• Journal of Korean Academy of Nursing
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• v.41 no.2
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• pp.191-196
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• 2011

Purpose: We investigated the effects of group III mechanoreceptors to cardiovascular responses in both pre-menopausal woman and post-menopausal woman during passive ankle dorsiflexion (PAD). Methods: Twenty healthy volunteers (10 post-menopausal women and 10 pre-menopausal women) were recruited for this study. Stroke volume (SV), heart rate (HR), cardiac output (CO), and total vascular conductances (TVC) were measured continuously throughout the experiment. To stimulate the group III mechanoreceptors, PAD was performed for one minute. Results: The results showed that mean arterial pressure (MAP) mediated by the mechanoreflex activation was significantly increased in both groups. However, this pressor response was significantly higher in post-menopausal women. This reflex significantly increased both SV and CO in pre-menopausal women, while there were no differences in post-menopausal women. There was no difference in HR in either group. The mechanoreflex significantly decreased TVC in post-menopausal woman, while there was no difference in pre-menopausal woman. Conclusion: The results indicate that the excessive pressor response mediated by the mechanoreflex occurs due to overactivity of group III mechanorecptors and the mechanism is produced mainly via peripheral vasoconstriction in post-menopausal women.

• Women's Health Nursing
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• v.26 no.4
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• pp.336-345
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• 2020

Purpose: This study aimed to identify factors influencing quality of life in post-menopausal women. Methods: The participants were 194 post-menopausal women who visited a women's clinic in Changwon, Korea from July 1 to August 31, 2018, and completed questionnaires containing items on menopausal symptoms, marital intimacy, current menopausal hormone therapy (MHT), and quality of life. Collected data were analyzed by descriptive statistics, the independent t-test, Pearson correlation coefficients, and multiple regression using SPSS for Windows version 23.0. Results: Quality of life had a significant negative correlation with menopausal symptoms (r=-.40, p<.001), and a significant positive correlation with marital intimacy (r=.54, p<.001). The factors influencing the quality of life of post-menopausal women were current MHT (t=6.32, p<.001), marital intimacy (t=4.94, p<.001), monthly family income (t=4.78, p<.001), menopausal symptoms (t=-4.37, p<.001), and education level (t=3.66, p<.001). These variables had an explanatory power of 59.2% for quality of life in post-menopausal women. Conclusion: In order to improve the quality of life of post-menopausal women, nursing interventions are needed to help menopausal women choose appropriate MHT, alleviate menopausal symptoms, and increase marital intimacy. Interventions should also be prioritized for women of a low educational level and with a low income in consideration of their health problems.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6639-6641
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• 2014

Background: To evaluate the clinical significance of atypical squamous cells of undetermined significance (ASCUS) in PAP test in post-menopausal women and compare with reproductive age women. Materials and Methods: A total of 367 patients who referred to our gynecologic oncology clinic were included to the study between September 2012 and August 2013. Data for 164 post-menopausal (group 1) and 203 pre-menopausal (group 2) women with ASCUS cytology were evaluated retrospectively. Immediate colposcopy and endocervical curettage was performed for both groups and conization for all women with a result suggestive of CIN2-3. Histopathological results and demographic features of patients were compared between the two groups. Results: Mean age of the patients was $54.6{\pm}6.5$ years in group 1 and $38{\pm}6.6$ years in group 2. Some 14 (8.5%) of post-menopausal women and 36 (17.7%) of pre-menopausal women were current smokers (p=011). Totals of 38 (23.2%) post-menopausal and 64 (31.5%) pre-menopausal women were assessed for HPV-DNA. High risk HPV was detected in 7 (4.3%) and 21 (10.3%), respectively (p=0.029). Final histopathological results recorded were normal cervix, low grade cervical intra-epithelial neoplasia (CIN 1), and high grade cervical intra-epithelial neoplasia (CIN2-3). In group 1 results were 84.8%, 12.2% and 1.8%, respectively, and in group 2 were 71.9%, 23.2% and 4.9%. There were no cases of micro invasive or invasive cervical carcinoma in either group. Two cases were detected as endometrial carcinoma in the menopausal group (1.2%). Conclusions: In current study we found that preinvasive lesions were statistically significantly higher in pre-menopausal women than post-menopausal women with ASCUS. Cervicitis was more common in menopausal women. Therefore, we think that in case of ASCUS in a post-menopausal woman there is no need for radical management.

• Journal of Korean Medicine for Obesity Research
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• v.20 no.1
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• pp.20-30
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• 2020

Objectives: The purpose of this study is to verify the effects of H Gambitang (GB-001) on body composition and basal metabolic rate in pre- and post-menopausal obese woman retrospectively. Methods: The study was conducted on 57 middle-aged obese women. They were divided into two groups; pre-menopausal obesity group (Pr-MOG; n=34) and post-menopausal obesity group (Po-MOG; amenorrhea was continued to 14~48 month, n=23) with no significant difference of age, height, body weight and body mass index. All subjects took herbal medicine 3 times a day, for 6 weeks during treatment period. The weight, height, body fat mass, skeletal muscle mass, and basal metabolic rate of all subjects were measured on first visit. The following measurements were repeated after 2 weeks (2nd), 4 weeks (3rd) and 6 weeks (4th) with Inbody 370 (Biospace) equipment to identify changes of body fat mass, skeletal muscle mass, and basal metabolic rate. Results are represented as mean and standard deviation. Results: Po-MOG showed significantly lower decrease rate in weight reduction on 2~6 weeks while significantly higher decrease rate in skeletal muscle reduction on 4~6 weeks. There were no significant differences between two groups in body fat reduction rate and basal metabolic increasing rate. Conclusions: H Gambitang (GB-001) can be used not only in Pr-MOG but in Po-MOG in weight loss although the effect can be lower in Po-MOG. To prevent skeletal muscle mass loss in Po-MOG, following study on adjusting dose and components of H Gambitang (GB-001) thought to be necessary.

• Journal of radiological science and technology
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• v.34 no.3
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• pp.195-201
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• 2011

We studied the relationship between prediction parameters and bone mineral density for pre-and-post menopausal women. We measured BMI%Fat by BIA, blood pressure and lipid profiles for 483 adult women who are in NPO state. SBP, TC, TG, LDL have significant statistical value in the postmenopause women group and postmenopause woman. The value of postmenopause women of these parameters are lower than premenopause woman. BMD has the most strongest relationship with LBM. The BMD and LDL level of postmenopause women have statistically negative relationship. The results show that for the premenopause cases, weight, BF, and HDL level were the major factors which affect the BMD. For postmenopause cases, however, weight, age, and LDL level turned out to be the most significant factors.

• Journal of Naturopathy
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• v.9 no.2
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• pp.57-61
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• 2020

Purpose: Purpose: This study was to study the effect of foot bathing on menopausal symptoms and sleep disorders in female subjects in their 50s with menopausal symptoms. Methods: After 12 weeks of foot bath therapy three times a week, pre- and post-menopausal signs were measured. Results: Subjects with hot flashes, heart discomfort, sleep problems, depression, irritability, anxiety, physical and mental fatigue, sexual problems, urination problems, vaginal dryness, and joint and muscle discomfort significantly improved after than before(p < .001). Subjective sleep quality, sleep incubation period, sleep duration, sleep disturbance score, sleep drug use, and sleep dysfunction significantly decreased after foot bath than before(p < .001). Habitual sleep efficiency increased considerably. Conclusions: The subjects showed overall improvement in menopausal symptoms and sleeping quality after a foot-bath. Therefore, foot bath therapy is evaluated as a natural healing therapy suitable for improving menopausal symptoms and sleep.

• Health Policy and Management
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• v.17 no.4
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• pp.113-133
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• 2007

The present study was conducted to measure health-related utility for post-menopausal symptoms among Korean woman. A survey questionnaire was developed to measure utility based on visual analogue scale(VAS) and time trade-off method (TTO). From January 29 to February 3, 2007, a face-to-face interview was conducted with 274 women aged 45 to 60 to ask about their subjective utility for hypothetical health status of mild or severe post-menopausal symptoms. Among the participants, 160 were recruited from outpatient departments of 3 hospitals and 114 from 2 sports centers located in Seoul. For mild symptom, the average utility score of the respondents was $0.63{\pm}0.14$ based on VAS and $0.61{\pm}0.26$ based on ITO. For severe symptoms, the average utility was $0.39{\pm}0.16$(VAS) and $0.44{\pm}0.27$ (TTO). For severe symptom, a higher utility score was observed for TTO than for VAS, which is consistent with earlier studies and thus supports the validity of the utility measurement in this study. Overall, the severity of post-menopausal symptoms of the respondents themselves was not significantly associated with the utility score that the respondents answered for hypothetical health status. Multiple regression analysis results showed that the utility score was significantly higher among respondents with older age, higher education, higher family income, and from hospitals. It is expected that the utility score measured in this study will enhance the understanding of the quality of life of women after menopause and will be used to conduct cost-utility analysis of health care interventions to treat post-menopausal symptoms.

• The Journal of Korean Medicine
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• v.39 no.2
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• pp.106-118
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• 2018

Objectives: This study was performed to investigate anti-obesity effects of Zingiberis Rhizoma on ovariectomized rats in order to determine the possibility of the clinical use in preventing and treating post-menopausal obesity. Methods: To investigate how menopause affects obesity in woman, rats were treated with Zingiberis Rhizoma extracts. We measured various biomarkers including GOT,GPT, leptin, ghrelin, adiponectin, $PPAR-{\gamma}$ mRNA, total cholesterol, triglyceride, HDL-cholesterol, liver weight, estradiol, uterine weight, and calcitonin, which are linked with obesity and menopause. Results: There was a significant decrease in group which was given Zingiberis Rhizoma extracts 100 mg/kg and lipid level found in blood(total cholesterol, triglyceride). Fat accumulation of liver cells was repressed, liver function was improved and leptin and adipomectin levels were significantly normalized. In addition, expression of $PPAR-{\gamma}$ was significantly increased. Conclusions: The results indicated that Zingiberis Rhizoma extracts have anti-obesity effects on ovariectomized rats through improving liver function and lipid metabolic function.

• Women's Health Nursing
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• v.5 no.2
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• pp.204-221
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• 1999

Due to the ever increasing life-span of human beings, the average woman is living well into her 70's. Henceforth, they spend at least one-third of their life after menopause. Climacteric encompasses the time preceding, during, and proceeding menopause : a transitional period of shifting from the period of being fertile to the period of senescence. In other words, this is the time at which they lose the ability to reproduce. Menopause can influence a woman's sexual life immensely due to the physiological, social, and psychological changes that occur during that period. In korea, where some women still live according to Confucian Culture in terms of sexology, nurses can play a vital role in the dissemination of sexual facts to women. This study was designed to clarity the characteristic and satisfaction of sexual life. This was done according to the classification of three types of climacteric women : pre-meno-pausal, menopausal, and post-menopausal. I studied 159 climacteric women between the ages of 45 & 59, living in or around the vicinity of Taegu City. This study utilized the investigative tools for sexual life patterns which were constructed with field experts' consultation and reference review by the author. The sexual satisfaction was translated from DSFI. The climacteric symptoms were invented by Kupperman, This research is descriptive. The data was collected between July 15, 1998 and October 14, 1998. Statistical analysis was performed using ANOVA and Pearson Correlations, and was computed with the SPSS program. The results obtained are summarized as follows; The frequency of sexual activity was highest in pre-menopause and declined after menopause. The frequency of genital caressing declined after menopause. The difference between the frequency of masturbation and coital pain was not significant according to the classification set forth in this experiment. Congruently, the frequency of orgasms declined after menopause. The mean satisfaction of sexual life is 27.1 years. The range of expected score is 9-45 years of age. Satisfaction was highest in the pre-menopausal group and proved to be statistically significant. Some of the general characteristics that affected the satisfaction a woman's sexual life in the climacteric stage during this project were ; age, income, satisfaction in younger pre-menopausal and the large income group than the other experimental groups. The climacteric symptoms were conversely correlated with the satisfaction in one's sexual life.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.7
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• pp.1112-1121
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• 2014

The purpose of this study was to investigate intake status and recognition of health functional foods by pre- and post-menopausal women in Seoul and Gyeonggi province. Survey questions were administered to 400 women around menopausal period, and data analysis was completed using the SPSS window program. Thirty-three percent of women recognized that they are healthy, and 47.1% of respondents are concerned with maintaining their health. However, respondents showed a low level of knowledge about the definition of menopause and health functional foods. Health concerns of respondents were significantly affected by marital status and level of education (P<0.05). Purchasing and intake of health functional foods was also significantly affected by health concerns and menopause symptoms (P<0.05). Twenty-nine percent of participants had taken health functional foods to prevent disease. However, most of them (85.9%) showed no knowledge of the main components of functional foods. In addition, knowledge associated with menopause and functional foods was affected by the level of education. The respondents' health concern, and thus purchase and intake frequencies of health functional foods, were affected by level of education. 'Effect of functional foods' was a top priority when respondents purchased health functional foods. The respondents answered black bean and pomegranate as foods that relieve menopause symptoms. However, they actually showed high intake frequency of black beans than pomegranate due to the high accessibility of black beans. The results of this study show that educational support for dietary guidelines is needed for middle-aged woman to be healthy after menopause.