• Title/Summary/Keyword: Pre-control Line

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Antibody Induced by the JY-Pol Pneumococcal Conjugate Protects Mice Against systemic Infection Due to Streptococcus pneumoniae (JY-Pol 접합백신으로 유도된 항페렴구균 항체의 보호효과)

  • Lee, Jue-Hee;Han, Yong-Moon
    • YAKHAK HOEJI
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    • v.48 no.6
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    • pp.369-373
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    • 2004
  • We previously reported that Streptococcus pneumoniae capsule attached to the surface protein (JY-Pol) was protective to systemic pneumococcal infection. The JY -Pol antigen induced IgM, IgG, and IgA in mice and provoked cell-mediated immunity. In this current study, we investigated the effect of anti JY-Pol antiserun and monoclonal antibody C2 (Mab C2) specific for the JY-Pol antigen against the pneumococcal disease. Mice that were given the antiserum survived longer than mice that received antiserum pre-absorbed with S.pneumoniae cells or DPBS as a negative control. Heat-treated anti JY-Pol antiserum resulted in survival rates similar to intact fresh JY-Pol antiserum. Mab C2 isolated from JY-Pol-immunized mice also enhanced resistance of naive mice against the pneumococcal diseaser. This protection by Mab C2 appeared to be mediated by opsonization as determined in a RAW 264.7 monocyte/macrophage cell line. Epitope analysis showed that Mab C2 epitope consisted of glucuronic acid and glucose that blocked the interaction of JY-Pol to the C2. Taken together, these data indicate that the antiserum induced by the JY-Pol, a naturally pneumococcal conjugate formula, mediated the protection by passive transfer, which was confirmed by protective effect of Mab C2.

DC-DC Boost Converter using Offset-Controlled Zero Current Sensor for Low Loss Thermoelectric Energy Harvesting Circuit (저 손실 열전변환 하베스팅을 위해 제로전류센서의 오프셋을 조절하는 부스트 컨버터)

  • Joo, Sunghwan;Kim, Kiryong;Jung, Dong-Hoon;Jung, Seong-Ook
    • Journal of IKEEE
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    • v.20 no.4
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    • pp.373-377
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    • 2016
  • This paper presents a low power boost converter using offset controlled Zero Current Sensor (ZCS) control for thermoelectric energy harvesting.[1] [5] Offset controlled ZCS uses adjustable pre-offset that is controled by 6bit code each connected gate of NMOS for switching. Offset controlled ZCS demonstrates an efficiency that is higher than using analog comparator ZCS and that is smaller area than using delay line ZCS. Experimentally, the offset controlled ZCS system consumes 10 times less power than analog comparator ZCS based system at similar performance.

A Study on the Mark Reader Using the Image Processing (영상처리를 이용한 Mark 판독 기법에 관한 연구)

  • 김승호;김범진;이용구;노도환
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.83-83
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    • 2000
  • Recently, Vision system has being used all around industry. Sensor systems are used for Mark Reader, for example, optical scanning is proximity sensor system, have many disadvantages, such as, lacking user interface and difficulty to store original specimens. In contrast with this, Vision systems for Mark Reader has many advantages, including function conversion to achieve other work, high accuracy, high speed, etc. In this thesis, we have researched the development of Mark Reader by using a Vision system. The processing course of this s)'stem is consist to Image Pre-Processing such as noise reduction, edge detection, threshold processing. And then, we have carried out camera calibration to calibrate images which are acquired from camera. After searching for reference point within scanning area(60pixe1${\times}$30pixe1), we have calculated points crossing by using line equations. And then, we decide to each ROI(region of interest) which are expressed by four points. Next we have converted absolute coordinate into relative coordinate for analysis a translation component. Finally we carry out Mark Reading with images classified by six patterns. As a result of experiment which follows the algorithm has proposed, we have get error within 0.5% from total image.

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Performance Characteristics of a Main Oxidizer Shutoff Valve for Liquid Rocket Engines (액체로켓엔진용 연소기 산화제 개폐밸브 성능 특성)

  • Jeong, Daeseong;Hong, Moongeun;Han, Sangyeop
    • Journal of the Korean Society of Propulsion Engineers
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    • v.21 no.4
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    • pp.28-35
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    • 2017
  • A main oxidizer shutoff valve controls the supply of the oxidizer flow into the combustion chamber of a liquid rocket engine. This shutoff valve also carries out the pre-chilling of oxidizer supply lines by permitting recycling flow for stable transient start of the engine. In the present paper, the flow tests for the recycling line of the valve were conducted in order to evaluate the cooling performance of the main oxidizer shutoff valve. In addition, cryogenic life-cycle tests were performed with an assumption of the increase of spring constant with increasing valve operating times due to ductile-brittle transition effects.

Development of Non-Invasive Pressure Estimation Using 3D Multi-Path Line Integration Method from Magnetic Resonance Velocimetry (MRV) (자기공명유속계 (MRV) 에서 3차원 다중경로 선적분법을 활용한 비침습적 압력예측 방법 개발)

  • Ilhoon Jang;Muhammad Hafidz Ariffudin;Simon Song
    • Journal of the Korean Society of Visualization
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    • v.21 no.2
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    • pp.14-23
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    • 2023
  • The pressure difference across stenotic blood vessels is a commonly used clinical metric for diagnosing many cardiovascular diseases. At present, most clinical pressure measurements rely solely on invasive catheterization. In this study, we propose a novel method for non-invasive pressure estimation using the incompressible Navier-Stokes equations and a 3D multi-path integration approach. We verify spatio-temporal convergence on an in-silico dataset of a cylindrical straight pipe phantom with steady and pulsatile flow fields. We then evaluate the proposed method on an in vitro dataset of reconstructed control, pre-operative, and post-operative carotid artery cases acquired from 4D flow MRI. The performance of our method is compared to existing approaches based on the pressure Poisson equation and work-energy relative pressure. The results demonstrate the proposed method's high accuracy, robustness to spatio-temporal subsampling, and reduced sensitivity to noise, highlighting its great potential for non-invasive pressure estimation.

3D Character Motion Synthesis and Control Method for Navigating Virtual Environment Using Depth Sensor (깊이맵 센서를 이용한 3D캐릭터 가상공간 내비게이션 동작 합성 및 제어 방법)

  • Sung, Man-Kyu
    • Journal of Korea Multimedia Society
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    • v.15 no.6
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    • pp.827-836
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    • 2012
  • After successful advent of Microsoft's Kinect, many interactive contents that control user's 3D avatar motions in realtime have been created. However, due to the Kinect's intrinsic IR projection problem, users are restricted to face the sensor directly forward and to perform all motions in a standing-still position. These constraints are main reasons that make it almost impossible for the 3D character to navigate the virtual environment, which is one of the most required functionalities in games. This paper proposes a new method that makes 3D character navigate the virtual environment with highly realistic motions. First, in order to find out the user's intention of navigating the virtual environment, the method recognizes walking-in-place motion. Second, the algorithm applies the motion splicing technique which segments the upper and the lower motions of character automatically and then switches the lower motion with pre-processed motion capture data naturally. Since the proposed algorithm can synthesize realistic lower-body walking motion while using motion capture data as well as capturing upper body motion on-line puppetry manner, it allows the 3D character to navigate the virtual environment realistically.

Implementation of Image-based Virtual Fence for Surveillance Area Setup (감시영역 설정을 위한 영상 기반 가상펜스 구현)

  • Kim, Jae-jun;Kim, Do-yeon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.9
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    • pp.2145-2152
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    • 2015
  • The existing CCTV has limitation such as problem on usage of the off-line type of recorded image for specific investigation, and requirement on interactive operator intervention for real-time surveillance. Therefore, it is required to develop the intelligent CCTV equipped with various functionalities in order to overcome drawbacks mentioned above. In this paper, implementation methods of image-based virtual fence were proposed by using the spline curves with supplied control for setup of surveillance area. In addition, pre-alarm region within the predefined distance was established with tangent and normal lines extracted from control points. The image-based virtual fence can be used for remote detection of intrusion and provision of real-time intrusion alarm, and can be expected to use in safety-related application areas including security and crime prevention.

Effects of Dietary Approaches to Stop Hypertension Program on Blood Pressure among the Pre-hypertension Group in the Community (지역사회 주민의 고혈압 예방 식이프로그램의 효과 평가)

  • Jo, Heui-Sug;Shim, Jeong-Ha;Jeong, Heon-Jae;Hwang, Moon-Sun;Lee, Hye-Jean;Kim, Myung-Hee
    • Journal of agricultural medicine and community health
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    • v.31 no.3
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    • pp.237-244
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    • 2006
  • Objectives: DASH (dietary approaches to stop hypertension) diet are recommended as first-line therapy for prevention of hypertension individuals with high normal blood pressure. We studied the effects of DASH program on blood pressure among the pre-hypertension group. Methods: To determine the impact of dietary patterns on the control of hypertension we studied the subgroup of 141 participants with systolic blood pressure of 120 to 139 mm Hg or diastolic BP of 80 to 89mmHg, body mass index(BMI) ${\geq}25kg/m^3$ or waist to hip ratio(WHR) ${\geq}0.95$(for man). 0.85(for woman) enrolled in DASH program. Participants were received of education and consulting about DASH every week for 8 weeks. Results: The level of diet to prevention of hypertension and compliance of DASH increased after education. Also, The DASH program significantly reduced systolic BP (from $136.03{\pm}12.40mmHg$ to $126.09{\pm}11.25mmHg$, p< .01) and diastolic BP (from $81.80{\pm}6.32mmHg$ to $76.44{\pm}10.61mmHg$, p< .01). Conclusion: The DASH program effectively lowers BP and may be useful in achieving prevention of hypertension.

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Effects of Self Directed Learning Applying Basic Nursing Practice Contents of e-Learning on Nursing Students' Knowledge, Self Confidence and Satisfaction (e-Learning기본간호실습 콘텐츠를 이용한 자기주도학습이 간호학생의 지식, 자신감, 교육만족도에 미치는 효과)

  • Jo, Hyun-Sook;Park, Eun-Young;Choi, Jeong-Sil
    • The Journal of the Korea Contents Association
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    • v.13 no.9
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    • pp.504-514
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    • 2013
  • Purpose: This study was to identify the educational effects of self directed learning applying basic nursing practice contents of e-learning on nursing students' knowledge, self-confidence, and learning satisfaction. Method: This study applied a quasi-experimental pre-test and post-test control group design with 63 freshman nursing students (31 experimental group, 32 control group) of G. university in Incheon, Korea as subjects. The e-learning content was about the application of topical medications, central line care, and blood transfusion. All were available at the web site in school. Self-directed e-learning was more than 120 min.(3 times a week, 2 weeks)during Sep-Nov in 2011. In both groups, there were no significant difference in general characteristics, self-directed learning readiness, knowledge, and self-confidence for the pre-homogeneity. Results: The experimental group showed a higher level of improvement in knowledge and learning satisfaction but not significantly. However, the self-confidence was significantly improved in the experimental group. Conclusion: When self-directed learning using e-learning contents added to the conventional practical class, it may be beneficial for the nursing students to learn skills effectively.

Time Course Variation of Vitamin $C_3$ Content in Leg Skin of Broiler Chicks Exposed to Different Dose of UVB Light (자외선의 상이한 선양을 조사한 브로일러 병아리의 다리 피부중 비타민 $C_3$ 함양의 경시적 변화)

  • 장윤환;김강수;여영수;강훈석;조인호;배은경
    • Korean Journal of Poultry Science
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    • v.20 no.2
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    • pp.93-105
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    • 1993
  • This study was carried out to determine the concentrations of previtamin D$_3$(PreD$_3$), lumisterol$_3$(L3), tachystero1$_3$(73), vitamin D$_3$(VD$_3$) and provitamin D$_3$(ProD$_3$) in leg skins of broiler chicks exposed to UVB lights (maximum intensity at 297 nm) with dose of 0.204 or 0.409 mJ/$\textrm{cm}^2$(30 or 60 min irradiation) . The broiler Hubbard line day old chicks(2 dose $\times$9 elapsed time $\times$4 replica+10 control=82) were fed VD-deficient diet for 31 days in a windowless subdued light room. The skin was collected at 0, 6, 12, 18, 30, 42, 66, 90 or 138 hr after UVB irradiation. The skin lipid was extracted by 9% ethyl acetate/n-hexane, and the fraction of VD$_3$ and its analogues was purified by Sep-Pak silica cartridge. The straight phase HPLC was utilized to analyze ProD$_3$ and its products. The mole %(absolute level expressed in ng/$\textrm{cm}^2$) of PreD$_3$ in leg skin (epidermis+dermis) was 4.67%(44 ng/$\textrm{cm}^2$) or 3.97%(37 ng/$\textrm{cm}^2$) right after UVB irradiation by 0.204 or 0.409 mJ/$\textrm{cm}^2$(30 or 60 min) at 15 cm distance, respectively. It content in leg skin at 0 hr after exposure was 7.24%(12 ng/$\textrm{cm}^2$) or 0.92%(9 ng/$\textrm{cm}^2$), respectively. The increase in irradiation dose did not affect proportionally the If synthesis.73 concentration in leg skin was 0.58%(S ng/$\textrm{cm}^2$) or 0.57%(6 ng/$\textrm{cm}^2$), respectively 0 hr after irradiation. The VD$_3$ in leg skin of birds exposed to UVB light with dose of 0.204 or 0.409 mJ/$\textrm{cm}^2$ was 2.13% (21 ng/$\textrm{cm}^2$) or 0.97% (16ng/$\textrm{cm}^2$), respectively at 0 hr after exposure, 2.72%(26ng/$\textrm{cm}^2$) or 3.84%(37ng/$\textrm{cm}^2$), respectively at 6 hr, and 4.30% ((33ng/$\textrm{cm}^2$) or 6.40%(76ng/$\textrm{cm}^2$), respectively at 12 hr. The peak concentration of VD$_3$ was presented at 18 or 30 hr when 0.204 or 0.409 mJ/$\textrm{cm}^2$) was treated, respectively. It was shown that 18~30 hr were necessary for the thermal conversion of PreD$_3$ into VD$_3$ in the leg skin of broiler chicks. The ProD$_3$ contents in leg skins of negative control, 0.204 mJ/$\textrm{cm}^2$ and 0.409 mJ/$\textrm{cm}^2$ treated birds were 966, 948 and 815 ng/$\textrm{cm}^2$, respectively at right before and after UVB exposure. It was estimated that 18 or 151 ng/$\textrm{cm}^2$ of ProD$_3$ was isomerized to PreD$_3$, L$_3$, T$_3$ and VD$_3$ when exposed to 0.204 or 0.409 mJ/$\textrm{cm}^2$, respective)y. Consequently it was shown that when double dose of UVB light was applied to irradiate the chick body, more but not double synthesis of VD$_3$ and its analogues was occured in leg skin of brolier chicks.

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