• Title/Summary/Keyword: Pilot trial

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A Pilot Study of the Effectiveness of a Session of Group Cognitive Behavioral Therapy for Patients with Panic Disorder (공황장애에서 1회기 집단인지행동치료의 효능 ; 예비 연구)

  • Jahng, Eun-Jin;Jeong, Young-Eun;Seo, Ho-Jun;Chae, Jeong-Ho
    • Anxiety and mood
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    • v.5 no.1
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    • pp.36-41
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    • 2009
  • Objectives : The purpose of this pilot study was to investigate the potential clinical benefits a single group session of cognitive behavioral therapy in the treatment of patients with panic disorder. Methods : The study participants were 18 patients (14 males, 4 females; mean age=38.9 years), all of whom were assessed as meeting the DSM-IV-TR criteria for panic disorder. All participants attended one two-hour session of structured group cognitive behavioral therapy (CBT). Clinical symptoms was assessed before and eight weeks after the single therapy session using the Panic Disorder Severity Scale (PDSS). Results : Eight weeks after a single session of group CBT significant improvements were found in panic attack frequency, distress during panic attacks, severity of anticipatory anxiety, agoraphobic fear/avoidance, panic-related sensation fear/avoidance, impairment in work functioning, impairment in social functioning. Conclusions : One session of group CBT appears to be an effective treatment of panic disorder by reducing the severity of all symptoms assessed on the PDSS. An attempt should be made to replicate the findings of this pilot study in a larger and controlled, comparative clinical trial.

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The Effects of Gabapentin in Treatment of Burning Mouth Syndrome: Retrospective Pilot Study

  • Heo, Jun-Young;Ok, Soo-Min;Jeong, Sung-Hee;Kim, Kyung-Hee;Ahn, Yong-Woo
    • Journal of Oral Medicine and Pain
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    • v.39 no.3
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    • pp.96-99
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    • 2014
  • Purpose: The objective of this retrospective pilot study was to evaluate the effectiveness of Gabapentin in patients with primary burning mouth syndrome (BMS). Methods: Ten subjects were diagnosed with primary BMS (8 women and 2 men). The mean age was 60.1 years. They had clinical examination to exclude local factors such as the presence of Candida species, xerostomia, lichen planus, etc. They also underwent hematological examination to exclude secondary BMS due to systemic disorders. Pain was assessed by patients on an 11-point numerical rating score system (0 to 10). Gabapentin was administered at a starting dose of 300 mg/day, slowly titrated up to maximum of 1,800 mg/day. All patients were treated for 4 weeks. Results: One half of the patients (n=5) obtained reduction in pain over the treatment period. Four patients reported no reduction in pain symptoms. One patient reported that symptoms were worsening. The average pain score before the treatment was 6.3 and after the treatment was 5.25. No significant relationship was detected between pretreatment and posttreatment pain score. Only one patient noted mild side effect (dizziness). Conclusions: This retrospective pilot study provides no preliminary evidence that Gabapentin has effect in the management of BMS. However, further research (well-designed, randomized, and controlled trial with large sample) would be needed to investigate the efficacy of Gabapentin in treatment of BMS.

Effects of Applying a Vibration Stimulation to Paretic Side and Non-Paretic Side on Balance and Gait in Stroke Patients: a Pilot Study

  • Jeong, Ho Jin;Park, Sung Hwan;Jeon, Jong Yun;Kim, Byeong Geun
    • The Journal of Korean Physical Therapy
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    • v.34 no.5
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    • pp.193-197
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    • 2022
  • Purpose: The purpose of this pilot study was to assess the feasibility of a proposed study "To investigate the effects of applying a vibration stimulation to the paretic and non-paretic sides on balance and gait in stroke patients" before proceeding with the main study. Methods: A total of 30 patients who had suffered a stroke and who met the selection criteria participated in this study. However, only 14 patients completed the study. The study subjects were randomly assigned to vibration stimulation on either both sides (B group) or the paralyzed side (P group). The interventions were applied for six weeks. The patients were assessed using the Berg balance scale (BBS), Timed up and go (TUG), 10-meter walk (10 MW), and 6-minute walk (6 MW) tests. Results: There was a significant difference before and after the application of vibration stimulation in the BBS, TUG, 10MW, and 6 MW tests in the B group (p<0.05). Similarly, there was also a significant difference observed in the 10 MW and 6 MW tests in the P group (p<0.05). The difference between the two groups was not significant in the BBS, TUG, 10 MW, and 6 MW tests (p>0.05). Conclusion: This pilot study suggests that it would be feasible to conduct a large-scale randomized controlled trial (RCT) to examine the effects of applying a vibration stimulation to the paretic and non-paretic sides, on the balance and gait in stroke patients.

Effect of trunk training in wheelchair on fall efficacy, fall risk, activities of daily living in acute stroke patients: Randomized controlled pilot study (휠체어 몸통 훈련이 급성기 뇌졸중 환자의 낙상 효능감, 낙상 위험도, 일상생활활동에 미치는 영향: 무작위 대조군 예비 연구)

  • Jung, Kyeoung-Man;Jung, Yu-Jin
    • Journal of Korean Physical Therapy Science
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    • v.29 no.3
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    • pp.1-11
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    • 2022
  • Background: The aim of this randomized controlled pilot study was to determine the effect of trunk training in wheelchair on fall efficacy, fall risk and activities of daily living in acute stroke patients. Design: Randomized controlled pilot trial. Methods: The study included 18 patients with acute stroke who were randomly allocated to an experimental group (EG) (n=9) and a control group (CG) (n=9). Patients in the EG group received general rehabilitation therapy combined with trunk training in wheelchair for 20min, whereas CG group received general rehabilitation therapy combined with bicycle training for 20min. Both groups performed the exercise 5 times a week for 3 weeks. Outcomes were assessed using Korean-Fall Efficacy Scale (K-FES), Fullerton Advanced Balance Scale (FAB) and Korean-Modified Barthel Index (K-MBI). Results: After 3 weeks of training, both groups showed significantly improved K-FES, FAB and K-MBI (p<.05 in both groups). However, the K-FES, FAB and K-MBI in the experimental group was significantly improving than in the control group (p<.05). Conclusion: These findings indicate that trunk training in wheelchair may be effective at decreasing fall risk and improving activities of daily living in acute stroke patients. Therefore, trunk training in wheelchair may be recommended as an intervention in reducing the incidence of fall risk in acute stroke patient.

Design of Optimal Capacity Coefficients of Flow Control Valves in the Hoist Hydraulic System Using the Complex Method (콤플렉스법에 의한 호이스트 유압회로 유량제어밸브의 최적유량계수 설계)

  • Lee, S.R.
    • Transactions of The Korea Fluid Power Systems Society
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    • v.4 no.1
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    • pp.1-6
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    • 2007
  • The typical hydraulic system of hoist is composed of a hydraulic supply unit, a directional control valve, two pilot operated check valves, two flow control valves. The capacity coefficients of flow control valves should be adjusted for the hoist to operate at moderate speed and minimize the hydraulic energy loss. However, it is difficult to adjust the four capacity coefficients of flow control valves by trial and error for optimal operation. The steady state model of the hoist hydraulic system is derived and the optimal capacity coefficients of flow control valves are obtained using the complex method that is one kind of constrained direct search method.

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Kangjin Substation 80MVA UPFC Trial Operation (강진 변전소 80MVA UPFC 시험운전)

  • Yoo, H.H.;You, I.D.;Suh, I.Y.;Yoon, J.S.;Jeon, Y.S.;Kwak, N.H.;Yang, J.W.
    • Proceedings of the KIEE Conference
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    • 2003.07a
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    • pp.528-530
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    • 2003
  • UPFC Pilot plant project의 결과물로써 설계, 제작된 80MVA급 UPFC(Unified Power Flow Controller)는 현재 강진변전소 강진-장홍 154kV 선로에 설치되어 commissioning 시험을 완료하고 시험 운전되고 있다. UPFC는 기존에 수동적으로 제어하였던 선로의 전압, 임피던스 및 위상각을 능동적으로 제어함으로써 전력공급의 신뢰성 및 유연성을 높일 수 있다. 이러한 기능을 갖는 UPFC의 시험 운전을 통하여 UPFC의 기기자체의 성능을 검증하고 기기의 운전 영역의 변화가 인근의 계통에 미치는 영향에 대하여 조사하였다.

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Effect of Kinesiology Taping of the Middle Back on Static Balance in Hemiplegic Stroke Patients: A Pilot Study

  • Kim, Bokyung
    • Journal of International Academy of Physical Therapy Research
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    • v.12 no.2
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    • pp.2354-2358
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    • 2021
  • Background: Stroke is a neurological disorder characterized by an impaired static balance. A change in poor posture after stroke may worsen static balance. The balance control through an upright posture may include kinesiology taping of the middle back. Objectives: To investigated the effect of kinesiology taping of middle back on static balance in patients with stroke. Design: A randomized controlled trial. Methods: A total of 10 patients with stroke were divided into two groups. The experimental and control groups received kinesiology taping and placebo taping of the middle back, respectively. After 24 h, static balance (i.e., sway area and path length) was measured in closed eyes condition. Results: The experimental group (kinesiology taping group) showed a significant decrease in sway area and path length after the intervention. In addition, kinesiology taping group showed a significant decrease in sway area and path length compared to the control group. Conclusion: Kinesiology taping of the middle back can improve static balance in stroke patients.

Development and Tree-Dimensional Kinematic Analysis of the Dual Chamber-based Drinking Aid for Stroke Patients: A Prospective Pilot Study (이중 체임버 구조가 내장된 뇌졸중 환자용 컵의 개발과 3차원 동작분석을 통한 운동 형상학적 유용성 검증: 전향적 예비연구)

  • Heo, Seo Yoon;Kim, Kyeong-Mi
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.12
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    • pp.180-190
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    • 2016
  • This prospective pilot clinical trial mainly focuses on developing dual chamber-based assistive cups which are suitable for stroke patients who have struggled with using there affected arms. It is unable to provide motor and sensory enhancement during drinking activities and to examine the feasibility of the devices for acute phase, even for chronic stroke survivors. The stroke patients(n=16; male=8, female=8), in this trial, were provided informed consent to the investigation. All the individuals participated in 1 weeks of training for using cups, randomized over dedicated dual chamber based assistive cups(DC) or placebo-cups(PC) training. All the participants were assessed within 1 week before and after the intervention period. 3-dimensional motion analysis, sEMG(surface electromyography) and 3-dimensional trunk movement were assessed. The result presents DC data group compared with PC showed, they needed lesser ROM(range of motion) at the phase of drinking in shoulder movements and lesser muscle activities on upper trapezius, deltoid middle fiber and triceps brachii muscles, lesser tilting movement on front and back side in drinking phase, the differences were statistically significant(p<.05). Dual chamber-based assistive cup could be one of efficient way to complete ADLs(activities of daily living), especially drinking tasks, and these evidence data may contribute to determine certain rehabilitation policies related to assistive devise usage.

Efficacy of Electroacupuncture with Dysphagia Caused by Stroke - Double-blind, Randomized Controlled Trial - (중풍으로 유발된 연하 장애 환자에 대한 전침 치료의 임상 효과)

  • Kim, Min-Kyung;Lu, Hsu-Yuan;Cho, Seung-Yeon;Jung, Woo-Sang;Moon, Sang-Kwan;Park, Jung-Mi;Ko, Chang-Nam;Cho, Ki-Ho;Park, Seong-Uk
    • The Journal of Korean Medicine
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    • v.35 no.1
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    • pp.26-40
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    • 2014
  • Objectives: This study investigated the effect of electroacupuncture on swallow function in stroke patients with dysphagia. The purpose was to determine whether electroacupuncture could improve swallow function and quality of life for patients with dysphagia caused by stroke. A pilot double-blind, randomized controlled trial design was used Methods: A total of 17 stroke patients with dysphagia were recruited to this study, 8 assigned to the swallowing electroacupuncture (SE) group and 9 to the control group. Swallowing electroacupuncture was assessed for 5 Hz electrical or sham stimulation for 20 min duration 3 times a week. Outcome measurements were DOSS, 14-item questionnaire from the SWAL-QOL, NIHSS and MBI. Assessment was carried out for baseline, 2 weeks and 4 weeks Results: In the 2 weeks follow up data, the study group showed significant difference in DOSS and SWAL-QOL compared with the baseline. The study group also showed significant difference in DOSS and SWAL-QOL compared with the control group. Similarly in the 4 weeks follow up data, the study group showed improvement tendency in DOSS and SWAL-QOL compared with baseline and also with the control. The NIHSS and MBI scores returned no significant differences. The swallowing electroacupuncture was well tolerated in all cases with no serious adverse effects. Conclusions: The findings from the pilot study indicated that electroacupuncture has significant effects on improvement in swallowing function and quality of life. With both inpatients and outpatients, further larger and longer-term follow-up study is needed to confirm this suggestion.