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Anti-aging Effects of Prescription Extracts Containing Forsythia viridissima L. (연교를 함유한 처방단 추출물의 항노화 효과)

  • Kim, Mi Jin;Jung, Taek Kyu;Yoon, Kyung-Sup
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.1
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    • pp.85-96
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    • 2015
  • Forsythia fructus has been shown to have antioxidative, anti-inflammatory, antibacterial, anti-aging and whitening effects. This work was carried out to investigate the anti-aging effects of Forsythia viridissima-prescription extracts (Yeongyoseungma-tang, Gamiyeongyoseungma-tang, Hoechunyangkyeok-san) on skin. Skin anti-aging effect of Forsythia viridissima-prescription extracts (Yeongyoseungma-tang, Gamiyeongyoseungma-tang, Hoechunyangkyeok-san) was evaluated by using antioxidant assay, anti-glycation activity, inhibitory effect of tyrosinase activity, expression of type I procollagen and UVA-induced matrix metalloproteinase-1 on HS68 cells, and reduction of ${\alpha}$-MSH-induced melanin on B16F1 cells. Forsythia viridissima-prescription extracts showed anti-oxidative and anti-glycation activity. The pectinex hydrolysed extract from Yeongyoseungma-tang 75% EtOH extract and Gamiyeongyoseungma-tang 75% EtOH extract increased the type I procollagen synthesis, and decreased the UVA-induced MMP-1 expression on HS68 cells. The pectinex hydrolysed extracts of Hoechunyangkyeok-san 75% EtOH extract had the inhibitory effect of melanin synthesis on B16F1 cells. Based on these results, we suggest that Forsythia viridissima-prescription extracts may be useful as a potential source of functional anti-aging cosmetics.

A Study on the Azolla imbricata using as a Cosmetic Active Ingredient (물개구리밥(Azolla imbricata)을 이용한 주요 활성성분의 분리 및 화장품 소재 개발 연구)

  • Song, Min-Hyeon;Bae, Jun-Tae;Lee, Geun-Su;Zhang, Yong-He;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.36 no.1
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    • pp.71-77
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    • 2010
  • The water fern Azolla belongs to the Azollaceae and forms a symbiotic association with a $N_2$-fixing cyanobacterium, referred to as Anabaena azollae, and this association has currently been demonstrated to have potential as a nitrogen source for rice production. Because of that, Azolla fern has been used not only as organic manure in southern China and northern Vietnam for a long time but also as food for animate creatures in the underwater and decontaminant in the water. However, the phenolic compounds and active materials of Azolla have not been examined in detail in the past studies. In the present study, anti-oxidant ability test and experiment to find a particular active material of Azolla imbricata and Azolla imbricata fraction (AIF) were performed. In anti-oxidant test such as DPPH test and lipoxygenase inhibition test, the value of test represented high activities compared with authentic sample - green tea and NDGA (nordihydroguaiaretic acid). In MMP-1 test, related to collagen protection and elasticity of skin, its inhibitory effect was measured over 75 %, and the phenolic compounds of AIF related with this activity were confirmed luteolin derivatives by using FT-IR spectroscopy, element analyzer (EA) and Liquid chromatography-MASS spectroscopy.

Analysis of General Components and Vitamin and Mineral Contents of the Mushroom Agrocybe chaxingu (차신고버섯(Agrocybe chaxingu)의 일반성분, 비타민 및 미네랄 함량분석)

  • Lee, Kwang-Jae;Yun, In-Jue;Kim, Hee-Yeon;Park, Yu-Hwa;Ham, Hun-Ju;Park, Young-Hak;Joo, Jin-Ho;Lim, Sang-Hyun;Kim, Kyung-Hee
    • Food Science and Preservation
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    • v.16 no.4
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    • pp.549-553
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    • 2009
  • The mushroom Agrocybe chaxingu was analyzed to evaluate the nutritional value of this potential food. The moisture content was 88.9% in the fruiting body of A. chaxingu, and the proportions of ash, crude fiber, carbohydrate, crude protein, and crude fat were 0.9%, 1.4%, 7.2%, 2.5% and 0.4% by weight, respectively. A. chaxingu contained 1.29 mg/100 g edible weight of vitamin $B_1$, and the contents of vitamin $B_2$, vitamin $B_3$, and vitamin C were 0.15 mg, 0.32 mg, and 18.4 mg per 100 g of wet mushroom. Potassium (3,318 mg/100 g, dry basis) was found at the highest concentration in A. chaxingu. In addition, the mushroom contained many other minerals (all figures are mg per 100 g of dried mushroom) such as phosphorus (909.7), magnesium (141.3), sodium (12.7), zinc (7.4), iron (6.5), copper (2.8), manganese (0.8), and nickel (0.1). The results indicate that A. chaxingu is a valuable nutrient source.

Components and Biological Effects of Fermented Extract from Tartary Buckwheat Sprouts (타타리메밀싹 발효추출물의 영양성분 및 생리활성)

  • Chang, Kwang-Jin;Seo, Geon-Sik;Kim, Yang-Sik;Huang, Dae-Sun;Park, Jong-In;Park, Jeong-Ja;Lim, Yong-Sup;Park, Byoung-Jae;Park, Cheol-Ho;Lee, Man-Hee
    • Korean Journal of Plant Resources
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    • v.23 no.2
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    • pp.131-137
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    • 2010
  • Tartary buckwheat has potential as a source of functional food because it contains a number of bioactive compounds such as rutin, catechin and so on. This study was conducted to determine the possibility of development of processed products extracted from sugar-treated sprouts of tartary buckwheat. By using undiluted solution extracted from sprouts of tartary buckwheat, we analyzed their nutrition components and did in vivo experiment to find out pharmaceutical effects. In an experiment using mice, we administered various concentration of buckwheat to induced diabetic mellitus mice for 1 weeks. As a result, the fermented extract from buckwheat sprouts effected finely on lowering blood sugar and decreased LDL-cholesterol and total lipid level but increased HDL-cholesterol level.

Study on the Lowering of NaCl Content by Co-composting Food Wastes (저농도 식염을 함유하는 음식물쓰레기 퇴비제조)

  • Lee, In-Bog;Park, Chang-Kyu;Kim, Pil-Joo
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.1
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    • pp.17-25
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    • 2001
  • High salt content in food waste limit use as the potential source of compost. Since sodium chloride content should be lower than one percent to meet requirement for agricultural use of compost, we attempted use of three kinds of co-composting material for food wastes compost, which were fermented, dried, and fresh types of amendments which included pig manure, sawdust and puffed rice hull. Food wastes were composted well and stabilized after around the 40th days of composting. Little difference were found between composts amended sawdust and puffed rice hull. The result indicated that puffed rice hull could be used as a good alternative of sawdust. Because sawdust or puffed rice hull were mixed as amendments to control water contents and to dilute high NaCl content of compost material, the C/N ratios of the final products were significantly high over 40. However, NaCl contents of final products were dropped to less than percent on the fresh weight basis by mixing food wastes and the above amendments with the optimum rates.

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Lipids from the rhizome of Cnidium officinalis Makino (천궁으로부터 lipid 의 분리 동정)

  • Kim, Hyoung-Geun;Jeon, Hyeong-Ju;Nguyen, Trong Nguyen;Lee, Dae Young;Baek, Nam-In
    • Journal of Applied Biological Chemistry
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    • v.64 no.4
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    • pp.343-349
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    • 2021
  • The rhizomes of Cnidium officinalis were extracted in aqueous MeOH, and the concentrate was fractionated via systematic solvent fractionation to EtOAc, n-BuOH, and aqueous fractions. The repeated column chromatography of EtOAc and n-BuOH fractions using silica gel, octadecyl silica gel, and Sephadex LH-20 as stationary phase to afford five lipids. They were identified to be methyl linoleate (1), linoleic aicd (2) 6-linoleoyl-𝛼-D-glucopyranosyl 𝛽-D-fructofuranoside (3), 1-linolenoyl-3-(𝛼-D-galactopyranosyl (1→6)-𝛽-D-galactopyranosyl) glycerol (4), and 1-linoleoyl-3-(𝛼-D-galactopyranosyl (1→6)-𝛽-D-galactopyranosyl) glycerol (5) on the basis of spectroscopic data such as IR, MS, and Nuclear magnetic resonance (NMR). Compounds 1 and 3-5 were isolated for the first time from this plant in this study. The NMR data of fatty acids 1 and 2 reported in literatures are different each other. Authors identified the NMR data without ambiguity. Compound 3, a conjugate of sucrose and fatty acid, and compounds 4 and 5, digalactosyl monoglyceride, are very rarely occurred in natural source. Through the immune enhancement and anticancer activity of the reported lipid compounds, the potential as various pharmacologically active materials of Cnidium officinalis rhizome can be expected.

Biogenic Synthesis of Metallic Nanoparticles and Their Antibacterial Applications (금속 나노입자의 생체 합성과 항균적 적용)

  • Patil, Maheshkumar Prakash;Kim, Jong-Oh;Seo, Yong Bae;Kang, Min-jae;Kim, Gun-Do
    • Journal of Life Science
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    • v.31 no.9
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    • pp.862-872
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    • 2021
  • Recent studies on synthesis of metallic nanomaterials such as silver (Ag), gold (Au), platinum (Pt), cerium (Ce), zinc (Zn), and copper (Cu) nanoparticles (NPs) using plants and microbes are attracted researchers for their wide range of applications in the field of biomedical sciences. The plant contains abundant of bioactive contents such as flavonoids, alkaloids, saponins, steroids tannins and nutritionals components. Similarly, microbes produce bioactive metabolites, proteins and secretes valuable chemicals such as color pigments, antibiotics, and acids. Recently reported, biogenic synthesis of NPs in non-hazardous way and are promising candidates for biomedical applications such as antibacterial, antifungal, anti-cell proliferative and anti-plasmodia activity. All those activities are dose dependent, along with their shape and size also matters on potential of NPs. Microbes and plants are great source of metabolites, those useful in biomedical field, such metabolites or chemicals involved in synthesis of NPs in an ecofriendly way. NPs synthesized using microbes or plant materials are reveals more non-toxic, facile, and cost-effective compare to chemically synthesized NPs. In present review we are focusing on NPs synthesis using biological agents such as microbes (bacteria, fungi and algae) and plant, characterization using different techniques and their antibacterial applications on pathogenic Gram-positive and Gram-negative organisms.

A Study on Anti-oxidant and Anti-wrinkle Effect of Supercritical Fluid Extraction of Black Carrot as a Functional Cosmetic Material (기능성화장품소재로서 자색당근 초임계추출물의 항산화 및 항주름 효능 연구)

  • Kim, Ji-Su;Lee, Ji-An
    • Journal of Convergence for Information Technology
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    • v.11 no.12
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    • pp.236-243
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    • 2021
  • The aim of this study was to evaluate the anti-oxidant and anti-wrinkle effect of the black carrot(BC) extracted by supercritical dioxide(SC-CO2). DPPH/ABTS radical scavenging and total polyphenol contents were measured to investigate the anti-oxidant activity of the BC supercritical extract. Collagen production and MMP-1 expression were assessed in normal human dermal fibroblasts(NHDF) for anti-wrinkle activity, The black carrot extract showed the highest total phenolic content(9.037±1.123 mg GAE/g extract) and the best antioxidant properties as shown by DPPH and ABTS assay. The supercritical fluid extracts of black carrot exhibited low toxicity to NHDF cells. In addition, the supercritical fluid extracts showed MMP-1 inhibition and type I pro-collagen synthesis inducing activities in a dose-dependent manner, respectively. Therefore, these results suggest that the black carrot is a potential source of high anti-oxidative, solvent-free and anti-aging material with promising applications in cosmetic, food, and beauty-food industries.

Comparative Study of Korean Workers' Exposure to Dichloromethane by Process Category between Work Environment Monitoring Program and ECETOC TRA (국내 디클로로메탄 제조·사용 사업장 근로자의 공정별 노출수준에 대한 작업환경측정값과 ECETOC TRA 모델값 비교연구)

  • Jeong, Sujin;Bae, Gyewan;Lee, Naroo
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.4
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    • pp.317-330
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    • 2021
  • Objectives: By law, companies in Korea must periodically measure workers' exposure to harmful chemicals (the system is called the Work Environment Monitoring Program (WMP)[a]) and report the results to the government. The government also measures exposure to monitor the WMP's reliability (called Reliability Assessment (RA) for WMP[b]). The issue is that measured data from these two sources are so different that the objectivity of WMP needs to be confirmed by comparing the results using the European Centre for Ecotoxicology and Toxicology of Chemicals' Targeted Risk Assessment (ECETOC TRA). Methods: Step 1: Data collection from WMP reports submitted by companies (n=586) and RA for WMP written by the government (n=33). Step 2: Data Standardization by key information included. Step 3: Data conversion to input-variables required to run the ECETOC TRA model, and run the model with specific data (n=514) which meet the predetermined exposure scenario. Step 4: Statistical data analysis by process category (PROC) and ventilation type from each source ([A] and [B]). Step 5: Additional analysis of any unexpected results. Results: The process categories of the production and handling of Dichloromethane were classified into 12 PROCs, and ten of them were selected to run ECETOC TRA. Modeled values tended to be higher than measured values from both sources. For the measured values from WMP, RCR distribution by PROC was narrow (0.197-0.267, 95% CI) and did not have a relationship with ventilation type, which differs from the tendency of the modeling result. Meanwhile, the measured values from RA for WMP were relatively widely distributed (0.301-1.177, 95% CI) by PROC. In particular PROCs (13,19) were high enough to exceed 1. Also, they become low with better ventilation types and appear differently depending on the ventilation type, similar to the model result. Conclusions: This study revealed that ECETOC TRA might have the potential to serve as a screening tool for exposure assessment and to be used as assistive method for WMP to estimate exposure. Further empirical study is required to confirm its availability as a screening tool.

Faith beyond Religion: A Study on the Faith-based films after 2010s in Hollywood (종교를 넘어선 신념: '영성'을 주제로 한 2010년대 할리우드 영화 고찰)

  • Ahn, SooJeong
    • Cross-Cultural Studies
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    • v.47
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    • pp.163-190
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    • 2017
  • This paper studies the recent surge in the number of faith-based films in Hollywood, with the aim to explore the context and implications of this new trend. By using the theoretical framework of the study of the Tilich and Van der Leeuw, who have explored the relationship between religion, culture and art, this article discusses the meaning of the spiritual theme in the film. A couple of common points can be found among the faith-based films that have been produced since the 2010s. While these films attempt a universal approach to the fundamental theme of spirituality through popular narratives familiar to the audience, they also stress 'historical truthfulness and credibility' by representing the reality, such as a featuring real person or a true story in the film. The main characters are depicted as "victorious losers" that are distinguished from the typical Hollywood superhero and the films repeatedly show the human being constantly 'asking' questions to God. By analyzing these characteristics, the paper demonstrates that recent Hollywood faith-based films have successfully differentiated themselves from existing religious films while symbolizing the universal beliefs and values beyond the religious message so as to attract more audiences to this field. The paper also suggests that despite the advances in modern science and knowledge, the public will always yearn for a spiritual recovery and salvation through the film medium, serving as a potential source that provides an outlet for spiritual experience.