• The Korean Journal of Nuclear Medicine
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• v.33 no.6
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• pp.519-526
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• 1999

Purpose: This study was designed to evaluate the usefulness of a technetium-99m mercaptoacetyltriglycine (Tc-99m MAG3) single photon emission computed tomography (SPECT) performed on transplanted kidney. Materials and Methods: Thirty renal transplant patients were included in this study. Planar scan was performed for 30 minutes using 555 MBq Tc-99m MAG3. A post-voiding SPECT scan was acquired on the third, seventh, fourteenth and twenty eighth day after transplantation. Results: SPECT scan showed interpretable image quality in 26 of 30 patients (86.7%) and 84 in 120 scans (70%). Fourteen of 26 patients with interpretable SPECT image showed decreased or increased radioactivity, but only 5 had abnormal findings on the planar scan. Focal SPECT defects were seen in allografts with normal function (n=3), acute tubular necrosis (n=3), and acute rejection (n=2). The defects are thought to reflect focally underperfused renal parenchyme or, in normal allografts, an artifact from uneven radioactivity distribution. Four of 10 patients with renal arterial variation showed focally decreased radioactivity and SPECT helped guide funker studies that confirmed the exact cause. Five of 10 patients with acute tubular necrosis or acute rejection showed focally decreased radioactivity, but its relation to the patients' clinical course was not clear. Focally increased radioactivity was observed in 5 allografts with normal function and 1 with double ureter in which local clearance delay was observed. Conclusion: Tc-99m MAG3 SPECT renal scan can detect additional focal abnormalities compared to planar scan. Further study is necessary to elucidate the exact clinical significance of the SPECT findings.

• Korean Journal of Digital Imaging in Medicine
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• v.12 no.1
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• pp.27-31
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• 2010

The purpose of this study was to investigated the usefulness of MR perfusion image comparing with SPECT image. A total of pediatric 30 patients(average age : 7.8) with Moyamoya disease were performed MR Perfusion with 32 channel body coil at 3T from March 01, 2010 to June 10, 2010. The MRI sequences and parameters were as followed : gradient Echo-planar imaging(EPI), TR/TE : 2000ms/50ms, FA : $90^{\circ}$, FOV : $240{\times}240$, Matrix : $128{\times}128$, Thickness : 5mm, Gap : 1.5mm. Images were obtained contrast agent administrated at a rate of 1mL/sec after scan start 10s with a total of slice 1000 images(50 phase/1 slice). It was measured with visual color image and digitize data using MRDx software(IDL version 6.2) and also, it was compared of measurement with values of normal and abnormal ratio to analyze hemodynamic change, and a comparison between perfusion MR with technique using Warm Color at SPECT examination. On MR perfusion examination, the color images from abnormal region to the red collar with rCBV(relative cerebral blood volume) and rCBF(relative cerebral blood flow) caused by increase cerebral blood flow with brain vascular occlusion in surrounding collateral circulation advancement, the blood speed relatively was depicted slowly with blue in MTT(Mean Transit Time) and TTP(Time to Peak) images. The region which was visible abnormally from MR perfusion examination visually were detected as comparison with the same SPECT examination region, would be able to confirm the identical results in MMD(Moyamoya disease)judgments. Hymo-dynamic change in MR perfusion examination produced by increase and delay cerebral blood flow. This change with digitize data and being color imaging makes enable to distinguish between normal and abnormal area. Relatively, MR perfusion examination compared with SPECT examination could bring an excellent image with spatial resolution without radiation expose.

• Journal of KIISE:Software and Applications
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• v.31 no.1
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• pp.54-60
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• 2004

Face recognition is one of the problems to be solved by appearance based matching technique. However, the appearance of face image is very sensitive to variation in illumination. One of the easiest ways for better performance is to collect more training samples acquired under variable lightings but it is not practical in real world. ]:n object recognition, it is desirable to focus on feature extraction or normalization technique rather than focus on classifier. This paper presents a simple approach to normalization of faces subject to directional illumination. This is one of the significant issues that cause error in the face recognition process. The proposed method, ICR(illumination Compensation based on Multiple Linear Regression), is to find the plane that best fits the intensity distribution of the face image using the multiple linear regression, then use this plane to normalize the face image. The advantages of our method are simple and practical. The planar approximation of a face image is mathematically defined by the simple linear model. We provide experimental results to demonstrate the performance of the proposed ICR method on public face databases and our database. The experimental results show a significant improvement of the recognition accuracy.

• Journal of Magnetics
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• v.22 no.1
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• pp.146-149
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• 2017

In this study, we compared the standardized value of each signal intensity, the apparent diffusion coefficient (ADC) that digitizes the diffusion of water molecules, and the signal to noise ratio (SNR) using b value 0 400, 1400 ($s/mm^2$). From March 2013 to December 2013, patients with suspicion of simple compound fracture and metastatic spine cancer were included in the MR readout. We used a 1.5 Tesla Achieva MRI system and a Syn-Spine Coil. Sequence is a DWI SE-EPI sagittal (diffusion weighted imaging spin echo-echo planar imaging sagittal) image with b-factor ($s/mm^2$) 0, 400, 1400 were used. Data analysis showed ROI (Region of Interest) in diseased area with high SI (signal intensity) in diffusion-weighted image b value 0 ($s/mm^2$) Using the MRIcro program, each SI was calculated with images of b-value 0, 400, and 1400 ($s/mm^2$), ADC map was obtained using Metlab Software with each image of b-value, The ADC is obtained by applying the ROI to the same position. The standardized values ($SI_{400}/SI_0$, $SI_{400}/SI_0$) of simple compression fractures were $0.47{\pm}0.04$ and $0.23{\pm}0.03$ and the standardized values ($SI_{400}/SI_0$, $SI_{400}/SI_0$) of the metastatic spine were $0.57{\pm}0.07$ and $0.32{\pm}0.08$ And the standardized values of the two diseases were statistically significant (p < 0.05). The ADC ($mm^2/s$) for b value 400 ($s/mm^2$) and 1400 ($s/mm^2$) of the simple compression fracture disease site were $1.70{\pm}0.16$ and $0.93{\pm}0.28$ and $1.24{\pm}0.21$ and $0.80{\pm}0.15$ for the metastatic spine. The ADC ($mm^2/s$) for b value 400($s/mm^2$) was statistically significant (p < 0.05) but the ADC ($mm^2/s$) for b value 1400 (p > 0.05). In conclusion, multi - b value recognition of signal changes in diffusion - weighted imaging is very important for the diagnosis of various spinal diseases.

• Journal of the Korean Society of Radiology
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• v.15 no.1
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• pp.1-7
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• 2021

In order to acquire an image in a positron emission tomography, it is necessary to draw the position coordinates of the scintillation pixels of the detector module measured at the same time. To this end, in a detector module using a plurality of scintillation pixels and a small number of photosensors, it is necessary to obtain a flood image and divide a region of each scintillation pixel to obtain a position of a scintillation pixel interacting with a gamma ray. Alternatively, when the number of scintillation pixels and the number of photosensors to be used are the same, the position coordinates for the position of the scintillation pixels can be directly acquired as digital signal coordinates. A method of using a plurality of scintillation pixels and a small number of photosensors requires a process of obtaining digital signal coordinates requires a plurality of photosensors and a signal processing system. This complicates the signal processing process and raises the cost. To solve this problem, in this study, we developed a method of obtaining digital signal coordinates without performing the process of separating the planar image and region using a plurality of flash pixels and a small number of optical sensors. This is a method of obtaining the position coordinate values of the flash pixels interacting with the gamma ray as a digital signal through a look-up table created through the signals acquired from each flash pixel using the maximum likelihood function. Simulation was performed using DETECT2000, and verification was performed on the proposed method. As a result, accurate digital signal coordinates could be obtained from all the flash pixels, and if this is applied to the existing system, it is considered that faster image acquisition is possible by simplifying the signal processing process.

• Journal of Korean Society for Geospatial Information Science
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• v.18 no.2
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• pp.35-45
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• 2010

The objective of this study is to verify the positional accuracy by performing the orthometric corrections on the high resolution satellite images and to analyze the band correlation between the high resolution images corrected with orthometric correction. The objectives also included an analysis on the correlation of NDVI. For the orthometric correction of images from KOMPSAT2 and IKONOS, systematic errors were removed in use of RPC data, and non-planar distortions were corrected with GPS surveying data. Also, by preempting the image points at the same positions within ortho images, a comparison was performed on positional accuracies between image points of each image and GPS surveying points. The comparison was also made on the positional accuracies of image points. between the images. For correlation of band and correlation of NDVI, the descriptive statistics of DN values were acquired for respective bands by adding the Quickbird images and Aerial Photographs undergone through orthometric correction at the time of purchase. As result, from a comparison on positional accuracies of Orthoimages from KOMPSAT2 and Ortho Images of IKONOS was made. From the comparison the distance between the image points within each image and GPS surveying points was identified as 3.41m for KOMPSAT2 and as 1.45m for IKONOS, presenting a difference of 1.96m. Whereas, RMSE between image points was identified as 1.88m. The level of correlation was measured by using Quickbird, KOMPSAT2, IKONOS and Aerial Photographs between inter-image bands and NDVI, showing that there were high levels of correlation between Quickbird and IKONOS identified from all bands as well as from NDVI, except a high level of correlation that was identified between the Aerial Photographs and KOMPSAT2 from Band 2. Low levels of correlation were also identified between Quickbird and Aerial Photographs from Band 1. and between KOMPSAT2 and IKONOS from Band 2 and Band 4, whereas, KOMPSAT2 showed low correlations with Aerial Photographs from Band 3. For NDVI, KOMPSAT2 showed low level of correlations with both of QuickBird and IKONOS.

• Investigative Magnetic Resonance Imaging
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• v.3 no.2
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• pp.167-172
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• 1999

Purpose : To evaluate the detection rate of hyperacute intracerebral hemorrhage in echo planar imaging (EPI) and other MR sequences. materials and Methods : Intracerebral hemorrhage was experimentally induced in ten rats. EPI, fast spin-echo (FSE) T2 weighted images, fluid attenuated inversion recovery (FLAIR), spin-echo (SE) T1 weighted images and gradient echo (GE) T1 weight ed images of rat's brains were obtained 2 hours after onset of intracerebral hemorrhage. EPI and FSE T2 images were additionally obtained 30 min and 1 hour after onset of hemorrhage in 3 and 6 rat, repeatedly, For objective visual assessment, discrimination between the lesion and normal brain parenchyma was evaluated on various MR sequences by three radiologists. For quantitative assessment, contrast-to-noise ratio (CNR) was calculated fro hemorrhage-normal brain parenchyma. Statistical analysis was performed usning the Wilcoxon-Ranks test. Results : EPI, FLAIR, and FSE T2 images showed high signal intensity lesions. The lesion discrimination was easier on EPI than on other sequences, and also EPI showed higher signal intensity for the subjective visual assessment. In quantitative evaluation, CNR of the hemorrhagic lesion versus normal brain parenchyma were higher on EPI and FLAIR images (p<0.01). There was no difference in CNR between EPI and FLAIR (p>0.10). On MR images obtained 30 minutes and 1 hour after the onset of intracerebral hemorrhage, the lesion detection was feasible on both EPI and FSE T2 images showing high signal intensity. Conclusion : EPI showed higher detection rate as compared with other MR sequences and could be useful in early detection and evaluation of intracerebral hemorrhage.

• Transactions of the Korean Society of Automotive Engineers
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• v.24 no.2
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• pp.242-254
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• 2016

This paper is the forth investigation on the evaluation methods of flow characteristics in a steady flow bench. In the previous works, it was concluded that the assumption of the solid rotation might cause serious problems and both of the eccentricity and the velocity profile distort the flow characteristics when using the ISM at 1.75B plane. Also particle image velocimetry (PIV) measurement at this position showed that the real velocity profile was far from the assumption of ISM evaluation. In this paper, the planar velocity profiles were measure from 1.75B to 6.00B position by PIV and the characteristics were examined according to the valve angles and lifts for further investigations about the effect of the position on the velocity profile. The results show that $26^{\circ}$ valve angle is always an unique exceptional case in all aspects. If the valve angle is $21^{\circ}$ and below, the planar velocity profiles according to the lift and the position are similar to each other, however, the tangential velocity curves along with the radial direction have common tendencies up to $16^{\circ}$ angle. Also the well arranged swirl behaviors are generally observed at the position above 3.00B and the velocity contour lines come closer to the concentric circle as the valve lift increases. In addition, the gradient of tangential velocity along with the radial direction from the swirl center becomes stable and constant as the position goes downstream. Concurrently the velocity gradient is larger to the eccentric direction of the center. In the meantime the tangential velocity curves along with the radial direction are irregular and various at 1.75B, however, they become regular and reach higher level as the evaluation position goes downstream. At this time the curves of 4.50B are the best fitted to the ideal one. On the other hand in an exceptional case, $26^{\circ}$, the velocity contours are very complicated over 6mm valve lift regardless the position and the gradient increases to the opposite direction of the eccentric center. Also, 6.00B is a best fitting position in the geometrical cylinder center base. With respect to the swirl center, the distribution range of centers for 1.75B is different to that for the other positions and the eccentricities of this plane are larger regardless the valve angle. After 1.75B, there is no certain tendency in the center position change according to the valve angle and lift. Additionally, the eccentricities are not sufficiently small to neglecting the effect on ISM measurement.

• The Korean Journal of Nuclear Medicine
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• v.30 no.3
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• pp.344-350
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• 1996

Purpose : Noninvasive imaging of tumor cell proliferation could be helpful in the evaluation of tumor growth potential and could provide an early assessment of treatment response. Radiolabeled thymidine, uridine and adenosine have been used to evaluate tumor cell proliferation. These nucleoside analogs are incorporated into DNA during proliferation. Iodine-131-Iodomethyluridine, an analog of Iodine-131-Iododeoxyuridine, is also involved in DNA/RNA synthesis. The purpose of this study was to develop Iodine-131-Iodomethylurdine and image tumor proliferation using Iodine-131-Iodomethyluridine. Materials and Methods : Radiosynthesis of Iodine-131-5-Iodo-2'-O-methyluridine (Iodine-131-Iodomethyluridine) was prepared from 10 mg of 2'-O-methyluridine(Sigma chemical Co., St. Louis, Missouri) and 2.1 mCi(SP. 10Ci/mg) of Iodine-131-labeled sodium iodide in $100{\mu}l$ of water using iodogen reaction. Female Fischer 344 rats were inoculated in the thigh area with breast tumor cells(13765 NF, $10^5$ cells/rat S.C.). After 14 days, the Iodine-131-Iodomethyluridine $10{\mu}Ci$ was injected to three groups of rats(3/group). The percent of injected dose per gram of tissue weight was determined at 0.5-hours, 2-hours, 4-hours, and 24-hours respectively. Tumor bearing rats after receiving Iodine-131-Iodomethyluridine($50{\mu}Ci$ IV) were euthanized at 2 hours after injection. Autoradiography was done using freeze-dried $50{\mu}m$ coronal section. After injection of Iodine-131- Iodomethyluridine ($10{\mu}Ci$/rat, IV) in three breast tumor-bearing rats, planar scintigraphy was taken at 45 minutes, 90 minutes and 24 hours. Results : Iodine-131-Iodomethyluridine was conveniently synthesized using iodogen reaction. The biodistribution showed fast blood clearance and the tumor-to-tissue uptake ratios showed that optimal imaging time was at 2 hours postinjection. Autoradiogram and planar scintigram indicated that tumor could be well visualized. Conclusion : The findings suggest that Iodine-131-Iodomethyluridine, a new radio-iodinated nucleoside, has potential use for evaluation of active regions of tumor growth.

• Geophysics and Geophysical Exploration
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• v.11 no.1
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• pp.68-77
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• 2008

We have developed an inversion algorithm for loop-loop electromagnetic (EM) data, based on the localised non-linear or extended Born approximation to the solution of the 2.5D integral equation describing an EM scattering problem. Source and receiver configuration may be horizontal co-planar (HCP) or vertical co-planar (VCP). Both multi-frequency and multi-separation data can be incorporated. Our inversion code runs on a PC platform without heavy computational load. For the sake of stable and high-resolution performance of the inversion, we implemented an algorithm determining an optimum spatially varying Lagrangian multiplier as a function of sensitivity distribution, through parameter resolution matrix and Backus-Gilbert spread function analysis. Considering that the different source-receiver orientation characteristics cause inconsistent sensitivities to the resistivity structure in simultaneous inversion of HCP and VCP data, which affects the stability and resolution of the inversion result, we adapted a weighting scheme based on the variances of misfits between the measured and calculated datasets. The accuracy of the modelling code that we have developed has been proven over the frequency, conductivity, and geometric ranges typically used in a loop-loop EM system through comparison with 2.5D finite-element modelling results. We first applied the inversion to synthetic data, from a model with resistive as well as conductive inhomogeneities embedded in a homogeneous half-space, to validate its performance. Applying the inversion to field data and comparing the result with that of dc resistivity data, we conclude that the newly developed algorithm provides a reasonable image of the subsurface.