The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
권호 표지

The Effects of Transcranial Direct Current Stimulation in Motor Performance of Serial Reaction Time Task

경두개직류전류자극이 시열반응과제에 대한 운동 수행 능력에 미치는 영향

  • Kim, Chung-Sun (Department of Physical Therapy, College of Rehabilitation, Daegu University) ;
  • Nam, Seok-Hyun (Department of Rehabilitation Science, Graduate School, Daegu University) ;
  • Cho, In-Sul (Department of Rehabilitation Science, Graduate School, Daegu University)
  • 김중선 (대구대학교 재활과학대학 물리치료학과) ;
  • 남석현 (대구대학교 대학원 재활과학과) ;
  • 조인술 (대구대학교 대학원 재활과학과)
  • Received : 2010.05.31
  • Accepted : 2010.09.24
  • Published : 2010.10.25
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: The aim of this study is to investigate whether motor cortex excitability by transcranial direct current stimulation (tDCS) over primary motor cortex (M1) affects motor performance of serial reaction task. Methods: Cathodal, anodal and sham tDCS (1 mA) are applied over right M1 of 24 subjects for 30 minutes including 11minutes for task period time. We applied two electrodes at the same position to both an experimental group and a sham-controlled group, and we made 2 groups recognize to be applicated of stimulation. Flexion, extension of wrist and thumb flexion are carried out following colors of arrows on the monitor. Serial reaction time task was applied to confirm the difference of the reaction time between 2 groups. Results: Reaction time is decreased in both tDCS-group and Sham-controlled tDCS group, and the degree of reduction is much greater in the post-test than pre-test. Reduction of reaction time between groupsis statistically significant. Conclusion: We consider that anodal tDCS increased the cortical excitability of the underlying motor cortex and it can be helpful to modulate motor performance. It seems that tDCS is an effective modality to modulate brain function, and it will be great help to mediate strategy for the brain injury patients.

Keywords

References

  1. Kwon YH, Jang JS, Kim CS. Changes of cortical activation pattern induced by motor learning with serial reaction time task. J Kor Soc Phys Ther. 2009;21(1):65-71. https://doi.org/10.1589/jpts.21.65
  2. Middleton FA, Strick PL. Basal ganglia and cerebellar loops:Motor and cognitive circuits. Brain Res Brain Res Rev. 2000;31(2-3):236-50. https://doi.org/10.1016/S0165-0173(99)00040-5
  3. Jang SH, Ahn SH, Byun WM et al. The effect of transcranial direct current stimulation on the cortical activation by motor task in the human brain: An fmri study. Neurosci Lett. 2009;460(2):117-20. https://doi.org/10.1016/j.neulet.2009.05.037
  4. Alonso-Alonso M, Fregni F, Pascual-Leone A. Brain stimulation in poststroke rehabilitation. Cerebrovasc Dis. 2007;24 Suppl 1:157-66.
  5. Boggio PS, Castro LO, Savagim EA et al. Enhancement of non-dominant hand motor function by anodal transcranial direct current stimulation. Neurosci Lett. 2006;404(1-2): 32-6.
  6. Fregni F, Boggio PS, Nitsche M et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res. 2005;166(1):23-30. https://doi.org/10.1007/s00221-005-2334-6
  7. Liebetanz D, Nitsche MA, Tergau F et al. Pharmacological approach to the mechanisma of transcranial dc-stimulationinduced after-effects of human motor cortex exitability. Brain. 2002;125(Pt 10):2238-47. https://doi.org/10.1093/brain/awf238
  8. Cerruti C, Schlaug G. Anodal transcranial direct current stimulation of the prefrontal cortex enhances complex verbal associative thought. J Cogn Neurosci. 2009;21(10):1980-7. https://doi.org/10.1162/jocn.2008.21143
  9. Park RJ, Lee MY, Joe IS et al. The effects of transcranial direct current stimulation in motor performance of visuomotor task. Journal of Rehabililation Research. 2008; 12(3):39-53.
  10. Nitsche MA, Doemkes S, Karakose T et al. Shaping the effects of transcranial direct current stimulation of the human motor cortex. J Neurophysiol. 2007;97(4):3109-17. https://doi.org/10.1152/jn.01312.2006
  11. Paulus W. Transcranial direct current stimulation (tDCS). Suppl Clin Neurophysiol. 2003;56:249-54. https://doi.org/10.1016/S1567-424X(09)70229-6
  12. Oldfield RC. The assessment and analysis of handedness: The edinburgh inventory. Neuropsychologia. 1971;9(1): 97-113. https://doi.org/10.1016/0028-3932(71)90067-4
  13. Park JW, Jang SH. The difference of cortical activation pattern according to motor learning in dominant and non-dominant hand: An fmri case study. J Kor Soc Phys Ther. 2009; 21(1):81-7. https://doi.org/10.1589/jpts.21.81
  14. Debaere F, Wenderoth N, Sunaert S et al. Changes in brain activation during the acquisition of a new bimanual coodination task. Neuropsychologia. 2004;42(7):855-67. https://doi.org/10.1016/j.neuropsychologia.2003.12.010
  15. Hummel F, Celnik P, Giraux P et al. Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke. Brain. 2005;128(Pt 3):490-9. https://doi.org/10.1093/brain/awh369
  16. Hummel FC, Voller B, Celnik P et al. Effects of brain polarization on reaction times and pinch force in chronic stroke. BMC Neurosci. 2006;7:73. https://doi.org/10.1186/1471-2202-7-73
  17. Baudewig J, Nitsche MA, Paulus W et al. Regional modulation of bold mri responses to human sensorimotor activation by transcranial direct current stimulation. Magn Reson Med. 2001;45(2):196-201. https://doi.org/10.1002/1522-2594(200102)45:2<196::AID-MRM1026>3.0.CO;2-1
  18. Lang N, Nitsche MA, Paulus W et al. Effects of transcranial direct current stimulation over the human motor cortex on corticospinal and transcallosal excitability. Exp Brain Res. 2004;156(4):439-43. https://doi.org/10.1007/s00221-003-1800-2