• 제목/요약/키워드: Plasma Diagnosis

검색결과 345건 처리시간 0.026초

폐색전증의 진단에 있어 혈청 D-dimer 측정의 진단적 가치 (Plasma D-dimer Determination in the Diagnosis of Pulmonary Embolism)

  • 임채만;김홍규;최강현;이상도;고윤석;김우성;장재석;김동순;김원동
    • Tuberculosis and Respiratory Diseases
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    • 제43권1호
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    • pp.69-74
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    • 1996
  • 연구배경: 폐색전증의 진단에 있어 확전법인 폐동맥 조영술은 관혈적이고 임상에서의 제약이 있으며, 폐환기-관류주사는 비고확률 소견인 경우 진단적 민감도 및 특이도가 낮은 문제가 있다. 혈장 D-dimer는 섬유소분 해산물로 임상적으로 폐색전증이 의심되는 환자에서 증가되는 것이 알려져 있어 혈장 D-dimer의 측정이 폐색전증에 있어 어떤 진단적 가치가 있는지 알아보고자 하였다. 방법: 전향적 임상연구로 정상대조군 21예와 폐색전증 환자군 9예에서 latex agglutination법에 의해 혈장 D-dimer를 측정하고 폐동맥조영술 결과와 비교하였다. 결과: 1) 대조군 및 폐색전증군의 혈장 D-dimer치; 대조군의 혈장 D-dimer치는 21예중 0.5 mg/L 미만 11예, 0.5 mg/L 보다 높은 경우 10예 였고, 폐색전증군 9예중 0.5 mg/L 미만 1예, 0.5 mg/L 보다 8예로 혈장 D-dimer치가 0.5 mg/L 이상으로 증가된 양성율은 폐색전증군에서 대조군에 비해 유의하게 많았다(p=0.049). 2) 혈장 D-dimer치의 진단적 효용; 혈장 D-dimer치 0.5 mg/L를 cut-off으로 했을 때 폐색전증 진단의 민감도 88.9%(8/9), 특이도 52.4%(11/21), 양성예측치 44.4%(8/18) 및 음성 예측치 91.7%(11/12)였다. 결론: 폐색전증의 진단에 있어 D-dimer의 측정치가 cut-off(0.5 mg/L)치 이내인 경우 폐색전증의 존재 가능성은 매우 적을 것으로 사료되었다.

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In-situ Process Monitoring Data from 30-Paired Oxide-Nitride Dielectric Stack Deposition for 3D-NAND Memory Fabrication

  • Min Ho Kim;Hyun Ken Park;Sang Jeen Hong
    • 반도체디스플레이기술학회지
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    • 제22권4호
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    • pp.53-58
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    • 2023
  • The storage capacity of 3D-NAND flash memory has been enhanced by the multi-layer dielectrics. The deposition process has become more challenging due to the tight process margin and the demand for accurate process control. To reduce product costs and ensure successful processes, process diagnosis techniques incorporating artificial intelligence (AI) have been adopted in semiconductor manufacturing. Recently there is a growing interest in process diagnosis, and numerous studies have been conducted in this field. For higher model accuracy, various process and sensor data are required, such as optical emission spectroscopy (OES), quadrupole mass spectrometer (QMS), and equipment control state. Among them, OES is usually used for plasma diagnostic. However, OES data can be distorted by viewport contamination, leading to misunderstandings in plasma diagnosis. This issue is particularly emphasized in multi-dielectric deposition processes, such as oxide and nitride (ON) stack. Thus, it is crucial to understand the potential misunderstandings related to OES data distortion due to viewport contamination. This paper explores the potential for misunderstanding OES data due to data distortion in the ON stack process. It suggests the possibility of excessively evaluating process drift through comparisons with a QMS. This understanding can be utilized to develop diagnostic models and identify the effects of viewport contamination in ON stack processes.

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Ar 가스 압력에 따른 유도결합형 플라즈마의 전자 밀도 측정 (Electron Density Measurement of Inductively Coupled Plasma by Ar Gas Pressure)

  • 이영환;김광수;조주웅;박대희
    • 대한전기학회논문지:전기물성ㆍ응용부문C
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    • 제52권11호
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    • pp.508-511
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    • 2003
  • In this paper, electrical characteristics of inductively coupled plasma in an electrodeless fluorescent lamp were investigated using a Langmuir probe with a variation of argon gas pressure. The RF output was applied in the range of 5 ∼ 50 (W) at 13.56 (MHz). The internal plasma voltage of the chamber and the probe current were measured while varying the supply voltage to the Langmuir probe in the range of -100 (V) ∼+100 (V). When the pressure of argon gas was increased, electric current was decreased. There was a significant electric current increase from l0W to 30 〔W〕. Also, when the RF power was increased, electron density was increase. This implies that this method can be used to find an optimal RF rower for efficient light illumination in an electrodeless fluorescent lamp.

Prepartal Decrease in Plasma Total Cholesterol Concentration in Dairy Cows Developed Subclinical Ketosis

  • Ro, Younghye;Choi, Woojae;Kim, Hoyung;Kim, Danil
    • 한국임상수의학회지
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    • 제34권3호
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    • pp.222-224
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    • 2017
  • A retrospective study was designed to determine whether there were any differences in prepartal blood biochemical parameters between cows developed subclinical ketosis (SCK) and non-SCK cows. Data on blood biochemistry from 33 Holstein parturient cows (15 SCK and 18 non-SCK cows) in one farm for one year, were compared. Plasma beta-hydroxybutyrate, non-esterified fatty acid and glucose concentrations were utilized in the diagnosis of SCK and showed significant differences between SCK and non-SCK cows after calving. Before calving, however, only plasma total cholesterol concentration in SCK cows was significantly lower than that in non-SCK cows. Consequently, it seems that lower plasma total cholesterol concentration before calving is related to the occurrence of SCK immediately after calving.

유도결합형 제논 플라즈마의 전자온도, 밀도 특성 (Properties of Electron Temperature and Density in Inductively Coupled Plasma of Xenon)

  • 허인성;양종경;이종찬;박대희
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2005년도 춘계학술대회 논문집
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    • pp.41-45
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    • 2005
  • In this paper, parameters of electron temperature and density for the mercury-free lighting-source were measured to diagnosis and analyze in Xe based inductively coupled plasma(ICP). In results at several dependences of 20~100 mTorr Xenon pressure, 50~200W RF power and horizontal distribution were especially mentioned. When Xe pressure was 20mTorr and RF power was 200W, the electron temperature and density were respectively 3.58eV and $3.56{\times}10^{12}cm^{-3}$. The key parameters of Xe based ICP depended on Xe pressure more than RF power that could be verified. A high electron temperature and low electron density with a suitable Xe pressure are indispensible parameters for Xe based ICP lighting-source.

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Diagnosis of Plasma Equipment using Neural Network and Impedance Match Monitoring

  • Byungwhan Kim
    • KIEE International Transaction on Systems and Control
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    • 제2D권2호
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    • pp.120-124
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    • 2002
  • A new methodology is presented to diagnose faults in equipment plasma. This is accomplished by using neural networks as a pattern recognizer of radio frequency (rf) impedance match data. Using a match monitor system, the match data were collected. The monitor system consisted mainly of a multifunction board and a signal flow diagram coded by Visual Designer. Plasma anomaly was effectively represented by electrical match positions. Twenty sets of fault-symptom patterns were experimentally simulated with variations in process factors, which include rf source power, pressure, Ar, and $O_$2 flow rates. As an input to neural networks, two means and standard deviations of positions were used as well as a reflected power. Diagnostic accuracy was measured as a function of training factors, which include the number of hidden neurons, the magnitude of initial weights, and two gradients of neuron activation functions. The accuracy was the most sensitive to the number of hidden neurons. Interaction effects on the accuracy were also examined by performing a 2$^$4 full factorial experiment. The experiments were performed on multipole inductively coupled plasma equipment.

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단일탐침법을 사용한 평판형 광원의 제논 (Xe) 플라즈마 특성 연구 (Xe Plasma Property with Flat Lamp by Langmuir Probe)

  • 백광현;이종찬;황명근;최용성;박대희
    • 대한전기학회논문지:전기물성ㆍ응용부문C
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    • 제55권1호
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    • pp.50-54
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    • 2006
  • The study on discharge of the flat lamp lighting source has been requested increasingly. To improve the brightness, life time and efficiency of flat lamp, the plasma diagnosis of flat lamp lighting source is very important. When a distance of discharge electrode is 5.5mm and width is 16.5mm, we measured electron temperature and electron density with single Langmuir probe in flat lamp. Pressure conditions to test the plasma discharge from 100 Torr to 300 Torr. The power supply was PDS-4000 with frequency 20kHz and duty ratio $20\%.$ Form these experimental results, electron temperature was decreased according to increase the gas pressure and the voltage while electron density was increased.

유도결합형 제논의 가스압력 및 RF전력에 따른 플라즈마의 전기적 특성 (Electrical Properties of Plasma According to Gas Pressure and RF Power of Xe-Inductively Coupled Plasma)

  • 최용성;이경섭
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 추계학술대회 논문집 광주전남지부
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    • pp.43-47
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    • 2006
  • In this paper, parameters of electron temperature and density for the mercury-free lighting-source were measured to diagnosis and analyze in Xe based inductively coupled plasma (ICP). As results at several dependences of 20~100mTorr Xenon pressure, the brightness of discharge tube was higher (4,900 $cd/m^2$) than other conditions when Xe pressure was 20mTorr and RF power was 200W. In that case, the electron temperature and density were 3.58eV and $3.56{\times}10^{12}cm^2$, respectively. The key parameters of Xe based ICP depended on Xe pressure more than RF power that could be verified. A high electron temperature and low electron density with a suitable Xe pressure are indispensible parameters for Xe based ICP lighting-source.

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1H-Nuclear Magnetic Resonance-Based Plasma Metabolic Profiling of Dairy Cows with Fatty Liver

  • Xu, Chuang;Sun, Ling-wei;Xia, Cheng;Zhang, Hong-you;Zheng, Jia-san;Wang, Jun-song
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권2호
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    • pp.219-229
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    • 2016
  • Fatty liver is a common metabolic disorder of dairy cows during the transition period. Historically, the diagnosis of fatty liver has involved liver biopsy, biochemical or histological examination of liver specimens, and ultrasonographic imaging of the liver. However, more convenient and noninvasive methods would be beneficial for the diagnosis of fatty liver in dairy cows. The plasma metabolic profiles of dairy cows with fatty liver and normal (control) cows were investigated to identify new biomarkers using $^1H$ nuclear magnetic resonance. Compared with the control group, the primary differences in the fatty liver group included increases in ${\beta}$-hydroxybutyric acid, acetone, glycine, valine, trimethylamine-N-oxide, citrulline, and isobutyrate, and decreases in alanine, asparagine, glucose, ${\gamma}$-aminobutyric acid glycerol, and creatinine. This analysis revealed a global profile of endogenous metabolites, which may present potential biomarkers for the diagnosis of fatty liver in dairy cows.

Identification of plasma miRNA biomarkers for pregnancy detection in dairy cattle

  • Lim, Hyun-Joo;Kim, Hyun Jong;Lee, Ji Hwan;Lim, Dong Hyun;Son, Jun Kyu;Kim, Eun-Tae;Jang, Gulwon;Kim, Dong-Hyeon
    • 한국동물생명공학회지
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    • 제36권1호
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    • pp.35-44
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    • 2021
  • A pregnancy diagnosis is an important standard for control of livestock's reproduction in paricular dairy cattle. High reproductive performance in dairy animals is a essential condition to realize of high life-time production. Pregnancy diagnosis is crucial to shortening the calving interval by enabling the farmer to identify open animals so as to treat or re-breed them at the earliest opportunity. MicroRNAs are short RNA molecules which are critically involved in regulating gene expression during both health and disease. This study is sought to establish the feasible of circulating miRNAs as biomarkers of early pregnancy in cattle. We applied Illumina small-RNA sequencing to profile miRNAs in plasma samples collected from 12 non-pregnant cows ("open" cows: samples were collected before insemination (non-pregnant state) and after pregnancy check at the indicated time points) on weeks 0, 4, 8, 12 and 16. Using small RNA sequencing we identified a total of 115 miRNAs that were differentially expressed weeks 16 relative to non-pregnancy ("open" cows). Weeks 8, 12 and 16 of pregnancy commonly showed a distinct increase in circulating levels of miR-221 and miR-320a. Through genome-wide analyses we have successfully profiled plasma miRNA populations associated with pregnancy in cattle. Their application in the field of reproductive biology has opened up opportunities for research communities to look for pregnancy biomarker molecules in dairy cattle.