• PNF and Movement
• /
• 제11권1호
• /
• pp.63-68
• /
• 2013

Purpose : The purpose of this study was to examine changes in spatiotemporal gait parameters(STGPs) in healthy adults before and after a immediate intervention of a Mulligan taping program(MTP). Methods : A total of 12 healthy adults(mean age, 20.82 years; age range, 19-24 years) participated in the study. performance was assessed by recording changes in the STGPs using GaitRite. comparisons of changes in the STGPs at pre-intervention and at dischange were analyzed using the Wilcox signed rank test and Mann-Whithney U test. Results : There was a significant improvement in the outcome measures of STGPs(stride length, velocity) after immediate of MTP(p<0.05). However, no significant different pre-test and post-test step width, toe angle(p>0.05). Conclusion : Participants in a MTP improves STGPs, thereby increasing the ability of healthy adults to maintain gait. MTP appears to be a safe and efficacious, noninvasive treatment modality for patients with knee joint disease.

• BMB Reports
• /
• 제54권5호
• /
• pp.233-245
• /
• 2021

In eukaryotes, the genome is hierarchically packed inside the nucleus, which facilitates physical contact between cis-regulatory elements (CREs), such as enhancers and promoters. Accumulating evidence highlights the critical role of higher-order chromatin structure in precise regulation of spatiotemporal gene expression under diverse biological contexts including lineage commitment and cell activation by external stimulus. Genomics and imaging-based technologies, such as Hi-C and DNA fluorescence in situ hybridization (FISH), have revealed the key principles of genome folding, while newly developed tools focus on improvement in resolution, throughput and modality at single-cell and population levels, and challenge the knowledge obtained through conventional approaches. In this review, we discuss recent advances in our understanding of principles of higher-order chromosome conformation and technologies to investigate 4D chromatin interactions.

• Journal of Oral Medicine and Pain
• /
• 제24권4호
• /
• pp.397-410
• /
• 1999

In order to obtain the basic data concerning the optimal parameters in using Nd:YAG laser as a therapeutic modality to dentinal hypersensitivity, the author prepared 3 sections of sound dentin and 10 sections of sclerotic dentin with thickness of $0.5mm{\pm}0.1mm$ from human extracted teeth of anteriors and premolars, and applied the laser energy from a fiberoptic delivered, free running, pulsed Nd:YAG laser (wavelength 1064nm, pulse duration $120{\mu}sec$, fiber diameter $320{\mu}m$) to surfaces of sound and sclerotic dentin sections for 1 second with contact/unidirectional moving mode of the fiber under speed of 3mm~4mm/sec and parameters of 0.5W/10Hz, 1.0W/10Hz, 1.5W/10Hz, 2.0W/10Hz: $62J/cm^2$, $124J/cm^2$, $187J/cm^2$, $249J/cm^2$. The author comparatively evaluated the characteristics of ultrastructural changes on surfaces of sound and sclerotic dentin sections irradiated by the pulsed Nd:YAG laser using the scanning electron microscopy. A fairly ill-defined bordered surface of partially closed and melted dentinal tubules can be seen on the scanning electron microscopic feature of the sound dentin surface irradiated by the pulsed Nd:YAG laser with energy density of $62J/cm^2$. The physical modification of sound dentin surface extensively occurred depended on the increase of energy density from $62J/cm^2$ to $124J/cm^2$, $187J/cm^2$, $249J/cm^2$. While, a fairly well-defined bordered surface of partially closed and melted dentinal tubules with thickened peritubular dentin can be seen on the scanning electron microscopic feature of the sclerotic dentin surface irradiated by the pulsed Nd:YAG laser with energy density of $62J/cm^2$. The physical modification of sclerotic dentin surface of a fairly rough, shallow depression with many cracks, thickened peritubular dentin and structureless dentinal tubules extensively occurred depended on the increase of energy density from $62J/cm^2$ to $124J/cm^2$, $187J/cm^2$, $249J/cm^2$ compared to those of sound dentin surface irradiated by the pulsed Nd:YAG laser under the same parameters. Therefore, it is recommended that the pulsed Nd:YAG laser as a therapeutic modality to dentinal hypersensitivity should be applied with the less energy density than $62J/cm^2$ on the sound dentin surface, and its energy density on the partially sclerotic dentin surface should be lower than that on the sound dentin surface to preserve tooth from unnecessary excessive structural destruction.

• The Journal of Korean Physical Therapy
• /
• 제22권5호
• /
• pp.103-108
• /
• 2010

Purpose: The aim of this study is to investigate whether motor cortex excitability by transcranial direct current stimulation (tDCS) over primary motor cortex (M1) affects motor performance of serial reaction task. Methods: Cathodal, anodal and sham tDCS (1 mA) are applied over right M1 of 24 subjects for 30 minutes including 11minutes for task period time. We applied two electrodes at the same position to both an experimental group and a sham-controlled group, and we made 2 groups recognize to be applicated of stimulation. Flexion, extension of wrist and thumb flexion are carried out following colors of arrows on the monitor. Serial reaction time task was applied to confirm the difference of the reaction time between 2 groups. Results: Reaction time is decreased in both tDCS-group and Sham-controlled tDCS group, and the degree of reduction is much greater in the post-test than pre-test. Reduction of reaction time between groupsis statistically significant. Conclusion: We consider that anodal tDCS increased the cortical excitability of the underlying motor cortex and it can be helpful to modulate motor performance. It seems that tDCS is an effective modality to modulate brain function, and it will be great help to mediate strategy for the brain injury patients.

• 한국산학기술학회논문지
• /
• 제13권7호
• /
• pp.3030-3036
• /
• 2012

본 연구는 강제 양압식 호흡훈련이 기관절개관을 삽입한 뇌졸중 환자의 호흡능력 및 기침능력에 미치는 효과에 대하여 알아보고자 실시하였다. 연구대상은 기관절개관을 삽입한 뇌졸중 환자 10명으로 하였으며, 대상자는 강제 양압식 호흡훈련을 20분씩 주 5회 8주간 실시하였다. 훈련 전, 훈련 4주 후 그리고 8주 후 대상자의 노력성 폐활량, 1초간 노력성 호기량, 노력성 폐활량비 그리고 도수 보조 최대 기침유량을 측정하였으며 기간에 따른 호흡능력과 기침능력을 알아보고자 반복측정 분산분석법을 이용하였다. 연구 결과 훈련기간에 따라 대상자의 노력성 폐활량, 1초간 노력성 호기량, 도수 보조 최대 기침유량은 유의하게 증가하였다. 따라서 강제 양압식 호흡훈련은 기관절개관을 삽입한 뇌졸중 환자의 호흡능력 및 기침능력을 증진시켜 기관절개관을 제거하는데 유용한 훈련방법이라 할 수 있다.

• Journal of Preventive Medicine and Public Health
• /
• 제51권5호
• /
• pp.227-233
• /
• 2018

Objectives: Chronic diseases, including back pain, result in significant patient morbidity and societal burden. Overall improvement in physical fitness is recommended for prevention and treatment. Walking is a convenient modality for achieving initial gains. Our objective was to determine whether neighbourhood walkability, acting as a surrogate measure of physical fitness, was associated with the presence of chronic disease. Methods: We conducted a cross-sectional study of prospectively collected data from a prior randomized cohort study of 227 patients referred for tertiary assessment of chronic back pain in Ottawa, ON, Canada. The Charlson Comorbidity Index (CCI) was calculated from patient-completed questionnaires and medical record review. Using patients' postal codes, neighbourhood walkability was determined using the Walk Score, which awards points based on the distance to the closest amenities, yielding a score from 0 to 100 (0-50: car-dependent; 50-100: walkable). Results: Based on the Walk Score, 134 patients lived in car-dependent neighborhoods and 93 lived in walkable neighborhoods. A multivariate logistic regression model, adjusted for age, gender, rural postal code, body mass index, smoking, median household income, percent employment, pain, and disability, demonstrated an adjusted odds ratio of 2.75 (95% confidence interval, 1.16 to 6.53) times higher prevalence for having a chronic disease for patients living in a car-dependent neighborhood. There was also a significant dose-related association (p=0.01; Mantel-Haenszel chi-square=6.4) between living in car-dependent neighbourhoods and more severe CCI scores. Conclusions: Our findings suggest that advocating for improved neighbourhood planning to permit greater walkability may help offset the burden of chronic disease.

• The Journal of Korean Physical Therapy
• /
• 제24권2호
• /
• pp.82-89
• /
• 2012

Purpose: In this study, the effects of stability exercise, extracorporeal shock wave therapy, and taping on pain and function in patients with myofascial pain syndrome of upper trapezius were compared. Methods: The subjects were divided into the stability exercise, ESWT and the taping treatment group and the clinical outcomes were evaluated by visual analog scale (VAS), pressure pain threshold (PPT) and a constant-murley scale (CMS) at pre-treatment and post-treatment. Paired t-test and ANOVA was used for statistical analysis. Results: All groups were statistical significance in the change in visual analog scale (p<0.05). The difference between the ESWT group and taping group was statistical significance in the change in pressure pain threshold (p<0.05) except for the taping group. Using the constant-murley scale, the stability exercise group showed a significant decrease in pain, and a significant increase in ROM, ADL, strength, total score of shoulder (p<0.05); however, the ESWT group showed no difference on ADL. In addition, there was no difference in strength for the taping group. The comparison of the effect between the stability exercise group, ESWT group and taping group in CMS showed a statistical significant difference in pain, ADL and ROM (p<0.05). Conclusion: These results indicate that stability exercise, ESWT and taping could be considered an effective and efficient treatment modality for myofascial pain syndrome of upper trapezius.

• Journal of Acupuncture Research
• /
• 제18권5호
• /
• pp.11-23
• /
• 2001

Objective : This study is designed to evaluate the clinical effect of the oriental medical treatment (Ex: chuna, physical theraphy, acupuncture, moxibustion, herb medicine, etc.) on patient of scoliosis. Methods : We investigated 12 patients with scoliosis who visited to Department of Acupunture & Moxibustion, Tae gu Oriental Hopital of Kyung San University from January 2000 to September. 12 patients had a diagnosis of scoliosis by X-ray. We treated 12 patients by the oriental medical treatment (Ex: chuna, acupuncture, physical theraphy, moxibustion, herb medicine, etc.)and they were evaluated with post treatment X-ray findings. Results : 1. We investigated 6 female and 6 male patients. The most commom distribution of age was 30's. 2. In the scoliosis angle : before treatment, the average scoliosis angle was $13.56^{\circ}$ but after treatment, it was decreased to $9.31^{\circ}$ and the mean correctability was 33.47%. 3. The more servious the symptoms were, the lesser the correction rate was. It was decreased in the order of Gr I, Gr II, Gr III and Gr IV. 4. The larger the scoliosis angle and the degree of rotation were, the lesser the correction rate was. Conclusion : These results suggest that the oriental medical treatment (Ex: chuna, acupuncture, physical theraphy, moxibustion, herb medicine, etc.) was effective treatment modality on patient of scoliosis.

• 한국운동역학회지
• /
• 제24권4호
• /
• pp.399-415
• /
• 2014

The aim of this study was to investigate the effect of resistance training with and without whole-body vibration(WBV) on the biomechanical properties of the plantarflexor in the elderly women (>60 yrs., n=35). Thirty-five volunteers were randomly assigned to a resistance training with WBV group (RVT, n=14), a resistance training without WBV (RT, n=11), and a non-training control group (CON, n=10). The RVT and the RT groups participated in the training sessions three times a week for 8 weeks, followed by a 4-week detraining period. The CON group was instructed to refrain from any type of resistance training. To assess strength and activation of the plantarflexor muscles, maximum isometric ankle plantarflexion torque and muscle activation of the triceps surae muscles were measured using dynamometry, twitch interpolation technique and electromyography at four different ankle joint angles. Also, the lower extremity function was assessed by vertical jumping. The measurements were performed prior to, 2 and 8 weeks after the training and after a 4-week detraining period. Following the 8-week training sessions, an increase in the isometric plantarflexion strength was found to be greater for the RVT compared with the RT group (p<.05). Muscle inhibition was significantly decreased after training than before training only for the RVT (p<.05). Following the detraining period, a decrease in isometric plantarflexors strength and a increases in muscle inhibition were significantly less in the RVT compared with the RT group. In conclusion, the exercise with WBV is a feasible training modality for the elderly and seems to have a boosting effect when used with conventional resistance training.

• Physical Therapy Rehabilitation Science
• /
• 제8권1호
• /
• pp.22-31
• /
• 2019

Objective: For knee osteoarthritis (OA), there is a demand for alternative modalities in order to delay surgery and to avoid the side effects of medications. This study compared the effects of applying seaweed pack and mudpack for the treatment of knee OA. Design: Randomized controlled trial. Methods: Twenty-five patients with knee OA who satisfied the criteria were included. The patients were divided into two groups according to the treatment method: mudpack (n=12) and seaweed pack (n=13). The two groups were treated for 20 minutes, twice a day for five continuous days at the Ocean Healing Center at Wando Island, South Korea. Participants were assessed by clinical scores (Western Ontario and McMaster Universities Osteoarthritis Index, Hospital for Special Surgery Knee Score, Knee injury and Osteoarthritis Outcome Score and 36-Item Short Form Health Survey) and lab results (erythrocyte sedimentation rate, C-reactive protein, insulin-like growth factor-1 [IGF-1], tumor necrosis $factor-{\alpha}$ [$TNF-{\alpha}$]) during the follow-up period. Results: For the most part, clinical scores improved after therapy and maintained improvements for four weeks in both groups (p<0.05). In the seaweed group, $TNF-{\alpha}$ was significantly decreased at two weeks post-therapy (p<0.05). In both groups, IGF-1 was significantly increased immediately post-therapy (p<0.05). There were no statistically significant differences after therapy between the groups in clinical scores and labs. Conclusions: Seaweed packs and mudpacks had similar positive effects for knee OA. Additionally, the seaweed pack group showed decreased levels of $TNF-{\alpha}$ at two weeks post-treatment, which may explain the reduced inflammatory reaction. For rehabilitation therapy, use of seaweed packs may serve as an alternative modality for the treatment of knee OA.