruginosa (30.0%) isolates were found to be resistant to TMP-SMX. Their MICs were all over 640. In E. coli and K. pneumoniae, sul1 and dfr genes were highly prevalent in relation with integron1. The sul3 gene was detected in E. coli. However, in P. aeruginosa and Acinetobacter spp., only sul1 was prevalent in relation with class 1 integron; however, dfr was not detected and sul2 was less prevalent than in Enterobacteriaceae. ISCR1 and/or ISCR2 were detected in E. coli, K. pneumoniae, and Acinetobacter spp. but the relatedness with TMP-SMX resistance genes was not prominent. ISCR14 was detected in six isolates of E. coli. In conclusion, resistance mechanisms for TMP-SMX were different between Enterobacteriaceae and glucose non-fermenting gram-negative bacilli. Class 1 integron was widely disseminated in uropathogenic gram-negative baciili, so the adoption of prudent use of antimicrobial agents and the establishment of a surveillance system are needed.

• Journal of Chest Surgery
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• 제24권4호
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• pp.376-381
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• 1991

From June 1979 to July 1988 for 9 years, total 440 cases of lung cancer[including biopsy and surgical specimen] of the Pusan Paik hospital were examined for the clinical and pathology study. The findings of the study are as follows; [1] The incidence of lung cancer started to increase from 1982, and it again remarkably increased since 1987. Such increase was solely brought by the increase of male lung cancer. Male and female ratio is 5.6: 1. [2] Histopathologically, the most prevalent type is squamous cell carcinoma[60.ado], and next are adenocarcinoma[15.6%] and small cell carcinoma[15.0%]. But in female alone, the most prevalent type is adenocarcinoma[40.3%], and next are squamous cell carcinoma[37.3%] and small cell carcinoma[11.9%]. [3] The absolute number of adenocarcinoma are approximately equally distributed among both sexes until 60 years of age. Above 61 years of age, mostly male was shown while female was not. Most probably, many female patient.- of that old age simply did not visit general hospitals for surgery in Korea. [4] Surgical treatment was performed in 8% of total cases of lung cancer. And most cases showed stage I progression of the cancer. Average size of the cancer was 5 cm in diameter in the operated 35 cases suggesting that the cancer could be detected more than 10 years ago before the time of surgery. [5] Lung cancer affected more in the right lung [right: left=1.6: 1], and each upper lobe of both lungs are affected about 1/4 of cases indicating that about 1/2 of all lung cancer develop from the upper lobes. [6] There are more nonsmokers[67.6%] among the lung cancer patients[male 64.6%, female 82.1%]. Probably, this will mean that there are other potent carcinogenic agents in our environment like automobile exhaust beside tobacco smoke. For the past history of lung disease other than cancer, tuberculosis is the most prevalent disease[16.1%, male 17.4%, female 9.0%]. Most of them is probably not related etiologically though this possibility is not completely denied.

• 대한불안의학회지
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• 제10권1호
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• pp.24-29
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• 2014

Objectives : This study aimed to investigate the associations between physical disorders and prevalent/incident suicidal ideation in a community dwelling older population aged 65 years or over. Methods : 1204 people aged 65 years or over evaluated at baseline. Suicidal ideation was identified using the questions from the community version of the Geriatric Mental State Schedule ("GMS B3"). Reported physical disorders covering 11 common and generally chronic health problems were ascertained. Covariates included were depression, age, gender, years of education, accommodation status, past occupation, and current occupation. Of 1066 without suicidal ideation at baseline, 805 (76%) were followed 2 years later, and incident suicidal ideation was evaluated. Results : Prevalent suicidal ideation was significantly associated with 4 of 11 physical disorders: eyesight problems, persistent cough, heart disease and paralysis or weakness in one leg or arm. Incident suicidal ideation was associated with 3 physical disorders: asthma, high blood pressure and paralysis or weakness in one leg or arm. Both prevalent and incident suicidal ideation were significantly associated with increased number of physical disorders. Conclusions : Certain physical disorders were comorbid and precipitating factors of suicidal ideation in elders. And appropriate intervention and treatment of physical disorders might prevent suicidal ideation in elderly.

• 대한한의학회지
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• 제21권1호
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• pp.84-90
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• 2000

Background and Purpose: Stroke in young adults is relatively uncommon. Only 3.7-14.4% of all strokes occur in patients aged 15-45 years. Stroke in young adults has more various and diverse possible causes than stroke in the elderly. We studied to gain further insight into both pathogenic and etiologic determinants in young adults with stroke. Methods : We retrospectively reviewed the medical records of 230 young patients aged 15-45 years who were admitted to the 2nd internal medicine department of Kyung Hee Oriental Medical Center with a diagnosis of stroke between May 1995 and May 1999. We analysed clinical features and diagnostic tests, such as brain imaging, cerebral angiography, echocardiography, 24 hours holter monitoring and other laboratory tests. Results : 1. Of 230 young patients with stroke aged 15-45 years(176 males(76.5%) and 54 females(23.5%)), 140 patients(60.9%) showed ischemic stroke and 90 patients(39.1 %) showed hemorragic stroke. 2. The most prevalent age group was from 40 to 45 years with 142 patients(61.7%) 3. The most frequent site of 140 ischemic stroke was MCA territory in 93 cases(66.4%) and Multiple, VA territory, PCA territory, ACA territory in order of frequency. 4. The most frequent site of 90 hemorrhagic stroke was basal galglia hemorrhage 57 cases(63.3%) and subcortical 13 cases(14.5%), pons, thalmus, subarachnoid, cerebellum in order of frequency. 5. The causes of hemorrhagic stroke were hypertension 49 cases(54.5%), arteriovenous malformation 7 cases(7.8%), ruptured aneurysm 4 cases(4.5%), angioma 3 cases(3.3%). 6. The risk factors of ischemic stroke were smoking, alcohol drinking, hyperlipidemia, hypertension, obesity, heart disease, history of CVA, diabetes mellitus, in order of frequency. 7. The comparison of risk factors between ischemic and hemorrhagic stroke: hypertension was prevalent in hemorrhagic stroke, heart disease and history of CVA were prevalent in ischemic stroke. Conclusions: From the above results, we found that stroke in young adults had various possible causes. Young adults with stroke deserve an extensive but tailored evaluation which include angiography and echocardiography for diagnosis.

• 대한한방부인과학회지
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• 제28권4호
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• pp.1-10
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• 2015

Objectives : This study was performed to investigate the efficacy of Korean Medical Therapy (KMT) for patients undergoing In Vitro Fertilization (IVF). Methods : We analysed clinical data of 61 patients who visited for KMT after IVF from January 2013 to December 2013. Results : 1. Above 2years (63.9%) was the most prevalent duration of infertility. 2. The mean age of patients was 36.0 years old. The most prevalent age was 31~35 (45.9%) and 36~49 (27.9%) was next. 3. Anjonicheon-tang was the most prevalent KMT prescription, followed by Sutae-hwan, Jogyeongjongok-tang . 4. Twenty seven patients (44.3%) succeeded in pregnancy. And twenty patients (32.8%) succeeded in delivery. 5. The average duration of KMT was 73.8 days. Pregnancy success group was treated for 78.1 days, and pregnancy fail group was treated for 57.0 days. As a result, pregnancy success group was more treated than pregnancy fail group by 21.1 days in KMT. Conclusions This study suggested that KMT affects improvement of the clinical pregnancy and delivery rate in IVF.

• 한국동물위생학회지
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• 제43권3호
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• pp.113-128
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• 2020

For estimating the prevalence of bovine infectious disease agents, the pathogens were classified as follows: the digestive disease agents, respiratory disease agents, reproductive disease agents, and tick-borne disease agents. This study covered 81 published papers regarding bovine infectious diseases in Korea that determined the presence of diverse pathogens or the antibodies elicited by the infectious agents in cattle from 2010 to 2019. In total, 59,504 cows were involved in the papers reporting the causative agents in their cases. The disease prevalence for the digestive, respiratory, reproductive, and tick-borne cases was 9.0%, 13.4%, 10.4%, and 7.8%, respectively. Bovine viral diarrhea virus, Escherichia coli, Mycobacterium avium subsp. paratuberculosis, and Eimeria spp were more significantly prevalent in the cows under one-year age than over one-year age. Bovine viral diarrhea virus, Escherichia coli, Mycobacterium avium subsp. paratuberculosis, and Anaplasma spp. were more significantly prevalent in Hanwoo than dairy cattle. Coxiella burnetii, Neospora caninum, and Theilieria spp. were more significantly prevalent in dairy cattle than Hanwoo. Tick-borne disease agents were more prevalent in cows grazing than the case in housing. Our analytic data obtained from this study emphasize the need for more studies on the occurrence of these pathogens according to the breed, age, and the region, to come up with bovine infectious disease control measures in Korea.

• Clinics in Shoulder and Elbow
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• 제7권1호
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• pp.5-9
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• 2004

회전근 개 파열과 동반된 관절 내 변화의 전체빈도는 활액막염 (63%), 관절순 이상(54%), 이두박 건 활차의 이상(53%), 이두박 건 이상(41%), 상완골두(30%) 및 관절와(20%) 순 이었으며. 이두박 건 장두, 이두박 건 활차, 관절와의 관절염 변화 등의 경우 2군에서 호발하였다. 또한 수술 시 치료가 필요했던건 주 변화의 경우는 2군에서 이두박 건 활차, 골두, 관절순 및 활액막에서 빈도가 증가하였다.

• 한국식생활문화학회지
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• 제12권5호
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• pp.495-508
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• 1997

The purpose of this study is to investigate the dietary patterns and behaviors of self-boarding college students in Wonju. This survey was carried out through questionnaries and the subjects were 118 man and 145 woman students of five colleges in Wonju. The results of this study were summarized as follows: 1. The students who live in Kangwon Province, reaching 49.0% of the subjects, are the most prevalent. In the frequency of homecoming, 'twice a month' is the greatest. One-room system is the most prevalent in the self-boarding patterns. 2. 90.8% of the students have the electric rice cooking pot. Portable gas range, gas range, electric stove, in this order, are more general as cooking appliances. Specially, more than half of students, either male or female, have refrigerators. 3. 80.4% of students cook their own meal. 'once a day' in cooking frequency is the most prevalent. 4. The students, either male or female, prepare breakfast and dinner for themselves at home, and have lunch at the school cafeteria. They choose boiled rice mostly at any mealtime. 5.In the frequency of drinking, 'three times a week' in man students and 'two or three times a month' in woman students are the most prevalent. The drink shop and their own self-boarding room are most preferred as the place for drinking in the both case of male and female. 6. In the quantity of drinking of male students, 'more than three bottles of Soju', 'two bottles of Soju', and 'one bottle of Soju', in this order, are recorded more frequently and in the case of female students, comes 'one bottle of Soju' and 'one bottle of beer' in that order. 7. Male students drink to have a dim consciousness and female students to feel good. In this case there are differences. 8. After drinking in the previous night, more female students have a breakfast than male. While more female students have any kind of food, most of male students have a broth to relieve hangover or ramyun. 9. The causes for no breafast after drinking were 'rising late', 'stomachache', 'habits' in this cider. 10. After students self-examine their own health, they express their health state as 'usual', 'very healthy' 'not healthy' in this order. Most of male and female students point out the stomach as a painful part.

• 치위생과학회지
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• 제5권4호
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• pp.199-204
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• 2005

51예의 구강 백반증과 149예의 편평태선의 임상적 발현 양상을 비교 분석하고 병리조직 소견에 따른 환자 예후를 추적하여 임상적 병리조직학적 차이점을 고찰하였다. 분석 결과, 연령 분포와 성별, 임상적 특징, 환자의 임상 증상, 상피 이형성 빈도, 임상 추적 관찰 결과 재발 여부 등에 있어 차이를 나타냈다. 구강 백반증과 편평태선의 임상적인 감별점은 구강백반증의 경우 각화증을 유발한 원인, 즉 협점막과 혀의 측면부위에 가해질 수 있는 만성적 자극, 흡연 등의 원인을 제거했을 때 소실되는지의 여부, 편평태선의 경우 전형적으로 양측성 발생과 다발성 병소, 통증이나 압통, 불쾌감과 작열감 등의 증상, 동반되는 피부 병소 등을 들 수 있다. 임상 진단에서 확진을 하지 못하는 경우는 조직 생검을 통하여 최종 진단을 내릴 수 있다.

• Pediatric Infection and Vaccine
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• 제7권1호
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• pp.108-112
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• 2000

목 적 : Rotavirus와 adenovirus는 영유아에서 급성장염을 유발하는 주요 원인인데 한국에서 adenovirus에 관한 연구 논문이 적어 저자들은 최근에 발생한 adenovirus와 rotavirus 장염의 분포를 조사하여 향후 질병 예방 및 발생 정보에 도움을 얻고자 연구 분석하였다. 방 법 : 1998년 3월에서 1999년 6월까지 대상으로 건국의대 부속병원에 급성 위장관염으로 입원 또는 통원 치료를 한 143명을 대상으로 하였다. 결 과 : 전체 환아 143명중 rotavirus 양성은 53명으로 37%의 양성률을 보였으며 1999년 1월에서 3월 사이의 초봄에 가장 많이 발생하였으며 2세 이하에서 가장 많이 발생함을 보였고 2~4세 사이에서도 16%의 양성률을 보였으며 9월에 전체 24례중 6례로 가장 많이 검출되었고 2개월에서 2세 사이에 많은 발생을 보였다. Adenovirus와 rotavirus에 동시 검출된 경우는 7명(5%)이였다. 결 론 : Rotavirus 장염은 1월부터 3월에 가장 많은 발생 빈도를 보여서 겨울 및 초봄에 유행시기를 보였으며 adenovirus는 9월에 가장 많이 검출 되었다. Rotavirus와 adenovirus의 발생의 중간 나이 분포는 각각 1세 4개월, 1세 3개월의 분포를 보였다.