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A Method for Estimating the Lung Clinical Target Volume DVH from IMRT with and without Respiratory Gating

  • J. H. Kung;P. Zygmanski;Park, N.;G. T. Y. Chen
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.53-60
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    • 2002
  • Motion of lung tumors from respiration has been reported in the literature to be as large as of 1-2 cm. This motion requires an additional margin between the Clinical Target Volume (CTV) and the Planning Target Volume (PTV). While such a margin is necessary, it may not be sufficient to ensure proper delivery of Intensity Modulated Radiotherapy (IMRT) to the CTV during the simultaneous movement of the DMLC. Gated treatment has been proposed to improve normal tissues sparing as well as to ensure accurate dose coverage of the tumor volume. The following questions have not been addressed in the literature: a) what is the dose error to a target volume without gated IMRT treatment\ulcorner b) what is an acceptable gating window for such treatment. In this study, we address these questions by proposing a novel technique for calculating the 3D dose error that would result if a lung IMRT plan were delivered without gating. The method is also generalized for gated treatment with an arbitrary triggering window. IMRT plans for three patients with lung tumor were studied. The treatment plans were generated with HELIOS for delivery with 6 MV on a CL2100 Varian linear accelerator with a 26 pair MLC. A CTV to PTV margin of 1 cm was used. An IMRT planning system searches for an optimized fluence map ${\Phi}$ (x,y) for each port, which is then converted into a dynamic MLC file (DMLC). The DMLC file contains information about MLC subfield shapes and the fractional Monitor Units (MUs) to be delivered for each subfield. With a lung tumor, a CTV that executes a quasi periodic motion z(t) does not receive ${\Phi}$ (x,y), but rather an Effective Incident Fluence EIF(x,y). We numerically evaluate the EIF(x,y) from a given DMLC file by a coordinate transformation to the Target's Eye View (TEV). In the TEV coordinate system, the CTV itself is stationary, and the MLC is seen to execute a motion -z(t) that is superimposed on the DMLC motion. The resulting EIF(x,y)is inputted back into the dose calculation engine to estimate the 3D dose to a moving CTV. In this study, we model respiratory motion as a sinusoidal function with an amplitude of 10 mm in the superior-inferior direction, a period of 5 seconds, and an initial phase of zero.

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An Estimation of Concentration of Asian Dust (PM10) Using WRF-SMOKE-CMAQ (MADRID) During Springtime in the Korean Peninsula (WRF-SMOKE-CMAQ(MADRID)을 이용한 한반도 봄철 황사(PM10)의 농도 추정)

  • Moon, Yun-Seob;Lim, Yun-Kyu;Lee, Kang-Yeol
    • Journal of the Korean earth science society
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    • v.32 no.3
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    • pp.276-293
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    • 2011
  • In this study a modeling system consisting of Weather Research and Forecasting (WRF), Sparse Matrix Operator Kernel Emissions (SMOKE), the Community Multiscale Air Quality (CMAQ) model, and the CMAQ-Model of Aerosol Dynamics, Reaction, Ionization, and Dissolution (MADRID) model has been applied to estimate enhancements of $PM_{10}$ during Asian dust events in Korea. In particular, 5 experimental formulas were applied to the WRF-SMOKE-CMAQ (MADRID) model to estimate Asian dust emissions from source locations for major Asian dust events in China and Mongolia: the US Environmental Protection Agency (EPA) model, the Goddard Global Ozone Chemistry Aerosol Radiation and Transport (GOCART) model, and the Dust Entrainment and Deposition (DEAD) model, as well as formulas by Park and In (2003), and Wang et al. (2000). According to the weather map, backward trajectory and satellite image analyses, Asian dust is generated by a strong downwind associated with the upper trough from a stagnation wave due to development of the upper jet stream, and transport of Asian dust to Korea shows up behind a surface front related to the cut-off low (known as comma type cloud) in satellite images. In the WRF-SMOKE-CMAQ modeling to estimate the PM10 concentration, Wang et al.'s experimental formula was depicted well in the temporal and spatial distribution of Asian dusts, and the GOCART model was low in mean bias errors and root mean square errors. Also, in the vertical profile analysis of Asian dusts using Wang et al's experimental formula, strong Asian dust with a concentration of more than $800\;{\mu}g/m^3$ for the period of March 31 to April 1, 2007 was transported under the boundary layer (about 1 km high), and weak Asian dust with a concentration of less than $400\;{\mu}g/m^3$ for the period of 16-17 March 2009 was transported above the boundary layer (about 1-3 km high). Furthermore, the difference between the CMAQ model and the CMAQ-MADRID model for the period of March 31 to April 1, 2007, in terms of PM10 concentration, was seen to be large in the East Asia area: the CMAQ-MADRID model showed the concentration to be about $25\;{\mu}g/m^3$ higher than the CMAQ model. In addition, the $PM_{10}$ concentration removed by the cloud liquid phase mechanism within the CMAQ-MADRID model was shown in the maximum $15\;{\mu}g/m^3$ in the Eastern Asia area.

Acoustic images of the submarine fan system of the northern Kumano Basin obtained during the experimental dives of the Deep Sea AUV URASHIMA (심해 자율무인잠수정 우라시마의 잠항시험에서 취득된 북 구마노 분지 해저 선상지 시스템의 음향 영상)

  • Kasaya, Takafumi;Kanamatsu, Toshiya;Sawa, Takao;Kinosita, Masataka;Tukioka, Satoshi;Yamamoto, Fujio
    • Geophysics and Geophysical Exploration
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    • v.14 no.1
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    • pp.80-87
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    • 2011
  • Autonomous underwater vehicles (AUVs) present the important advantage of being able to approach the seafloor more closely than surface vessel surveys can. To collect bathymetric data, bottom material information, and sub-surface images, multibeam echosounder, sidescan sonar (SSS) and subbottom profiler (SBP) equipment mounted on an AUV are powerful tools. The 3000m class AUV URASHIMA was developed by the Japan Agency for Marine-Earth Science and Technology (JAMSTEC). After finishing the engineering development and examination phase of a fuel-cell system used for the vehicle's power supply system, a renovated lithium-ion battery power system was installed in URASHIMA. The AUV was redeployed from its prior engineering tasks to scientific use. Various scientific instruments were loaded on the vehicle, and experimental dives for science-oriented missions conducted from 2006. During the experimental cruise of 2007, high-resolution acoustic images were obtained by SSS and SBP on the URASHIMA around the northern Kumano Basin off Japan's Kii Peninsula. The map of backscatter intensity data revealed many debris objects, and SBP images revealed the subsurface structure around the north-eastern end of our study area. These features suggest a structure related to the formation of the latest submarine fan. However, a strong reflection layer exists below ~20 ms below the seafloor in the south-western area, which we interpret as a denudation feature, now covered with younger surface sediments. We continue to improve the vehicle's performance, and expect that many fruitful results will be obtained using URASHIMA.

A Study on the Persons Enjoying the Landscape of Daegodea in Hamyang and Space Hegemony through Analysis of Poetry and Letters Carved on the Rocks (시문과 바위글씨로 본 함양 대고대(大孤臺)의 경관 향유자와 장소패권(場所覇權))

  • Rho, Jae-Hyun;Lee, Jung-Han
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.32 no.1
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    • pp.10-21
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    • 2014
  • This study focuses on the landscape of Daegodae(大孤臺), a prominent rock placed at the side of Namgae Stream in Hamyang, and the person who enjoy the landscape. Through the analysis of the letters such as names carved on the rocks based on ancient poetry and stone walls, the study examines the characteristics of the landscape and the space of Daegodae and the phase of hegemony to enjoy the landscape and space. The result of this study is as follow.2) There are 5 Seowon(書院: lecture halls) nearby Daegodae identified in the ancient map has 5 auditoriums nearby, and three-dimensional volume and eccentricity of the Daegodae is impressive. Daegodae, named by Noh Jin(1518~1578) in 16th century, was used in a variety of ways, including viewing, game, recreation, and meeting, by the staff of the lecture halls including Namgae Seowon(南溪書院), as a result of analyzing the ancient document Go-dae-il-Loc(孤臺日錄) written by Jung Kyung-Woon(鄭慶雲: 1556~?). The structure of Daegodae is that there is Chunggeunchung(淸近亭) on the rock face of the top and Sanangjae(山仰齋) to the west around the memorial stone for Yang Hee(梁喜: 1515~1581). The upper part of the foundation of Daegodae with 11m high and $10m^2$ wide to the east and west was widely used for lecturing and poetry reading. To the north and west of the foundation were the writing of Kim Jeong-Hee(金正喜: 1786~1856) with the words 'Seoksong Chusa(石松 秋史)' carved on the rock and the remains of a dead tree that is presumed to have been called as 'Seoksong'. They are the landscapes that further enhance the history and authenticity of this place. The two kinds of letters carved on the rock 'Daegodae Gaeeunseo(大高臺 介隱書)' and 'Mukheon JungGeunSang(鄭近相: 1893~1934)' were recorded each by Jung Jae-Gi(1811~1879) and his grandson Jung Geun-Sang, which are, as the outcome of exclusive space possession and space hegemony, the signatures indicating that they were the persons who enjoyed this place during the late Joseon and Japanese colonial era. In other words, Daegodae had some implied meaning of preoccupancy of the place as Gujolyangseonsengjangguso since the middle of Joseon, and the place was passed down as a buddhism lecturing and memorial venue called "Dungbukganghoiso Cheonryungjaeseonhyunjangguso" after going through the space hegemony of Jung Jae-Gi and Jung Geun-Sang during the late Joseon and Japanese colonial era each, Nevertheless, a number of letters carved on the rock identified also imply that 'Hadong Jung(河東鄭氏)' and 'Pungcheon Noh(豊川盧氏)' were those who enjoyed the landscape of Daegodae and the center of the space hegemony. The "letters carved on the rock of Daegudae" is another case of cultural landscape and traditional gardening space that serves as the representation of the will of enjoying the landscape in this place and the history of space hegemony.

Deformation structures of the Jurassic Ogcheon granite and the Honam Shearing, Ogcheon Area, Korea (옥천지역 쥬라기 옥천화강암의 변형구조와 호남전단운동)

  • Kang, Ji-Hoon
    • The Journal of the Petrological Society of Korea
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    • v.19 no.1
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    • pp.19-30
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    • 2010
  • The Jurassic Daebo Ogcheon granite is distributed in the Ogcheon area which is located in the central part of the Ogcheon Belt, Korea. This paper newly examines the timing of Honam shearing on the basis of the petrofabric researches on the deformation structures of the Ogcheon granite. The structural shape of Ogcheon granite is mainly characterized by a wedge shaped of E-W trend and an elongate shape of ENE trend in geological map and by contacts parallel to the regional S1 foliation in the host Ogcheon supergroup. It indicates that the pluton was permittedly emplaced after the S1 formation. The main deformation structures are marked by a solid-state tectonic foliation of N-S trend, which passes through the contact of the pluton, and by an aplitic dyke of E-W trend, and by sinistral, NW and E-W oriented shear zones on the eastern border of the pluton. The petrofabric study on the main deformation structures suggests that the tectonic foliation and the aplitic dyke were formed by the Honam dextral strike-slip shearing of (N)NE trend at ca. $500{\sim}450^{\circ}C$ deformation temperature, and that the sinistral shear zones could be induced by the dextral rotation of the pluton from its original site of intrusion, that is, by the shear strain which is due to sliding of the pluton past the host rocks. The history of emplacement and deformation of the Ogcheon granite and the previous results on the timing of Honam shearing would be newly established and reviewed as follows. (1) Early~Middle Jurassic(187~170 Ma); intrusion of syntectonic foliated granite related to Early Honam shearing, (2) Middle Jurassic(175~166 Ma); main magmatic period of Jurassic granitoids, the permitted emplacement of the Ogcheon granite, (3) Middle~Late Jurassic(168~152 Ma); main cooling period of Jurassic granitoids, the deformation of the Ogcheon granite related to Late Honam shearing. Thus, this study proposes that the Honam shear movement would occur two times at least during 187~152 Ma (ca. 35 Ma) through the intertectonic phase of 175~166 Ma.

Assessment of National Soil Loss and Potential Erosion Area using the Digital Detailed Soil Maps (수치 정밀토양도를 이용한 전국 토양 유실량의 평가 및 침식 위험지역의 분석)

  • Jung, Kang-Ho;Sonn, Yeon-Kyu;Hong, Seok-Young;Hur, Seung-Oh;Ha, Sang-Keon
    • Korean Journal of Soil Science and Fertilizer
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    • v.38 no.2
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    • pp.59-65
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    • 2005
  • This study was performed to estimate the soil loss on a national scale and grade regions with the potential risk of soil erosion. Universal soil loss equation (USLE) for rainfall and runoff erosivity factors (R), cover management factors (C) and support practice factors (P) and revised USLE for soil erodibility factors (K) and topographic factors (LS) were used. To estimate the soil loss, the whole nation was divided into 21,337 groups according to city county, soil phase and land use type. The R factors were high in the southern coast of Gyeongnam and Jeonnam and part of the western coast of Gyeonggi and low in the inland and eastern coast of Gyeongbuk. The K factors were higher in the regions located on the lower streams of rivers and the plain lands of the western coast of Chungnam and Jeonbuk. The average slope of upland areas in Pyeongchang-gun was the steepest of 30.1%. The foot-slope areas from the Taebaek Mountains to the Sobaek Mountains had steep uplands. Total soil loss of Korea was estimated as $50{\times}10^6Mg$ in 2004. The potential risk of soil erosion in upland was the severest in Gyeongnam and the amount of soil erosion was the greatest in Jeonnam. The regions in which annual soil loss was estimated over $50Mg\;ha^{-1}$ were graded as "the very severe" and their acreage was $168{\times}10^3ha$ in 2004. The soil erosion maps of city/county of Korea were made based on digital soil maps with 1:25,000 scale.

Geological Structures of the Hadong Northern Anorthosite Complex and its surrounding Area in the Jirisan Province, Yeongnam Massif, Korea (영남육괴 지리산지구에서 하동 북부 회장암복합체와 그 주변지역의 지질구조)

  • Lee, Deok-Seon;Kang, Ji-Hoon
    • The Journal of the Petrological Society of Korea
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    • v.21 no.3
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    • pp.287-307
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    • 2012
  • The study area, which is located in the southeastern part of the Jirisan province of the Yeongnam massif, Korea, consists mainly of the Precambrian Hadong northern anorthosite complex (HNAC) and the Jirisan metamorphic rock complex (JMRC) and the Mesozoic granitoids which intrude them. Its tectonic frame is built into NS trend, unlike the general NE-trending tectonic frame of Korean Peninsula. This paper researched the structural characteristics at each deformation phase to clarify the geological structures associated with the NS-trending tectonic frame which was built in the HNAC and JMRC. The result indicates that the geological structures of this area were formed at least through three phases of deformation. (1) The $D_1$ deformation formed the $F_1$ sheath or "A"-type folds in the HNAC and JMRC, and the $S_{0-1}$ composite foliation and the $S_1$ foliation and the $D_1$ ductile shear zone which are (sub)parallel to the axial plane of $F_1$ fold, and the $L_1$ stretching lineation which is parallel to the $F_1$ fold axis owing to the large-scale top-to-the SE shearing on the $S_0$ foliation. (2) The $D_2$ deformation (re)folded the $D_1$ structural elements under the EW-trending tectonic compression environment, and formed the NS-trending $F_2$ open, tight, isoclinal, intrafolial folds with the $S_{0-1-2}$ composite foliation and the $S_2$ foliation and the $D_2$ ductile shear zone with S-C-C' structure and the $L_2$ stretching lineation which is (sub)parallel to the axial plane of $F_2$ fold. The extensive $D_2$ ductile shear zone (Hadong shear zone) of NS trend was persistently developed along the eastern boundary of HNAC and JMRC which would be to the limb of $F_2$ fold on a geological map scale. The Hadong shear zone is no less than 1.4 km width, and was formed in the mylonitization process which produced the mylonitic structure and the stretching lineation with the reduction of grain size during the $F_2$ passive folding. (3) The $D_3$ deformation formed the EW-trending $F_3$ kink or open fold under the NS-trending tectonic compression environment and partially rearranged the NS-trending pre-$D_3$ structural elements into (E)NE or (W)NW direction. The regional trend of $D_1$ tectonic frame before the $D_2$ deformation would be NE-SW unlike the present, and the NS-trending tectonic frame in the HNAC and JMRC like the present was formed by the rearrangement of the $D_1$ tectonic frame owing to the $F_2$ active and passive folding. Based on the main intrusion age of (N)NE-trending basic dyke in the study area, these three deformation events are interpreted to have occurred before the Late Paleozoic.