• 한국약용작물학회지
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• 제27권2호
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• pp.143-150
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• 2019

Background: Skin is an organ that protects the human body from various environmental stimuli that can induce immune system activation. Skin aging can be largely divided into two categories: physiological aging, which is caused by the a decreased physiological function of the skin and structural changes with aging, and photoaging, which is caused by the chemical stress induced by external stimuli such as ultraviolet (UV) radiation. Methods and Results: The objective of this study was to investigate the anti-wrinkle and UV protective effect of catechin-rich green tea extract (CGTE) in activated keratinocyte (HaCaT cells) and UV-induced skin damage in hairless mice. The results showed that CGTE inhibits the tumor necrosis factor-alpha interferon-gamma ($TNF-{\alpha}+IFN-{\gamma}$)-induced expression of matrix metalloproteinase (MMP)-1 in HaCaT cells. In addition, the CGTE treatment significantly reduced wrinkle formation, epidermal thickness, collagen deposition, and transepidermal water loss in dorsal skin irradiated with UVB. However, the ${\beta}$-glucosidase activity was significantly increased. The CGTE treatment inhibits mRNA expression and enzyme activity of MMP-2 and MMP-9 in the dorsal skin irradiated with UVB. Conclusions: It is expected that CGTE can be effectively used as a functional food and cosmetic ingredient to improve skin moisture retention and reduce wrinkle formation.

• 감성과학
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• 제3권2호
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• pp.17-28
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• 2000

Psychoacoustic characteristics of automobile horns play significant role in resulting subjective evaluation and psychphysiological reactions. However, comparison and differentiation of physiological responses to commercially available horns is a complicated task due to the small contrast in technical features of horns and the influence of such processes as habituation on physiological outcome with the increased number of auditory stimulation trials. In a study on 10 college students, there was performed comparative analysis of reactivity of physiological responses mediated by central and autonomic nervous systems in order to identify the role of habituation on decrement of psychophysiological responsivity and assess the ability to differentiate subjectively most and least preferred, as well as most and least appropriate horns according to physiological manifestations. The EEG and autonomic responses to 7 automobile horns were analyzed during 3 blocks of trials, with varying order of stimuli and changed acoustic parameters of horns in each block. Thus, responses were analyzed for totally 21 trials of auditory stimulation. It was shown that electrodermal and cardiovascular responses have different reactivity patterns to repeated stimulation: skin conductance measures habituated, cardiac reactivity showed no signs of habituation, and the vascular response demonstrated sensitization. The temporal EEG exhibited marked habituation of fast beta band power, while alpha-blocking effect did not habituate during the course of experiment. Differentiation of physiological responses of most and least preferred and appropriate horns was possible in our study, however, some cardiovascular reactivity measures differentiated during the entire course of the experiment, while EEG and electrodermal parameters showed significant differences only during first block of trials, and were later affected by the habituation.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.370-373
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• 1997

We are exposed to the various external stimuli input from the environment, which cause emotional changes based on the characteristics of the stimuli. Unfortunately there are no quantitative results on relationship between human sensibility and the characteristics of physiological signals. The objective of this study was to quantify EEG signals evoked by auditory stimulation based on the assumption that the analysis of the variability on the characteristics of the EEG waveform may provide the significant information regarding changes in psychological states of the subject. The experiment was devised with seven experimental conditions, which are control and six different types of auditory stimulation. Six subjects were used to obtain EEGs while introducing auditory stimulation. Wavelet transformation was employed to analyze the EEG signals. The results showed that the reconstructed signals at the decomposition level revealed the different energy value on the EEG signal. Also, general patterns of EEG signals in rest state compare with negative and positive stimulus were found. This study could be extended to establish an algorithm which distinguishes psychophysiological states of the subjects exposed to the auditory stimulation.

• 인지과학
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• 제9권1호
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• pp.13-29
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• 1998

이 문헌 연구는 정보처리 기제 중 자동적인 처리과정의 원리로 다양한 정서 자극에 대한 반응양식이 과연 설명될 수 있을지를 타진해 보고자 한다. 인지적인 판단이 필요한 통제과정이 전혀 개입되지 않고서도 정서 유발 자극이 Bargh(1989)가 제시한 자동처리의 원리에 따라 암묵적으로 처리될 수 있을 것인가$\ulcorner$ 몇몇 연구들은 정서 유발 자극에 대한 자동적인 처리과정은 의미론적인 처리과정보다 훨씬 우선적이며 즉각적으로 처리된다고 주장한다. 자각이 없는 상태에서도 정서 가를 파악하는 현상은 우리의 정보처리과정 중 의식적이며 인지적인 개입이 필요한 명시적인 지식 체계에 의해서가 아니라 스스로의 자각이 없이도 처리가 이루어지는 암묵적인 지식의 체계에 의해 담당될 것이라 이해할 수 있을 것이다. 이 연구에서는 이러한 암묵적인 기억과정의 원리와 그에 대한 생리학적인 근거도 제시함으로써 정서가 가미된 정보의 처리과정이 어떠한 경로를 통하여 이루어질 지에 대해 요약하여 보았다.

• 대한인간공학회지
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• 제17권1호
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• pp.91-102
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• 1998

History of the Sensibility Ergonomics is explained. Concepts, definition, and research methods on the human sensibility are proposed for systematic applications of human sensibility studies to product and environment developments. Sensibility Ergonomics was born in socio-technological environments where consumers required aesthetic and satisfactory products in addition to useful and usable ones, and manufactures were trying to develop consumer-oriented, user-friendly products. Sensibility Ergonomics is defined as "multi-disciplinary and inter-disciplinary processes for developing products and environment as usable, comfortable and satisfactory with the information on human sensibility." Human sensibility is functionally defined as "feelings generated when perceived sensory and information stimuli are reflected from memory which has been accumulated through personal experiences." Human sensibility is affected by at least three factors: personal, social, and cultural. Consumers evaluate products in three aspects : functional, sensorial, and cultural sensibilities. Human sensibility is personal, dynamic, and ambiguous. It is generated reflectively and intuitively against external stimuli. No Physiological responses are accompanied, and one cannot control his/her sensibility. However, the sensibility affects the decision making or behavior of the person. To understand the human sensibility many inter-disciplinary methods should be used instead of one-variable approach. Micro-scopic studies such as Questionnaire, interview, behavioral analysis, and psychophysiological experiments can be performed. In addition, social and cultural studies are essential to understand an individual's sensibility. Results of sensibility studies can be applied to setup new interactions between human and machine through sensible(or affective) human-machine (computer) interfaces. Human-oriented and user-friendly products can be made with the information on human sensibility.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.455-458
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• 1997

We are exposed to the various external stimuli input from the environment, which cause emotional changes based on the characteristics of the stimuli. Unfortunately, there are no quantitative results on relationship between human sensibility and the characteristics of physiological signals. The objective of this study was to quantify EEG signals evoked by visual stimulation based on the assumption that the analysis of the variability on the characteristics of the EEG waveform may provide the significant information regarding changes in psychological states of the subject. Seven university students were participated in this study. The experiment was devised with eleven experimental conditions, which are control and ten different types of visual stimulation based on IAPS (International Affective Picture Systems). Wavelet transformation was employed to analyze the EEG signals. Most positive and negative emotional response were compared in pairs. The results showed that the reconstructed signals at the decomposition level revealed the different energy value on the EEG signals. Also, general patterns of EEG signals in rest state compare with positive and negative stimulus were found. This study could be extended to establish an algorithm which distinguishes psychophysiological states of the subjects exposed to the visual stimulation.

• 대한인간공학회:학술대회논문집
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• 대한인간공학회 1997년도 추계학술대회논문집
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• pp.477-481
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• 1997

We are exposed to the various external stimuli input from the environment, which cause emotional changes based on the characteristics of the stimuli. Unfortunately, there are noquantitative results on relationship between human sensibility and the characteristics of physiological signals. The objective of this study was to quantify EEG signals evoked by visual stimulation based on the assumption that the analysis of the variability on the characteristics of the EEG waveform may provide the significant information regarding changes in psychological states of the subject. Seven university students were participated in this study. The experiment was devised with eleven experimental conditions, which are control and ten different types of visual stimulation based on IAPS(International Affective Picture Systems). Seven subjects were used to obtain EEGs while introducing visual stimulation. Wavelet transformation was employed to analyze the EEG signals. Most Positive and negative emotional response were pairely compared. The results showed that the reconstructed signals at the decomposition level revealed the different energy value on the EEG signals. Also, general patterns of EEG signals in rest state compare with negative and positive stimulus were found. This study could be extended to estabish an algorithm which distinguishes psychophysiological states of the subjects exposed to the visual stimulation.

• 동의신경정신과학회지
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• 제22권4호
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• pp.169-183
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• 2011

Objectives : This study explores perspectives, reasons, functions of dreams in order to develop a treatment model. Methods : We searched CNKI, KISS, NDSL. Papers published since 2002, which are classified in categories. Results : 1. The Recognitions about the dream of Oriental Medicine is based on "Hwangjenaegyeong Eumsabalmong(黃帝內經 淫邪發夢)". 2. By each era, There are a variety of etiological causes, stages. 3. Dreams are generated by the internal stimuli Physiological activities of the Jangbu(臟腑),Deficiencies of yin and yang(陰陽), Pathological changes in the Jangbu(臟腑), Pathology products, external stimuli Yukeum(六淫), Eumsiksang(飮食傷), and unusual feelings. 4. Spirit(神) comes from brain(腦), not heart(心). So what we call brain spirit(腦神) is right. Dreams are the mental activity related to the brain. 5. Dreams are the reflection of the pathological changes of the human body. And it shows the development, changes and prognosis of disease. Dreams sometimes illustrate the incidence of the disease Conclusions : We organized perspectives, Causes and Functions of dreams mentioned in Oriental Medicine Literatures. Health is closely related to the dream. Therefore, we propose that the dream is worth for the diagnosis and treatment in oriental medicine.

• 센서학회지
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• 제32권6호
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• pp.340-351
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• 2023

Wearable sensors designed for strain, pressure, and temperature measurements are essential for monitoring human movements, health status, physiological data, and responses to external stimuli. Notably, recent research has led to the development of high-performance wearable sensors using innovative materials and device structures that exhibit ultra-high sensitivity compared with their commercial counterparts. However, the quest for accurate sensing has identified a critical challenge. Specifically, the mechanical flexibility of the substrates in wearable sensors can introduce interference signals, particularly when subjected to varying external stimuli and environmental conditions, potentially resulting in signal crosstalk and compromised data fidelity. Consequently, the pursuit of non-interference sensing technology is pivotal for enabling independent measurements of concurrent input signals related to strain, pressure, and temperature, ensuring precise signal acquisition. In this comprehensive review, we present an overview of the recent advances in noninterference sensing strategies. We explore various fabrication methods for sensing strain, pressure, and temperature, emphasizing the use of hybrid composite materials with distinct mechanical properties. This review contributes to the understanding of critical developments in wearable sensor technology that are vital for their ongoing application and evolution in numerous fields.

• 대한불안의학회지
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• 제4권2호
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• pp.99-103
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• 2008

Objectives : The authors sought to examine the differences in the number of P300 detected by subjects in experimental and control groups when exposed to relevant stimuli. In addition, the authors tried to determinethe subjects' reaction time when asked to respond to relevant stimuli. Methods : The subjects were 20 informed female volunteers aged 22-38 years (median age : 24). Relevant stimuli (concealed information) were created by unknowingly exposing the two groups to obscene pictures and semantic questions. The number of P300 detected and the length of reaction time were compared between the two groups. Results : Contrary to theauthors' expectations, there were no significant differences in the number of P300 detected or in the length of reaction time between the two groups. Conclusions : These results indicate that, unlike a polygraph test, concealed information tests adopting P300 and reaction time as major physiological responses ofsubjects exposed to meaningful personal information might not serve as a valid practical tool in the field of criminal psychology. However, further studies involving a greater number of subjects are needed before a final conclusion regarding the validity of this new type of concealed information test can be drawn.