• 제목/요약/키워드: Predisposing factors

검색결과 286건 처리시간 0.023초

Development of De Novo Cavernous Hemangioma after Radiosurgery for Cavernous Hemangioma

  • Yeon, Je-Young;Suh, Yeon-Lim;Kim, Jong-Hyun;Lee, Jung-Il
    • Journal of Korean Neurosurgical Society
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    • 제48권6호
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    • pp.532-533
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    • 2010
  • We report a rare case of cavernous hemangioma (CH) which developed in adjacent location to a preexisting CH after gamma knife radiosurgery (GKRS). A 36-year-old woman underwent GKRS for a CH in the left lentiform nucleus. Three-and-half years after radiosurgery, MRI revealed a new CH in the left caudate nucleus. Surgical excision of the new lesion was performed. The pathological examination confirmed the diagnosis of CH. In radiosurgery for CH, it should be noted that a new CH may develop, which is likely to result from the interaction between radiation and predisposing factors of the patient.

Essential review points on the retrospective study of osteoradionecrosis in the jaws

  • Seo, Mi Hyun;Kim, Soung Min
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제46권3호
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    • pp.208-210
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    • 2020
  • Recently, after reviewing the online journal, Journal of the Korean Association of Oral and Maxillofacial Surgeons, we found a recently published original article by Manzano et al., entitled, "Retrospective study of osteoradionecrosis in the jaws of patients with head and neck cancer". Although this original article was well written and provided a great deal of information regarding osteoradionecrosis in the jaws, we would like to add a few additional recommendations based on our small concerns and recently updated articles.

Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism

  • Han, Ki Hoon
    • Korean Circulation Journal
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    • 제48권11호
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    • pp.951-963
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    • 2018
  • HMG-CoA reductase inhibitors, i.e. statins, are effective in reducing cardiovascular disease events but also in cardiac-related and overall mortality. Statins are in general well-tolerated, but currently the concerns are raised if statins may increase the risk of new-onset diabetes mellitus (NOD). In this review, the possible effects of statins on organs/tissues being involved in glucose metabolism, i.e. liver, pancreas, adipose tissue, and muscles, had been discussed. The net outcome seems to be inconsistent and often contradictory, which may be largely affected by in vitro experimental settings or/and in vivo animal conditions. The majority of studies point out statin-induced changes of regulations of isoprenoid metabolites and cellassociated cholesterol contents as predisposing factors related to the statin-induced NOD. On the other hand, it should be considered that dysfunctions of isoprenoid pathway and mitochondrial ATP production and the cholesterol homeostasis are already developed under (pre)diabetic and hypercholesterolemic conditions. In order to connect the basic findings with the clinical manifestation more clearly, further research efforts are needed.

노인의 사회복지서비스 이용실태와 이용에 영향을 미치는 요인 -경기도 국민기초생활보장노인을 중심으로- (Factors Influencing Utilization of the Social Services for the Elderly)

  • 박경숙
    • 한국사회복지학
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    • 제55권
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    • pp.283-307
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    • 2003
  • 우리나라 노인들의 사회복지서비스 이용은 매우 저조하고 서비스가 각기 독립적으로 제공되고 있기 때문에 중복과 누락현상이 나타나고 있음이 지적되어 왔다. 본 연구는 경기도 국민기초생활보장대상 노인들 전수를 대상으로 노인들이 어떠한 서비스기관으로부터 어떠한 사회복지서비스를 받고 있는지에 대해 살펴보고, 노인들의 사회복지서비스 이용기관수에 영향을 미치는 요인이 무엇인지 알아보고자 하였다. 연구결과 서비스중복 문제보다는 낮은 서비스이용률이 더 문제인 것으로 드러났다. 노인의 사회복지서비스 이용에 영향을 미치는 요인을 알아본 결과 비교적 욕구요인이 큰 비중을 차지하였고 그 외 귀속요인과 자원요인도 중에는 큰 영향을 미치는 변수들이 나타나, 사회복지서비스확충과 지역별 균형의 달성, 서비스 연계 활성화가 필요한 것으로 밝혀졌다.

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요보호자 부양가족의 성년후견제도 이용에 영향을 미치는 요인 (Influential Factors on Utilization of Adult Guardianship System in Dependent Family Caregivers)

  • 전병주;김건호
    • 한국콘텐츠학회논문지
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    • 제16권9호
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    • pp.482-490
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    • 2016
  • 한국에서 성년후견제도가 시행되고 3년이 경과하였다. 하지만, 다른 국가들과 비교해 제도 정착이 지연되고 있으므로 최적의 제도를 실현할 수 있는 실질적인 방안을 조속히 마련해야 한다. 이에 본 연구에서는 Anderson & Newman의 행동모델을 적용하여 장애인 및 치매노인 등 요보호자의 부양가족들을 대상으로 성년후견제도 이용에 영향을 미치는 요인을 분석하였다. 본 연구를 위해서 SPSS 18.0을 이용하였으며, 주요 연구결과는 다음과 같다. 첫째, 성년후견제도의 이용 의사는 보통수준으로 나타났다(M=3.08). 둘째, 성년후견제도 이용에 큰 영향을 미치는 요인은 욕구요인에서의 사회적 낙인, 가능요인에서의 경제상태, 선행 요인에서의 부양자와의 관계, 교육수준 등으로 나타났다. 이러한 실증적 분석결과를 토대로 성년후견제도가 필요한 요보호자와 그 가족들에게 제도 이용을 위한 구체적인 실천전략을 제시하였고, 나아가 성년후견제도의 조속한 정착과 올바른 운영을 위한 기초자료를 제공하였다는데 본 연구의 의의가 있다.

노년기 외래의료서비스 이용 궤적 및 예측요인 : 연령 차이를 중심으로 (The Trajectory of Outpatient Medical Service Use and Its Predictors: Focusing on Age Variations)

  • 강상경
    • 한국사회복지학
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    • 제62권3호
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    • pp.83-108
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    • 2010
  • 본 연구는 고령사회 준비를 위한 현황이해 차원에서 앤더슨 모형을 이용하여 노년기 외래의료 서비스 이용궤적 및 예측요인을 살펴보고, 초기노년기와 후기노년기 간에 궤적이나 예측요인이 차이가 있는지를 살펴보는 것을 목적으로 한다. 한국복지패널의 1, 2, 3차년도 자료를 사용하여, 궤적 및 예측 요인은 잠재성장모형을 이용해서 분석하였고 연령 차이는 다중집단분석을 이용하여 분석하였다. 60세 이상 노인들은 해가 지남에 따라서 외래이용 횟수를 증가시키는 경향을 보였는데, 75세 미만의 초기 노년기의 노인들이 75세 이상의 후기노년기의 노인들 보다가 이용 횟수를 상대적으로 빨리 증가시켰다. 예측요인에 있어서는 선행요인, 자원요인, 욕구요인들의 상당수가 궤적과 유의미한 관계가 있었는데, 자원요인 보다는 욕구요인들이 의료서비스 이용궤적에 크게 영향을 주는 것으로 나타났다. 하지만 예측요인에 있어서 초기 및 후기 노년기 사이에 큰 차이는 없었다. 결과를 토대로 연구의 의의 및 함의를 논의하였다.

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보건진료원의 보건의료서비스 공급에 관한 관련요인분석 (A Study on the Health Services Provision of Community Health Practitioners)

  • 김영임
    • 대한간호학회지
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    • 제18권2호
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    • pp.153-161
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    • 1988
  • The purpose of this study was to analyze the level of the services provision of community health practitioners (CHP) and to find out the influence factors on the services provision of CHP. In this study the dependent variables were the level of community health services(CHS), maternal and child health services(MCH), family planning services(FPS), primary care services(PCS) and the ratios of preventive health services(PHS). And independent variables were predisposing, community demographic and task factors. For this analysis, atepwise regression was used. Data collected for the study on reorganization of health centers organization in 1985 was partly used. The findings of this study can be summarized as follows : First, total variance of independent variables for CHS, MCH, FPS, PCS and PHS are shown 62.5 percent, 58.3 percent, 41.8 percent, 17 percent and 61.9 percent respectively. Second, the most important variables which explain CHS, MCH, FPS, PCS and PHS was ratios of household contacted ($R^2$=0.289), marital status ($R^2$=0.177), marital status($R^2$=0.167), ratios of household contacted($R^2$=0.119) and management of preventive health services($R^2$==0.203) respectively. The independent varivbles used in this analysis presented that the explnining for the provision of preventive health service are more influenced than primary care services. In summary this analysis suggests that the level of preventive health services provision of CHP is low and the provision of primary care services compared with preventive health services are occurred independentely. In the future, the strategies for active preventive services by CHP must to be strengthened.

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Type 1 diabetes genetic susceptibility markers and their functional implications

  • Park, Yongsoo
    • Journal of Genetic Medicine
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    • 제11권1호
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    • pp.1-10
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    • 2014
  • Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by selective destruction of pancreatic ${\beta}$-cells resulting in insulin deficiency. The genetic determinants of T1D susceptibility have been linked to several loci, in particular to the human leukocyte antigen (HLA) region, which accounts for 50% of the genetic risk of developing T1D. Multiple genes in the HLA region, which are in strong linkage disequilibrium, are thought to be involved. Another important locus, with a smaller effect on genetic predisposition to T1D, is the insulin gene. The advent of numerous single nucleotide polymorphism markers and genome screening has enabled the identification of dozens of new T1D susceptibility loci. Some of them appear to predispose to T1D independently of the HLA and may be important in families with T1D who lack strong HLA susceptibility. Other loci may interact with each other to cause susceptibility. The autoimmune response against ${\beta}$-cells can also be triggered by environmental factors in the presence of a predisposing genetic background. Deciphering the environmental and genetic factors involved should help to understand the origin of T1D and aid in the design of individualized prevention programs.

Primary angle-closure glaucoma, a rare but severe complication after blepharoplasty: Case report and review of the literature

  • Maria Kappen, Isabelle Francisca Petronella;Nguyen, Duy Thuan;Vos, Albert;van Tits, Hermanus Wilhelmus Hendricus Joseph
    • Archives of Plastic Surgery
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    • 제45권4호
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    • pp.384-387
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    • 2018
  • Blepharoplasty is one of the most commonly performed aesthetic procedures. Surgical complications are rare, but can have severe consequences, such as permanent vision loss. In this report, we describe a patient who developed primary angle-closure glaucoma (ACG) with associated vision loss after a oculoplastic procedure using local anesthesia. So far, six similar cases have been described in the literature. It is believed that acute ACG is triggered by the surgical procedure in patients with predisposing risk factors such as a cataract. Surgical triggering factors include the use of buffered lidocaine/xylocaine with adrenaline/epinephrine, stress, and coverage of the eyes postoperatively. Due to postoperative analgesic use, the clinical presentation can be mild and atypical, leading to a significant diagnostic delay. Acute ACG should therefore be excluded in each patient with postoperative complaints by assessing pupillary reactions. If a fixed mid-wide pupil is observed in an ophthalmologic examination, an immediate ophthalmology referral is warranted. Surgeons should be aware of this rare complication in order to offer treatment at an early stage and to minimize the chance of irreversible vision loss.

일부 농촌주민과 도시영세민의 상병 및 의료이용에 관한 연구 (Physician Utilization and its Determinants in Rural and Urban Slum Areas)

  • 이진희;고기호;김용식;이정애
    • Journal of Preventive Medicine and Public Health
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    • 제21권2호
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    • pp.404-418
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    • 1988
  • The household survey was performed in a urban slum and a rural Chonnam areas to measure the level of illness and medical care utilization and to find the determinants of physician utilization. The data revealed that age-adjusted prevalence rates of acute and chronic diseases were much the same in both areas ranged between 10.0 to 11.3%. But medical care utilization was more frequent in urban slum than in rural area. The facility of the first medical contact was also different. Some personal and disease related variables including disease severity and activity restricted day were significantly, but somewhat differently by area, associated with physician utilization pattern. When applying Anderson model, the medical need factors explained 42.2 and 40.4% of physician utilization in urban slum and in rural areas respectively, while the enabling factors explained 18.0 and 12.2% and the predisposing facotrs explained 17.1 and 8.9% correspondingly.

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