• Title/Summary/Keyword: Pressure force

Search Result 2,844, Processing Time 0.031 seconds

Pharmacological Actions of New Wonbang Woohwangchungsimwon Pill on Cardiovascular System (신원방우황청심원의 심혈관계에 관한 약효)

  • 조태순;이선미;김낙두;허인회;안형수;권광일;박석기;김상호;신대희
    • YAKHAK HOEJI
    • /
    • v.43 no.2
    • /
    • pp.237-250
    • /
    • 1999
  • In order to investigate the pharmacologic properties of New Wonbang Woohwangchungsimwon Pill(NSCH), effects of Wonbang Woohwangchungsimwon Pill (SCH) and NSCH were compared using various experimental models. In rat aorta, NSCH and SCH made the relaxation of blood vessels in maximum contractile response to phenylephrine (10-6 M) regardless to endothelium containing or denuded rings of the rat aorta. Furthermore, the presence of the inhibitors of NO synthase and guanylate cyclase did not affect significantly the relaxing effects of NSCH and SCH. NSCH and SCH inhibited the vascular contractions induced by acetylcholine, prostaglandin endoperoxide or peroxide in a dose-dependent manner. In conscious spontaneously hypertensive rats (SHRs), NSCH and SCH decreased significantly heart rate. These, at high doses, had a negative inotropic effects that was a decrease of left ventricular developed pressure and (-dp/dt)/(+dp/dt) in the isolated perfused rat hearts, and also decreased the contractile force and heart rate in the isolated rat right atria. In guinea-pig papillary muscle, these had no effects on parameters of action potential such as action potential amplitude (APA), $V_{max}$ and resting membrane potential (RMP) at low doses, whereas inhibitory the cardiac contractility at high doses. Furthermore, these had a significant inhibitory effects on palpitation of the heart in normotensive rats and SHRs. These had a significant inhibitory effects on palpitation of the heart in normotensive rats and SHRs. These results suggest that NSCH and SCH have weak cardiovascular effects, and that there is no significant differences between cardiovascular effects of two preparations.

  • PDF

Finite Element Analyses of Cylinder Problems Using Pseudo-General Plane Strain Elements(Planar Constraint) (유사 평면변형률 유한요소를 사용한 실린더 문제의 해석)

  • KWON YOUNG-DOO;KWON HYUN-WOOK;SHIN SANG-MOK;LEE CHAN-BOK
    • Journal of Ocean Engineering and Technology
    • /
    • v.17 no.5 s.54
    • /
    • pp.66-75
    • /
    • 2003
  • Long cylinder, subjected to internal pressure, is important in the analysis and design of nuclear fuel rod structures. In many cases, long cylinder problems have been considered as a plane strain condition. However, strictly speaking, long cylinder problems are not plane strain problems, but rather a general plane strain (GPS) condition, which is a combination of a plane strain state and a uniform strain state. The magnitude of the uniform axial strain is required, in order to make the summation of the axial force zero. Although there has been the GPS element, this paper proposes a general technique to solve long cylinder problems, using several pseudo-general plane strain (PGPS) elements. The conventional GPS elements and PGPS elements employed are as follows: axisymmetric GPS element (GA3), axisymmetric PGPS element (PGA8/6), 2-D GPS element (GIO), 3-D PGPS element (PG20/16), and reduced PGPS elements (RPGA6, RPG20/16). In particular, PGPS elements (PGA8/6, PG20/16) can be applied in periodic structure problems. These finite elements are tested, using several kinds of examples, thereby confirming the validity of the proposed finite element models.

Evaluation of suitability and stability in a skeletal Class III complete denture patient with flabby tissue: A case report (Flabby tissue를 동반하는 골격성 Class III 환자의 양악 총의치 수복 및 적합성/안정성 평가 증례)

  • Lee, Junsuk;Hong, Seoungjin;Paek, Janghyun;Noh, Kwantae;Pae, Ahran;Kim, Hyeong-Seob;Kwon, Kung-Rock
    • The Journal of Korean Academy of Prosthodontics
    • /
    • v.56 no.4
    • /
    • pp.295-301
    • /
    • 2018
  • To obtain denture retention, support, and stability in Class III edentulous cases with flat alveolar ridges and extensive flabby tissue is very difficult. The patient was a 72-year-old male who wore ill-fitting 20 year old dentures made by non-medical institutions. There was flabby tissue on the maxillary anterior ridge. The patient showed Angle Class III skeletal relationship with severe protruded mandible. First, temporary dentures were fabricated to restore the masticatory function, and final dentures were made through non- pressure impression technique and careful the arrangement of the posterior resin teeth. Improvement of the retention and stability of the denture during the occlusal force application is reported.

Development of Biomolecular Device Using Biomolecular Film Part 1: Optical Biosensor to Detect the Ethanol Using Langmuir-Blodgett Film of Eilzyme Molecules (생체분자막을 이용한 생물분자소자의 개발 제1부 :효소분자 LB막을 이용한 에탄올 측정용 광학 바이오센서)

  • 최정우;배주연지용이원홍
    • KSBB Journal
    • /
    • v.10 no.1
    • /
    • pp.105-112
    • /
    • 1995
  • The fiber-optic biosensor using enzyme-immobilized Langmuir-Blodgett film is developed fort the measurement of ethanol. The enzyme, alcohol dehydrogenase, is immobilized at the molecular level on the arachidic acid monolayer using Langmuir-Blodgett film technique. Based on the ordered multisubstrate mechanism, the immobilized enzyme kinetics is investigated. The optical sensing system is proposed, and sensor signal is proportional to ethanol concentration and is related wish the number of enzyme layers. As the number of deposited LB film layer increases up to 20 1ayers, the high ethanol concentration of 45mM can be measured without the saturation of signal. Surface pressure-area isotherm is measured for the three-different charged-lipids. Arachidic acid is the most suitable for the adsorption of alcohol dehydrogenase based on electrostatic force.

  • PDF

Soil-Reinforcement Interaction Determined by Extension Test (인장시험(引張試驗)에 의한 보강토(補强土)의 거동결정(擧動決定))

  • Kim, Oon Young
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.8 no.1
    • /
    • pp.33-40
    • /
    • 1988
  • The new technique has been used to determine the soil-reinforcement interaction. The testing apparatus is essentially a triaxial cell fitted with the capability to house a hollow cylinderical sample. A hollow cylinderical sand specimen with a concentrical layer of reinfarcing material sandwitched in the middle is used in this investigation. The reinforcement is fastened at the base. The hollow specimen can be viewed as a "unit sheet" of a soil-reinforcement composite system of infinite horizontal extent. Axial load as well as inner and outer chamber pressures can be applied to perform a test. The specimen is first subjected to an isotropic stress state corresponding to the overburden pressure. Next, an extension test by reducing the axial load is carried out. The specimen is "loaded" to failure by either the breakage of reinforcing material (tensile failure) or slippage which takes place at the soil-reinforcement interface (i.e. the overcoming of the bonding capacity). Since the reinforcement is fastened at its lower end to the base, any tendency of relative movement between the reinforcement and the sand during an extension test can induce tensile force in the reinforcement thus forming a "reversed pull-out" test condition. Preliminary test results have demonstrated positively of the new approach to test the soil-reinforcement interaction. Reinforcing elements of different extensibility were used to study the deformbility of reinforced soil. Furthermore, both the breakage and the pull-out modes of failure were observed.

  • PDF

Smart Composite Beams with Shape Memory Alloy Strips Having TWSME (2방향 형상기억효과 SMA 띠가 부착된 복합재 보의 거동)

  • Kim, Jung-Taek;Kim, Cheol;Yoon, Ji-Won
    • Proceedings of the Korean Society For Composite Materials Conference
    • /
    • 2005.04a
    • /
    • pp.51-54
    • /
    • 2005
  • Shape memory alloys (SMAs) find many applications in smart composite structural systems as the active components. Their ability to provide a high force and large displacement makes them an excellent candidate for an actuator for controlling the shape of smart structures. In this paper, using a macroscopic model that captures the thermo-mechanical behaviors and the two-way shape memory effect (TWSME) of SMAs smart morphing polymeric composite shell structures like shape-changeable UAV wings is demonstrated and analyzed numerically and experimentally when subjected to various kinds of pressure loads. The controllable shapes of the morphing shells to that thin SMA strip actuator are attached are investigated depending on various phase transformation temperatures. SMA strips start to transform from the martensitic into the austenitic state upon actuation through resistive heating, simultaneously recover the prestrain, and thus cause the shell structures to deform three dimensionally. The behaviors of composite shells attached with SMA strip actuators are analyzed using the finite element methods and 3-D constitutive equations of SMAs. Several morphing composite shell structures are fabricated and their experimental shape changes depending on temperatures are compared to the numerical results. That two results show good correlations indicates the finite element analysis and 3-D constitutive equations are accurate enough to utilize them for the design of smart composite shell structures for various applications.

  • PDF

Effects of Combustor-Level High Inlet Turbulence on the Endwall Flow and Heat/Mass Transfer of a High-Turning Turbine Rotor Cascade

  • Lee, Sang-Woo;Jun, Sang-Bae;Park, Byung-Kyu;Lee, Joon-Sik
    • Journal of Mechanical Science and Technology
    • /
    • v.18 no.8
    • /
    • pp.1435-1450
    • /
    • 2004
  • Experimental data are presented which describe the effects of a combustor-level high free-stream turbulence on the near-wall flow structure and heat/mass transfer on the endwall of a linear high-turning turbine rotor cascade. The end wall flow structure is visualized by employing the partial- and total-coverage oil-film technique, and heat/mass transfer rate is measured by the naphthalene sublimation method. A turbulence generator is designed to provide a highly-turbulent flow which has free-stream turbulence intensity and integral length scale of 14.7% and 80mm, respectively, at the cascade entrance. The surface flow visualizations show that the high free-stream turbulence has little effect on the attachment line, but alters the separation line noticeably. Under high free-stream turbulence, the incoming near-wall flow upstream of the adjacent separation lines collides more obliquely with the suction surface. A weaker lift-up force arising from this more oblique collision results in the narrower suction-side corner vortex area in the high turbulence case. The high free-stream turbulence enhances the heat/mass transfer in the central area of the turbine passage, but only a slight augmentation is found in the end wall regions adjacent to the leading and trailing edges. Therefore, the high free-stream turbulence makes the end wall heat load more uniform. It is also observed that the heat/mass transfers along the locus of the pressure-side leg of the leading-edge horseshoe vortex and along the suction-side corner are influenced most strongly by the high free-stream turbulence. In this study, the end wall surface is classified into seven different regions based on the local heat/mass transfer distribution, and the effects of the high free-stream turbulence on the local heat/mass transfer in each region are discussed in detail.

Hydrodynamic Calculation of Two-stage Weis-Fogh Type Water Turbine (2단 직렬 Weis-Fogh형 수차의 유체역학적 특성계산)

  • Ro, Ki Deok
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.41 no.11
    • /
    • pp.709-717
    • /
    • 2017
  • In this study, a model of two-stage Weis-Fogh type water turbine model is proposed, the hydrodynamic characteristics of this water turbine model are calculated by the advanced vortex method. The basic conditions and the motion of each wing are the same as that of the single-stage model previously proposed by the same author. The two wings (NACA0010 airfoils) and both channel walls are approximated by source and vortex panels, and free vortices are introduced from the body surfaces. The distance between the front wing axis and the rear wing axis, and the phase difference between the motion of the two wings, which is in phase and out of phase are set as the calculation parameters. For each case, the unsteady flow fields, pressure fields, force coefficients, and efficiency of the two wings are calculated, and the hydrodynamic characteristics of the proposed water turbine model are discussed.

Performance Evaluation of Nano-Lubricants at Thrust Slide-Bearing of Scroll Compressor (나노 윤활유를 이용한 스크롤 압축기 스러스트 베어링의 윤활특성 평가)

  • Cho, Han-Jong;Cho, Yong-Il;Cho, Sang-Won;Lee, Jae-Keun;Park, Min-Chan;Kim, Dae-Jin;Lee, Kwang-Ho
    • Journal of the Korean Society for Precision Engineering
    • /
    • v.29 no.1
    • /
    • pp.121-125
    • /
    • 2012
  • This paper presents the friction and anti-wear characteristics of nano-oil with a mixture of a refrigerant oil and carbon nano-particles in the thrust slide-bearing of scroll compressors. Frictional loss in the thrust slide-bearing occupies a large part of total mechanical loss in scroll compressors. The characteristics of friction and anti-wear using nano-oil is evaluated using the thrust bearing experimental apparatus for measuring friction surface temperature and the coefficient of friction at the thrust slide-bearing as a function of normal loads up to 4,000 N and rotating speed up to 3,200 rpm. It is found that the coefficient of friction increases with decreasing rotating speed and normal force. The friction coefficient of carbon nano-oil is 0.023, while that of pure oil is 0.03 under the conditions of refrigerant gas R-22 at the pressure of 5 bars. It is believed that carbon nano-particles can be coated on the friction surfaces and the interaction of nano-particles between surfaces can be improved the lubrication in the friction surfaces. Carbon nano-oil enhances the characteristics of the anti-wear and friction at the thrust slide-bearing of scroll compressors.

Generation mechanisms of coastal low level jets associated with baroclinicity along the Texas Gulf coast (텍사스 연안의에 의한 연안저층 제트의 생성 역학)

  • ChoiHyo
    • 한국해양학회지
    • /
    • v.20 no.2
    • /
    • pp.28-39
    • /
    • 1985
  • The driving mechanisms for low level jets(LLJ) and coastal surface maximum winds are studied with observed wind data from June, 1976 through August, 1980 at Port Aransas and Victoria, Texas, in connection with a baroclinic model. This model is developed considering the forcing functions such as the synoptic and meso-scale pressure gradient, the frictional force, and the atmospheric stability. The results show that a LLJis observed on over 95% of the occasions when a nighttime coastal wind maximum occurred. Baroclinicity generated by sloping terrain during the summertime causes the diurnal variation in the thermal field. This thermal wind component would then decrease the prevailing synoptic-scale southerly wind by day and allow it to increase at night. Nighttime atmospheric stability leads to frictional decoupling which enhances the nocturnal LLJ. At the coastal site neutral stability prevails, thus all owing downward transfer of momentum from the nocturnal LLJ and results in the nocturnal coastal surface wind maximum. The height of LLJis not uniquely related to the inversion layer, and the results of the computations using this model show a good agreement with the observations.