• Title/Summary/Keyword: Piperaceae

Search Result 14, Processing Time 0.022 seconds

Piperine, a Primary Component of Black Pepper, inhibits Prostagladins Generation by Suppression of COX Activity on Arachidonic Acid Metabolism in LPS-Stimulated RAW264.7 Cells

  • Son, Dong-Ju;Park, Byeoung-Soo;Lee, Sung-Eun;Kitatani, Kazuyuki;Park, Young-Hyun
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.258.1-258.1
    • /
    • 2002
  • Piperine (piperinoyl-piperidine) is a nitrogenous pungent substance contained in black pepper. the well know spice obtained from Piper nigrum L. (Piperaceae). Pharmacological studies have shown that piperine reduces inflammation and pain. possesses anticonvulsant and antiulcer activity. protects the liver and has deleterious effects on testis function. Prostaglandins(PGs) are a family of intercellular and intracellular messengers derived from arachidonic acid(AA) by phospholipase(PL) and cyclooxygenase(COX). (omitted)

  • PDF

Selection of Korean Native Plants as Outdoor Pot Plants (실외 화분용 자생식물 선발)

  • Sohn, Kwanhwa;Kim, Hoon Sik
    • FLOWER RESEARCH JOURNAL
    • /
    • v.18 no.2
    • /
    • pp.98-109
    • /
    • 2010
  • 78 Korean native plants, which have not been used in general, were selected to be used as outdoor pot plants for three seasons, from spring to autumn. Plants, which were explored in about 30 places of Korea from 2007 to 2009, were transplanted to or sown in white plastic general pots ($27.5cm({\Phi}){\times}27.5cm(H)$) and hanging pots($28cm({\Phi}){\times}13cm(H)$) and grown in the garden of 36''56' latitude(N) and 127''09' longitude(E). 38 species(13 families and 29 genus) were suitable for outdoor general pots, and 46 species(28 families and 43 genus) for outdoor hanging pots. Among 38 plants for outdoor general pots, the principal species, which were easy to grow and have not been used in general, were 16 species, Metaplexis japonica in Asclepiadaceae, Phyteuma japonicum in Campanulaceae, Artemisia capillaris, Artemisia princeps, and Artemisia selengensis in Compositae, Carex humilis in Cyperaceae, Pennisetum alopecuroides, and Setaria viridis in Gramineae, Agastache rugosa, Glechoma hederacea, Elsholtzia splendens, Isodon inflexus, and Mosla punctulata in Labiatae, Vicia villosa in Leguminosae, Piper kadzura in Piperaceae, and Rosa multiflora var. multiflora in Rosaceae. Among 46 plants for outdoor hanging pots, the principal species, which were easy to grow and have not been used in general, were 17 species, Metaplexis japonica in Asclepiadaceae, Ixeris stonlonifera in Compositae, Calystegia japonica and Quamoclit angulata in Convolvulaceae, Dioscorea batatas in Dioscoreaceae, Glechoma hederacea and Thymus quinquecostatus in Labiatae, Trifolium lupinaster for. alpinus and Vicia villosa in Leguminosae, Menispermum dauricum in Menispermaceae, Piper kadzura in Piperaceae, Clematis mandshurica for. lancifolia in Ranunculoideae, Rosa multiflora var. multiflora and Potentilla fragarioides var. major in Rosaceae, Paederia scandens and Rubia akane in Rubiaceae, and Parthenocissus tricuspidata in Vitaceae.

Antignawing Activity of Plant Extracts against Mice (식물체 추출물의 생쥐에 대한 갉기억제활성)

  • Yun, Eun-Jun;Lee, Sung-Baek;Lee, Hee-Kwon;Lee, Hoi-Seon;Ahn, Young-Joon
    • Applied Biological Chemistry
    • /
    • v.41 no.1
    • /
    • pp.95-98
    • /
    • 1998
  • Methanol extracts of 54 plant species in 32 families were tested for their antignawing activities against mice by wire-dipping method. The activity varied with plant species. Potent antignawing activity was observed in extracts from roots of Aucklandia lappa (Compositae), barks of Cinnamomum cassia (Lauraceae), fruits of Illicium verum (Magnoliaeceae), fruits of Piper nigrum (Piperaceae), rhizomes of Rheum officinale (Polygonaceae), and leaves of Pinus densiflora (Pinaceae). As naturally occurring rodent repellents, these plant-derived materials could be useful as a preventive agent against various kinds of damage caused by rodents.

  • PDF

Induction of Apoptosis and Inhibition of Growth in Human Gastric Cancer by Piperine (Piperine에 의한 위암세포 AGS 증식 억제와 Apoptosis 유도)

  • Shin, Seong-Ah;Lee, Hae-Nim;Choo, Gang-Sik;Kim, So-Jung;Kim, Hyeong-Jin;Park, Young-Seok;Park, Byung-Kwon;Kim, Byeong-Soo;Kim, Sang-Ki;Lee, Hu-Jang;Jung, Ji-Youn
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.45 no.11
    • /
    • pp.1589-1594
    • /
    • 2016
  • Piperine [(E,E)-5-(3,4-methtylenedioxyphenyl)-2,4-pentadienolypiperidide] is a principal of Piperaceae, including Piper nigrum L. and Piper longum Linn., which has been used as a spice and traditional medicine. In this study, we investigated whether or not piperine has anti-cancer effects on AGS human gastric cancer cells. The results demonstrated that piperine not only inhibited proliferation using MTT assay but also induced apoptotic bodies using DAPI assay in a dose-dependent manner in response to piperine. Expression levels of p53, Bax (pro-apoptotic), cleaved caspase-9, and cleaved-PARP increased, whereas expression levels of Bcl-2, XIAP (anti-apoptotic), and Akt decreased in a dose-dependent manner compared with the control by western blotting analysis. To identify the connection between phospo-Akt and Bcl-2 family in response to piperine, LY249002 (Akt inhibitor) was treated with piperine ($150{\mu}M$). The results were shown that expression of phospo-Akt was reduced whereas expression of Bax and cleaved-PARP increased in a dose-dependent manner. These results indicate that piperine induced apoptosis in AGS cells and may serve as a chemopreventive or therapeutic agent for human gastric cancer.