• 대한방사선기술학회지:방사선기술과학
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• 제38권3호
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• pp.267-276
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• 2015

최근, 초음파검사로 인해 악성잠재력을 지닌 담낭용종의 발견률이 높아지고 있다. 담낭용종의 위험인자에 대한 다양한 연구가 보고 되었지만 혈청 생화학, 생활습관을 포함한 대사증후군과 담낭용종과의 관계에 대한 연구는 미흡한 실정이다. 본 연구의 목적은 한국에서의 생활습관, 생화학적 혈액검사를 포함한 대사성증후군과 담낭용종인 자간의 상관관계를 알아보는데 있다. 2012년11월2일부터 2014년1월31일까지 경기도내 2차병원을 방문한 151명 남성과 167명 여성을 대상으로 검사를 실행하였다. 이들은 무작위로 차출되었고, 담낭용종 유무에 따른 다양한 변수를 비교하였으며, 수집된 데이터는 Windows 프로그램 SPSS version 20.0을 사용하여 분석하였다. 평균 담낭용종의 크기는 직경이 3.92mm이고 용종의 크기는 직경이 10mm 이하였다. 담낭용종이 발견된 사람은 총184명(57.9%), 그 중 대사성증후군 발견된 사람은 114명(26.4%)으로, 대사성증후군을 가진 사람들에게서 담낭용종의 발생률이 높아짐을 알 수 있었다. 담낭용종에 대한 위험요소에서 체중 1.061배, BMI에서 1.186배, 수축기혈압에서 1.060배, 이완기혈압에서 1.030배, 총콜레스테롤에서 1.009배, 대사성증후군에서 2.736배, 당뇨에서 1.011배, 적혈구침강속도ESR에서 1.064배 높음을 알 수 있었다. 담낭용종의 위험인자는 체중, BMI, 총콜레스테롤, 중성지방, 당뇨, 수축기혈압, 이완기혈압, 적혈구침강속도ESR, 그리고 대사성증후군임을 알 수 있었다. 이 연구는 담낭용종에 대한 연구의 중요한 연구 자료로 사용되고, 차후에 좀 더 대규모의 연구가 이루어져야 할 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1361-1364
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• 2012

Background: Results of screening colonoscopy from Western countries reported adenoma detection rates (ADRs) of 30-40% while those from Asia had ADR as low as 10%. There have been limited data regarding screening colonoscopy in Thailand. The objectives of this study were therefore to determine polyp and adenoma detection rates in Thai people, to evaluate the incidence of colorectal cancer detected during screening colonoscopy and to determine the endoscopic findings of the polyps which might have some impact on endoscopists to perform polypectomy. Materials & Methods: This study was a retrospective electronic chart review of asymptomatic Thai adults who underwent screening colonoscopy in our endoscopic center from June 2007 to October 2010.Results: A total of 1,594 cases were reviewed. The patients had an average age of $58.3{\pm}10.5$ years (range 27-82) and 55.5% were female. Most of the cases (83.8%) were handled by staff who were endoscopists. A total of 488 patients (30.6%) were reported to have colonic polyps. Left-sided colon was the most common site (45.1%), followed by right-sided colon (36.5%) and the rectum (18%). Those polyps were removed in 97.5% of cases and 88.5 % of the polyps were sent for histopathology (data lost 11.5%). Two hundred and sixty three cases had adenomatous polyps, accounting for 16.5 % ADR. Advanced adenomas were detected in 43 cases (2.6%). Hyperplastic polyps were mainly located distal to the splenic flexure of the colon whereas adenomas were found throughout the large intestine. Ten cases (0.6%) were found to have colorectal cancer. Four advanced adenomas and two malignant polyps were reported in lesions ${\leq}$ 5 mm. Conclusion: The polyp detection rate, adenoma detection rate, advanced adenoma detection rate and colorectal cancer detection rate in the screening colonoscopy of Thai adults were 30.9%, 16.5%, 2.6% and 0.6% respectively. Malignant transformation was detected regardless of the size and location of the polyps. Therefore, new technology would play an important role indistinguishing polyps.

• Tuberculosis and Respiratory Diseases
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• 제76권5호
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• pp.237-239
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• 2014

The early pulmonary consequences of inhalation injury are well documented; however, little is known about delayed pulmonary complications following thermal inhalation injury. Although thermal injury below the vocal cords is rare because of effective heat dissipation in the upper airway, inflammatory endobronchial polyps have previously been reported as a delayed complication associated with inhalation injury. We report an extraordinary case of tracheobronchial polyps in patients with smoke inhalation injury. This report shows the delayed development and natural course of tracheobronchial polyps following thermal injury.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5423-5425
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• 2014

Purpose: To evaluate the risk factors for endometrial hyperplasia concomitant endometrial polyps in pre- and post-menopausal women. Materials and Methods: A total of 203 patients undergoing endometrial sampling before hysterectomy were evaluated in this retrospective study. Data recorded were age, gravidity, parity, body mass index (BMI: weight(kg)/$height(m)^2$), endometrial thickness (ET), menopausal status, presence of adenomyosis and diabetes mellitus. Results: Endometrial hyperplasia and polyps were detected in 13 patients. There were statistically significant differences in terms of age, menopausal status, morbid obesity and diabetes mellitus (p<0.005). Logistic regression demonstrated that menopausal status and presence of diabetes mellitus were independent risk factors. Conclusions: According to the current study; menopause and diabetes mellitus are strong risk factors for the presence of concomitant endometrial polyps and endometrial hyperplasia.

• 한국산학기술학회논문지
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• 제15권3호
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• pp.1641-1649
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• 2014

본 연구는 대장 용종 발생의 위험인자를 파악하기 위해 종합검진 수검자 중 대장내시경 검사와 복부초음파검사를 동시에 시행 받은 508명을 대상으로 나이, 성별, 흡연, 음주, 운동의 일반적인 특성과 신장, 체중, 혈압, 허리둘레, 체질량 지수 등의 신체 계측을 하였으며, 동시에 채혈을 통한 공복 시 혈당과 여러 가지 혈액검사를 분석하였다. 그 결과 AST, ALT, 총콜레스테롤, 지방간, 비만도 및 흡연여부가 유의하게 높은 것으로 나타났으며 대장용종이 있는 대상자가 지방간과의 관련성이 3.4배로가 가장 높았고, 다음으로 총콜레스테롤 2.3배, 흡연자가 비흡연자에 비해 2.3배나 위험성이 높게 나타났다.

• 대한한방소아과학회지
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• 제13권1호
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• pp.191-204
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• 1999

Background: Nasal polyps are benign mass of nasal mucose, chronic sinusitis are swelling of nasal mucose, so nasal polyps and chronic sinusitis take a place at the same time. Nasal polyps are located lateral wall of nose, middle meatus, between middle nasal concha and inferior nasal concha. Objective: To demonstrate the effect of herbal medicine therapy in the chronic sinusitis and nasal polyps before and after treatment using computed tomography (CT). To compared before and after treatment of otitis media using earscope. Materials and methods: Five patients (4 mail and 1 femail) treated in our hospital between August 1998 and July 1999 were studied. Ages ranged from 9 to 23 years (mean age:13 years). All patients had a underlying family history, and past history(allergy or sinusitis of parents or brothers). Illness period was from 1 to 36 months (mean period:10.5 month). To ascertain the efficacy of treatment, CT were checked out. In the CT, three images were obtained 2cm interval on the coronal and axial plan. We classified treatment period into the type of allergic disease. Gamihyunggyeyungyo-tang was administered mainly. Gamigwaghyangjeungki-san, Gamizwakwi-eum and Gamihyangso-san were administered for through oral route additional symptoms. Results: Treatment period was from 126 to 157 days (mean period:140.7 days). To 3 patients with chronic sinusitis and nasal polyp, treatment period was 140.7 days, to 2 patients with otitis media and chronic sinusitis and nasal polyp, treatment period was 141.5 days. So they had no significance. Not nasal polyp from middle meatus, but also polypoid mucosal change of maxillary sinus is polyps Conclusion: We know that herbal medicine therapy is the effective treatment of pediatric chronic sinusitis and otitis media using earscope and CT. Herbal medicine therapy was effective in increasing immunity, inhibiting allergic reaction and inflammation of respiratory system. we practice ECP(eosinophil cataionic protein) and MAST examination, objectify herbal medicine therapy.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2401-2405
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• 2016

Background: Both colorectal cancer (CRC) and diverticular disease (DD) are common in the affluent West, and their prevalence is also increasing in the rest of the world with economic development. Both diseases have common epidemiologic characteristics; increasing incidence, more common with advancing age and related to specific dietary changes. However, studies of associations between the two have generated mixed results with some showing positive correlations, whilst others have shown no or negative links. Most of these studies have been from the West with study populations that were predominantly Caucasians. Here the focus was on DD and colorectal neoplasms, including CRC, in Brunei. Materials and Methods: All patients who had undergone complete colonoscopy between 2011 and 2014 were identified and retrospectively reviewed. Patients under the age of 18 years old or had previous colonic surgeries (including previous CRC resection) were excluded. Results: The total number of colonoscopies included in the study was 2,766 (mean age $53.2{\pm}14.8$ years old, male 51.8%), of which DD, CRC and colonic polyps were detected in 17.3%, 4.7% and 28.2% respectively. The proportions of DD, polyps and CRC increased proportionally with age (<30 years, 30-49, 50-69 and ${\geq}70$). Overall, there was no association between the presence of DD and CRC (3.6% vs. 5.0%, p=0.179) but there was a significant association between CRC and left sided DD (p=0.034 by trend). There were also a significant association between presence of DD and polyps (36.1% vs. 28.2%, p=0.001), in particular with right-sided and pan-DD (p=0.001 for trend). Conclusions: Our study showed that the prevalence of DD, CRC and polyps increases with age. There were significant associations between presence of left-sided DD with CRC and right-sided or pan-DD with colonic polyps. This suggests shared risk factors. Further studies are required to assess links in other countries of the Asian Pacific region.

• 한국산학기술학회논문지
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• 제17권2호
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• pp.386-393
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• 2016

최근, 복부초음파로 인해 담낭용종의 발견률이 높아지고 있다. 담낭용종의 위험인자에 대한 다양한 연구가 보고 되었지만 생화학검사, 생활습관을 포함한 대사증후군과 담낭용종의 관계에 대한 연구가 미흡한 실정이다. 본 연구의 목적은 생활습관, 생화학적 혈액검사를 포함한 대사증후군과 담낭용종과의 관련성을 알아보는데 있다. 2013년 1월부터 2013년 12월까지 건강검진 수진자 중 복부초음파검사를 시행 받아 담낭용종의 진단을 받은 596명을 대상으로 나이, 성별, 흡연, 음주, 운동의 일반적인 특성과 신장, 체중, 혈압, 허리둘레, 체질량 지수 등의 신체 계측을 하였으며, 동시에 채혈을 통한 공복 시 혈당과 여러 가지 혈액검사 및 대사증후군 여부를 분석하여 담낭용종과의 관계를 알아보았다. 그 결과 남성, 흡연자, 비음주자에서 유의하게 높았으며, 체질량지수가 높을수록, 대사증후군이 있는 집단이, HBsAg 양성군에서 높았고, 위험도는 남성이 여성보다 1.8배, 대사증후군이 있는 군이 없는 군보다 2.3배, HBsAg이 양성인 군에서 2.6배 높게 나타났다.

• Journal of Preventive Medicine and Public Health
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• 제38권4호
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• pp.415-419
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• 2005

Objectives : We wanted to evaluate the relationship between obesity and left colonic adenomatous polyps in Korean adult men. Methods : This study was conducted among 575 adults men (aged between 40 and 69), who had colonoscopy done from January to December 2002 during a routine health examination at Health Promotion Center, Ulsan University Hospital. The patients' colons were examined up to splenic flexure by using fiberoptic colonoscopy. A questionnaire survey on behavioral factors and physical measurements were also done. The body mass index (BMI) and waist-hip ratio (WHR) were used as the indices of obesity. The BMI was categorized into three levels: normal ($BMI{\leq}22.9$), overweight ($23{\leq}BMI{\leq}24.9$), and obese ($BMI{\geq}25.0$). The WHR was categorized into four levels with cutoff points at the 30th, 60th, and 90th percentile of the control group. Age, education, smoking, alcohol use and exercise were controlled for by performing multiple logistic regression analysis. Results : There were 99 cases of colonic adenomatous polyps. Four hundred seventy six subjects with normal colonoscopy findings served as the control. The BMI and WHR were associated with the adenomatous polyps (odds ratio, 1.81 [95% CI=1.02-3.19] for a $BMI{\geq}25.0$ as compared with a $BMI{\leq}22.9$, odds ratio, 3.94 [95% CI=1.77-8.77] for a $WHR{\geq}0.95$ as compared with a $WHR{\leq}0.86$). The BMI was not associated with the risk of adenomatous polyps after additional adjustment was made for the WHR, but the association between the WHR and adenomatous polyps was still positive and independent of the BMI (odds ratio, 4.15 [95% CI=1.63-10.59]). Conclusions : The results support that obesity, and particularly abdominal obesity, can be associated with an increased risk of incurring colonic adenomatous polyps.

• Clinical and Experimental Pediatrics
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• 제48권4호
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• pp.453-456
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• 2005

연장아에게서 장중첩증의 소견을 보일 경우 원인 질환이 있는지 의심해야 하며, 원인 질환을 찾도록 노력하여야 한다. 저자들은 심와부 통증과 구토로 내원한 10세 여아에게서 장중첩증으로 발현된 공장에 발생한 연소성 용종 1례를 경험하였다.