• Title/Summary/Keyword: Pre-treated

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Synthesis of New Uracil-5-Sulfonamide Derivatives and Immuno-Stimulatory Effect of a Chemically Modified Hemolymph of Biomphalaria alexandrina on Schistosoma mansoni Infected Mice

  • Fathalla, O.A.;Haiba, M.E.;Maghraby, A.S.
    • Archives of Pharmacal Research
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    • v.26 no.5
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    • pp.358-366
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    • 2003
  • Some N-p-substituted phenyl uracil-5-sulphonamide derivatives have been synthesized to be evaluated as molluscicides against Biomphalaria alexandrina snails, the intermediate host of Schistosoma mansoni. Schistosoma mansoni infected mice were treated with hemolymph obtained from pre-treated Biomphalaria alexandrina snails with the products 4a, 10a, 10b and 4b or obtained from non-treated snails. The selection of the concentration based on the predetermined dose which caused mortality of less than 50% of snails/24 h. $LC_{50}$ of compounds 4a, 10a, 10b and 4b was 50, 100, 200 and 50 ppm respectively. The result showed that immuno-stimulatory effect of treated hemolymph with compounds 4a, 10a and 4b was related to significant protective effects (44.4, 34.6 and 50.4% reduction in worm burden respectively). In addition, mean total worm burdens were significantly reduced in non treated hemolymph by 33.8%. The effect of hemolymph obtained from treated or non treated snails on S. mansoni adult worms antigens was studied by indirect immunofluorescence technique using chronic mouse sera (CMS). The results indicated that there was a strong reaction with epitopes in gut epithelium, tubercles, teigument and subtegumental musculature of untreated and treated S. mansoni adult worms antigens. Therefore, treatment of hemolymph obtained from pre-treated snails with compounds 4a, 10a, and 4b can stimulate specific immune response and induce protective effects against S. mansoni infection.

Effects of Acid Treatment of Carbon on Electroless Copper Plating (피도금 탄소재의 산처리가 무전해 동도금에 미치는 영향)

  • Shin, Ari;Han, Jun Hyun
    • Journal of the Korean institute of surface engineering
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    • v.49 no.3
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    • pp.265-273
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    • 2016
  • The effects of surface modification by nitric acid on the pre-treatment of electroless copper plating were investigated. Copper was electroless-plated on the nitric acid treated graphite activated by a two-step pre-treatment process (sensitization + activation). The chemical state and relative quantities of the various surface species were determined by X-ray photoelectron spectroscopy (XPS) after nitric acid modification or pre-treatment. The acid treatment increased the surface roughness of the graphite due to deep and fine pores and introduced the oxygen-containing functional groups (-COOH and O-C=O) on the surface of graphite. In the pre-treatment step, the high roughness and many functional groups on the nitric acid treated graphite promoted the adsorption of Sn and Pd ions, leading to the uniform adsorption of catalyst ($Pd^0$) for Cu deposition. In the early stage of electroless plating, a lot of tiny copper particles were formed on the whole surface of acid treated graphite and then homogeneous copper film with low variation in thickness was formed after 30 min.

Effects of Acrylamide Formation and Quality Characteristics Before Frying French Fries (튀김 전 후렌치후라이의 전처리가 아크릴아마이드 생성 및 품질특성에 미치는 영향)

  • Kim, Jin-Mam;Choi, Yun-Sang;Choi, Ji-Hun;Koo, Bon-Kou;La, Im-Joung;Kim, Cheon-Jei
    • Korean journal of food and cookery science
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    • v.28 no.4
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    • pp.407-412
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    • 2012
  • The objective of this research was to study the effect of pre-treatments before deep frying on the reduction in acrylamide formation, crispness and sensory properties of French fries. The acrylamide concentration was lower in pre-treated French fries before frying with citrus acid, ascorbic acid and salt solution than that in untreated French fries. Crispness, moisture and fat contents, color, texture and overall acceptability of pre-treated French fries were not significantly different compared to those in control. Therefore, French fries pre-treated with citrus acid, ascorbic acid and salt solution before frying had good sensory properties, and reduced acrylamide formation.

Dehydration and RDF Production of Organic Sludge with Hydrothermal Pre-treatment Process (증기열 전처리공정을 이용한 유기성 슬러지의 건조 및 성형연료화)

  • Park, Se-Joon;Choi, Yong-Sung;Lee, Kyung-Sup
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.58 no.4
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    • pp.526-531
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    • 2009
  • This paper suggests the dehydration and RDF(Refuse Derived Fuel) production of organic sludge, livestock manure and sewerage sludge causing environmental problems, with hydrothermal pre-treatment process. The renewable technology from the organic wastes must involve short treatment time required, reusable energy source, anti-odor and viruses, low cost for the treatment, and well-fertilization. The hydrothermal pre-treatment process promotes to evaporate moisture in the sludge after being shortly treated in a reactor, which is supplied steam and heat by an external boiler, due to the pressure with steam breaks the cell walls of the sludge, so this process removes the internal moisture of the cell. Then, the treated sludge(solid-state) is mixed with waste vinyls called RDF(6,706kcal/kg).

The Quality Characteristics of Deodeok-Doenjang Pre-treated by Various Sugaring Methods during Storage (전처리 당절임 방법 차이에 따른 더덕된장의 저장 중 품질특성)

  • Choi, Duck-Joo;Lee, Yun-Jung;Kim, Youn-Kyeong;Kim, Mun-Ho;Choi, So-Rye;Cha, Hwan-Soo;Youn, Aye-Ree
    • Korean journal of food and cookery science
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    • v.30 no.6
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    • pp.663-669
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    • 2014
  • We preprocessed and pickled Deodeok with Doenjang to improve its preservability and to distribute it widely, and we stored Deodeok for 3 weeks at $7^{\circ}C$ and measured its quality. The sample pre-treated with 20% of dextrin retained its early texture better than the samples pre-treated with other methods after 3 weeks of storage (p<0.05). The samples pre-treated with other controls showed propagation of microorganisms; but Doenjang pre-treated with 20% of dextrin or sugar showed less increase in the water content. The microorganisms count in samples pre-treated with other controls was 4.0 log CFU/g after 3 weeks of storage, but the microorganisms count in the sample pre-treated with 20% of dextrin was 2.2 log CFU/g; in other words, the propagation of microorganisms was minimized in the sample pre-treated with 20% of dextrin (p<0.05). In the investigation of the preferences, this D-20 sample showed maximum improvement in color, smell, taste, and other general preferences factors. Thus, the best processing method for the optimal quality maintenance of Deodeok is to sugarize it with 20% of dextrin before pickling with Doenjang. The product prepared using with this process can be preserved for 3 weeks at $37^{\circ}C$; that is, this product is expected to have a refrigerator shelf life of 3 months.

Observation of Growth Inhibition of Elsinoe fawcettii on Satsuma Mandarin Leaves Pre-treated with Rhizobacterial Strains by a Scanning Electron Microscope (식물근권세균을 처리한 감귤 잎에서 주사전자현미경을 통한 감귤 더뎅이병균의 생장 억제 관찰)

  • Park, Jae Sin;Song, Min-A;Jeun, Yong Chull
    • Research in Plant Disease
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    • v.22 no.1
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    • pp.1-8
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    • 2016
  • Elsinoe fawcettii causing citrus scab was suppressed by rhizobacterial strains such as Burkholderia gladioli MRL408-3, TRH423-3 and Pseudomonas fluorescens THJ609-3, TRH415-2 having antifungal activity. The leaf surface of Satsuma mandarin, which was pre-treated with the rhizobacterial strains, was observed by a scanning electron microscope (SEM) after inoculation with E. fawcettii. The number of lesions was reduced on the leaves pre-treated with the rhizobacterial strains compared to those of untreated leaves. Especially, the lesions numbers was apparently reduced on the leaves pre-treated with B. gladioli MRL408-3. The observation by SEM revealed that not only the germination rate but also the length of germ tube of the pathogen were decreased on the rhizobacterial strains pre-treated leaves. These inhibition of the fungal growth was more strongly expressed on the leaves pre-treated with commercial fungicide imibenconazole, by which the lesions was rarely found on the leaves. Based on these results, it was suggested that rhizobacterial strains may inhibit the germination and growth of the E. fawcettii on the surface of citrus leaves, resulting in decrease of disease severity.

A Trifloxystrobin Fungicide Induces Systemic Tolerance to Abiotic Stresses

  • Han, Song-Hee;Kang, Beom-Ryong;Lee, Jang-Hoon;Lee, Seung-Hwan;Kim, In-Seon;Kim, Chul-Hong;Kim, Young-Cheol
    • The Plant Pathology Journal
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    • v.28 no.1
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    • pp.101-106
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    • 2012
  • Trifloxystrobin is a strobilurin fungicide, which possesses broad spectrum control against fungal plant diseases. We demonstrated that pre-treating red pepper plants with trifloxystrobin resulted in increased plant growth and leaf chlorophyll content compared with those in control plants. Relative water content of the leaves and the survival rate of intact plants indicated that plants acquired systemic tolerance to drought stress following trifloxystrobin pre-treatment. The recovery rate by rehydration in the drought treated plant was better in those pre-treated with trifloxystrobin than that in water treated plants. Induced drought tolerance activity by trifloxystrobin was sustained for 25 days after initial application. The trifloxystrobin treated red pepper plants also had induced systemic tolerance to other abiotic stresses, such as frost, cold, and high temperature stresses. These findings suggest that applying the chemical fungicide trifloxystrobin induced systemic tolerance to certain abiotic stresses in red pepper plants.

Silver Loading Effect for the Activated Carbon Fibers Pre-treated with Acid

  • Oh, Won-Chun;Yum, Min-Hyung
    • Bulletin of the Korean Chemical Society
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    • v.25 no.8
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    • pp.1189-1194
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    • 2004
  • The adsorption isotherms of N2 onto the metallic silver treated activated carbon fiber samples after acid treatment are Type I with a small amount of capillary condensation hysteresis. Increasing amount of acid treatment leads to a decrease in SBETs and external surface area. But, micropore volume and average pore diameter are presented in constant regular values with increasing amount of sulfuric acid treatment. SEM observes the surface morphology and crystal grown state of metal on the fiber surface. The results of EDX of Ag-activated carbon fiber pre-treated with acid show the spectra corresponding to almost all samples rich in silver with increasing the amount of acid treated. The FT-IR spectra of Ag-activated carbon fiber show that the acid pre-treatment is consequently associated with the homogeneous dispersion of metal with the increased surface acidity of the activated carbon fiber. The type and quality of oxygen groups are determined with Boehm titration method. From the those results, a positive influence of the acidic groups on the carbon fiber surface by acid treatment is also demonstrated by an increase in the contents of metallic silver with increasing of acidic groups.

Influence of Rainfall During the Ripening Stage on Pre-Harvest Sprouting, Seed Quality, and Longevity of Rice (Oryza sativa L.)

  • Baek, Jung-Sun;Chung, Nam-Jin
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.59 no.4
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    • pp.406-412
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    • 2014
  • The influence of rainfall during the ripening stage on pre-harvest sprouting, seed viability, and seed quality was investigated in two Korean rice cultivars, Shindongjin and Hopum. When the rainfall was artificially treated in a greenhouse, HP started to pre-harvest sprouting at three days of rainfall treatment (DRT), but Shindongjin did not show pre-harvest sprouting at 40 DAH treatment and just 0.3~0.8% at 50 DAH, which was much lower than 15.3~25.8% of Hopum in the same treatment. After harvest, the seed germination of Hopum decreased about 10~25% compared to non-treated seeds, but that of Shindongjin decreased much little rate than that of Hopum. The seed longevity tested by accelerated aging decreased with prolonged rainfall period in both cultivars, but the varietal difference was clear; Shindongjin could withstand longer accelerated aging than Hopum. Shindongjin maintained its germination (>50%) ability after 15 days of accelerated aging regardless of the rainfall treatment period and time, but Hopum dropped below 50% germination ability after only 5 days of accelerated aging. In conclusion, rainfall during the ripening stage induced not only pre-harvest sprouting, but also reduced seed quality and longevity during storage, which varied between two cultivars.

Pre- and In-Hospital Delay in Treatment and in-Hospital Mortality after Acute Myocardial Infarction

  • An, Kyuneh;Koh, Bongyeun
    • Journal of Korean Academy of Nursing
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    • v.33 no.8
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    • pp.1153-1160
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    • 2003
  • Purpose. 1) To identify the time taken from symptom onset to the arrival at the hospital (pre-hospital delay time) and time taken from the arrival at the hospital to the initiation of the major treatment (in-hospital delay time) 2) to examine whether rapid treatment results in lower mortality. 3) to examine whether the pre- and in-hospital delay time can independently predict in-hospital mortality. Methods. A retrospective study with 586 consecutive AMI patients was conducted. Results. Pre-hospital delay time was 5.25 (SD=10.36), and in-hospital delay time was 1.10 (SD=1.00) hours for the thrombolytic therapy and 50.24 (SD=121.18) hours for the percutaneous transluminal coronary angio-plasty (PTCA). In-hospital mortality was the highest when the patients were treated between 4 to 48 hours after symptom onset using PTCA (p=.02), and when treated between 30 minutes and one hour after hospital arrival using thrombolytics (p=.01). Using a hierarchical logistic regression model, the pre- and in-hospital delay times did not predict the in-hospital mortality. Conclusion. Pre- and in-hospital delay times need to be decreased to meet the desirable therapeutic time window. Thrombolytics should be given within 30 minutes after arrival at the hospital, and PTCA should be initiated within 4 hours after symptom onset to minimize in-hospital mortality of AMI patients.