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Selecting marker substances of main producing area of Codonopsis lanceolata in Korea using UPLC-QTOF-MS analysis (UPLC-QTOF-MS분석를 이용한 국내산 더덕 주산지의 표지물질 선정)

  • An, Young Min;Jang, Hyun-Jae;Kim, Doo-Young;Baek, Nam-In;Oh, Sei-Ryang;Lee, Dae Young;Ryu, Hyung Won
    • Journal of Applied Biological Chemistry
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    • v.64 no.3
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    • pp.245-251
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    • 2021
  • Codonopsis lanceolata (Deoduk) was grown in East Asia, including Korea, China, Japan, and Russia, and the roots of C. lanceolata have been used as functional foods and traditional medicine to treat symptoms of cough, bronchitis, asthma, tuberculosis, and dyspepsia. The phytochemicals of C. lanceolata have been reported such as phenylpropanoids, polyacetylenes, saponins, and flavonoids that are involved in pharmacological effects such as anti-obesity, anti-inflammation, anti-tumor, anti-oxidant, and anti-microbial activities. Selecting marker substances of the main producing area by MS-based metabolomics analysis is important to ensure the beneficial effect of C. lanceolata without side-effects because differences in cultivated areas of plants were related not only to the safety of medicinal plants but also to changes in chemical composition and biological efficacy. In our present study, ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry combined with multivariate statistical analysis was applied to recognize the main producing area of C. lanceolata in South Korea. As a result of Principal Component Analysis and loading plot analysis of three groups, Inje (Kangwon-do), Hoengseong (Kangwon-do), and Muju (Jeonlabuk-do), several secondary metabolites of C. lanceolata including tangshenoside I, lancemaside A, and lancemaside G, were suggested as potential marker substances to distinguish the place of main producing area of C. lanceolata.

Scientific Analysis and Conservation of Waterlogged Woods Excavated from Suyoeng-ri Site, Hwaseong, Korea (화성 수영리 유적 출토 수침목제유물의 과학적 분석 및 보존처리)

  • Lee, Kwang-Hee;Oh, Jeong-Eun;Kim, Soo-Chul
    • Journal of Conservation Science
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    • v.37 no.5
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    • pp.579-589
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    • 2021
  • Five waterlogged wood artefacts were excavated from Suyeong-ri site in Hwaseong, South Korea. The aim of the present study was to identify the species and estimate the date of manufacture and the manufacturing method of these artefacts. The study also aimed to conserve the original shapes of waterlogged wood artefacts by using the vacuum freeze drying method. The two large waterlogged woods were identified as Ulmus spp. and Morus spp., whereas one of the three small waterlogged woods was identified as Abies spp. and the other two as hard pine. Radiocarbon dating using wiggle match dated the manufacturing of these wooden artefacts between BCE 8520-8490 or BCE 8470-8290 in the Neolithic age, and a similar period was also confirmed for seed excavated from a place close to the location where the waterlogged wood artefacts were excavated. The surface of waterlogged wood artefacts had several traces of manufacturing processes - traces of tearing and chopping - were observed. Based on these observations, it was confirmed that stone adz was used to make these wooden artefacts. Thereafter, the waterlogged wood samples were conserved by immersing them into PEG#4,000 of concentration in water from 10% to 40% at room temperature(15~25℃) and subjecting them to vacuum freeze drying. However, the internal moisture was not completely removed in some thick parts of waterlogged woods by applying the general schedule such as raising the shelf temperature as the surface temperature rises. Therefore, additional study is required using the schedule-method for vacuum freeze drying of large waterlogged wood.

Full mouth rehabilitation of edentulous patient with fixed implant prosthesis (고정성 임플란트 보철물을 이용한 완전 무치악 환자의 구강회복 증례)

  • Shi, Hee-Hyun;Kim, Jong-Jin;Baik, Jin;Cha, Hyun-Suk;Lee, Joo-Hee
    • Journal of Dental Rehabilitation and Applied Science
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    • v.37 no.3
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    • pp.147-156
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    • 2021
  • There are various treatment options such as conventional complete denture, hybrid prosthesis and implant-supported fixed prosthesis for fully edentulous patients. In case of implant-supported fixed prosthesis, compared to removable prosthesis, it is difficult to place the implant in the correct position considering the anatomical contours of the final prosthesis. In this case, a full mouth rehabilitation with implant-supported fixed prosthesis was performed for a patient who required extraction of all remaining teeth due to dental caries and chronic periodontitis. In the implant placement stage, the implant was placed in the desired position using a surgical guide fabricated considering the anatomical contours of the final prosthesis, and the function and esthetics were evaluated through correction and re-fabrication of the fixed provisional restoration. A final restoration of porcelain fused to gold prosthesis was delivered to the patient based on the provisional restoration. To cope with complications such as loosening of screws and fracture of porcelain, a screw-retained type prosthesis was fabricated for the posterior part and a screw-cement-retained type prosthesis for the anterior part. As a result, the patient showed an improved prognosis in terms of functional and esthetics after the final prosthesis was delivered.

Examining the Strategic Priorities for Smart City Project with Analytic Hierarchy Process Based on a Survey of Potential Residents (AHP를 활용한 스마트시티 사업의 전략적 우선순위 분석: 잠재적 주민을 대상으로)

  • Kang, Haeun;Kim, Seung-Chul;Lee, Taewon;Chang, Mikyung;Lee, Ayeon
    • Journal of Digital Convergence
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    • v.19 no.12
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    • pp.243-253
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    • 2021
  • In this study, AHP analysis was conducted on potential residents who are willing or likely to live in a smart city. The purpose is to identify priorities for strategic objectives. In order to establish a hierarchical structure for the vision, core values, and strategic goals of the smart city business, we researched domestic and overseas smart city-related academic papers and research reports, business plans, and institutional websites. After reviewing professors, researchers, experts, and focus groups, 4 2nd tier and 12 3rd tier properties were finally selected and the hierarchical structure was confirmed. As a result of AHP analysis, it was found that residents place the highest importance on quality of life in smart city projects. As a result of the analysis of the lower-level factors, it was found that safety was the most important. The priorities were analyzed in the order of living convenience, eco-friendliness, and social inequality resolution. It is expected that the results of this analysis will be able to suggest strategies to be established when promoting smart city projects in the future.

The Legitimacy of Telemedicine and its Limit (원격의료의 허용 여부와 그 한계)

  • Hyu, Doo-youn
    • The Korean Society of Law and Medicine
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    • v.21 no.3
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    • pp.3-33
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    • 2020
  • Telemedicine can be defined as "medical activities performed remotely by medical personnel using information and communication technology." So far, many scholars in Korea have understood that only telemedicine between medical personnel is allowed and telemedicine between medical personnel and patients is prohibited based on Article 34 of Medical Service Act. However, Article 34 is only a restriction on the performing place of medical profession, not a prohibition on telemedicine itself. And, there are no regulations prohibiting telemedicine under the korean medical law. So, it is difficult to say that telemedicine is generally prohibited under the korean medical law, apart from the health insurance medical treatment benefit standards. However, there is controversy in interpretation regarding the meaning of "direct diagnosis" in Articles 17 and 17-2 of Medical Service Act. The Constitutional Court of Korea interpreted this as "face-to-face diagnosis", while the Supreme Court of Korea interpreted it as "self diagnosis". In light of the dictionary meaning of 'direct' and the interpretation of related medical law regulations, I think the Supreme Court's interpretation is valid. Although "direct diagnosis" does not mean "face-to-face diagnosis", the concept of "diagnosis" implies "principle of face-to-face diagnosis". In addition, "non-face-to-face diagnosis" are only allowed to supplement "face-to-face diagnosis", so the problems caused by "non-face-to-face diagnosis" can be fully overcome. In the end, the limit of telemedicine is how faithful the diagnosis was.

A Study on the Two Big Theories of Music Culture in China's Ancient Times (중국전통시기 양대(兩大) 음악문화 고찰)

  • Lee, Tae Hyoung
    • Cross-Cultural Studies
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    • v.43
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    • pp.355-376
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    • 2016
  • This study looks into the relationship between Chinese philosophy, with a focus on Confucianism and Taoism, and music. Kong zi's Confucius supported, 'Enjoyment without being licentious and grief without being hurtfully excessive', and 'hatred of the music of Zheng'. These ideas do not emphasize the function of music as an expression of emotions, feelings, or desires, and are instead conclusions based on Confucian ideals such as harmony between classes and the spread of benevolent government. Music must coincide with Justice. The hatred of the music of Zheng was a conclusion founded on the idea of a place for Justice in music. Zhuangzi is the source of the spirit of Chinese art; specifically, Zhuangzi's idea of music in relation to its influence on East Asian history of art is extremely influential. In fact, the concept of yuelun is considered the most original and important concept in the history of the East Asian philosophy of art. The most distinctive features of Zhuangzi's theory of music can be summarized as follows. He attempts to liberate music from the restrictions of form and to let music express authentic human feelings and emotions. He also argues that music should not be subjected to politics, as he thinks that the creative mind of an artist can exist only when music is freed from political influence. Confucianism takes a humanistic perspective, while Taoism takes a more naturalistic one. In sum, Confucianism gives weight to the logical and ethical aspects of music, while Taoism emphasizes the intuitional and naturalistic ones.

A Study on Development of Mobile LNG Yard Tractor Refueling Standards (이동식 LNG 야드트랙터 충전 기준 개발 연구)

  • Ryou, Young-don;Yu, Chul-hee;Koo, Bon-deuk;Lee, Dong-won
    • Journal of the Korean Institute of Gas
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    • v.22 no.6
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    • pp.59-64
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    • 2018
  • As part of measures to reduce fine dust, the government is promoting a project to convert the fuel of Yard Tractors(YT, tractors operated at ports), from diesel to LNG (Liquefied Natural Gas). While a port having a small number of yard tractors, it is not proper to construct a stationary LNG fueling station and supply LNG to YT due to a problem of BOG (Boil off gas) generation. Therefore, it is necessary to make a regulation and a standard on mobile LNG YT refueling station installation and inspection as an alternative. In this study, we have investigated domestic and foreign mobile LNG refueling cases and refueling standards, including the USA and Europe. In addition, we have suggested the risk reduction method according to the cause after investigation of the cause of LNG accidents. And last, based on the proposed risk reduction measures, we have proposed an amendment to the Regulation of the Urban Gas Business Law in Korea. The proposed mobile LNG YT refueling amendment of the Regulation includes ; maintenance of the safety distance from the protection facility, installation of an interlock device to prevent refueling in places other than the authorized place, installation of the identification system through biometrics, separation of the tank lorry and tow vehicle before refueling, checking the wheel fixed status of tank lorry before refueling, construction of the impounding area, safety measures before, during and after refueling, etc. The safety standards proposed in this study could be used as a reference in establishing standards for mobile LNG vehicle refueling in the near future.

Socioeconomic and Sociodemographic Factors related to Allergic Diseases in Korean adolescents based on the 14th Korean Youth Risk Behavior Survey (청소년의 알레르기성 질환과 관련된 사회경제적 및 사회인구학적 요인: 제14차 한국청소년건강행태조사를 기반으로)

  • Kim, Bong Hee;Kim, Hae Ran
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.8
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    • pp.494-502
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    • 2019
  • Various international reports have shown strong proof that socioeconomic and sociodemographic variables are correlated with allergic diseases, yet little is known about how these variables affect Korean adolescents. This study was conducted to identify the socioeconomic and sociodemographic risk factors for allergic diseases of Korean adolescents, and to provide information for preventing and managing such conditions. Data from the 2018 Korean Youth Risk Behavior Survey (KYRBS) of 60,040 adolescents was used for this study. An anonymously administered online survey was conducted to collect information on the dependent variables. The independent variables were asthma, allergic rhinitis and atopic dermatitis. Multivariate logistic regression analysis was performed to analyze the correlations between the dependent variables and the independent variables. Low economic status, living with mother, high education level of parents, high school record, obesity, drinking and smoking were the risk factors for asthma. Low economic status, the place of residence, living with mother, high education level of the parents, gender, high school record, obesity, drinking and smoking were the risk factors for allergic rhinitis. Low economic status, living with mother, high education level of parents, genderhigh school record, obesity and drinking were the risk factors for atopic dermatitis. We found that low socioeconomic status and unhealthy behavior were the risk factor for allergic diseases of Korean adolescents. Balanced economic growth in the community and controlling unhealthy behavior can help reduce the prevalence of allergic diseases.

A Study on the Management Improvement of an Academic Library Using Customer Relationship Management (CRM 기법을 이용한 대학도서관 경영개선에 관한 연구)

  • Park, Il-Jong;Yoo, Kyeong-Jong
    • Journal of the Korean Society for information Management
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    • v.36 no.2
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    • pp.31-56
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    • 2019
  • The user satisfaction and needs of an academic library were caught through a questionnaire survey in this study. The aim of this study is to draw up the CRM based plan for meeting user needs on the study. The users' demographic information, library resources & their use, homepage, services, and facilities/environment of the library were categorized in the questionnaire and analyzed for this study. The major conclusions of this study are: (1) The library resources use was the highest, and its facilities/environment was the lowest in the user satisfaction study. It also revealed that there are much necessities for the quick acquisition and dissemination of the requested material to the library users, and for the inter-library loan (ILL) services among campuses for the subscription books in the library resources use study, too; (2) There are a lot of necessities for the improvement of OPAC retrieval and the subscription books system, and menu rearrangement in the library homepage; (3) There are a lot of necessities for the plans of more frequent library event, more detailed event guidance, and more reinforcement of public relations such as SMS, push services of SDI etc. in the library user services; and (4) There are a lot of necessities for the improved policies to the complaints of library users such as the lack of common study place and lockers, air conditioning and heating problem, complaints about facilities management of restroom (lack of toilet paper), library accessibility on campus, unauthorized user management etc. in the facilities/environment of the library.

Study on the Eating Out Behavior of Middle School Students (중학생의 외식 실태에 대한 연구 - 2016년 청소년 식품소비행태조사 -)

  • Na, Ye-Seul;Jeon, Eun-Raye;Jung, Lan-Hee
    • Journal of the Korean Society of Food Culture
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    • v.34 no.3
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    • pp.284-295
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    • 2019
  • This study examined the actual condition of middle school students' dining out based on the data of the 2016 youth food behavior inquiry data of the Korea Rural Economic Institute. The eating out behavior of 278 middle school students' according to gender, average eating-out cost per person, average monthly eating out cost per person, weekly frequency of breakfast, and dietary information source were calculated into a chi-square value by cross analysis. The main results of this study are as follows. First, in middle school students' eating-out status, most students answered 'eating out', and the highest frequency of eating out was 1~3 times a week. The reason for eating out was 'to enjoy delicious food', and 'costly price' was the most common reason for not eating out. Food taste was the most common standard for selecting eating out, and a restaurant was the most common place to eat out. The main restaurant was the 'snack bar (kimbap specialized store)'. Second, there was no significant difference in all items of eating-out status according to the gender. A significant difference in eating out frequency was observed according to average eating-out cost per once (p< .001), standard for selecting eating out (p< .001), main eating out places (p< .001), and main restaurants (p< .01). There was a significant difference in the frequency of eating out (p< .001) in the eating-out status according to average eating out cost per month. Third, the eating-out status according to the breakfast frequency of middle school students had a significant difference in the reason for eating out (p< .001). The eating-out status according to the dietary information source of middle school students had a significant difference in eating out or not (p< .05) and the frequency of eating out (p< .05). These results highlight the importance of school diet education so that middle school students can achieve healthy eating habits and plan to increase their interest and utilization of school dietary education.