• Journal of Korean Society for Atmospheric Environment
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• v.7 no.3
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• pp.219-226
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• 1991

Results from study on physiological responses to $SO_2$ of Quercus spp. selected for restoration of vegetation damaged by air pollution in the field study were as follows. Tolerance of Quercus aliena, Q. acutissima and Q. mongolica used in this study to $SO_2$ was higher in that order and tolerance of these plants to $SO_2$ was high comparatively among trees composing of major forest vegetation of Korea including natural forests and plantations. Stomatal resistance of these plants was increased after exposure to $SO_2$ and range of increase was different among species. From discrepancy between order of tolerance to $SO_2$ and range of increase in stomatal resistance, we were estimated that resistance mechanisms of Quercus spp. were different among species as mechanism originated in avoidance and resistance, respectively. Water potential of plant leaves reduced after exposure to $SO_2$, degree of reduction accorded with order of tolerance to $SO_2$. Reduction of water potential of plants after exposure to $SO_2$ was initiated before appearance of visible damage in plant leaves and water potential of plants exposed to $SO_2$ of low concentration, in which plants were not showed viaible damage was also reduced.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.6
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• pp.1524-1527
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• 2003

In this study, we demonstrated the antioxidant effect of the Caesalpinia sappan L. extract through the scavenging effect against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and the protective effect on protein damage and PC12 cells against cupric ion/hydrogen peroxide. Its IC/sub 50/ value of the scavenging effect against DPPH radical was 7.7 ㎍. Protection of its extract against oxidative bovine serum albumin (BSA)damage induced by hydrogen peroxide was more effective than that of vitamin C. The protective effect on PC12 cells by hydrogen peroxide was shown to be more potent in is extract than in vitamin C. DNA fragmentation analysis also supports this result.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.4
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• pp.733-739
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• 2008

It was said that the epigastric region was the outbreak region of chest bind on Shanghanlon. But successive medical men annotated the epigastric region as the chest, which caused the misunderstanding that chest bind was a chest trouble. However Youzaijing, a medical man in Qing dynasty, presented that the epigastric region meant stomach and the middle of stomach did intestines, comparing Dachengqi-tang with Daxianxiong-tang. This view agreed with Huatuo's six-region-transmutation theory. Taojiean and Zhangjingyue also criticized on the six-meridian-transmutation theory, proposing that the change of cold damage didn't go by the fixed rules. This reflected the oriental medical pathologic view that pathogen invaded and advanced to the weak region by the relations between healthy qi and pathogen, and it criticized on the doctrinarian interpretation of Shanghanlon as Neijing. Huatuo insisted that stomach was the final stage of cold damage by presenting that theory. And this theory became a philological basis on Youzaijing's pathologic view.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.1-8
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• 2010

They have brought many inconsistencies by making much of Wang Sukhwa's six-meridian-transmutation-theory based on Yeollon, Somun in Oriental traditional medicine. On this many medical men such like Hwa Ta have raised objections to that or insisted on its repeal. Wang Geungdang and Yang Soi posed the problem of editing tables of contents, Bang Yujip and Ga Geum etc. gave explanations of fields of six-meridian, Un Cheolcho and Jang Gyeongak etc. presented cause and direction of transmutation. And Gilik Dongdong insisted on its repeal. Sanghannon was the theory that was arranged various experiences of acute epidemic diseases. But they didn't recognize the differences between analogous epidemic diseases, regarded as the same things in Oriental traditional medicine, and this made many inconsistencies. This is the reason why many medical men raised objections to Wang Sukhwa's six-meridian-transmutation-theory.

• Biomolecules & Therapeutics
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• v.30 no.6
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• pp.490-500
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• 2022

Aging is defined as physiological dysfunction of the body and a key risk factor for human diseases. During the aging process, cellular senescence occurs in response to various extrinsic and intrinsic factors such as radiation-induced DNA damage, the activation of oncogenes, and oxidative stress. These senescent cells accumulate in many tissues and exhibit diverse phenotypes, such as resistance to apoptosis, production of senescence-associated secretory phenotype, cellular flattening, and cellular hypertrophy. They also induce abnormal dysfunction of the microenvironment and damage neighboring cells, eventually causing harmful effects in the development of various chronic diseases such as diabetes, cancer, and neurodegenerative diseases. Thus, pharmacological interventions targeting senescent cells, called senotherapeutics, have been extensively studied. These senotherapeutics provide a novel strategy for extending the health span and improving age-related diseases. In this review, we discuss the current progress in understanding the molecular mechanisms of senotherapeutics and provide insights for developing senotherapeutics.

• Proceedings of the Korean Society of Crop Science Conference
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• 2000.04a
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• pp.260-261
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• 2000

• Proceedings of the Korean Society of Crop Science Conference
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• 2000.04a
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• pp.304-305
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• 2000

• Korean Journal Plant Pathology
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• v.14 no.5
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• pp.548-550
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• 1998

Bacterial soft rot caused damage to beets massively grown in Pyungchang, Kangwon province, Korea. The affected roots and stems became cream colored and slimy, and turned black, causing the plants to become wilt and die. The casual organism isolated from the infected plants was identified as Erinia carotovora subsp. carotovora based on physiological and biochemical characteristic, and the results of the Biolog program (Biolog Inc., U.S.A.). E. carotovora subsp. carotovora is the first discribed bacterium which causes bacterial soft rot on beet in Korea.

• Proceedings of the Korean Society of Toxicology Conference
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• 2001.10a
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• pp.137-138
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• 2001

There has been accumulating evidence for the association of inflammatory tissue damage with the process of cancer development. Cyclooxygenase (COX), an important enzyme involved in mediating the inflammation, catalyzes the formation of prostaglandins (PGs) from arachidonic acid. There are two isoforms of COX, designated as COX-l and COX-2. COX-l is a housekeeping enzyme which is constitutively expressed and is thought to be involved in maintaining physiological functions.(omitted)

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1777-1783
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• 2004

This study was conducted to determine the effects Wonjiseokchangpo-san on brain damage in transient focal cerebral ischemia. Rats were used for testing in the following three models: Morris Water Maze, Eight-Arm Radial Maze, and Histochemistry. In the Morris Water Maze Model, the Wonjiseokchangpo-san group showed significant decrease in the 3rd and 6th training session compared with the ischemia group. A retention test, in the Morris Water Maze Model, was performed on the 7th day without the escape platform. The Wonjiseokchangpo-san group showed significant increase compared to the ischemia group. In the Eight-Arm radial Maze model, the Wonjiseokchangpo-san group showed significant decrease in the error rate compared to the ischemia group. In the density of hippocampal CA1 cell of the cresyl violet-stained section, the Wonjiseokahangpo-san group showed significant increase compared to the ischemia group. These results suggest that Wonjiseokchangpo-san may have a significant protective effect on brain damage and cognitive dysfunction in transient focal cerebral ischemia.