• 동의생리병리학회지
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• 제27권3호
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• pp.273-279
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• 2013

The objective of this study is to find out a reason why prescriptions have different effects on each patient who has same symptoms or same abdominal examinations and further more to classify the formulas more efficiently. In applying 's prescriptions, it is known that conventional ways such as treatment in accordance with symptoms or abdominal examinations have many advantages and problems reversely. To make up for the problems, additional references like strength of constitutional resistance and location of disease, degree of income and outgo are designed. And the notion in Oriental Medicine embracing aspects mentioned above corresponds to triple energizer. Triple energizer's exuberance-debilitation is able to draw an inference from some factors like density of skin interstices, elasticity of abdomen, appetite, digestive power. According to Exuberance-Debilitation of Triple Energizer, can be divided into five steps: weak(弱)-moderately weak(中弱)-neither weak nor strong(中)-moderately strong(中强)-strong(强). prescriptions would be dealt with those 5 steps, and it would be highly effective and consequently side effects could be reduced. On the basis of this classification method upon formula group, the prescriptions of can be applied more accurately by setting a direction through strength of constitutional resistance and location of disease and combining with existing references like symptoms, palpation and abdominal examinations.

• 한국한의학연구원논문집
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• 제15권3호
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• pp.1-10
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• 2009

Samhwajahyangyakbang, a medical book of Hyangyak which was presumed to be published by Samhwaja in the late Goryeo dynasty, became the original source of Hyangyakganibang. As Hyangyakganibang became the original source of Hyangyakjesengjipseongbang which was supplemented to be Hyangyakjipseongbang, Samhwajahyangyakbang is a fundamental book which is the original source of Hyangyak medical books such as Hyangyakganibang and Hyangyakjipseongbang in the late Goryeo and the early Chosun dynasty. I restored the articles of Samhwajahyangyakbang, mainly focusing on the remaining articles in Hyangyakjipseongbang, followed by supplementing some other remaining articles with the help of , a database of old medical books, and then, recorded and discussed the results in the paper. 1. The remaining articles of Samhwajahyangyakbang were found in Hyangyakjipseongbang, Uibo and Uibanghappyeon. Among them, there is a prescription which is not overlapped in Uibanghappyeon. 2. The classification system of Hyangyakjipseongbang was alternatively adopted due to the absence of classification or table of contents in Samhwajahyangyakbang. 3. There are a total number of 152 articles in the restored Samhwajahyangyakbang and 151 articles out of the total number have been restored from Hyangyakjipseongbang. There are 5 articles which remain as notes in the citations of other books in Hyangyakjipseongbang. 4. There are a total number of 246 prescriptions in the restored Samhwajahyangyakbang. 5. Even though Samhwajahyangyakbang is a concise medical book, it is one of the core medical books which are cited in Hyangyakjipseongbang. In addition, it is the most frequently cited in Hyangyakjipseongbang among the Korean medical books. It implies that the compilers of Hyangyakjipseongbang considered Samhwajahyangyakbang the most valuable book among the Hyangyak medical books. It is speculated that such results could be achieved because Samhwajahyangyakbang was very popular in those days and its' printing quality was also good. On the contrary, the number of citations of Hyangyakgugeupbang is much less than that of Samhwajahyangyakbang. It is presumed that Hyangyakgugeupbang could not be distributed widely not because it was less valuable but because its' printing quality was poor.

• 한국융합학회논문지
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• 제12권3호
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• pp.53-59
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• 2021

의약품 정보검색 서비스를 사용할 때 대표적인 검색방법은 ATC(Anatomic Therapeutic Chemical Classification) 코드를 사용하는 것이다. 기존의 ATC코드 기반 의약정보 검색은 주요 성분이 한가지인 단일제 검색에는 매우 유용하다. 하지만 복합제의 경우에는 검색 오류가 종종 발생하고 있다. 이 문제의 원인은 ATC코드 기반 검색은 단일제 ATC 코드를 패턴매칭하여 진행 된다는 것이다. 본 연구는 ATC코드기반 검색 시 주성분을 기준으로 복합제를 검색하는 요구사항 시나리오를 분석하여 ATC코드기반 매핑 스키마를 설계하였다. ATC코드기반 매핑 스키마는 복합제의 ATC코드와 복합제에 포함된 모든 단일제의 ATC코드를 저장한 스키마를 의미한다. 이 스키마를 사용한 ATC코드기반 검색은 단일제의 주성분으로 복합제를 검색하므로 기존 방법보다 높은 정확도를 가진다. ATC코드기반 매핑 스키마는 의사의 환자 처방 효율을 높일 수 있고 의약품 안전 사용 서비스의 정확도를 올릴 수 있을 것으로 기대된다.

• 디지털융복합연구
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• 제11권9호
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• pp.289-299
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• 2013

본 연구의 목적은 현재 질병관리본부에서 사용하고 있는 건강보험 청구자료 기반의 결핵환자 분류기준을 고도화하여 보다 효과적인 결핵환자감시체계의 토대를 제공하기 위해 수행되었다. 이를 위해 건강보험심사평가원의 2009년 1년간 결핵상병으로 청구된 81,199명 중 10%인 8,118명을 표본추출한 후 실제 결핵환자인지에 대해서 의무기록 조사를 실시하여 조사가 완료되고, 국민건강보험공단 건강보험청구 자료와 매칭이 완료된 7,132명을 최종 분석대상자로 하였다. 결핵환자분류를 위한 모형을 개발하여 평가한 결과 결핵과 관련된 임상전문가 의견과 통계적 분류 알고리즘이 종합적으로 고려된 의사결정나무모형이 가장 우수한 모형으로 평가되었다. 의사결정나무 모형에 따른 결핵분류모형의 주요 독립변수는 연령, 최초 청구시점의 결핵약제 종류수, 최초 청구시점의 이용 의료기관 유형, 최초 청구시점의 청구결핵검사 종류, 2008년 결핵약 투약일수, 최초 청구시점 결핵약제 투약일수, 최초 청구시점 결핵상병 종류로 나타났다. 이 모형의 향상도는 최고 11.8이였으며, 개발된 모형에서 분류된 1~5유형까지 적용하여 청구된 자료 중 결핵이 아님을 예측할 경우, 민감도는 90.6%, 양성예측도는 96.1%, 정분류율은 87.6%로 나타나, 현재 질병관리본부에서 사용하는 청구2회 이상, 약제 2제 이상 모형(민감도 82.6%, 양성예측도 95%, 정분류율 80%)보다 우수한 모형인 것으로 나타났다.

• 한국임상약학회지
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• 제20권3호
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• pp.262-267
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• 2010

Therapeutic duplication of prescriptions is the most frequently reported inappropriate drug use in Korea. To prevent significant problems during drug prescribing and dispensing, prospectively, development of standard including drug lists considered as therapeutic duplications for the prioritized drug classes first would be necessary. This study was aimed to analyze frequent drug classes of therapeutic duplications by healthcare providers in clinical practice settings. National health claims data for drug review and reimbursement (1,426,065 prescriptions dated March 19, 2008) were analyzed. Therapeutic duplication was defined as the prescription including more than 2 ingredients belonging to the same KFDA drug classification numbers that considered to have therapeutic similarities. The following 3 drug classes were mostly frequent therapeutic duplication classes: 114 anti-pyretics, analgesics and anti-inflammatory drugs; 117 drugs for psycho-nervous system; 141 Antihistamines. About 3.5% of overall prescriptions analyzed showed therapeutic duplications. This result might be starting step to develop DUR therapeutic duplication standard.

• 대한한방내과학회지
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• 제21권1호
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• pp.55-64
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• 2000

Objectives : this project is to find the developmental possibility of medialcohol theraphy Methods : the investigation was made by finding older oriental medicine books about the medialcohol threraphy from QuinHan Dynasty to this current published Results ; in the QinHan Dynasy. the using was so popular and various in the medicine part at the Han Dynasty especially. in the BeiWei dynasty, the making method, experience and principle was very detailed in records. new medialcohol appeared besides the making method, maintenance and development of the medialcohol before the Tang Dynasty. and the taking method was also presented at that time. in the Song Dynasty, the kinds and practical applications were magnified exactly. the treatment by medialcohol was applicated in various parts. in the MingQing Dynasty, so many doctors maintained the elder doctor, experiences and created the new prescription about the medialcohol Conclusions: the effective results were shown the possibility of development in the classification result about the medialcohol for the longevity and invigoration effect and for the antitumor effect and for antistroke effect.

• 한국임상약학회지
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• 제15권2호
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• pp.127-138
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• 2005

This is to examine the OTC regulatory system of Korea in comparison with those of Japan, UK and US, and suggest the possible regulatory actions to harmonize it to international standards. Individual countries have their own regulatory requirements and processes far OTC application based on established drug monographs and safety profiles from clinical experiences. Categories of OTC drug monographs are being expanded with transparent establishment procedure according to detailed guidelines, and public opinions as well as professional experts for assessing appropriateness of wide usage without physician's prescription. In line with trend of self-medication worldwide, the number of OTC drugs is increasing and more efficient and professional drug review is underway in the separate OTC division in regulatory agency. For improving OTC regulatory system in Korea, settlement of optimal drug classification policy and management for encouraging OTC drug use, development of more detailed and specific guidelines for OTC drug application, expansion of OTC drug monographs, transparent process for OTC monographs establishment, and establishment of OTC division in health authority, are suggested.

• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 2006년도 춘계학술대회
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• pp.327-335
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• 2006

Case Based Reasoning (CBR) has come to be considered as an appropriate technique for diagnosis, prognosis and prescription in medicine. However, canventional CBR has a limitation in that it cannot incorporate asymmetric misclassification cast. It assumes that the cast of type1 error and type2 error are the same, so it cannot be modified according ta the error cast of each type. This problem provides major disincentive to apply conventional CBR ta many real world cases that have different casts associated with different types of error. Medical diagnosis is an important example. In this paper we suggest the new knowledge extraction technique called Cast-Sensitive Case Based Reasoning (CSCBR) that can incorporate unequal misclassification cast. The main idea involves a dynamic adaptation of the optimal classification boundary paint and the number of neighbors that minimize the tatol misclassification cast according ta the error casts. Our technique uses a genetic algorithm (GA) for finding these two feature vectors of CSCBR. We apply this new method ta diabetes datasets and compare the results with those of the cast-sensitive methods, C5.0 and CART. The results of this paper shaw that the proposed technique outperforms other methods and overcomes the limitation of conventional CBR.

• 제3의학
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• 제1권1호
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• pp.37-44
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• 1996

This study has surveyed the problems raised through the standardization process of differentiation system and searched its solution, reaching the following conclusion. 1. The most serious problem is, most frequently occurred, an wilful application of differentiation system or constitutive classification for disease. 2. To overcome this wilfulness, we must make a definite understanding of the origin and its applicative limit of the theory. 3. And it must be preceded for a correct and objective differentiation to standardize in all choice of the differential diagnostics and its applicative condition. 4. To establish such a corresponding diagnostic scheme, it must be generally agreed on an individuality and inevitability of the suitability to differentiation principles. 5. And, though we can make a prescription through the frequency, degree, and clarified cause of the symptom, its flexibility of application must not be necessarily, ignored. 6. As this study for standardizing the disharmony between liver and pancreas(肝脾不調) shows, accordingly, we must begin by scrutinizing and defining what the chief cause, head, and inevitable symtoms are and discern them from its affinities, making necessarily a great deal attention to minute feelings and degree about its individual symptoms. On the ground of these recognition, we must go further to establish a general standardization and try to get a specific study series.

• 대한한의학회지
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• 제17권2호
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• pp.58-72
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• 1996

I. PURPOSE AND SIGNIFICANCE OF RESEARCH The presentation of research direction for compositive study and application of oriental medicine is urgently demanded. Since there is few investigation for the interest in basic and clinical field of oriental medicine, and we hope that compositive study and concentrative research between instruction in college and local clinics is established by this research. II. RESEARCH CONTENT ${\cdot}$ Analysis of survey in basic field of oriental medicine as instruction curriculum. ${\cdot}$ Analysis of survey in clinical field of oriental medicine as the classification of disease. III. RESULT The result of investigation shows that the most interested field is acupuncture and moxibustion in clinical field and diagnostics in basic field of oriental medicine. And oriental medicinal clinic doctors are concerned about prescription and a newly-developed techniques such as new acupuncture therapy, new machines. They hope that a study of oriental medicine in clinical field be accomplished with the special clinics as leader. According to the previous results, we can work out the foundation of compositive study and concentrative research between instruction in college and local clinics, and on this ground it is considered that we can grope for the presentation of research direction of local clinics.