• Clinical Endoscopy
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• 제56권4호
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• pp.409-422
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• 2023

Endoscopic resection (ER) is widely utilized as a minimally invasive treatment for upper gastrointestinal tumors; however, complications could occur during and after the procedure. Post-ER mucosal defect leads to delayed perforation and bleeding; therefore, endoscopic closure methods (endoscopic hand-suturing, the endoloop and endoclip closure method, and over-the-scope clip method) and tissue shielding methods (polyglycolic acid sheets and fibrin glue) are developed to prevent these complications. During duodenal ER, complete closure of the mucosal defect significantly reduces delayed bleeding and should be performed. An extensive mucosal defect that comprises three-quarters of the circumference in the esophagus, gastric antrum, or cardia is a significant risk factor for post-ER stricture. Steroid therapy is considered the first-line option for the prevention of esophageal stricture, but its efficacy for gastric stricture remains unclear. Methods for the prevention and management of ER-related complications in the esophagus, stomach, and duodenum differ according to the organ; therefore, endoscopists should be familiar with ways of preventing and managing organ-specific complications.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2005년도 추계 학술대회 발표논문집
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• pp.189-192
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• 2005

This study investigates the asymmetry effect between acoustics and perception. The examined cues are closure duration, closure voicing, VOT, release, pre-vowel duration, post-vowel duration. Five native speakers of English and 30 Korean college students participated in the present study. The results showed that high level Korean English learners parallels native speakers in their responses, while mid and low level Korean learners are substantially different from natives.

• Journal of Chest Surgery
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• 제29권9호
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• pp.1045-1049
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• 1996

기관내 상관후 발병하는 기관식도루는 희귀하고 치료하기 어려운 질환이다. 본원에서는 3명의 환자에서 4차례의 수술적 치료를 경험하였다. 인공 호흡기로부터 이탈 후 경부를 통해 접근하여 누공을 분리 후 기관 결손은 단순 봉합하고 식도 결손은 2층으로 봉합한 후 근육 피판을 두 봉합선 사이에 위치시킴으로써 재발을 방지하였다. 각각 1례의 지연성 기관협착과 재발성 기관식도루가 발생하였으나 이 또한 성공적으로 치료되었다.

• Nuclear Engineering and Technology
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• 제34권4호
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• pp.406-414
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• 2002

In TSPA of long-term post closure radiological safety on permanent disposal of HLW in Korea, appropriate management of input and output data through QA is necessary. The robust QA system is developed using the T2R3 principles applicable for five major steps in R&D＇s. The proposed system is implemented in the web-based system so that all participants in TSPA are able to access the system. In addition, the internet based input database for TSPA is developed. Currently data from literature surveys, domestic laboratory and field experiments as well as expert elicitation are applied for TSPA.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2018년도 춘계학술논문요약집
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• pp.23-24
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• 2018

• 음성과학
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• 제13권2호
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• pp.133-145
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• 2006

In order to understand the various groups' perceptual pattern in both VCV trochee and iambus, this study examined the identification correctness and cue robustness for the unit intervals in light of background language, age, and English listening ability. The 4 groups of Native Speakers of English, Korean College Students of High Listening Achievement, Korean College Students of Low Listening Achievement, and Korean Elementary Students took part in the experiments. Tokens of $/d{\ae}per,\;d{\ae}per,\;d{\ae}per,\;d{\ae}per,\;d{\ae}per,\;d{\ae}per$ in trochee and of $/{\eth}{\partial}\;p{\ae}d,\;{\eth}{\partial}\;b{\ae}d,\;{\eth}{\partial}\;t{\ae}d,\;{\eth}{\partial}\;d{\ae}d,\;{\eth}{\partial}\;k{\ae}d,\;{\eth}{\partial}\;g{\ae}d/$ in iambus were extracted and modified into experimental signals composed of two digits(voiced-1, voiceless-0) by following the temporal intervals, in which the signals consisted of preceding vowel, closure, VOT, and post-vowel. In the first experiment of identification correctness in VCV iambus environment, all groups showed almost 100% correctness rate, while in trochee environment all groups were different(native speaker 87%, college high 74%, college low 70%, elementary 65%). In the second experiment of cue robustness, all groups showed the similar perceptual pattern in both environments. There was the order of robustness cues in VCV trochee: pre-vowel ${\gg}$ closure ${\gg}$ VOT ${\gg}$ post-vowel, while the order in VCV iambus: VOT ${\gg}$ post-vowel ${\gg}$ closure ${\gg}$ pre-vowel. In some condition, however, we found moderately different perceptual pattern depending on language, age and listening level.

• The Journal of Korean Physical Therapy
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• 제22권3호
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• pp.87-92
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• 2010

Purpose: The purpose of this study was to investigate the effect of electrical stimulation (ES) on the wound closure rate, collagen deposition, and TGF-${\beta}$1 mRNA expression in skin wound of rat. Methods: Twenty male Sprague-Dawley rats (222~271 g) were randomly divided into ES (n=10) and control group (n=10). The ES group received a cathodal stimulation with 50 V at 100 pps for 30 minutes for 7 days, while the control group was not given electrical stimulation. The wound closure rate, collagen density and TGF-${\beta}$1 mRNA ratio were measured. Results: The mean wound closure rates in the ES and control groups were $83.79{\pm}16.35$% and $51.57{\pm}17.76$%, respectively (p<0.001). The collagen density in the ES and control groups were $46.67{\pm}10.68$% and $25.03{\pm}13.09$%, respectively (p<0.001). The TGF-${\beta}$1 mRNA ratio in the ES and control groups were $1.35{\pm}0.60$ and $0.63{\pm}0.30$, respectively at 6 hours post-wound (p<0.01) and $1.69{\pm}0.47$ and $1.32{\pm}0.28$, respectively, at 7 days post-wound (p<0.05). Conclusions: ES accelerated the wound closure rate of skin incision wounds and was accompanied by an increase in collagen deposition in the regenerating dermis. In addition, ES increased TGF-${\beta}$1 mRNA expression during wound healing process. These findings suggest that ES may activate TGF-${\beta}$1 expression, and may increase synthesis activities of fibroblasts in regenerating skin wounds in rats.

• 방사성폐기물학회지
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• 제11권4호
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• pp.311-324
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• 2013

우리나라 중저준위 방사성폐기물 최종 처분시설인 월성원자력환경관리센터의 폐쇄 후 안전평가 컴퓨터 프로그램의 신뢰성 확보를 위해 MASCOT와 검증프로그램으로 SAFE-ROCK와 GOLDSIM을 선정하여 정상시나리오에 대하여 안전평가를 수행하였다. 각 프로그램의 장단점을 비교/분석하였으며, 각 프로그램 별 구획 간의 선량 및 누출량을 평가하였다. 그 중 방사성핵종 $^{129}I$와 $^3H$가 MASCOT와 SAFE-ROCK 프로그램에서는 비슷한 경향을 보여주었지만, GOLDSIM 프로그램에서는 상이한 결과를 나타냈다. 이는 각 프로그램의 근계지역 내 핵종이동방정식의 해석과정의 차이와 개별 프로그램의 한계로 인해 다른 결과값을 보여주는 것으로 분석되었다. GOLDSIM 프로그램의 경우, 선원항 구획에서 초기 핵종누출량은 time-scale에 민감하게 반응한다는 사실도 확인할 수 있었다. 안전평가 프로그램은 처분환경에서 발생하는 핵종거동 및 이동에 대한 실제현상을 예측하기 위해 모델링을 거치지만, 전산프로그램의 특성과 실제현상에 대한 데이터가 제한적이므로 결과에 차이가 발생하게 된다. 이러한 차이점은 다양한 프로그램을 이용한 결과와 상호비교를 통해 알아내며 그 원인을 지속적으로 분석하는 연구개발과정을 필요로 하고 있다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권2호
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• pp.147-162
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• 2022

Purpose: To design a prospective study on endovascular closure of congenital portosystemic shunts. The primary endpoint was to assess the safety of endovascular closure. The secondary endpoint was to evaluate the clinical, analytical and imaging outcomes of treatment. Methods: Fifteen patients (age range: 2 days to 21 years; 10 male) were referred to our center due to congenital portosystemic shunts. The following data were collected prior to treatment: age, sex, medical history, clinical and analytical data, urine trimethylaminuria, abdominal-US, and body-CT. The following data were collected at the time of intervention: anatomical and hemodynamic characteristics of the shunts, device used, and closure success. The following data were collected at various post-intervention time points: during hospital stay (to confirm shunt closure and detect complications) and at one year after (for clinical, analytical, and imaging purposes). Results: The treatment was successful in 12 participants, migration of the device was observed in two, while acute splanchnic thrombosis was observed in one. Off-label devices were used in attempting to close the side-to-side shunts, and success was achieved using Amplatzer™ Ductus-Occluder and Amplatzer™ Muscular-Vascular-Septal-Defect-Occluder. The main changes were: increased prothrombin activity (p=0.043); decreased AST, ALT, GGT, and bilirubin (p=0.007, p=0.056, p=0.036, p=0.013); thrombocytopenia resolution (p=0.131); expansion of portal veins (p=0.005); normalization of Doppler portal flow (100%); regression of liver nodules (p=0.001); ammonia normalization (p=0.003); and disappearance of trimethylaminuria (p=0.285). Conclusion: Endovascular closure is effective. Our results support the indication of endovascular closure for side-to-side shunts and for cases of congenital absence of portal vein.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2002년도 추계학술발표회요약집
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• pp.326.1-326
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• 2002