• Journal of Plant Biotechnology
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• 제4권3호
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• pp.129-134
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• 2002

We report the development of a new selection system for the transformation of pepper plants by mannose. In order to achieve this, we first tested several factors related to regeneration conditions. Among the 30 inbred lines examined, line P9l5 was able to generate shoots at the highest rate from both cotyledons and hyporotyls in MS media. A dosage curve for optimizing the selection conditions was established by mixing mannose (range 0-50 g/L) and sucrose (range 0-30 g/L). The least selection pressure on shoot formation was created by a mixture of sucrose and mannose at 20 g/L and 15 g/L, respectively, and the threshold for ultimate tissue death was 50 g/L of mannose irrespective of the sucrose concentration. However, we found that mannose itself was not the sole inhibitor of pepper shoot development. High concentrations of sucrose (30 g/L) contributed additively to the inhibition of shoot formation at higher mannose concentrations. Genotype preference is a major factor that enhances regeneration ability in mannose media, as was observed in MS media. P9l5 and P410 line had high regeneration rates under mannose selection conditions in the presence of Agrobacterium infection. Different virulence levels of Agrobacterium strains did change the regeneration rates, probably due to interaction with the specificities of the inbred lines. Taken together, P9l5 offers the best pepper inbred line for transformation and we recommend a selection condition of 20 g/L of sucrose and 15 g/L or more of mannose up to 50 g/L in media.

• Journal of Oral Medicine and Pain
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• 제23권4호
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• pp.433-445
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• 1998

본 연구는 정상인의 저작근에서 지속적인 등척성 수축후 근전도 power spectrum과 압력통각 역치의 회복 특성을 구명하기위해 시행되었다. 악안면 영역의 동통과 긴으장애의 벙력 및 현증이 ㅇ벗고 정상적인 교합관계를 가진 26명의 정상인(남자 14명, 여자 12명) 을 대상으로 최대근활성도의 70% 수준에서 인내가능 할 때까지의 등척성 수축과 수축후 회복기 동안의 근전도 power spectrum과 압력통각 역치를 컴퓨터를 이용한 근전도 시스텀과 전자식 압력통각계를 사용하여 분석한 결과 다음과 같은 결론을 얻었다. 1. 지속적인 등척성 수축 시작 시점의 중간주파수에서 남녀간에는 통계적으로 유의한 차이가 관철되지 않았지만, 근육간 비교에서는 전측두근에서 교근보다 유의하게 높게 나타났다(p<0.05). 2. 지속적인 등척성 수축전 암력통각 역치는 전축두근에서 교근보다 유의하게 높았고(p<0.001), 남성에서 여성보다 유의하게 높게 나타났다(p<0.05). 3. 지속적인 등척성 수축시 중간주파수와 압력통각 역치의 변화량은 성별간, 근육간에 우의한 차이가 관찰되지 않았다. 4. 지속적인 등척성 수축말기 중간주파수는 수축초기에 비하여 유의하게 감소하였으며(p<0.001), 이의 회복은 모든 근육에서 60초와 120초 사이에서 이루어 졌다. 5. 지속적인 등척성 수축후 압력통각역치는 수축전에 비해 유의하게 감소하였으며(p<0.001), 수축전 수준으로의 회복은 여자군의 전측두근과 교근에서는 30분후에 남자구느이 전측두근과 교근에서는 50분 후에 이루어졌다. 6. 지속적인 등척성 수축후 주관적인 동통이 소실된 시각은 여자군의 전축두근에서는 28분, 교근에서는 42분으로 남자군의 전측두근에서는 30분, 교근에서는 40분으로 나타났다.

• 한국산업보건학회지
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• 제10권1호
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• pp.58-73
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• 2000

Objectives : This study was performed to evaluate BTEX exposure to gas station service attendants and the critical affect of benzene and MtBE airborne concentration. Methods : the degree of exposure to airborne BTEX and MtBE was examined in the service attendants at seven gas stations across the country during a summer season. The TWAs(time-weighted averages) of atmospheric concentration of substances in personal and area samples, were calculated. The component ratio of BTEX and MtBE in the samples of bulk gasoline from each station studied was also measured. Results : The airborne concentrations of BTEX and MtBE showed a lognormal distribution and The TWA concentrations of benzene in personal samples from each station were 0.089 ppm - 0.18 ppm, and those of toluene were 0.097 ppm - 0.2 ppm. The average TWA concentrations of xylene and ethyl benzene was 0.03 ppm and 0.001 ppm, respectively. The TWA concentrations of MtBE were 0.4 ppm - 1.3 ppm. The volume concentrations of MtBE, toluene, ethyl benzene and xylene in the bulk gasoline samples were 3 - 7.4 %, 3 - 12 %, 0.64 % and 1.5 - 10 %, respectively. Conclusions : The benzene concentration was detected to exceed the ACGIH threshold benzene level of 0.5 ppm, in one of 74 personal and area samples. MtBE, a substitute for aromatic compounds such as benzene in gasoline, was found to bring about a greater chance of exposure to carcinogen, due to its high vapor pressure and carcinogenicity.

• 한국환경과학회지
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• 제16권9호
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• pp.1051-1061
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• 2007

The impact of midlatitude synoptic system (upper-level trough) on typhoon intensity change was investigated by analyzing the spatial and temporal characteristics of vertical wind shear (VWS), relative eddy momentum flux convergence (REFC), and potential vorticity (PV). These variables were computed over the radial mean $300{\sim}1,000km$ from the typhoon center by using GDAPS (Global Data Assimilation and Prediction System) data provided by the Korea Meteorological Administration (KMA). The selected cases in this study are typhoons Rusa (0215) and Maemi (0314), causing much damage in life and property in Korea. Results show that the threshold value of VWS indicating typhoon intensity change (typhoon to severe tropical storm) is approximately 15 m/s and of REFC ranges 6 to 6.5 $ms^{-1}day^{-1}$ in both cases, respectively. During the period with the intensity of typhoon class, PVs with 3 to 3.5 PVU are present in 360K surface-PV field in the cases. In addition, there is a time-lag of 24 hours between central pressure of typhoon and minimum value of VWS, meaning that the midlatitude upper-level trough interacts with the edge of typhoon with a horizontal distance less than 2,000 km between trough and typhoon. That is, strong midlatitude upper-level divergence above the edge of the typhoon provides a good condition for strengthening the vertical circulation associated with the typhoons. In particular, when the distance between typhoon and midlatitude upper-level trough is less than 1,000 km, the typhoons tend to weaken to STS (Severe Tropical Storm). It might be mentioned that midlatitude synoptic system affects the intensity change of typhoons Rusa (0215) and Maemi (0314) while they moves northward. Thus, these variables are useful for diagnosing the intensity change of typhoon approaching to the Korean peninsula.

• 대한정형도수물리치료학회지
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• 제18권1호
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• pp.57-63
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• 2012

Background: The number of old people with degenerative osteoarthritis one of the chronic disease, were constantly increased. Many researchers have made a great effort to verify the effects of ultrasound and laser therapy in degenerative osteoarthritis treatment. This study applied ultrasound-laser integration therapy on knee joint degenerative osteoarthritis and compared its effect with ultrasound and laser. Methods: We assigned 60 patients age 65 to 85 who had been diagnosed as knee joint degenerative osteoarthritis in G nursing home in Daejeon city. Randomization was done in blocks of three, holding twenty people per each group to receive either ultrasound, laser, ultrasound-laser integration therapy. This study carried out the experiment for 6 weeks to from April 17, 2010. We measured variables using visual analog scale (VAS) and pressure threshold meter (PTM) of the effects by before and after exercise. Results: It has been found that VAS was reduced and PTM was increased in all three groups. Compare with the other groups, Ultrasound-laser integration therapy group had lower VAS and higher PTM than ultrasound therapy and laser therapy group. Conclusions: These results lead us to the conclusion that ultrasound-laser integration have influenced the pain reduction of the knee degenerative osteoarthritis.

• 셀메드
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• 제4권1호
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• pp.3.1-3.8
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• 2014

Spa represents a treatment widely used in many rheumatic diseases (RD). The mechanisms by which immersion in mineral or thermal water ameliorates RD are not fully understood. The net benefit is probably the result of a combination of factors, among which the mechanical, thermal and chemical effects are most prominent. Buoyancy, immersion, resistance and temperature play important roles. According to the gate theory, pain relief may be due to the pressure and temperature of the water on skin; heat may reduce muscle spasm and increase the pain threshold. Mud-bath therapy increases plasma ${\beta}$-endorphin levels and secretion of corticotrophin, cortisol, growth hormone and prolactin. It has recently been demonstrated that thermal mud-bath therapy induces a reduction in circulating levels of prostaglandin E2, leukotriene B4, interleukin-$1{\beta}$ and tumour necrosis factor-${\alpha}$, important mediators of inflammation and pain. Furthermore, balneotherapy has been found to cause an increase in insulin-like growth factor-1, which stimulates cartilage metabolism, and transforming growth factor-${\beta}$. Beneficial anti-inflammatory and anti-degenerative effects of mineral water were confirmed in chondrocytes cultures, too. Various studies in vitro and in humans have highlighted the positive action of mud-packs and thermal baths, especially sulphurous ones, on the oxidant/antioxidant system. Overall, thermal stress has an immunosuppressive effect. Many other non-specific factors may also contribute to the beneficial effects observed after spa therapy in some RD, including effects on cardiovascular risk factors (e.g. adipokines) and changes in the environment, pleasant surroundings and the absence of work duties.

• 센서학회지
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• 제4권4호
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• pp.62-69
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• 1995

1차원 MWPC(Multiwire Proportional Chamber)를 이용한 디지탈 X-선 사진촬영장치를 개발하였다. X-선의 입사위치 정보는 각각의 양극선에 증폭기, 판별기및 계수기를 연결하여 얻는다. 각각의 판별기에는 판별전압을 독립적으로 설정하여 검출기의 계수율 균일성을 향상시켰으며 미분형비선형값은 ${\pm}4%$이었다. 노화효과를 방지하기 위하여 기체유입형으로 제작하였으며 검출기체로는 비교적 값싼 P10기체를 사용하였다. 양극선 간격이 2mm일때 검출기체의 압력을 증가시킴으로써 위치분해능이 약 1.4mm인 우수한 특성을 얻었다. 피사체를 수직방향으로 스캐닝하여 $32{\times}32$화소의 영상을 었었다.

• The Journal of Korean Physical Therapy
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• 제13권2호
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• pp.293-303
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• 2001

The purpose of this study was to determine if there were any beneficial effects of massage or microwave diathermy regarding delayed onset muscle soreness (DOMS) and indices of muscle damage. Twenty-one adult women, randomly divided in two treatment groups and a control group, performed eccentric stepping exercise with the quadriceps until exhaustion. The treatment groups additionally performed massage or microwave diathermy after the stepping exercise. Pressure pain threshold measure for DOMS and muscle enzymes in the blood were obtained before, and 0, 24, 48 and 72 hours after exercise. The results were as follows; 1. Eccentric exercise caused DOMS and elevations of muscle enzymes in the blood, with peak values exercise levels by 24 hours after exercise and GOT and CRP by 72 hours after exercise. DOMS and CK activity remained elevated 72 hours after exercise. 2. DOMS and blood muscle enzymes response to eccentric exercise were reduces by massage or micro diathermy therapy. DOMS was significantly decreased at 72 hours after exercise by massage and microwave diathermy. CK activity was significantly decreased at 72 hours after exercise by microwave diathermy. There was the significant reduction in LDH at 48 hours, GOT at 24, 48, 72 hours. and CRP at 24, 48 hours after exercise by massage and microwave diathermy. These results indicate that massage or microwave diathermy is had effect on recovery from exercise-induced muscle damage. In our's suggestion. microwave diathermy is particularly more appropriate therapeutic modality because it is more simple and economic than massage.

• 한국의학물리학회지:의학물리
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• 제11권1호
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• pp.19-27
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• 2000

본 연구에서는 평탄한 지면 위의 도로 교통소음의 전파특성을 해석하고자 점음원과 쌍극자음원을 모델로 사용하였으며, 연속 지표면 음향임피던스에 대한 초과감쇠를 실험으로 조사하였다 연구결과 수음점이 지표면 가까이 있을 때, 도로 교통소음의 전파특성은 소음 전파경로 상의 지표면 음향임피던스에 크게 영향을 받는 것을 확인하였다. 또한 진행 차량으로부터 측정한 등가에너지레벨의 거리별 감쇠값을 이용하여 등음압곡선을 해석하였다 그리고 도로 교통소음이 인체에 미치는 영향을 조사하고자 초저주파 소음에 대한 응답특성, 깊은 수면율과 잠을 깨는 비율에 대한 연속적인 교통소음의 .효과, 연령과 소음폭로등 다양한 변수에 대하여 청력손실과 청감민감도 변화 등을 고찰하였다 해석결과 과도한 소음은 일시적 청력손실의 원인이며, 폭로가 길어지거나 강력하면 영구적 청력손실의 원인이 될 수 있음을 확인하였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.543-543
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• 2013

Thin-film transistors (TFTs) based on oxide semiconductors have been regarded as promising alternatives for conventional amorphous and polycrystalline silicon TFTs. Oxide TFTs have several advantages, such as low temperature processing, transparency and high field-effect mobility. Lots of oxide semiconductors for example ZnO, SnO2, In2O3, InZnO, ZnSnO, and InGaZnO etc. have been researched. Particularly, zinc-tin oxide (ZTO) is suitable for channel layer of oxide TFTs having a high mobility that Sn in ZTO can improve the carrier transport by overlapping orbital. However, some issues related to the ZTO TFT electrical performance still remain to be resolved, such as obtaining good electrical contact between source/drain (S/D) electrodes and active channel layer. In this study, the bottom-gate type ZTO TFTs with staggered structure were prepared. Thin films of ZTO (40 nm thick) were deposited by DC magnetron sputtering and performed at room temperature in an Ar atmosphere with an oxygen partial pressure of 10%. After annealing the thin films of ZTO at $400^{\circ}C$ or an hour, Cu, Mo, ITO and Ti electrodes were used for the S/D electrodes. Cu, Mo, ITO and Ti (200 nm thick) were also deposited by DC magnetron sputtering at room temperature. The channel layer and S/D electrodes were defined using a lift-off process which resulted in a fixed width W of 100 ${\mu}m$ and channel length L varied from 10 to 50 ${\mu}m$. The TFT source/drain series resistance, the intrinsic mobility (${\mu}i$), and intrinsic threshold voltage (Vi) were extracted by transmission line method (TLM) using a series of TFTs with different channel lengths. And the performances of ZTO TFTs were measured by using HP 4145B semiconductor analyzer. The results showed that the Cu S/D electrodes had a high intrinsic field effect mobility and a low effective contact resistance compared to other electrodes such as Mo, ITO and Ti.