• Title/Summary/Keyword: Pim-1

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Suggestion of the defect score and condition grading protocol about sewer pipe (하수관로 결함 점수 및 상태 등급 판정 방법 제안)

  • Kim, Jungruyl;Lee, Jaehyun;Oh, Jeill
    • Journal of Korean Society of Water and Wastewater
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    • v.31 no.1
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    • pp.21-28
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    • 2017
  • This study was performed to propose the sewer defect scoring, and grading protocols for sewer condition assessment. For this, sewer defect scoring methods were comparatively analyzed and reviewed for four international condition assessment protocols, which are established based on WRc manual. As a result, we proposed a new protocol for sewer condition assessment, in which characteristics of sewer pipes are considered by segment. In reference to the PIM-3, the extent of ground subsidence was adopted to be of importance, and renewal scores increased in accordance with weighting of defects causing structural backfill materials. Also, defect grades of 'Hole' were extended to 5 levels of the grading, and 'Surface Damage' was excluded in defect assessment. The addition of 'Buckling' resulted in reduction of weights in 'Surface Damage' and 'Lining Defects'.

A Study on the Seed Characteristics and Germination Percent of Several Native Herb Species (자생 초본류 몇 종의 종자특성과 발아율에 대한 연구)

  • 김갑태
    • Korean Journal of Environment and Ecology
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    • v.18 no.1
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    • pp.1-6
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    • 2004
  • Seed characteristics-weight, seed length and width, pure seed percentage are measured on 15 native herb species, and seeds of six native herb species were tested on the seedbed in the forest with autumn seeding. Seeds of 13 species including Aster scaber were very small; seed length is less than 7mm and seed width is less than 3mm pure seed percentages of 10 native herb speciesin-cluding Ligularia fischeriwere were much lower than 5%. Germination percent of five native herb species were significantly different among the growing sites. The mean germination percent was highest 47.00% for Angelica gigas, 38.25% for Ligularia fischeri, 30.88% for PimPinella brachycarpa, 15.75% for Aralia continetalis, 10.00% for Cirsium setidens, and the lowest 9.32% for Aster scaber.

A Business Model of Small and Medium-Sized Enterprises: A Case Study of the Textile and Clothing Industry in Thailand

  • SAWATENARAKUL, Natha;ROOPSING, Taweesak
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.7
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    • pp.151-160
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    • 2021
  • The purposes of this research were: 1) to analyze the confirmatory factors with the business operational model of entrepreneurs of small and medium enterprises (SMEs) in the textile and clothing industry, and 2) to verify the congruence of the model with the operational ways of the entrepreneurs of SMEs in the textile and clothing industry. The sample consisted of 500 small and medium enterprise entrepreneurs in the textile and clothing industry. This study was quantitative research and the instrument used to collect the data was a questionnaire. The data was analyzed using 1st order and 2nd order of confirmatory analysis (CFA). The findings of this research revealed that the model of SMEs in the textile and clothing industry was overall at a high level. Four main factors were used for the model of SMEs in the textile and clothing industry by their importance in descending order as follows: marketing mix (MM), collaboration network (CN), production inventory management (PIM), and creativity (CT). The results of verification of model congruence revealed the model of SMEs in the textile and clothing industry was fit and in accordance with the empirical data.

A Study on The Preference Analysis of Personal Information Security Certification Systems: Focused on SMEs and SBs (개인정보보호 인증제도 선호도 분석에 관한 연구: 중소기업 및 소상공인을 중심으로)

  • Park, Kyeong-Tae;Kim, Sehun
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.24 no.5
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    • pp.911-918
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    • 2014
  • Over the past few years, security breaches have been consistently reported around the world. Especially, people's personal information are at risk of being breached as the firms gather and utilize the information for their marketing purposes. As an effort to revamp their data infrastructures, companies have rebuilt their system that almost every data, including the personal information, are stored within the digital database. However, this migration provides easier access to the database but it has also increased the system vulnerability. As the data can be easily exposed to the unauthorized personnel both intentionally and unintentionally, it is necessary for companies to establish a set of security protocol and operate the personal information protection system. There are two major certified security system in South Korea; PIMS from KISA and PIPL from NIA. This paper analyzes the preferences of SMEs and small business using conjoint attributes of PIMS and PIPL. The study shows that the business owners take post certification rewards as the most important factor. It also shows that the attributes that have the highest utility rates are the following; 1) KISA certification, 2) 79 points of protection counter measurements, 3) 28 items of life cycle, 3) 50 percent discount on certification fee, and 4) Reduced amount of fine for personal information leakage incident.

Design and Implementation of Dynamic Group Key Management Protocol for Multicast Information Security (전자상거래를 위한 멀티캐스트 그를 키 관리 프로토콜 설계 및 구현)

  • 홍종준;김태우
    • Convergence Security Journal
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    • v.2 no.1
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    • pp.99-107
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    • 2002
  • This paper proposes a group key management protocol for a secure of all the multicast user in PIM-SM multicast group communication under electronic commerce. Each subgroup manager gives a secure key to it's own transmitter and the transmitter compress the data with it's own secure key from the subgroup manager. Before the transmitter send the data to receiver, the transmitter prepares to encrypt a user's service by sending a encryption key to the receiver though the secure channel, after checking the user's validity through the secure channel. As the transmitter sending a data after then, the architecture is designed that the receiver will decode the received data with the transmitter's group key. Therefore, transmission time is shortened because there is no need to data translation by the group key on data sending and the data transmition is possible without new key distribution at path change to shortest path of the router characteristic.

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A study on Optimization of Using QoS and Ensuring the Security in IPv6 Multicast Network (IPv6 Multicast 네트워크에서 QoS 적용과 Security보장을 위한 최적화 연구)

  • Kim, Young-Rae;Lee, Hyo-Beom;Min, Sung-Gi
    • Proceedings of the Korea Information Processing Society Conference
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    • 2008.05a
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    • pp.913-916
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    • 2008
  • TPS(Triple Play Service)를 통한 IP-TV,인터넷, 전화 등이 통합되는 추세에서, IPv6 상용네트워크가 수 년 안에 구축될 필연성을 공감하고 있다. 그러나 [1] 현재 IP-TV 서비스에서 Delay, Jitter,전송장애등 QoS에 대한 사용자 불만이 계속 발생하고 있다. 또한 현재 서비스중지 (DoS : Denial of Service)를 유발하는 [2] 인터넷 침해 사고가 월 평균 2157건 이상 발생하는 등, Security Issue의 증가 문제가 지속 되고 있다. IPv4/IPv6 듀얼 스택 멀티 캐스트 네트워크를 구현하여, 라우팅, 멀티캐스트(PIM-SM), QoS, Security 이슈에 대한, 최적의 방안을 도출하여, 라우팅 구현시 IPv6 라우팅 프로토클 간에 재분배(Redistribution) 장애 해결책, IPv6 특성에 따른 멀티캐스트 그룹주소 지정시의 장애대책을 제시하였고, QoS 에서는 기존의 QoS 정책의 문제점과 IPv6의 고유한 패킷 구조의 장점을 활용한 Adaptive QoS 방법을 제시하고, IPv6 멀티캐스트 서비스 중지 공격 유형을 정의하여, 최적화된 IPv6 멀티캐스트 구성 모델을 제시 하였다. 결론적으로 구현된 시스템에서 IPv6 패킷 분석을 통해서 최적화된 경로 통신 및 차별화된 IPv6 패킷의 QoS 방안을 제시하였으며, 서비스 중지공격을 대응하는 Security 보장성을 갖고 있음을 검증하여, 향후 상용화된 IPv4/IPv6 네트워크 구현을 위한 최적화 방안을 제시 하였다.

Microarray and Quantitative PCR Analysis of Gene Expression Profiles in Response to Treatment with Tomato Leaf Extract in MCF-7 Breast Cancer Cells

  • Amid, Azura;Chik, Wan Dalila Wan;Jamal, Parveen;Hashim, Yumi Zuhanis Has-Yun
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6319-6325
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    • 2012
  • We previously found cytotoxic effects of tomato leaf extract (TLE) on the MCF-7 breast cancer cell line. The aim of this study was to ascertain the molecular mechanisms associated with the usage of TLE as an anticancer agent by microarray analysis using mRNA from MCF-7 breast cancer cells after treatment with TLE for 1 hr and 48 hrs. Approximately 991 genes out of the 30,000 genes in the human genome were significantly (p<0.05) changed after the treatment. Within this gene set, 88 were significantly changed between the TLE treated cells and the untreated MCF-7 cells (control cells) with a cut-off fold change >2.00. In order to focus on genes that were involved in cancer cell growth, only twenty-nine genes were selected, either down-regulated or up-regulated after treatment with TLE. Microarray assay results were confirmed by analyzing 10 of the most up and down regulated genes related to cancer cells progression using real-time PCR. Treatment with TLE induced significant up-regulation in the expression of the CRYAB, PIM1, BTG1, CYR61, HIF1-${\alpha}$ and CEBP-${\beta}$ genes after 1 hr and 48 hrs, whereas the TXNIP and THBS1 genes were up-regulated after 1 hr of treatment but down-regulated after 48 hrs. In addition both the HMG1L1 and HIST2H3D genes were down-regulated after 1 hr and 48 hrs of treatment. These results demonstrate the potent activity of TLE as an anticancer agent.

DNA Microarray Analysis of Methylprednisolone Inducible Genes in the PC12 Cells

  • Choi, Woo-Jin;Choi, Seung-Won;Kim, Seon-Hwan;Kim, Youn;Kwon, O-Yu
    • Biomedical Science Letters
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    • v.15 no.3
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    • pp.261-263
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    • 2009
  • Methylprednisolone is a synthetic glucocorticoid which is usually taken intravenously for many neurosurgical diseases which cause edema including brain tumor, and trauma including spinal cord injury. Methylprednisolone reduces swelling and decreases the body's immune response. It is also used to treat many immune and allergic disorders, such as arthritis, lupus, psoriasis, asthma, ulcerative colitis, and Crohn's disease. To identify genes expressed during methylprednisolone treatment against neurons of rats (PC12 cells), DNA microarray method was used. We have isolated 2 gene groups (up- or down-regulated genes) which are methylprednisolone differentially expressed in neurons. Lipocalin 3 is the gene most significantly increased among 772 up-regulated genes (more than 2 fold over-expression) and Aristaless 3 is the gene most dramatically decreased among 959 down-regulated genes (more than 2 fold down-expression). The gene increased expression of Fgb, Thbd, Cfi, F3, Kngl, Serpinel, C3, Tnfrsf4 and Il8rb are involved stress-response gene, and Nfkbia, Casp7, Pik3rl, I11b, Unc5a, Tgfb2, Kitl and Fgf15 are strongly associated with development. Cell cycle associated genes (Mcm6, Ccnb2, Plk1, Ccnd1, E2f1, Cdc2a, Tgfa, Dusp6, Id3) and cell proliferation associated genes (Ccl2, Tnfsf13, Csf2, Kit, Pim1, Nr3c1, Chrm4, Fosl1, Spp1) are down-regulated more than 2 times by methylprednisolone treatment. Among the genes described above, 4 up-regulated genes are confirmed those expression by RT-PCR. We found that methylprednisolone is related to expression of many genes associated with stress response, development, cell cycle, and cell proliferation by DNA microarray analysis. However, We think further experimental molecular studies will be needed to figure out the exact biological function of various genes described above and the physiological change of neuronal cells by methylprednisolone. The resulting data will give the one of the good clues for understanding of methylprednisolone under molecular level in the neurons.

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Production of TNF-${\alpha}$ and IL-6 in Macrophages by Mycobacterial Protein Antigens (결핵균 단백항원 자극에 의한 대식세포의 TNF-${\alpha}$ 및 IL-6 생성과 ERK 활성화)

  • Ahn, Hae-Jeong;Cho, Sang-Nae;Paik, Tae-Hyun;Lee, Jung-Lim;Choi, In-Hong
    • IMMUNE NETWORK
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    • v.7 no.1
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    • pp.26-30
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    • 2007
  • Background: Mycobacterial antigens released as PIM, LM, LAM, lipoproteins and other cellular factors may contribute to macrophage and dendritic cell activation through pattern recognition receptors such as TLRs. In this study, we assessed cytokine production and ERK activation with stimulation of several major mycobacterial antigens. Methods: Purified mycobacterial antigens (10, 22, 30, 38kDa) and recombinant antigens (6, 16, 19, 38kDa, Ag85A antigen) were studied. The production of cytokines (TNF-${\alpha}$, IL-12, IL-6) was measured by ELISA. The ERK activation was detected by western blotting. The expression of TLR2 or TLR4 was measured by flow cytometry. Results: Among purified antigens only 30kDa antigen induced production of IL-6 or TNF-${\alpha}$ in THP-1 macrophage cells. When THP-1 macrophage cells were treated with 30kDa antigen, phosphorylation of ERK was detected. ERK activation also occurred in TLR2 transfectant HEK293 cells with 30kDa antigen stimulation. Conclusion: 30kDa antigen is one of the major mycobacterial antigens inducing cytokine production and MAP kinases phosphorylation in macrophages.

Internet Multicast Routing Protocol Model using MPLS Networks (MPLS망을 이용한 인터넷 멀티캐스트 라우팅 프로토콜 모델)

  • Kim, Young-Jun
    • The KIPS Transactions:PartC
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    • v.10C no.1
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    • pp.77-86
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    • 2003
  • This paper describes the new method for Internet multicast routing protocols using MPLS (Multiprotocol Label Switching) networks. Internet multicast routing protocols are divided into three categories in terms if tree types and tree characteristics : a shortest path tree a shared tree and hybrid tree types. MPLS should support various multicast mechanisms because of extremely different IP multicast architectures, such as uni-/bi-directional link, Flooding/prune tree maintenance mechanism. the existence of different tree types with the same group, etc. There are so many problems over MPLS multicast that the solutions can't be easily figured out. In this Paper, we make a few assumptions on which the solutions of IP multicast routing protocols over MPLS networks are given. A broadcasting label is defined for the shortest path tree types. Cell interleaving problems of the shared tree types is solved by using block-based transmission mechanism. Finally, the existing hybrid-type multicast routing protocol is reasonably modified Shortest Path tree type to support MPLS multicast. It has been shown that these modifications give better performance (transmission delay) than the orignal method.