• 한국건설관리학회논문집
• /
• 제19권2호
• /
• pp.15-24
• /
• 2018

국내 건설산업에서 생산성 정보의 필요성과 그 활용에 대한 중요성 인식에도 불구하고, 현장 단위의 공사계획 시 효과적인 피드백을 통한 생산성 정보관리가 미흡한 실정이다. 공사계획의 신뢰성을 향상하기 위해서는 생산성 정보의 효과적인 활용이 요구되지만, 현장에서는 공사계획을 관리자의 경험 및 직관에 의존하고 있다. 생산성 정보가 효과적으로 관리되지 못하는 이유는 생산성 정보의 관리를 위한 추가 인력투입이 어렵다는 점, 기존의 생산성 정보가 새로운 프로젝트에 적용되기 어렵다는 점 등 때문인 것으로 파악되었다. 이러한 문제의 해결방안을 제시하기 위해서 선행연구조사 및 면담조사를 하였고 그 결과 새로운 시스템이 필요하다는 사실을 확인하였다. 새로운 시스템의 요구사항으로는 최소화된 업무, 한정된 정보관리범위, 정보의 분류, 정보의 피드백, 생산성 저하요인의 고려 등이 있다. 본 연구에서는 상기 내용을 바탕으로 생산성 저하요인 및 생산성 정보의 관리가 가능한 시스템의 프레임워크를 제안하였다. 이 시스템은 사용자 접근성이 좋은 SketchUp 소프트웨어를 활용하여 프로그램의 활용에 따른 추가인력의 투입이나 업무량 증가를 최소화할 수 있도록 하였다. 제안한 시스템은 준비단계, 입력단계, 처리단계, 출력단계의 총 네 단계의 과정을 통해서 정보를 입력하여 처리하고 출력하도록 하였다. 입력한 시공정보는 건축공사 표준시방서에 기재된 내용을 참고로 구성한 Task Breakdown Structure (TBS)와 Material Breakdown Structure (MBS)를 통해서 분류되어 생산성 정보로 변환되도록 하고, 변환된 정보를 그래픽으로 화면에 출력하도록 하여 사용자는 이를 활용해 해당 현장에서의 생산성 정보를 활용할 수 있도록 하였다. 본 연구에서 제안한 생산성 정보관리 시스템을 K 사옥 공사현장에 대입하여 현장적용 가능성 및 정보 활용성 측면에서 검증하였고, 사용성 및 적용 가능성에서 매우 긍정적인 결과와 정보 활용에 따른 이득이 있을 것으로 예상되었다. 본 시스템을 활용할 경우 생산성 정보를 활용한 공사계획이 가능할 것이고 추후 정보가 지속해서 누적될 경우, 본 연구의 기대효과는 더욱 높아질 것으로 사료된다.

• 마케팅과학연구
• /
• 제19권2호
• /
• pp.53-67
• /
• 2009

For the last decades, service quality has been studied as one of the most important tools for a service company to compete with the other companies. Based on these past researches, it has been agreed that the service quality is a basic and powerful tool to create the competitive advantage. Due to similar reason, many service marketing practitioners have been also focused on the service quality to retain the existing consumers and collect the new consumers. However, service quality is subjectively perceived by individual consumers. Consumer evaluation of service quality can be different from each other. Especially consumers with one life-style may evaluate the service quality differently from the consumers with the other life-styles. Therefore we need to know whether there are differences in service quality perception on the categories of life-style. Life-style refers to a distinctive mode of living in its aggregate and broadest sense. It embodies the patterns that were developed and emerged from the dynamics of living in a society. Since the concept of life-style and its relationship to marketing was introduced in 1963 by William Lazer, methods of measuring the life-style and their application have been developed. Life-style has been usually used to segment the marketplace because it offers marketers a unique and important view of the market. When Life-style is combined with clustering methods, life-style segmentation can generate identifiable whole persons rather than isolated fragment. Life-style segmentation begins with people instead of products and classifies them into different life-style types, each characterized by a unique style of living based on a wide range of activities, interests, and opinions(Plummer, 1974). In this study we applies the life-style segmentation based on the AIO(Activities, Interests, and Opinions) to the consumers of the large discount stores. In Korea, the large discount store market has entered into maturity stage so that the market differentiation strategy is becoming a more critical issue to the marketing practitioners. One of the most important tools to differentiate from the competitors in large discount store market is continuously to provide service of better quality than competitors. This study tries to find answers about the following questions: 1) How can we categorize the consumer life-styles in the large discount store? 2) What are the characteristics of the categorized groups? 3) Are there any differences in service quality perception among the consumers with different life-styles 4) Are there any differences in consumer behavior among them in the large discount store? For the purpose, we collected survey data from consumers and analyzed the data with the SPSS package where we had $X^2$-test, factor analysis, ANOVA, MANOVA, and cluster analysis. The survey was made during one month in the April of 2008. Among the collected 306 copies of questionnaires, 281 copies were chosen as the effective samples for empirical analysis except 25 copies with wrong responses. To identify the life-style patterns, we used the measures employed by Kim and Kwon(1999), where 44 items on a seven-point scale were used to measure factors of the life-style patterns. The Principal Component Method was used for factor extraction, and the VARIMAX orthogonal factor rotation was employed. The 7 items showing low factor loading were eliminated. The results of the factor analysis suggested that nine factors of the life-style patterns were identified as follows: 1) the equality-of-sexes and pursuit-of-independence tendency 2) self-management tendency 3) sociable tendency 4) self-display tendency 5) degree of a dilettante life 6) pursuit-of-information tendency 7) bargain hunter tendency 8) TV preference tendency 9) pursuit-of-leisure tendency. Next, after the K-means cluster analysis was performed with nine factors of the life-style patterns, the life-styles of the respondents were classified into four groups which are named as the 'progressive practicality-oriented group', 'positive success-oriented group', 'sociable ostentation-oriented group', 'stable conservation-oriented group'. The analysis results for usage behavior between the market segments showed statistically significant differences in the frequency of usage, duration time in the store, consumer satisfaction, and loyalty. Also, we tried to investigate whether the large discount store consumers differently perceive the quality of service based upon the types of life-style. To measure the service quality of large discount store, we adapted several measurement models measuring the service quality such as SERVPERF, BCP, R-SERVPERF, R-BCP. MANOVA and One-Way ANOVA were performed to confirm the difference in service quality perception based on the market segments. The results have also shown significant differences between life-style types in service quality perception. These findings show that the large discount store marketers should consider consumer life-style as one of the most important market segments for marketing and understand the difference in service quality perception between life-style types. Our findings give important implications to marketers of large discount stores as well as life-style researchers. First, this study showed there were significant differences in consumer's service quality perception and usage behavior between the types of life-style. It provides evidence that the life-style approach can be a important basis in segmenting the large discount store market and will make consumers perceive the service quality high. Second, most previous researches on service quality have been in aggregate level. However, our results imply that the future research on service quality have to focus on segment level.

• 한국HCI학회:학술대회논문집
• /
• 한국HCI학회 2008년도 학술대회 2부
• /
• pp.152-157
• /
• 2008

모바일 무선인터넷 서비스(WAP)는 휴대폰이라는 제한된 화면 크기와 조작부, 브라우저 및 OS에서의 UI 구현상의 제약 등으로 인해 사용성이 고객만족도에 더욱 중요한 영향을 미치는 요소가 되고 있다. 특히 여러 다양한 콘텐츠 제공사에 의해 각각의 서비스가 개발되어 제공되는 현 상황에서, 이러한 서비스들의 UI 품질수준을 일관된 기준과 방법으로 효과적인 관리를 할 필요가 있다. 본 연구에서는 다양한 무선 인터넷 서비스들에 대한 일관된 UI 수준관리를 위한 사용성 지수 평가 체계를 제안한다. 제안된 평가 체계는 사용성 관련 사용성 지표와 UI 원칙으로부터 무선 인터넷 서비스에서의 UI 설계 요소와 평가 항목들을 도출하는 top-down 방식과, 기존 UI 설계 지침으로부터 사용성과 관계된 평가 항목들을 도출하고, 이들을 사용성 원칙과 지표 관점에서 그룹핑하는 bottom-up 방식을 통해 평가 체계 및 항목들이 구축되었다. 이러한 양방향 평가 체계 구축 방법은 사용성 문제를 야기할 수 있는 다양한 측면을 사용성 지표 관점에서 빠짐없이 고려할 수 있을 뿐 아니라, 실제 서비스 환경과 관련된 UI component 관점에서 구체적인 평가 항목들을 도출할 수 있다는 장점이 있다. 이러한 방법을 통해 구조화된 평가 체계는 사용성 지표와 각 지표와 관계된 사용성 원칙인 UI 가이드라인, 각 가이드라인 별로 구체적인 평가를 위한 UI component 별 평가항목들간 연결을 통해 계층적으로 구성되어 있다. 특히 각 평가 항목들을 O/X 로 판정할 수 있는 구체적인 내용과 형태로 구성하고, 전체 평가 항목 대비 만족된 평가항목의 비율로써 해당 서비스의 사용성 접수가 도출될 수 있게 하여 무선 인터넷 서비스의 사용성 수준을 정량적인 값으로 파악할 수 있도록 하였다. 제안된 평가 체계는 사용자 테스트를 통한 실제 사용성 문제와 비교 분석되어 그 효과별 검증하였으며, 평가 항목별로 평가 대상 및 기준, 사례를 안내해주고 지표별 접수를 자동으로 계산해 주는 S/W 로 구현되어 실제 무선 인터넷 서비스의 평가 및 개선작업에 적용되었다.

• 대한의료기공학회지
• /
• 제1권1호
• /
• pp.13-59
• /
• 1996

Dep. of Classics &Medical History, College of Oriental Medicint, Kyung Hee University Today, many people are more interested Today, many people are more interested in preventing the disease than curing it. Chi-Kung(氣功) is the way of Life-Cultivation(養生法) peculiar to the orient, it is reported in china that Chi-Kung has an excellent curative value not only in curing the disease but also in preventing it. But the full-scale study of Chi-Kung is not be made up to now in Korea, so I studied the developmental history of chinese Chi-Kung through the oriental medical books. From this study, I reached the following conclusions; 1. Chi-Kung is naturally derived from the self-preservation instinct to adapt oneself to circumstances of the nature, but in the investigation from the documentational records, it is originated in the treatment method of the Sam-Huang-O-Jae(三皇五帝) period to cure the abnormal circulation of the vital force and blood caused by damp(濕). 2. As the principle and the method of the Life-Cultivation of the Chun-Chu-Jeon-Kook(春秋戰國) period were recorded in Huang-Jae-Nai-Gyung(黃帝內經) detailly and the remedy examples by ancient Chi-Kung such as Tao-Yin(導引), Haeng-Chi(行氣) were presented, we considered that theoretical basis of the development of Life-cultivation and Chi-Kung study was furnished in that period. 3. A famous doctor, Hwa-Ta(華引) lived in Han dynasty, researched the theory and practice of Tao-Yin transmitted from the former generations, as that result, he formed a kind of medical, gymnastics what is called O-Keum-Hi(五禽?). It is considered that 'O-Keum-Hi' is a Tao-Yin method developed more practically and systemetically than the Tao-Yin appeared in the 'Jang-Ja'(莊子) or 'Hoy-Nam-Ja'(淮南子). 4. In Wui-Jin-Nambook-Jo(魏曺南北朝) periods, the contents of Chi-Kung were more abundant under the influence of Buddhism(佛敎) and Taoism(道敎). Galhong(葛洪), the author of 'Po-Bak-Ja'(抱朴子) arranged the ancient Chi-Kung method systematically first of all, Tao-Goeng-Gyung, the author of 'Yang-Seong-Yeun-Myung-Rok'(養性延命錄) recorded the 'Yook-Ja-Geul'(六字訣) first time. 5. There is a new development of Chi-Kung therapy in Soo-Tang-Odae(隋唐五代) periods, especially So-Won-Bang(巢元方), the author of 'Jey-Bang-Won-Hwu-Ron' collected almost all of the Chi-Kung method, for curing the disease formed before Soo(隋) period. From that fact, we supposed that Chi-Kung was utilized more widely in curing the disease. 6. 'So-Ju-Cheon-Hwa-Hu-Peob'(小周天火候法) was adopted as the best orthodox approach under the influence of Nae-Tan-Taoist(道敎內丹學波) in Song-Keum-Won(宋金元) periods, especially in the song dynasty, 'Pal-Dan-Geum'(八段錦) was appearde and assignment of six-Chi(六氣) for bowel and viscera in the 'Yook-Ja-Geul'(六字訣) was decided firmly, that is to say Lung-Si(肺-?), Heart-Kha(心-呵), Spleen-Hoa(脾-呼), liver-Hoe(肝-噓), Kidney-chui(賢-吹), Three-Burner-shi(三焦-?). 7. In Myung-Cheong(明淸) periods, The general practitioner applied the principle of 'Byun-Jeng-Ron-Chi(辨證論治) to the Chi-Kung field, and after Myung dynasty the style of doing 'Yook-Ja-Gyel'(六字訣) was developed to the moving style. 8. Today, in china, the study on the Chi-Kyung is being progressed constantly under the positive assistance of government, Chi-Kung-Hak(氣功學) has taking its place as a branch of study step by step. It is considered that the establishment of Chi-Kung-Hak Classroom(氣功學敎室) and Medical Chi-Kung Center(氣功療法室) for special and systematic research are needed, at the same time the settlement of institutional system for training the Chi-Kung technician(氣功師) is also needed.

• 대한예방한의학회지
• /
• 제7권1호
• /
• pp.17-28
• /
• 2003

We met results like the followings through the literatures and questionnaires about the tasks and solutions about the insurance fee of packed medical herbs. 1) It's turned out that 74.8% of herb doctors agrees to the insurance fee of packed medical herbs. However, in comparison with the same survey of the herb doctor association the percentage of general approval went somewhat lower, and especially the percentage of 'positive approval' became notably lower$(43.7%{\rightarrow}26.5%)$ and the percentage of 'active objection' raised about 2 times$(6.8%{\rightarrow}12.9%)$. Inquiring into the approval reasons on the insurance fee application of packed medical herbs some heads such as 'development toward treatment medical science' and 'decrease of publics burden' were higher than the one of 'management income and expenditure.' 2) As a result of the research, 36.0% of the patients and 42.8% of the residents recognized that the pay range of Chinese herb health insurance is narrow. They recognized that less people have the experiences of Chinese medical hospital use and internal application of the packed medical herbs as they are older, men rather than women. 85.4% of the patients and 74.9% of the residents agreed on the insurance pay of packed medical herbs. It's shown that they agree on the Chinese medical hospital use more as the economic standard is lower, on the insurance pay as they have ever taken the packed medical herbs. In the aspect of increase of insurance fee, 66.7% of the patients and 44.3% of the residents agreed on the insurance pay of packed medical herbs, and 18.1% and 36.1% disagreed on the insurance pay of packed medical herbs. The main objective reason why they disagree on the insurance pay of packed medical herbs was 'because the insurance fee goes up higher,' which answered 95.2% of the patients and 78.8% of the residents. 7.22% of the patients and 1.80% of the residents answered that they can pay more insurance fee in case of the insurance pay of packed medical herbs. However, in the priority order of the insurance pay, it hold the 5th position between 2 target research groups which was less than medical examination, charges for hospital accommodation and taking MRI. 3) According to the result of analysis about the cost of packed medical herbs, current practice price is 115,000 won and the average prime cost of a packed medical herb is 73,000 to 106,000 won. It's examined that the herb doctors regard that 95,000 won will be reasonable when the packed medical herb is payed in insurance. However, it was found out that the public generally thinks that the price would be appropriate on the level of 30,000 to 40,000 won and the percentage of the answers of 20,000 won to 30,000 was fairly high. 4) the central system of a prescription should be change into the central system of demonstration and the sick and wounded. 5) To solve this problem, the government should regulate it to pass by the circulation gradation of [importer, $peasantry{\rightarrow}manufacturer{\rightarrow}wholesaler{\rightarrow}distributor$(Chinese medical hospital, pharmacy dispensary of Chinese medicine)]And it should intervene into the quality and the circulation steps of Chinese medicine through 'the office or organization which is in charge of certification of Chinese medicine' and 'the office or organization which is in charge of the circulation of Chinese medicine.' And some actions such as simple severance, lavation, drying should be included into the conception of manufacture and the boundary between food and medical supplies should be made at a manufactory. And the regulation of standardized goods at one's own house should be improved so that, the peasantry can sell the materials of Chinese medicine only to the manufacturer. 6) In company with the insurance pay of packed medical herbs, the study about the separation of dispensary from medical practice in the Chinese medicine should be accomplished.

• Journal of Plant Biotechnology
• /
• 제42권3호
• /
• pp.215-222
• /
• 2015

본 연구는 무의 개화가 지연되는 형질을 갖는 'NH-JS1'과 조기개화 형질을 가진 'NH-JS2'계통을 대상으로 춘화처리에 의한 무의 개화 특성을 조사하였으며, 이러한 특성을 유발하는 개화관련 유전자의 발현 수준을 분석하였다. NH-JS1 과 NH-JS2 두 계통 모두 춘화처리가 없는 조건에서는($23{\pm}1^{\circ}C$, 12시간 광조건/12시간 암조건) 90일 동안 생육하였을 때는 개화하지 않았으며, NH-JS1계통의 경우, 개화 유도를 위해서는 최소 25일의 춘화처리가 필요하며, NH-JS2계통은 15일의 춘화처리에 의해 개화가 유도되는 특성을 보여 주었다. 또한, NH-JS1계통은 로제트 잎이 9장 이상일 때, NH-JS2계통은 7장 이상일 때 추대가 형성됨을 확인 할 수 있었다. 춘화처리에 의한 개화관련 유전자들의 유전자발현을 분석한 결과, 개화억제 유전자인 FLC와 FRI의 발현은 개화가 지연되는 계통인 NH-JS1에서 높은 반면, 개화를 촉진하는 유전자인 SOC1, LHY 그리고 CO의 발현은 조기개화 계통인 NH-JS2에서 높게 나타났다. 춘화처리에 의해 FLC의 발현억제를 유지하는 VRN1과 VRN2도 NH-JS1 계통에서 2배 이상 높게 발현됨을 확인하였다. 본 연구결과는 춘화처리 시 무의 개화관련 유전자들의 발현과 개화특성이 관련되어 있음을 시사하며, 이를 바탕으로 육종분야에서 무의 개화시기가 조절된 품종을 개발하는데 도움이 될 것으로 예상된다.

• 농촌지도와개발
• /
• 제7권1호
• /
• pp.121-136
• /
• 2000

This study reports on a comparison between the Korean diffusion of agricultural innovation or extension service and the cooperative extension service in the United States of America. It focuses on relevant differences between the two systems and provides recommendation for improvement of the Korean system to insure success in important areas related to the diffusion of agricultural innovations. After a comparative study on diffusion of innovations it is clear that: in order to have a productive agriculture that makes effective and efficient use of natural resources and helps achieve sustainability goals, a mechanism that delivers knowledge to agricultural communities must be established and maintained. This mechanism is clearly an agricultural extension service that is cooperatively funded by federal, state and local governments and that insures participation of constituents in the process of establishing priorities and evaluating achievements. The success of US agriculture, the most productive in the world, is to a large degree to the Cooperative Extension Service. Based on the results of this study and the differences of the United States and Korea, the following recommendations should be emphasized for more effective communication for agricultural innovation and rural development in Korea: 1) In order to insure that extension educators are high caliber professional individuals, it is important to establish a system that nationally recognizes these individuals as such, and that provides a professional development path. 2) The results of the decision of transfer of extension educators to local governments has not yielded positive outcomes, especially in terms of professional status. It is clearly demonstrable that valuable professionals are leaving the service, that local governments do not have the will and resources to implement a successful extension program. 3) Because of the critical importance of diffusing innovations to agricultural producers in order to insure and quality and steady food supply, it is of critical importance that these issues be addressed before the extension service is further deteriorated. Given the cement situation, it is clear that the extension service should become nationally supported again in cooperation with local and state governments and that extension professionals be given appropriate rank at the national level, commesurate with their peers in research and teaching. 4) The common current committee practice of lengthy reporting and short discussion needs to be changed to one that results in char, brief and substantive action oriented goals. Joint participation by researchers, extension educators and farmers should be encouraged in planning, implementation and evaluation of communication for agricultural innovations. Roles and functions of committees for institutional cooperation, and or agricultural extension committees should be enlarged. 5) Extension educators should be encouraged to adopt new communication technologies to improve their diffusion of innovations methods. Agricultural institutions and organizations should be encouraged to adopt farmer-first and or client-oriented approach in agricultural extension and diffusion of agricultural technologies. The number, complexity and rapid change of information in agricultural extension require the development of a computer based information and report system to support agricultural extension. 6) To facilitate and expand the further development of communication for agricultural innovation and rural development, agricultural communication programs in universities especially in colleges of agriculture and life sciences. 7) To strengthening the sense of national and social responsibility communication for agricultural innovation and rural development among students in agricultural colleges and universities through participation in learning activities by proactive recruitment. 8) To establish and reinforce a policy that insures participation in communication for agricultural innovation and regal development activities. 9) To improve further development of communication for agricultural innovation and rural development in Korea, more research activities should be encouraged.

• 한국산림과학회지
• /
• 제106권2호
• /
• pp.130-149
• /
• 2017

기후변화에 취약한 한반도 아고산대는 한대성 북방계식물의 서식처이다. 본 연구는 아고산대 산림의 군집생태학적 접근을 통한 복원 및 관리방안의 기초자료 제공목적으로 설악산 대청봉 일대 산림식생의 군집구조 및 식물상을 구명하였다. 2016년 5월부터 10월까지 31개소의 식생조사를 실시하였고, 식물사회학적 식생유형분류, 중요치, CCA를 분석하였다. 그 결과 식생유형분류체계는 분비나무군락에서 군단위로 눈잣나무군, 만병초군, 바디나물군, 이상 총 3개의 식생유형(VU)으로 분류되었다. 식별종군으로는 눈측백 식별종군, 자주솜대 식별종군을 포함하여 총 7개 종군유형으로 분류되었다. 평균 상대우점치 분석(MIP) 결과, VU 1의 MIP는 잣나무(24.1), 분비나무(23.6), 사스래나무(10.5) 등, VU 2의 MIP는 잣나무(26.2), 분비나무(20.8), 사스래나무(10.5) 등, VU 3의 MIP는 잣나무(22.2), 분비나무(16.4), 사스래나무(13.5) 등의 순이었다. 층위별 주요 경쟁수종인 잣나무와 분비나무의 중요치는 VU 1의 교목층에서 잣나무가 46.7, 분비나무는 26.1로 잣나무가 우세하나 아교목층, 관목층, 초본층에서는 분비나무의 중요치가 잣나무에 비해 높았고, VU 2와 VU 3에서도 교목층은 잣나무의 중요치가 높았지만 아교목층 이하에서는 낮은 값을 나타냈다. CCA ordination 분석 결과, 눈잣나무군은 해발고, 바디나물군은 출현종수와 다소 정의 상관관계를 가지는 것으로 나타났다. 산림청 지정 특산식물은 11분류군, 희귀식물은 24분류군으로 북방계 식물의 비율이 62.5%로 나타났다. 결론적으로 본 연구에서 분류된 3개의 식생단위와 분비나무 및 잣나무의 층위별 중요치 변화에 대한 식생학적 접근의 장기 모니터링이 필요하고, 희귀특산식물에 대한 개체군 및 군집생태학적 관리가 필요할 것으로 사료되었다.

• 한국식품영양과학회지
• /
• 제42권8호
• /
• pp.1183-1189
• /
• 2013

연구에서는 굴 패각 추출물이 papain으로 유도된 골관절염 동물 모델에 미치는 영향을 살펴보았다. 8주령의 C57BL/6J 마우스 우측 슬관절강에 papain $6{\mu}L$를 투여하여 골관절염을 유발하였다. 실험군은 각 군당 체중이 고르게 8마리씩 배정하여 총 다섯군으로 분류하였다. 정상군은 우측 슬관절강에 생리식염수 $6{\mu}L$ 주사하고 20일간 1일 1회 생리식염수 0.2 mL씩 경구투여 하였다. 대조군, 약물투여군, 굴 패각 추출물 투여군은 골관절염을 유발 후 각각 생리식염수, diclofenac sodium 2 mg/kg/bw, OSE 100, 200 mg/kg/bw를 20일 동안 매일 1회 정해진 시간에 경구투여 하였다. 실험기간 동안 체중을 측정하였으며, 실험 20일에 부검하여 슬관절의 병리조직학적 관찰, 관절연골 내 proteoglycan 함유율, 골관절염 지수의 변화, 혈액내 TNF-${\alpha}$, IL-$1{\beta}$, IL-6 함량을 측정하였다. 체중은 실험기간 동안 모든 개체 간의 유의적 차이가 없었다. 관절연골 내 proteoglycan 함유율은 DS 및 OSE 투여군이 papain 투여 대조군보다 유의성(P<0.05)있게 높았으며, 특히 OSE-200 투여군은 약물 투여군과 유사한 proteoglycan 함유율을 나타냈다. H&E 염색을 통하여 관찰한 결과, 골관절염이 유발된 마우스에 굴 패각추출물을 경구 투여하였을 때 관절연골의 파괴와 골 침식 등 연골의 변성이 약물 처리군과 유사한 것을 보아 굴 패각 추출물이 골관절염 치료에 효과가 있는 것을 확인할 수 있었다. 병리조직학적으로 골관절염 지수는 DS 및 OSE 투여군이 papain 투여 대조군보다 유의성(P<0.05) 있게 낮았으며, OSE-200 투여군이 OSE-100 투여군보다 낮았다. 혈액 내 TNF-${\alpha}$, IL-$1{\beta}$, IL-6 함량은 papain 투여 대조군이 정상군에 비해 유의적(P<0.05)으로 증가하였으며, DS 및 OSE 투여군은 대조군보다 유의성(P<0.05) 있게 낮았다. 특히 TNF-${\alpha}$ 및 IL-6 함량은 OSE-200 투여군이 약물 투여군과 유사한 감소 효과를 나타내었다. 이와 같은 결과는 굴 패각 추출물이 papain으로 유도된 골관절염에서 연골의 변성을 줄이고 염증을 억제함으로써 골관절염 치료에 효과가 있는 것으로 사료된다. 굴 패각은 탄산칼슘이 풍부하기 때문에 골관절염 개선에 효과가 있는 것으로 사료되나, 굴 패각 추출물 중 어떠한 기능성 물질이 골관절염 개선 효과를 나타내었는지에 대해 향후 심도 있는 연구가 필요하다.

• 성인간호학회지
• /
• 제12권3호
• /
• pp.431-451
• /
• 2000

In this paper, I will examine the variables influencing the Quality of Life of arthritis patients and present basic materials which help arthritis patients have positive thinking in life and ultimately lead a satisfactory life. The subjects for this study are 231 inpatients and outpatients with arthritis living in J and K city in Chonbug Province. For the analysis of collected data I employed the SAS program. The variables for characteristics and the quality of life were analysed by descriptive statistics, T-test and ANOVA, and the relations among variables were analysed through Pearson Correlation; the Regression method was employed to predict the factors affecting quality of life. For the validity of reliance on measuring equipment Cronbach Alpha was used. The results of the study are as follows : (1) The mean score of quality of life of arthritis patients is 3.09(5 in the maximum). The general characteristics which affect the quality of life are age(F=5.13, p=0.0006), standard of education(F=6.49, p=0.0003), marriage status(F=7.77, p=0.0005), monthly pay(F=4.37, p=0.0020), medical benefits (F=4.85, p=0.0087), and supports(F=4.39, p=0.0050). For the disease-related characteristics, there is a significant difference in the 6 items: pain control method(F=5.92, p= 0.0002), physical therapy(F=3.25, p=0.013), whethere or not patients exercise(F=4.62, p=0.0000), regularity of exercise(F=4.79, p=0.0000), frequency of exercise(F=6.29, p=0.0001), and amount of exercise(F=4.62, p=0.0043). Depending on the type of arthritis, there is also a significant difference in the degree of pain felt. The patients with infectious arthritis suffer from pain the most, followed by those with gout, rheumatism and degenerative arthritis, in that order. Although statistics don't show any convincing evidence, those with gout perceive that they are in best health condition, followed by those with rheumatism, degenerative arthritis, and infectious arthritis, in that order(F=2.23, p=0.0669). (2) The quality of life of arthritis patients is correlated positively with perceived health status(r=0.56, p=0.0001), health promoting behavior(r=0.53, p=0.0001), family support (r=0.46, p=0.0001), amount of exercise (r=0.36, p=0.0001), ADL(r=0.36, p=0.0001), HLOC(r=0.32, p=0.0001), frequency of exercise(r=0.32, p=0.0001)in that order, while correlated negatively with the degree of pain felt(r=-0.32, p=0.0001), the number of pain regions(r=-0.19, p= 0.0041), and the duration of pain(r=-0.14, p=0.0279). (3) Regression analysis reveals that the most powerful predictor of the quality of life is perceived health status, which account for 31.11%. The other predictors of the quality of life, which account for 60.22%, are health promoting behavior(16.51%), family support(3.81%), ADL(2.52%), gender(1.86%), the number of family members(1.36%), level of pain(1.24%), duration of pain (1.08%), and level of education(0.67%). The results of the study show that perceived health status and health promoting behavior are the two most important variables. However, considering that the perceived health condition is difficult to control by nursing intervention, it is suggested that the level of expectation for patients, must be decided first, and the health promoting behavior and the family support influencing the quality of life must be taken into account as targets for nursing intervention. As a way of controlling the quality of life, I think that a more comprehensive approach comprising the above important variables along with demographic and general characteristics is needed. I also suggest that we must continue to explore the variables affecting the quality of life and include those variables in nursing intervention.