• 무역상무연구
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• 제69권
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• pp.327-348
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• 2016

Under the Korean legal system, as an actual carrier is not the contractual party to the contract for carriage of goods by sea, it has been tortiously liable for the damage to, or loss of cargo, should there be the negligence by its part. However, the Rotterdam Rules introduces a revolutionary liability regime for the actual carrier. According to the Rotterdam Rules, the liability of the actual carrier is same with that of a contractual carrier with the result that a shipper is entitled to bring the direct action to the actual carrier, as well as the contractual carrier on the same basis. Nevertheless, it is expected to take long time for the new approach in respect of actual carrier's liability to be confirmed by many countries, and furthermore most of shipping countries including Korea still adopt the Hague-Vis by Rules where the shipper is not allowed to bring the direct action to the actual carrier. This study reviews on whether or not the alteration of actual carrier's liability based on Rotterdam Rules would be reasonable, considering the current Korean legal system. Furthermore, this study, whilst recognizing that the overall introduction of the new liability regime is somewhat premature, suggests the imposition of contractual liability to the actual carrier from a long-term perspective. Having in mind that the article 809 of the Korean Commercial Act allows the shipper to bring the direct action to the shipowner only in the case that a time charterer is the contractual carrier, this study explores a method to apply the contractual liability to the actual carrier in the case that a slot charterer or freight forwarder is the contractual carrier, in order to establish the uniform liability system.

• 융합보안논문지
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• 제14권7호
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• pp.75-84
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• 2014

예방 의료에서 유비쿼터스 헬스케어는 노인 환자들의 수명연장에 대한 연구로 발전되고 있다. 이와 같은 연구들은 수명 연장 및 불의의 사고를 예방하기 위하여 모바일과 무선센서 기술을 사용하여 삶의 질을 향상 시켜 수명을 연장시키고 있다. 그러나 인터넷을 통해 유비쿼터스 헬스케어 응용프로그램이 모바일화 및 보급이 용이해짐에 따라 u-헬스정보 보호와 보안에 대한 위협이 증가하고 관심을 받고 있다. 따라서 본 논문에서는 보안 헬스 정보 교환 기술을 적용한 온톨로지를 이용하는 유헬스 케어 어플리케이션의 지식기반 상황인식 서비스 프레임워크를 제안한다. 본 연구에서는 유비쿼터스 컴퓨팅 환경에서 상황 영역의 보안 헬스 정보 교환 기술을 적용한 온톨로지를 위한 보편적인 어플리케이션 영역에서 상황 추론, 상황 모델링, 지식 기반 지원을 적용하는 것이다. 본 논문에서는 예방 서비스 질 변화를 위한 모바일 웹서비스, 상황 기술, 지식베이스에 대하여 논의한다.

• 대한한의학회지
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• 제17권2호
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• pp.405-417
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• 1996

An amenorrhoea means the pathologic condition that menstruation stops before the post menopausal period. Clinically, this is classified to both primary amenorrhoea and secondary amenorrhoea. Primary amenorrhoea indicate what has no first menstruation until 14 without secondary sexual sign or what has no first menstruation until 16 with secondary sexual sign before the time. Secondary amenorrhoea is diagnosised when a women with normal menstrual cycle before the onset doesn't have a menstruation over 6 months or appeals amenorrhoea for three times of her normal menstrual cycle. This clinical study was done on the patients who had come to gynecology department of oriental Hospital of Kyung Hee Medical Center from August 1, 1994 to July 31, 1995, complaining of amenorrhoea. The results obtained were as follows: 1. The amenorrhoea patient rate among outpatients who came to the deptment of gynecology was 3.4%. 2. The ratio between primary amenorrhoea and secondary amenorrhoea was 1 : 6.5. 33. The patient rate via other hospitals was 75% and Unremarkable finding(47.6%) was most numerous according to other hospital's diagnosis and hyperprolactinemia(11.9%), premature menopause(11.9%) were the second numerous diagnosis. 4. Unremarkable history(56.7%) was most numerous and among history, the fast(weight loss; 30%) was most numerous. 5. The most general symptom of amenorrhoea patient was indigestion(51.7%). 6. The most frequently used prescribtion for non-insurance was Onpojongoktang(溫胞種玉湯 ; 55%), for insurance was Gamisoyosan(加味逍遙散 ; 16.7%). 7. 25% patient show menstruation in their therapy and among this, 80% patient show menstruation within 40 days. 8. 26.9% secondary amenorrhoea patient show menstruation in their therapy and only one primary amenorrhoea patent(12.5%) shows the same result. 9. Among the effective used prescribtion, Onpojongoktang(溫胞種玉湯 ; 46.7%) is most numerous.

• Clinical and Experimental Pediatrics
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• 제63권8호
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• pp.284-290
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• 2020

Korea currently has the world's lowest birth rate but a rapidly inreasing number of preterm infants. The Korean Neonatal Network (KNN), launched by the Korean Society of Neonatology under the support of Korea Centers for Disease Control, has collected population-based data for very low birth weight infants (VLBWIs) born in Korea since 2013. In terms of the short-term outcomes of VLBWIs born from 2013 to 2016 registered in the KNN, the survival rate of all VLBWIs was 86%. Respiratory distress syndrome and bronchopulmonary dysplasia were observed in 78% and 30% of all VLBWIs, respectively. Necrotizing enterocolitis occurred in 7%, while 8% of the VLBWIs needed therapy for retinopathy of prematurity in the neonatal intensive care unit (NICU). Sepsis occurred in 21% during their NICU stay. Intraventricular hemorrhage (grade ≥III) was diagnosed in 10%. In terms of the long-term outcomes for VLBWIs born from 2013 to 2014 registered in the KNN, the post-discharge mortality rate was approximately 1.2%-1.5%, mainly owing to their underlying illness. Nearly half of the VLBWIs were readmitted to the hospital at least once in their first 1-2 years of life, mostly as a result of respiratory diseases. The overall prevalence of cerebral palsy was 6.2%-6.6% in Korea. Bilateral blindness was reported in 0.2%-0.3% of VLBWIs, while bilateral hearing loss was found in 0.8%-1.9%. Since its establishment, the KNN has published annual reports and papers that facilitate the improvement of VLBWI outcome and the formulation of essential healthcare policies in Korea.

• Journal of Electrical Engineering and Technology
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• 제9권1호
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• pp.15-26
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• 2014

This paper proposes a Modified Particle Swarm Optimization with Time Varying Acceleration Coefficients (MPSO-TVAC) for solving economic load dispatch (ELD) problem. Due to prohibited operating zones (POZ) and ramp rate limits of the practical generators, the ELD problems become nonlinear and nonconvex optimization problem. Furthermore, the ELD problem may be more complicated if transmission losses are considered. Particle swarm optimization (PSO) is one of the famous heuristic methods for solving nonconvex problems. However, this method may suffer to trap at local minima especially for multimodal problem. To improve the solution quality and robustness of PSO algorithm, a new best neighbour particle called 'rbest' is proposed. The rbest provides extra information for each particle that is randomly selected from other best particles in order to diversify the movement of particle and avoid premature convergence. The effectiveness of MPSO-TVAC algorithm is tested on different power systems with POZ, ramp-rate limits and transmission loss constraints. To validate the performances of the proposed algorithm, comparative studies have been carried out in terms of convergence characteristic, solution quality, computation time and robustness. Simulation results found that the proposed MPSO-TVAC algorithm has good solution quality and more robust than other methods reported in previous work.

• Journal of Crop Science and Biotechnology
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• 제10권3호
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• pp.147-158
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• 2007

Xanthomonas axonopodis pv. glycines(Xag) is a pathogen that causes bacterial leaf pustule(BLP) disease in soybeans grown in Korea and the southern United States. Typical and early symptoms of the disease are small, yellow to brown lesions with raised pustules that develop into large necrotic lesions leading to a substantial loss in yield due to premature defoliation. After Xag infects PI 96188, only pustules without chlorotic haloes were observed, indicating the different response to Xag. To identify differentially expressed genes prior to and 24 hr after Xag inoculation to PI 96188 and BLP-resistant SS2-2, an oligonucleotide macroarray was constructed with 100 genes related to disease resistance and metabolism from soybean and Arabidopsis. After cDNAs from each genotype were applied on the oligonucleotide macroarrays with three replicates and dye swapping, 36 and 81 genes were expressed as significantly different between 0 hr and 24 hr in PI 96188 and SS2-2, respectively. Six UniGenes, such as the leucine-rich repeat protein precursor or 14-3-3-like protein, were selected because they down-regulated in PI 96188 and up-regulated in SS2-2 after Xag infection, simultaneously. Using tubulin and cDNA of Jangyeobkong(BLP-susceptible) as controls, the oligonucleotide macroarray data concurred with quantitative real-time RT-PCR(QRT RT-PCR) results in most cases, supporting the accuracy of the oligonucleotide macroarray experiments. Also, QRT RT-PCR data suggested six candidate genes that might be involved in a necrotic response to Xag in PI 96188.

• Neonatal Medicine
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• 제16권2호
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• pp.234-238
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• 2009

출혈 후 수두증은 미숙아에서 발생하는 주요한 합병증 중 하나이다. 저자들은 출혈 후 수두증을 가진 초극소 저출생체중아에게 Ommaya reservoir를 삽입하여 2개월 이상 반복적인 뇌척수액 배액을 시행하였다. Ommaya reservoir는 출혈 후 수두증을 가진 초극소 저출생체중아에서 뇌실복강지름술이 가능한 시기까지 수두증 관리에 유용한 방법으로 생각된다. 같은 환아에서 치료 중 뇌척수액 배액에 동반된 저나트륨혈증이 발견되어 나트륨 투여로 치료하였던 1례를 보고한다. 되풀이되는 뇌척수액 배액이 필요한 영아에서 정기적 혈중 나트륨농도 측정이 필요할 것으로 생각된다.

• 대한소아치과학회지
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• 제34권1호
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• pp.13-18
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• 2007

맹출 중인 치아는 오랜 기간 동안 이동하는 과정에서 주위의 여러 요인들, 즉 유치의 조기 상실, 과잉치, 국소적 병소, 혀, 입술, 저작근, 외상 등에 의해서 다양한 영향을 받을 수 있다. 이러한 여러 요인들이 작용할 경우 치아의 정상적인 맹출 과정이 방해를 받게 되어 치아의 맹출 장애를 초래할 수 있다. 본 연구에서는 서울대학교 치과병원 소아치과에 2004년 1월 2일부터 2005년 12월 31일까지 신환으로 내원한 환자들, 총 8,010명의 주소를 분석하였고, 맹출 장애를 보이는 환자는 전체의 8.79%를 보였다. 맹출 장애의 유형은 맹출 지연이나 조기 맹출, 이소 맹출로 분류할 수 있었고, 맹출 지연이 가장 많이 나타난 치아는 상악 중절치이며, 조기 맹출이 호발한 치아는 하악 유중절치이고, 이소 맹출이 가장 많이 나타난 치아는 상악 제1대구치였다.

• 대한소아치과학회지
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• 제30권4호
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• pp.611-617
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• 2003

하악 견치의 매복은 약 0.1%의 발생 빈도로서 상악의 경우보다 드물게 나타나며, 매복의 원인으로는 맹출 및 배열 공간의 부족, 유견치의 조기상실, 과도한 치관 길이, 유전적 요인, 내분비선의 기능적 장애, 종양, 외상 등이 있다. 하악 매복 견치에 대한 치과적 접근으로는 교정적 힘을 가하여 매복치아를 구강으로 맹출시키는 방법과 외과적으로 매복치아를 노출시켜 제거하는 방법이 있다. 다음의 두 증례는 하악 매복 견치의 두 가지 치료 방법에 대한 것으로서 공간 부족, 매복 치아의 예후, 인접치아의 접근 정도 등을 고려하여 외과적 치료를 시행한 11세 여자 환자의 경우와 교정적 정출을 시도한 14세 남자 환자의 경우이며, 모두 양호한 결과를 얻었기에 보고하는 바이다.

• 농업과학연구
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• 제39권4호
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• pp.467-471
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• 2012

In this study, we investigated the antioxidative and antiaging activity of Perilla frutescens using LLC-$PK_1$ porcine renal epithelial cell and WI-38 human diploid fibroblast cell. The extract from Perilla frutescens showed strong protective effect against nitric oxide (NO) and superoxide ($O_2{^-}$)-induced oxidative stress generated by sodium nitroprusside (SNP) and pyrogallol, respectively. The result showed that P. frutescens increased the cell viability and showed scavenging activity of NO and $O_2{^-}$. In addition, the extract of P. frutescens exerted the protective effect against peroxynitrite ($ONOO^-$) induced by 3-morpholinosydnonimine. It suggests that P. frutescens would have the protective role against $ONOO^-$ itself and its precursors, NO and $O_2{^-}$. Furthermore, the aging model of hydrogen peroxide ($H_2O_2$)-treated WI-38 human diploid fibroblast was employed to investigate the anti-aging effect of P. frutescens. $H_2O_2$-treated WI-38 cells showed the loss of cell viability, however before-treatment with P. frutescens to WI-38 cells under premature senescence could delay the cellular aging process. The present study suggests the antioxidative and antiaging potential against free radical-induced oxidative damage of P. frutescens.