• Structural Engineering and Mechanics
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• v.68 no.4
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• pp.409-421
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• 2018

In the present paper, functionally graded (FG) materials are presented to investigate the bending analysis of simply supported plates. It is assumed that the material properties of the plate vary through their length according to the power-law form. The displacement field of the present model is selected based on quasi-3D hyperbolic shear deformation theory. By splitting the deflection into bending, shear and stretching parts, the number of unknowns and equations of motion of the present formulation is reduced and hence makes them simple to use. Governing equations are derived from the principle of virtual displacements. Numerical results for deflections and stresses of powerly graded plates under simply supported boundary conditions are presented. The accuracy of the present formulation is demonstrated by comparing the computed results with those available in the literature. As conclusion, this theory is as accurate as other shear deformation theories and so it becomes more attractive due to smaller number of unknowns. Some numerical results are provided to examine the effects of the material gradation, shear deformation on the static behavior of FG plates with variation of material stiffness through their length.

• Journal of Applied Reliability
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• v.18 no.3
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• pp.193-200
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• 2018

Purpose: In this study, the life of the motor is investigated by performing the accelerated life test with the brush wear of the industrial cleaner motor as the main failure mode. Methods: The accelerating stress factor of the accelerated life test is a voltage, which can increase the number of revolutions of the motor to accelerate the brush wear due to the friction between the brush and the commutator. Also, the accelerating stress level was determined after determining the maximum allowable level of the voltage through the preliminary test. Results: The motor failure time at each accelerating stress level was predicted by regression analysis with brush wear length as performance degradation data. The main failure mode, which is brush wear, of the motor was reproduced by this test. The shape parameter of the Weibull distribution was confirmed to be the same statistically at all accelerating stress levels by the likelihood ratio test. Conclusion: The life of the motor was investigated by performing the accelerated life test with the brush wear of the industrial cleaner motor as the main failure mode. Through the accelerating test method of the cleaner motor, various life expectancy and life expectancy of the acceleration factor are predicted.

• Geomechanics and Engineering
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• v.12 no.1
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• pp.9-34
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• 2017

In this work, an efficient and simple quasi-3D hyperbolic shear deformation theory is developed for bending and vibration analyses of functionally graded (FG) plates resting on two-parameter elastic foundation. The significant feature of this theory is that, in addition to including the thickness stretching effect, it deals with only 5 unknowns as the first order shear deformation theory (FSDT). The foundation is described by the Pasternak (two-parameter) model. The material properties of the plate are assumed to vary continuously in the thickness direction by a simple power law distribution in terms of the volume fractions of the constituents. Equations of motion for thick FG plates are obtained within the Hamilton's principle. Analytical solutions for the bending and free vibration analysis are obtained for simply supported plates. The numerical results are given in detail and compared with the existing works such as 3-dimensional solutions and those predicted by other plate theories. It can be concluded that the present theory is not only accurate but also simple in predicting the bending and free vibration responses of functionally graded plates resting on elastic foundation.

• Computers and Concrete
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• v.25 no.1
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• pp.37-57
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• 2020

This work investigates a new type of quasi-3D hyperbolic shear deformation theory is proposed in this study to discuss the statics and free vibration of functionally graded porous plates resting on elastic foundations. Material properties of porous FG plate are defined by rule of the mixture with an additional term of porosity in the through-thickness direction. By including indeterminate integral variables, the number of unknowns and governing equations of the present theory is reduced, and therefore, it is easy to use. The present approach to plate theory takes into account both transverse shear and normal deformations and satisfies the boundary conditions of zero tensile stress on the plate surfaces. The equations of motion are derived from the Hamilton principle. Analytical solutions are obtained for a simply supported plate. Contrary to any other theory, the number of unknown functions involved in the displacement field is only five, as compared to six or more in the case of other shear and normal deformation theories. A comparison with the corresponding results is made to verify the accuracy and efficiency of the present theory. The influences of the porosity parameter, power-law index, aspect ratio, thickness ratio and the foundation parameters on bending and vibration of porous FG plate.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.38 no.4
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• pp.315-320
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• 2010

To improve not only the basic performance but also the fail-safe performance, power consumption of the main landing gear for helicopters, a semi-active control landing gear using hybrid MR damper, was introduced in this paper. This damper of the configuration to install a permanent magnet in a electromagnet MR damper, was designed by the trade-off study on permanent magnet location and a magnet field analysis. Force control algorithm which keep the sum of air spring force and damping force at a specified value during landing, was used for the controller. The drop simulations using ADAMS Model for this semi-active control landing gear, were done. The improvement of the preceding performances as the result to evaluate the landing performance by the simulations, has been confirmed.

• Applied Chemistry for Engineering
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• v.5 no.6
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• pp.1062-1067
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• 1994

The chemistry of 5-methyl-4-imidazolecarboxylic acid ester synthesis involves three distinct reaction steps. Of these the rate of formation of diketone was found to be a function of oxime and HCl concentration and temperature by the batch experiment. The decomposition of diketone was found to be a slow process whereas temperature was the only variable to affect it significantly. An empirical rate expression for the net formation of diketone fits the experminetal data satisfactorily. The principal objectives of this study are to study the kinetics of the diketone formation reaction and to develop the empirical rate expression.

• Molecules and Cells
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• v.37 no.12
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• pp.888-898
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• 2014

Pancreatic cancer is one of the most fatal cancers and is associated with limited diagnostic and therapeutic modalities. Currently, gemcitabine is the only effective drug and represents the preferred first-line treatment for chemotherapy. However, a high level of intrinsic or acquired resistance of pancreatic cancer to gemcitabine can contribute to the failure of gemcitabine treatment. To investigate the underlying molecular mechanisms for gemcitabine resistance in pancreatic cancer, we performed label-free quantification of protein expression in intrinsic gemcitabine-resistant and -sensitive human pancreatic adenocarcinoma cell lines using our improved proteomic strategy, combined with filter-aided sample preparation, single-shot liquid chromatography-mass spectrometry, enhanced spectral counting, and a statistical method based on a power law global error model. We identified 1931 proteins and quantified 787 differentially expressed proteins in the BxPC3, PANC-1, and HPDE cell lines. Bioinformatics analysis identified 15 epithelial to mesenchymal transition (EMT) markers and 13 EMT-related proteins that were closely associated with drug resistance were differentially expressed. Interestingly, 8 of these proteins were involved in glutathione and cysteine/methionine metabolism. These results suggest that proteins related to the EMT and glutathione metabolism play important roles in the development of intrinsic gemcitabine resistance by pancreatic cancer cell lines.

• Korean Journal of Food Science and Technology
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• v.24 no.6
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• pp.619-622
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• 1992

To increase utilization of Korean yam, the rheological properties of gelatinized yam (Dioscorea aimadoimo) starch solutions at various concentrations $(1{\sim}5%)$ and temperature $(30{\sim}60^{\circ}C)$ were investigated. The rheological behavior of gelatinized yam starch solutions was illustrated by power-law model and Casson equation and exhibited pseudoplastic behavior with yield stress. The pseudoplasticity of starch solutions increased largly concentration of starch increased. As the temperature increased from $30^{\circ}C$ to $60^{\circ}C$, the dependency of starch concentration decreased, B were decreased from 0.40449 to 0.39352. The activation energy of flow of gelatinized yam starch solutions were increased from 4.1415 to $5.45329{\times}10^6\;J/kg{\cdot}mol$ by increasing starch concentration from 1% to 5%.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.53 no.5
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• pp.681-687
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• 2020

Physicochemical properties of fucoidan and alginate extracted from Sargassium horneri were investigated. The alginates were extracted and purified via three different routes (CaCl₂, HCl and ethanol routes), and their rheological properties at various concentrations and temperatures were determined. The yield of fucoidan was 3.08%, and it was mainly composed of fucose and galactose. Fourier-transform infrared spectrum of fucoidan showed strong absorption band at 1,254 and 827 cm^-1 corresponding to the sulfate group. Flow behavior of the alginate solution was characterized using the power-law model. The consistency index increased with increasing concentrations. The sodium alginate solution (1.5%) exhibited Newtonian behavior when extracted via the CaCl₂ and HCl routes, while it exhibited pseudoplastic behavior when extracted via the ethanol route. The effect of temperature on the flow behavior was investigated in terms of the activation energy (E_a), which was obtained using the Arrhenius equation. The E_a value corresponding to the alginate solution decreased with increasing shear rates. The E_a values corresponding to the alginate solutions purified via the CaCl₂, HCl, and ethanol routes were 13.54-18.64 kJ/mol, 13.42-19.21 kJ/mol, and 9.51-10.67 kJ/mol, respectively. The low E_a values corresponding to the solutions extracted via the ethanol route suggest that the flow behavior does not depend significantly on temperature.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.12
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• pp.1325-1333
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• 2011

An analytical, numerical, and experimental comparison of the hydraulic and thermal performance of new vascular channels with semicircular cross sections was conducted. The following conditions were employed in the study: Reynolds number, 30-2000; cooling channels with a volume fraction of the cooling channels, 0.04; and pressure drop, $30-10^5$ Pa. Three flow configurations were considered: first, second, and third constructal structures with diameters optimized for hydraulic operations. To validate the proposed vascular designs by an analytical approach, 3-D numerical analysis was performed. The numerical model was also validated by the experimental data, and the comparison results were in excellent agreement in all cases. The validation study against the experimental data showed that compared to traditional channels, the optimized structure of the cooling plates could significantly enhance heat transfer and decrease pumping power.