• Title/Summary/Keyword: Poly(acrylic acid)

Search Result 182, Processing Time 0.023 seconds

Subacute Toxicity Study of Poly(sodium acrylic acid-acrylic acid) in Rats (폴리(아크릴산소다-아크릴산)의 랫드에 대한 아급성 독성시험에 관한 연구)

  • 서경원;박기숙;한범석;장동덕;김창옥;김효정
    • Journal of Food Hygiene and Safety
    • /
    • v.8 no.2
    • /
    • pp.105-117
    • /
    • 1993
  • The objective of this investigation was to characterize the subacute toxic potency of orally administered poly(sodium acrylic acid-acrylic acid), super absorbent polymer. Four groups of rats were maintained on diets containing 0, 1.25, 2.5 or 5% of poly(sodium acrylic acid-acrylic acid). The mean dosages of poly(sodium acrylic acid-acrylic acid) were estimated to be 1025 mg/kg/day, 2009 mg/kg/day and 4728 mg/kg/day in the male groups. The estimated average dosages of poly(sodium acrylic acid-acrylic acid) in the female groups were 1011 mg/kg/day, 2088 mg /kg/day and 4576 mg/kg/day, respectively. Few test compound-related toxic effects were observed in body weight gain, clinical signs, hematological parameters and serum biochemical values. Urinalyses, gross necropsy and histopathology revealed no evidence of specific toxicity. Food and water consumption tended to increase in the animals fed the diet of 2.5% and 5%. Our data indicate that no-observed effect level of poly(sodium acrylic acid-acrylic acid) was estimated to be 1.25% in the diet (mean dosage: 1025 mg/kg/day in male rats, 1011 mg/kg/day in female rats).

  • PDF

Studies on the Addition of the Hydroquinonesulfonic Acid to Poly(vinyl alcohol)/poly(acrylic acid-co-maleic acid) Membranes to Improve the Ion Conductivity for Fuel Cell Applications (Poly(vinyl alcohol)/poly(acrylic acid-co-maleic acid) 이온교환막에 이온전도도 향상을 hydroquinonesulfonic acid 첨가 연구)

  • 임지원;황호상
    • Membrane Journal
    • /
    • v.14 no.1
    • /
    • pp.44-52
    • /
    • 2004
  • This paper concerns the development of a cationic polymeric membranes for direct methanol fuel cell. The crosslinked poly(vinyl alcohol) (PVA) membranes with poly(acrylic acid-co-maleic acid) (PAM) and hydroquinonesulfonic acid (HQSA) as the crosslinking agents were prepared according to the amount of crosslinking agents. The resulting membranes were characterized in terms of methanol permeability, proton conductivity, water content and ion exchange capacity. The methanol permeability and proton conductivity increased with increasing PAM content up to 9 wt% and then decreased. This trend is considered the effect of the cross linking rather than the introduction of hydrophilic groups. When the HQSA contents were varied, no interesting increases of proton conductivity, water content and ion exchange capacity were found.

Studies on Metal Complex Formation of Poly (styrene-co-Acrylic acid) (스틸렌-아크릴산계 공중합체의 금속착물 형성에 관한 연구)

  • Kim, Kong-Soo;Kim, Soo-Jong;Cho, Suk-Hyeong;Chun, Yong-Chul
    • Applied Chemistry for Engineering
    • /
    • v.2 no.1
    • /
    • pp.70-76
    • /
    • 1991
  • Water soluble poly(sulfonated styrene-co-acrylic acid) was polymerized with sulfonated styrene and acrylic acid in the presence of silver sulfate at $99^{\circ}C$ for 4 hrs. The complex formation of poly(sulfonated styrene-co-acrylic acid) with Cu(II) was carried out. The maximum absorption wavelength of the poly(sulfonated styrene-co-acrylic)-Cu(II) system at different pH values was observed at 274 nm and 295 nm. The reduced viscosity of the poly(sulfonated styrene-co-acrylic acid)-Cu(II) complex were measured in the various pH ranges. The formation constants and stability constants of poly(sulfonated styrene-co-acrylic acid)-Cu(II) complex were calculated from Bjerrum method. The changes of enthalpy, free energy and entropy in the above reaction were determined by Ringbom method.

  • PDF

Preparation and Investigation on Swelling and Drug Delivery Properties of a Novel Silver/Salep-g-Poly(Acrylic Acid) Nanocomposite Hydrogel

  • Bardajee, Ghasem Rezanejade;Hooshyar, Zari;Kabiri, Firozeh
    • Bulletin of the Korean Chemical Society
    • /
    • v.33 no.8
    • /
    • pp.2635-2641
    • /
    • 2012
  • Novel silver/salep-g-poly(acrylic acid) nanocomposite hydrogel were prepared in aqueous solution using poly(acrylic acid) grafted onto salep as a biopolymer based material. FT-IR spectra confirmed that poly(acrylic acid) (PAA) had been grafted onto salep in graft copolymerization reaction. TEM observations showed that silver nanoparticles have been uniformly dispersed in polymeric matrix. Effects of pH, acrylic acid (AA) amount and silver ion concentration on swelling capabilities were investigated. Results indicate that modifying AA and silver ion can improve swelling properties of the resultant nanocomposite hydrogel. pH response of this nanocomposite hydrogel in acidic and neutral pH made it suitable for drug delivery applications.

Kinetics of Isothermal Crystallization in Poly(ethylene oxide) and Poly(styrene-co-acrylic acid)Blends (Poly(ethylene oxide)/Poly(styrene-co-acrylic acid) Blends의 등온 결정화 속도에 관한 연구)

  • Lee, Sang-Cheol;Lee, Mu-Seong;Jo, Won-Ho
    • Korean Journal of Materials Research
    • /
    • v.1 no.3
    • /
    • pp.151-155
    • /
    • 1991
  • The kinetics of isothermal crystallization in blends of poly(ethylene oxide) (PEO) and poly(styrene-co-acrylic acid) (SAA) has been examined as a function of the blend ratio, the copolymer composition, and the crystallization temperature, based on the Avrami eauation. The Avrami exponents were mostly chose to 2, independent of the crystallization temperature. The crystallization rate of PEO in PEO/SAA blends decreased with the increase of SAA content. And also, the higher the acrylic acid content in the SAA copolymer, 7he slower the crystallization rate of PEO in the blends.

  • PDF

Synthesis and Characterization of Polystyrene-b-Poly(acrylic acid) Block Ionomer via Atom Transfer Radical Polymerization (원자 이동 라디칼 중합을 이용한 Polystyrene-b-Poly(acrylic acid) 블록 이오노머의 합성 및 분석)

  • 박계리;안성국;조창기
    • Polymer(Korea)
    • /
    • v.27 no.1
    • /
    • pp.17-25
    • /
    • 2003
  • Using atom transfer radical polymerization (ATRP), polystyrene macroinitiators and polystyrene-b-poly(t-butyl acrylate) (PS-b-P(tBA) block copolymers were synthesized by CuBr/PMDETA catalyst system in solution. After hydrolysis, polystyrene-b-poly(acrylic acid), amphiphilic block copolymers, were formed. Subsequent neutralization of polyacid block led to the block ionomers. The molecular weight of the synthesized PS-b-P(tBA) block copolymers was easily-controlled to 5000-10000 and their distributions were less than 1.2. The chemical structures of the synthesized block copolymers were characterized by $^1$H-NMR and FT-IR. In the DSC thermograms, $T_g$ appeared in the vicinity of 100 $^{\circ}C$ because of higher styrene content. In addition, the phase separation of the block ionomers was observed by TEM.

Immobilization of Lum,brokinase on the Surface of Polyurethane by using the Photoreactive Poly(acrylic acid) (광반응성 poly(acrylic acid)를 이용한 Lumbrokinase 의 polyurethane 표면 고정화 방법에 관한 연구)

  • 김현정;류은숙;김종원;민병구
    • Journal of Biomedical Engineering Research
    • /
    • v.20 no.6
    • /
    • pp.547-553
    • /
    • 1999
  • 생체재료로 사용되는 polyurethane(PU) 표면에 항혈전성 lumbrokinase(LK)를 고정함으로써 생체적합성을 향상시키고자하였다. 먼저 LK를 PU 표면에 고정하기 위한 가교제로서 4-azidoaniline hydrochloride와 poly(acrylic acid)를 이용하여 4-azidophenyl 작용기가 amido 결합으로 치환된 수용성, 광반응성 poly(acrylic acid)(PPa-II)를 합성하였다. H-nuclear magnetic reasonance spectrum(500MHz H-NMR)의 6-7 peak와 infrared spectrum (FT-IR) 의 2125.48 cm peak으로부터 PPA-II의 합성을 지원하였다. EH한 4-azidophenyl 작용기가 poly(acrylid acid) 잔기에 치환된 정도는 UV/VIS adpectrophotometric spectrum을 확인한 결과 11~14%임을 알 수있었다. 0.5 1및 5% PPA-II를 각각 광반응하여 얻은 PU는 39.5, 161.8 및 181.5 nmole/$\textrm{cm}^2$의 농도로 표면에 carvoxyl 작용기가 유도되었음을 알 수있었다. 0.05M KH2PO4 (pH 4.5) 용액에서 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide(EDC)를 촉매로 사용하여 LK를 PU표면에 amido 공유결합으로 고정하였으며, 이것은 지속적인 fibrinolytic 활성도를 보였다. PPA-II를 이용한 표면 개질 방법은 수용성 반응조건에서 이루어진다는 점과 광반응을 이용함으로써 특정부위에서의 표면개질이 가능하다는 점에서 그 응용가치가 크며 아울러 PU의 생체적합성을 향상시킬 수 있는 방법으로서 판단된다.

  • PDF

Acute Toxicity Study of Poly(sodium acrylic acid-acrylic acid) in Rats and Mice (랫드와 마우스에서 폴리(아크릴산 소다-아크릴산)의 급성 경구 독성 시험에 관한 연구)

  • 박기숙;서경원;김효정
    • Journal of Food Hygiene and Safety
    • /
    • v.8 no.2
    • /
    • pp.97-103
    • /
    • 1993
  • The acute toxicity of orally administered poly(sodium acrylic acid-acrylic acid), powerfully water-absorbent polymer, was el'aluated in Sprague-Dawley rats and feR mice. Rats and mice aging 6 weeks were gavaged with 0, 2.0, 3.0, 4.4, 6.7, or 10 g of poly(sodium acrylic acidacrylic acid)/kg in com oil. No animal died by treatment and any toxic symptom was not observed in the treated animals during 2 weeks. The body weight of the treated animals was not significantly different from the controls. The results of macroscopic examination on the organs of the treated animals revealed no abnormal findings. Therefore, it was concluded that poly(sodium acrylic acidacrylic acid) was practically non-toxic when it was orally administrated to rats and mice up to 10 g/kg, and its $LD_{50}$ was evaluated more than 10 g/kg in rats and mice.

  • PDF

Synthesis, Characterization and Swelling Properties of Chitosan/Poly(acrylic acid-co-crotonic acid) Semi-Interpenetrating Polymer Networks (Chitosan/Poly(acrylic acid-co-crotonic acid) Semi-IPN의 합성, 분석 및 팽윤거동)

  • Hosseinzadeh, Hossein;Alijani, Darioush
    • Polymer(Korea)
    • /
    • v.38 no.5
    • /
    • pp.588-595
    • /
    • 2014
  • A semi-interpenetrating polymer network (semi-IPN) hydrogel composed of crosslinked chitosan and poly (acrylic acid-co-crotonic acid) was prepared in the presence of glutaraldehyde (GA) as a crosslinker. Fourier-transform infrared, thermogravimetric analysis and scanning electron microscopy were employed to confirm the structure of the semi-IPN hydrogel. The swelling capacity of hydrogel was shown to be affected by the monomers weight ratio, chitosan content, initiator and GA concentrations. The results also indicated that the semi-IPN hydrogel had different swelling capacity at various pHs. Additionally, the swelling behavior of the hydrogel was investigated in aqueous solutions of NaCl, $CaCl_2$, and $AlCl_3$.

Preparation and Characterization of Poly(vinyl alcohol)/Poly(acrylic acid) Hydrogel by Radiation (방사선을 이용하여 제조한 poly(vinyl alcohol)/poly(acrylic acid) 하이드로젤의 제조 및 특성)

  • Park, Jong-Seok;Kim, Hyun-A;Choi, Jong-Bae;Gwon, Hui-Jeong;Lim, Youn-Mook;Nho, Young-Chang
    • Journal of Radiation Industry
    • /
    • v.5 no.4
    • /
    • pp.377-382
    • /
    • 2011
  • Poly(vinyl alcohol) (PVA) is an interesting material with good biocompatibility, high elasticity and hydrophilic chacrateristics. In this study, crosslinked hydrogels based on PVA, and poly(acrylic acid) (PAAc) were prepared by gamma-ray irradiation. PVA and PAAc powders were dissolved in deionized water, and then irradiated by a gamma-ray with a radiation dose of 50 kGy to make hydrogels. The hydrogels were then annealed in an oven at $120^{\circ}C$ for 10 min, 30 min and 50 min under nitrogen atmosphere. The properties of a hydrogel such as gel fraction, swelling behavior, thermogravimetric analysis (TGA) and adhesive strength as a function of PAAc content and annealing time were investigated. The gel fraction decreases with decreasing PAAc content and increasing annealing time. The thermal behaviors have shown different patterns according to the annealing time. The adhesive strength increases with increasing PAAc content.