• 한국산업정보학회논문지
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• 제20권3호
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• pp.19-28
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• 2015

스마트폰의 영상정보처리에 기반한 현장 진단기기 개발을 목표로 입자계수용 형광 smartscope와 DC 모터로 제어되는 입자정렬 시스템을 제작하였다. 크기가 작고 저렴한 비용으로 비전문가도 쉽게 다룰 수 있는 smartscope는 LED, 볼렌즈, 형광필터가 설치된 어댑터가 스마트폰 카메라 앞에 장착되어 전용 애플리케이션으로 형광입자와 형광염색된 백혈구를 계수할 수 있었다. 모터는 안드로이드 스마트폰의 블루투스 무선통신 기능을 통해 제어되었다. 나선형 미세유동채널이 축을 중심으로 회전하는 동안 백혈구와 크기가 유사한 입자가 정렬되는 현상을 관찰하였다. 모터로 회전 방향과 속도가 조절되는 입자 정렬 시스템은 많은 시간이 소요되는 수작업을 최소화하고 시료 전처리 과정을 자동화할 수 있으므로, smartscope와 통합될 경우 스마트폰을 이용한 현장진단기기에 활용될 수 있을 것이다.

• 한국임상수의학회지
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• 제28권1호
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• pp.108-112
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• 2011

In clinical settings, researchers often want to assess agreement between two measurements (or tests) of the same continuous variable. For example, when new point-of-care analyzer for testing blood glucose level were introduced clinicians need to compare results from standard or established laboratory method of measurement to those of new or point-of-care analyzer. The question in a method-comparison study would either of two different methods be used to measure the same variable equivalently. In this paper common misuse of statistical methodologies seen in the medical literatures such as correlation coefficient and paired t-test are discussed. The Bland-Altman technique has been widely used for this purpose and provides a graphic in presentation of the findings from a method-comparison study, with a mean value of measurement, this bias and the limits of agreement. For ease of application and interpretation of this technique we discussed the analysis procedure and illustrated with two worked examples. Finally, a number of alternative ways in which data can be analysed and reported in such studies were reviewed.

• Genomics & Informatics
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• 제19권3호
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• pp.30.1-30.8
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• 2021

Salmonella species are among the major pathogens that cause foodborne illness outbreaks. In this study, we aimed to develop a loop-mediated isothermal amplification (LAMP) assay for the rapid and sensitive detection of Salmonella species. We designed LAMP primers targeting the hilA gene as a universal marker of Salmonella species. A total of seven Salmonella species strains and 11 non-Salmonella pathogen strains from eight different genera were used in this study. All Salmonella strains showed positive amplification signals with the Salmonella LAMP assay; however, there was no non-specific amplification signal for the non-Salmonella strains. The detection limit was 100 femtograms (20 copies per reaction), which was ~1,000 times more sensitive than the detection limits of the conventional polymerase chain reaction (PCR) assay (100 pg). The reaction time for a positive amplification signal was less than 20 minutes, which was less than one-third the time taken while using conventional PCR. In conclusion, our Salmonella LAMP assay accurately detected Salmonella species with a higher degree of sensitivity and greater rapidity than the conventional PCR assay, and it may be suitable for point-of-care testing in the field.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.2781-2784
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• 2007

Early detection of a disease is important to tackle treatment issues in a better manner. Several diagnostic techniques are in use, these days; for such purpose and tremendous research is going on to develop newer and newer methods. However, more work is required to be done to develop cheap and reliable early detection techniques. Micro-fluidic chips are also playing key role to deliver new devices for better health care. The present study focuses on a review of recent developments in the interrogation of different techniques and present state-of-the-art of microfluidic sensor for better, quick, easy, rapid, early, inexpensive and portable POCT (Point of Care testing device) device for a particular study, in this case, bone disease called osteoporosis. Some simulations of the microchip are also made to enable feasibility of the development of a blood-chip-based system. The proposed device will assist in early detection of diseases in an effective and successful manner.

• 대한디지털의료영상학회논문지
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• 제10권2호
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• pp.33-37
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• 2008

To keep the online medical records available to anyone without constraint of time and space, introducing EMR (Electronic medical record), which is a clinical support management system. The purpose of this study is to develop interface standard of clinical test device. Integration and sharing of medical information is faced with enormous obstacles because medical organizations and associated companies are separately developing the interface. I hope that multi-function management system with workstation concept is operated to efficiently transmit clinical device result data based on this study. Transfer of precise medical result data available for decision making will improve quality of health care service.

• Journal of Trauma and Injury
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• 제36권3호
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• pp.210-216
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• 2023

Purpose: This preliminary retrospective cohort study analyzed the relationship between the parameters provided by sonorheometry device Quantra and the coagulation values obtained from standard venous blood samples in patients admitted in intensive care unit (ICU). Methods: We reviewed medical charts of 13 ICU adult patients in whom at least one coagulation study with Quantra was performed. The relationship between Quantra and laboratory data was analyzed with the Spearman rank correlation coefficient (rho). The 95% confidence interval (CI) was computed. A P-value <0.05 was considered statistically significant. Results: We collected 28 data pairs. Statistically significant moderate correlations were found for the following parameters: clot time (CT) and activated partial thromboplastin time (rho=0.516; 95% CI, 0.123-0.904; P=0.009; clot stiffness (CS) and the international normalized ratio (INR; rho=0.418; 95% CI, 0.042-0.787; P=0.039); INR and platelet contribution to CS (rho=0.459; 95% CI, 0.077-0.836; P=0.022); platelet count and platelet contribution to CS (PCS; rho=0.498; 95% CI, 0.166-0.825; P=0.008); and fibrinogen and fibrinogen contribution to CS (FCS; rho=0.620; 95% CI, 0.081-0.881; P=0.001). Conclusions: Quantra can provide useful information regarding coagulation status, showing modest correlations with the parameters obtained from laboratory tests. During diffuse bleeding, CT and FCS values can guide the proper administration of clotting factors and fibrinogens. However, the correlation of INR with CS and PCS can cause misinterpretation. Further studies are needed to clarify the relationship between Quantra parameters and laboratory tests in the critical care setting and the role of sonorheometry in guiding targeted therapies and improving outcomes.

• 보건교육건강증진학회지
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• 제11권2호
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• pp.33-47
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• 1994

AIDS preventional efforts need to be guided by well trained health care personnel especially by school nurses for the adolescents. This study was designed to get basic data about AIDS educational program development for school nurses. The objectives of this study were to 1) identify AIDS knowledg of school nurses 2) identify AIDS attitudes of school nurses and 3) identify association between AIDS knowledge and sociodemographic characteristics. Data were collected from 173 subjects in Chonbuk province. Self-reporting questionnaire were administered during the period from 1st of June to 30th of June, 1994. AIDS related knowledge was measured by using 44 questions on cause(3 items), testing(3 items), mode of transmission(15 items), clinical manifestations(5 items), treatment(3 items), prevention(5 items), complication(4 items), infection control(3 items) and Using resources(3 items). AIDS related attitudes were measured by five point Likert scales using 13 questions on perceived threats from AIDS crisis (4 items), perceived severity to AIDS(2 items), perceived needs about psychosocial care for HIV infected patients(3 items) and perceived educational needs of AIDS(4 items). The collected data were analyzed by SPSS/PC/sup +/, using percentages, Mean and S.D. descriptive purpose and t-test or F for comparing the variables. The major findings were as follows: 1. Respondents ranged in knowledge of AIDS between 0 and 44 with the 33.79 mean score. Percentage of correctly answered respondents to each categories - mode of transmission : 87.0% - clinical manifestation : 85.0% - cause : 82.5% - prevention : 81.5% - treatment : 76.1% - infection control : 72.8% - testing of HIV infection 71.8% - using community resourses : 50.9% - complication : 45.8% 2. The respondents' attitudes of AIDS The majority(70%) showed higher perceived threat The majority(91.3%) showed higher perceived severity to AIDS crisis As a whole, perceived needs about psychosocial care for HIV infected patients negative The majority (over 96.5%) showed highly perceived educational needs of AIDS. 3. The relationship between AIDS knowledge and each of those general character. AIDS knowledge shows significant difference with age(F=3.50, p<.016), years of professional experience(F=4.14, p<.007) and received lecture about AIDS(F=4.54, p<.000). There was no significant difference between AIDS knowledge and job satisfaction.

• 지역사회간호학회지
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• 제12권1호
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• pp.214-225
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• 2001

The purpose of this study is to compare the characteristics of the demented elderly and normal elderly over 65 staying at home in Seoul. Here, the demented elderly are defined as the aged who score under 20 on the MMSE-K testing. The subjects were 15.104 elders in home. The method is a cross-sectional study home visiting survey with questionnaires. Data analyses were conducted by using frequency, percentage, t-test and ANOVA procedures. Results are as follows: First, general characteristics such as sex, age, marriage, education, physical health, and family characteristics such as economic level and single living showed a significant variance between demented elderly and normal elderly. Second, the demented elderly showed a significantly high point of AD and IADL. Third, in contrast with normal agents, the dementia showed a high need for assistance from the care giver but followed the same pattern. In conclusion, the above findings suggested that a social support system should be developed for the demented elderly and care givers in the home.

• 한국보건간호학회지
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• 제17권2호
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• pp.255-265
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• 2003

This study was conducted to provide a baseline data for hospice nurses to improve their practices for the spiritual wellbeing of their clients. Analysis of the spiritual wellbeing status of hospice patients was conducted from April 20 to June 20, 2002. A total of 59 cancer patients who admitted to hospice care units of one university medical center, and who have alert mental status were recruited for the study. Paloutzian and Ellison (982) spiritual wellbeing scale and Jungho Kang (996) scale, which was modified for the cancer patients, were used as the study instruments, ANOVA and T-test were applied using SPSS win 10.0 for statistical analysis. The results are as follows : 1. The mean spiritual wellbeing score of the hospice patients was $49.76(SD\pm7.95)$. When it was converted into 4 point scale, the mean score for the spiritual wellbeing was 2.49. The mean religious wellbeing score was $24.17 (SD\pm5.56)$ and that of the existential wellbeing was $25.59 (SD\pm3.10)$. 2 The mean score for the total spiritual wellbeing was $52.54 (SD\pm8.12)$ for female, and $47.86 (SD\pm6.95)$ for male and the difference was statistically significant (t=-2.305, p=.025), 3. In testing the spiritual wellbeing, there was significant difference according to the religion (F=28.931, p=.000). 4. In testing the religious wellbeing, the mean score was $22.77 (SD\pm5.35)$ for male, and $26.20 (SD\pm5.32)$ for female and the difference was statistically significant (t=-2.430, p=.019). 5. In testing the religious wellbeing, there was significant difference according to the religion (F=37.522, p=.000). However, the religious wellbeing was not different according to the age, occupation, marital status and education level. 6. In testing the existential wellbeing. there was significant difference according to the religion (F=8.147, p=.000). However, mean score for the existential wellbeing was not significantly different according to sex, age, occupation, marital status and education level. 7. In testing the existential wellbeing, there was significant difference according to the level of vigor (F=3.662, p=.032), while no difference was observed in the existential wellbeing according to the general health status, degree of pain, and diagnosis. From the results described above it can be concluded that : To improve the spiritual wellbeing status of hospice patients, hospice nurses should identify spiritual needs of the patients according to the religion. gender and the level of vigor.

• 기본간호학회지
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• 제5권2호
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• pp.313-323
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• 1998

This study was a descriptive research on the level of self-care available to continous ambulatory peritoneal dialysis patients (hereinafter referred to as 'CAPD patient') related to the specific area of infection management. The method employed for the collection of data was a modified instrument of the self-care survey essentially based on Young Sook Choi's instrument. The relevant data was collected from september 1, 1996 to september 30, 1996. The subjects were provided with an open-ended question regarding the reasons behind why they did not seek self-care. The answers provided about self-care compliance were analyzed by SPSS for frequency, percentage, mean, t-test, ANOVA. Reasons for non-compliance were analyzed by content analysis. The results of the study were as follows : 1. The percentage of patients engaging in self-care were according to the following self performed tasks : preparation of dialysis : 30.58 points Dialysate exchange procedures : 49.40 points - Two bag type : 50.50 points - Spike type : 48.80 points - Neo type : 48.90 points Catheter exit site care : 25.13 points More specifically, in relation to the preparation of dialysis as referred to above, those patients engaging in self care was relatively high with respect to the cleaning of the dialysis before use and for the preservation of peritosol. However, in dialysate exchange procedures, data revealed that those patients engaging in self-care are relatively low with respect to putting on a mask during the performance of peritosol exchange. Similary in peritosol exchange procedure and catheter exit care, low levels of self-care performance were found in the area of putting on a mask during the peritosol exchange procedures and catheter line testing procedures, respectively. 2. In general characteristics, there appeared to be no distinction in self-care compliance among CAPD patients. 3. The main reasons for non-compliance were based in the following factor : intellectual, attitude, enviromental surrounding and physical. As a result of the foregoing finding, nurses should provide adequate assistance to promote self-care compliance by CAPD patients by checking the preparation of dialysis, dialysate exchange procedure, and catheter exit site care which recieved low point in this research.