• Biomolecules & Therapeutics
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• v.28 no.2
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• pp.163-171
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• 2020

Silibinin exhibits antidiabetic potential by preserving the mass and function of pancreatic β-cells through up-regulation of estrogen receptor-α (ERα) expression. However, the underlying protective mechanism of silibinin in pancreatic β-cells is still unclear. In the current study, we sought to determine whether ERα acts as the target of silibinin for the modulation of antioxidative response in pancreatic β-cells under high glucose and high fat conditions. Our in vivo study revealed that a 4-week oral administration of silibinin (100 mg/kg/day) decreased fasting blood glucose with a concurrent increase in levels of serum insulin in high-fat diet/streptozotocin-induced type 2 diabetic rats. Moreover, expression of ERα, NF-E2-related factor 2 (Nrf2), and heme oxygenase-1 (HO-1) in pancreatic β-cells in pancreatic islets was increased by silibinin treatment. Accordingly, silibinin (10 μM) elevated viability, insulin biosynthesis, and insulin secretion of high glucose/palmitate-treated INS-1 cells accompanied by increased expression of ERα, Nrf2, and HO-1 as well as decreased reactive oxygen species production in vitro. Treatment using an ERα antagonist (MPP) in INS-1 cells or silencing ERα expression in INS-1 and NIT-1 cells with siRNA abolished the protective effects of silibinin. Our study suggests that silibinin activates the Nrf2-antioxidative pathways in pancreatic β-cells through regulation of ERα expression.

• Journal of Food Hygiene and Safety
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• v.1 no.1
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• pp.107-113
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• 1986

It is estimated that the loss of Korean agricultural and fishery products during the storage period is usually more than 20%, and it is difficult to increase agricultural products by a 10% annual rate directly. Therefore, development of food preservation techniques has now become a most important atternative for the indirect increase of such products and for its senitary distribution. Changes eating habits and improved living conditions have accelerated the demand for convenience food production and for this reason it is essential that raw materials at stable, resonable prices and hygienic quality be available the year round. At the end of 1980, the Korean government conceded th economical feasibility of the storage of foods by irradiation and a procedure for preserving food by irradiation on a batch scale was successfully developed by KAERI in 1982. Based on the research results accomplished by the KAERI and on the recommendation on wholesomeness of irradiated food by Joint Committee of FAO/IAEA/WHO in 1980, the approval of wholesomeness of irradiated food was declared by presidential decree in June 1985 and the procedure of permission for individual items is in progress. Korean private firms (Ryung Young Co.) which was technically assisted by KAERI for five years have taken mush interest in the establishment of such facilities in Korea, therefore Ryung Young Co. had proposed for the construction of 500 Kci Co-60 irradiator to the Ministry of Science and Technology in July 1984. The permission of construction has approved by government in May 1985. The commercial irradiator will be constructed as one of the most modernized facilities until May 1987 and that facilities will contribute the propagation of commercial storage of foods and its hygienic quality.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.41 no.4
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• pp.73-81
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• 2009

The document archives like official documents, books, maps and historic paper artifacts are primarily based on the organic cellulosic materials. As the passage of time, these organic cellulosic materials are slowly deteriorated by various aging factors, like light, polluted air and biological fungi. Many researchers have been carried out the examination method of deteriorating origins, the mechanism of aging hysteresis, and the preserving method of archival materials. One of the most simple and easiest ways for conservation of organic archival documents is the proper storage under environmental control. Corrugated board for archival quality container has been developed and already used in advanced country, like Japan, USA, German, UK and Europe. In case of Korea, corrugated board for archival quality container has been used a decade ago, but totally imported. This study was tried to develop the corrugated board for archival quality container. Liner and corrugated medium were specially produced and finally manufactured to E flute corrugated board. The physical and strength properties of permanent base paper and corrugated board were evaluated, and compared with imported corrugated board. 4 kinds of corrugating adhesives were considered various in order to investigate optimum adhesive for flute development between liner and corrugating medium, and evaluate adhesion strength under conditions of storage and curing temperatures.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.12
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• pp.1782-1789
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• 2016

This study evaluated the effect of vacuum and modified atmosphere (40% $CO_2+60%$ $N_2$, MA) packaging on the chemical composition, physicochemical properties and sensory attributes of chill-stored meat from 10 fallow deer (Dama dama) bucks at 17 to 18 months of age. The animals were hunter-harvested in the forests of north-eastern Poland. During carcass dressing (48 to 54 h post mortem), both musculus longissimus muscles were cut out. Each muscle was divided into seven sections which were allocated to three groups: 0, A, and B. Samples 0 were immediately subjected to laboratory analyses. Samples A were vacuum-packaged, and samples B were packaged in MA. Packaged samples were stored for 7, 14, and 21 days at $2^{\circ}C$. The results of the present study showed that the evaluated packaging systems had no significant effect on the quality of fallow deer meat during chilled storage. However, vacuum-packaged meat samples were characterised by greater drip loss. Vacuum and MA packaging contributed to preserving the desired physicochemical properties and sensory attributes of meat during 21 days of storage. Regardless of the packaging method used, undesirable changes in the colour, water-holding capacity and juiciness of meat, accompanied by tenderness improvement, were observed during chilled storage.

• Journal of the Korea Society of Computer and Information
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• v.12 no.3
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• pp.131-136
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• 2007

This paper proposes a new approach to eliminate the reflectance component for the detection of text in color images. Color images, printed by color printing technology, normally have an illumination component as well as a reflectance component. It is well known that a reflectance component usually obstructs the task of detecting and recognizing objects like texts in the scene, since it blurs out an overall image. We have developed an approach that efficiently removes reflectance components while preserving illumination components. We decided whether an input image hits Normal or Polarized for determining the light environment, using the histogram which consisted of a red component. We were able to go ahead through the ability to extract by reducing the blur phenomenon of text by light because reflection component by an illumination change and removed it and extracted text. The experimental results have shown a superior performance even when an image has a complex background. Text detection and recognition performance is influenced by changing the illumination condition. Our method is robust to the images with different illumination conditions.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.5 no.4
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• pp.286-290
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• 2005

We consider the poisson equation where the functions involved are periodic including the solution function. Let $R=[0,1]{\times}[0,l]{\times}[0,1]$ be the region of interest and let $\phi$(x,y,z) be an arbitrary periodic function defined in the region R such that $\phi$(x,y,z) satisfies $\phi$(x+1, y, z)=$\phi$(x, y+1, z)=$\phi$(x, y, z+1)=$\phi$(x,y,z) for all x,y,z. We describe a very simple method for solving the equation ${\nabla}^2u(x, y, z)$ = $\phi$(x, y, z) based on the cubic spline interpolation of u(x, y, z); using the requirement that each interval [0,1] is a multiple of the period in the corresponding coordinates, the Laplacian operator applied to the cubic spline interpolation of u(x, y, z) can be replaced by a square matrix. The solution can then be computed simply by multiplying $\phi$(x, y, z) by the inverse of this matrix. A description on how the storage of nearly a Giga byte for $20{\times}20{\times}20$ nodes, equivalent to a $8000{\times}8000$ matrix is handled by using the fuzzy rule table method and a description on how the shape preserving property of the Laplacian operator will be affected by this approximation are included.

• Korean Journal of Environment and Ecology
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• v.21 no.5
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• pp.442-448
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• 2007

This study was carried out to assess the improved aspects of ecological conditions in a small stream, where eco-technological restorations such as gabion-crib mattress arrangement and soil-arresting wicker fence work had already been made up to stabilize the physically and ecologically damaged streambank. Six metrics by diatoms including species richness, Shannon diversity, saprobic index by DAIpo, percent sensitive diatoms, percent of Achnanthes minutissima, dominant index were analysed to assess the ecological integrity of small stream. By generalizing the changed values of six metrics on the stream flow from upper point(ST.1) to lower point(ST.3), it was found that the effect value of ecological condition improvement went up to as much as 33.9% on the average. The results suggested that eco-technological restoration treatment applied to this study is considerably effective for preserving the ecological integrity of small stream.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.5
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• pp.1117-1124
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• 2018

Contrast enhancement plays an important role in various computer vision systems, since their usability can be improved with visibility enhancement of the images affected by weather and lighting conditions. This paper introduces a histogram modification algorithm that reflects the properties of original images in order to eliminate the saturation effect and washed-out of image details due to the over-enhancement. Our method modifies the original histogram so that an additive term fill histogram pits and the gamma correction suppresses histogram spikes. The parameters for the additive term and gamma correction are adjusted automatically according to statistical properties of the images. Experimental results for various low contrast and hazy images demonstrate that the proposed contrast enhancement improves visibility and reduces haze components effectively, while preserving the characteristics of original images, than the conventional methods.

• Journal of Biosystems Engineering
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• v.41 no.4
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• pp.389-395
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• 2016

Purpose: Drying is one of the most widely used methods for preserving agricultural products or food. The main purpose of drying agricultural products is to reduce their water content for minimizing microbial spoilage and deterioration reaction during storage. Methods: Although numerous drying methods are successfully applied to dehydrate various agricultural products with little drying time, the final quality of dried samples in terms of appearance and shape cannot be guaranteed. Therefore, based on published literature, this review was conducted to study the drying characteristics of various agricultural products when different drying methods were applied. Results: An increase in the drying power of sources-for example, increase in hot air temperature or velocity, infrared or microwave power-and the combination of drying power levels can reduce the drying time of various agricultural products. In addition, energy efficiency in drying significantly relies on the compositions of the dried samples and drying conditions. Conclusions: The drying power source is the key factor to control entire drying process of different samples and final product quality. In addition, an appropriate drying method should be selected depending on the compositions of the agricultural products.

• The KIPS Transactions:PartD
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• v.16D no.4
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• pp.497-506
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• 2009

The method of effectively merging XML documents becomes necessary, as the use of XML is popular and the collaborative editing is required in the areas such as office documents and scientific documents editing works. As a solution to this problem, in this paper we present a theoretical framework for merging individual editing works by muli-users to a same source document. Different from existing approaches which merge documents themselves when they are merged, we represent editing works with a series of edit operations applied to a source document, which is called a edit script, merge those edit scripts by multi-users, and apply the merged one to the source document so that we can achieve the same effect of merging documents. In order to do this, assuming edit scripts based on insertion and deletion edit operations, we define notions such as static edit scripts, the intervention between edit scripts and the conflict between the ones, then propose the conflict conditions between edit scripts and the method of adjusting edit scripts when merged. This approach is effective in reducing network overhead in distributed environments and also in version management systems because of preserving the semantics of individual editing works.