• Title/Summary/Keyword: Phase II study

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Changes of Surface Electromyography on Frontalis Muscle during Electro-Acupuncture Stimulation of Abdomen or Legs - A Pilot Study for Clinical Approach to Autonomic Nervous System Changes - (복부 및 사지 부위의 전기침 자극이 전두근에서 측정한 SEMG 변화에 미치는 영향 - 자율신경계의 변화에 대한 임상적 접근을 위한 사전 연구 -)

  • Je, Jun-Tae;Choi, San-Ho;Shin, Sun-Ho;Lim, Jin-Young;Lee, Sang-Kwan
    • The Journal of Internal Korean Medicine
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    • v.33 no.1
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    • pp.14-25
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    • 2012
  • Objectives : To observe physiological changes during clinical acupuncture treatment. Methods : We recruited 40 healthy volunteers who had experienced an acupuncture treatment at least once within the past three years. The experimental group was divided into four groups according to the needling site and frequency of electrical stimulation. Sites consisted of abdomen and legs. Frequencies consisted of 100 Hz and 2 Hz. The procedures of experimental treatment consisted of seven phases, Resting I phase (Resting I), Needle insertion phase (Insertion), Maintenance of needle insertion I phase (Maintain I), Electrical stimulation phase (ES), Maintenance of needle insertion II phase (Maintain II), Needle removal phase (Removal) and Resting II phase (Resting II). We measured the surface electromygraphy (SEMG) through an electrode on the frontalis muscle during all phases consecutively. Results : When SEMGs of all seven phases were analyzed, they significantly increased or decreased according to phases. SEMGs of Insertion, Maintain I, ES and Maintain II phase significantly increased more than RestingI in abdomen and legs groups. SEMGs of the abdomen group were measured as being $4.78{\pm}0.74{\mu}V$ on Resting I, $16.48{\pm}3.97{\mu}V$ on Insertion, $46.31{\pm}10.56{\mu}V$ on Maintain I, $45.88{\pm}9.72{\mu}V$ on ES, $45.56{\pm}9.69{\mu}V$ on Maintain II, $18.76{\pm}3.05{\mu}V$ on Removal, and $3.75{\pm}0.65{\mu}V$ on Resting II. SEMGs of the legs group were measured as being $3.34{\pm}0.35{\mu}V$ on Resting I, $12.11{\pm}1.76{\mu}V$ on Insertion, $36.74{\pm}6.99{\mu}V$ on Maintain I, $33.57{\pm}6.30{\mu}V$ on ES, $32.66{\pm}6.03{\mu}V$ on Maintain II, $14.08{\pm}2.15{\mu}V$ on Removal, and $2.88{\pm}0.32{\mu}V$ on Resting II. Conclusions : SEMG changed differently according to processes of acupuncture. Electrical stimulation showed different change of SEMG. Thus, acupuncture treatment may change the status of the autonomic nervous system.

A Study on the PR shaped SQAM error rate with carrier phase error (PR Shape된 SQAM의 오율에 반송파위상오차가 미치는 영향에 대한 연구)

  • 박용우;이형재
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.9 no.1
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    • pp.11-17
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    • 1984
  • A study is presented showing the effect of carrier phase error on the error-rate of a (Class I, II, IV)PR shaped SQAM digital communication system. A simple upper bound on the probabilty of error as a function of phase error is derived and compared to one another. The results show that the three system can be used appropriately if carrier phase error is less than 3$^{\circ}$. However, if phase error is larger than 3, the PR class I is the best choice.

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Improvement of catheter-related outcomes after application of tunneled cuffed hemodialysis catheter insertion without fluoroscopy

  • Kang, Seok Hui;Do, Jun Young
    • Journal of Yeungnam Medical Science
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    • v.37 no.3
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    • pp.186-193
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    • 2020
  • Background: Non-tunneled catheters (NTCs) are used for hemodialysis (HD) in many centers in which fluoroscopy is not easily accessed despite high complication rates and conditions requiring long-term HD. Therefore, here we aimed to evaluate the superiority of catheter-related outcomes after the application of tunneled cuffed catheter (TCC) without fluoroscopy versus unconditioned NTC insertion. Methods: We divided the participants into two phases: those receiving NTCs between March 2010 and February 2011 (phase I), and those receiving TCCs or NTCs between March 2011 and February 2012 (phase II). Catheter survival, nurse satisfaction, and reasons for catheter removal were analyzed. Results: Two hundred and sixty patients in phase I and 300 patients in phase II were enrolled in this study. The success rate of TCC insertion was 99.2%. The catheter survival rate in phase I was 65.5% at 1 month, while that in phase II was 74.9% at 1 month (p=0.023). We compared catheter survival between TCCs and NTCs for all periods regardless of phase. The TCC survival rate was higher than the NTC survival rate (p<0.001). Catheter-associated problems led to catheter removal in 97 patients (26.6%) in phase I and 68 patients (18.5%) in phase II (p=0.009). Among 14 HD nurses, all reported being satisfied with manipulation during pre-/post-HD, manupulation during HD, and overall. Eleven HD nurses (78.6%) reported being satisfied with the workload. Conclusion: Compared with unconditional NTC insertion for HD, TCC insertion without fluoroscopy improved the overall catheter survival and nurse satisfaction rates.

Transportation and kinetic analysis of Zn(II) ions via MDLM system containing D2EHPA as carrier

  • Erden, Kadriye Esen;Donat, Ramazan
    • Membrane and Water Treatment
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    • v.9 no.1
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    • pp.23-31
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    • 2018
  • In this study, a new method called as multi-dropped liquid membrane (MDLM) which is more practical and more effective than other liquid membrane techniques is applied for transport of Zn(II) has been studied. HCl as the stripping solution and D2EHPA dissolved in kerosene as the membrane solution, has been examined. The effects of stripping solution concentration, carrier concentration, temperature and pH in the feed phase on the transport of Zn(II) have also been investigated. As a result, the optimum transport conditions of Zn(II) were obtained, i.e., the concentration of HCl solution was 0.25 M, the concentration of D2EHPA was $8{\times}10^{-3}M$, and pH value in the donor phase was 5.00. Under the optimum conditions, the transport percentage of Zn(II) was up to >99% during the transport time of 80 min when the initial concentration of Zn(II) was $120mgL^{-1}$. The activation energy is calculated as $5.30kcalmol^{-1}$. The value of calculated activation energy indicates that the process is diffusionally controlled by Zn(II) ions. The experiments have demonstrated that D2EHPA derivative is a good carrier for Zn(II) transport through MDLM in the study.

Effects of Cervical Exercise with Sling Program on Sleep Disturbance and Headache, Neck Disfunction in Torture of Survivor : Single Case Study (슬링을 이용한 경부관절 운동이 고문생존자의 수면장애, 두통, 경부 기능장애에 미치는 영향 : 단일사례연구)

  • Yu, Seonghun
    • Journal of The Korean Society of Integrative Medicine
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    • v.5 no.1
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    • pp.11-18
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    • 2017
  • Purpose : The purpose of this case study was to clinical effects of cervical exercise with sling program using on torture of survivor with sleep disturbance and Headache, neck disfunction. Methods : This study selects 1 subjects for 55 years old who were diagnosed with torture of survivor with sleep disturbance and headache. The Design is ABA of single-subject study design. Baseline(A) and TypeII Baseline(A : 6weeks) phases were received with musculoskeletal disease of prevention education, Intervention(B : 6weeks) phase provided with 65 minute exercise with sling program using in a session twice a week. In order to analyze the measure results of PSQI-K(korean version of the pittsburgh sleep quality index), VAS(visual analog scale), NDI(neck disability index), FABQ(fear-avoidance beliefs questionnaire) in torture of survivor during baseline, intervention and typeII baseline phase. Result : A significant differences in PSQI-K during baseline, intervention, typeII baseline. A significant differences in VAS during baseline, intervention, typeII baseline. A significant differences in NDI during baseline, intervention, typeII baseline. A significant differences in FABQ during baseline, intervention, typeII baseline. Conclusion : In conclusion, The intervention method to applied cervical exercise with sling program on torture of survivor effectively improve on sleep disturbance and neck function, headache.

Development of Working Tractor with Four-Type Wheel Steering System II(Development of Four-Type Wheel Steering System) (4방식 조향장치를 적용한 관리 작업차 개발 II(4방식 조향장치 개발))

  • Cho Hyun-Deog
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.14 no.3
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    • pp.81-86
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    • 2005
  • The agricultural working tractor of this study is equipped with 4 wheel driving system developed in study 1 and 4-type wheel steering system. The wheel steering system has four type of steering methods that are front wheel steering, rear wheel steering, 4 wheel steering with opposite phase, and 4 wheel steering with corresponding phase. This study introduces the hydraulic circuit of the 4-type wheel steering system and the construction of working tractor. Judging from the field test results of the developed working tractor, it is apparent that 4-type wheel steering system has many advantages when driving in a narrow corral.

A Study on the Retention Behavior of Co(II)-Dithiocarbamate Chelates in Reversed Phase-High Performance Liquid Chromatography (역상 액체크로마토그래피에서 Co(II)-Dithiocarbamate 킬레이트의 머무름 거동에 관한 연구)

  • Lee, Won;Kim, Eun-Kyung;Ann, Hye-Sook;Lee, Jung-Han
    • Analytical Science and Technology
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    • v.12 no.5
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    • pp.387-396
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    • 1999
  • The retention behavior of Cot(II)-dithiocarbamate(DTC) chelates in reversed phase high performance liquid chromatography was investigated. Enthalpy and entropy of chelates transfer from the mobile phase to the stationary phase were calculated from retention data using van't Hoff plots. The dependence of In k' on enthalpy was decreased with increasing organic solvent ratio on the mobile phase. The compensation temperatures(${\beta}$) calculated from the slope of $-{\Delta}H^0$ vs In k' were in the range of 756.3-888.5 K. From these results. it was found that the retention mechanism of DTC chelates was invariant under the various temperatures and was largely affected by the solvophobie effect. Liniear relationship between S index and log k' in emprical retention equation, $log\;k^{\prime}=log\;{k_w}^{\prime}-S_{\varphi}$ showed that S index was influenced mainly by the interaction between DTC chelates and the mobile phase.

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Nutrient Utilization and Compensatory Growth in Crossbred (Bos indicus×Bos taurus) Calves

  • Santra, A.;Pathak, N.N.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.8
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    • pp.1285-1291
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    • 1999
  • A feeding trial was carried out over 238 days to determine the effect of compensatory growth in crossbred calves having 166 kg body weight. Fifteen crossbred calves were divided into two groups of five calves (G1 group) and ten calves (G2 group) as per randomized block design. Growth study was conducted on the feeding of wheat straw based diet containing 60 and 30 percent concentrate supplying equal amount of protein in group G1 and G2 respectively for 119 days (phase - I). At the end of phase-I, calves of G2 group were subdivided in to two groups (G3 and G4). One sub group (G4) received 60% concentrate in their diet (during 120 to 238 days of experiment) while other subgroup G3 received 30% concentrate in their diet (phase-II). The calves of G1 group continued to receive the same diet as during phase-I experiment. Mean DM intake was significantly higher in calves fed high level of concentrate (in G1 and G4 groups), which resulted in significantly higher digestibility of all nutrients except NDF. Nitrogen balance was positive in all the groups and showed significant differences in phase-II (higher nitrogen retention in G4 group than G1 group). ME intake was significantly affected by the level of dietary concentrate, being higher in high concentrate fed group (G1 and G4 than G2 and G3 group). Higher daily body weight gain in the calves of G4 group during phase-II than in G1 and G3 groups was due to compensatory growth on shifting animals from low concentrate to high concentrate based ration. Average daily body weight gain was higher in phase-I than in the phase-II. Protein and energy intake per unit body weight gain were significantly lower in calves fed high concentrate diet.

Effects of Acori Graminei Rhizoma Aqua-acupunture Solution(AGRAS) on Induction of Cancer Chemopreventive Enzymes (석창포(石菖蒲) 약침액(藥鍼液)의 암(癌) 예방(豫防) 관련 효소 유도 효과)

  • Roh Dong-Il;Lim Jong-Kook
    • Korean Journal of Acupuncture
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    • v.19 no.2
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    • pp.51-56
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    • 2002
  • Induction of phase II enzymes such as quinone reductase (QR) and glutathione S-transferase (GST) is considered a major mechanism of protection against initiation of carcinogenesis. The present study was performed to evaluate the chemopreventive activity of Acori Graminei Rhizoma aqua-acupuncture solution (AGRAS) and Acori Graminei Rhizoma water-extracted solution (AGRWS) by measuring the induction of phase II enzymes. AGRAS and AGRWS are potent inducers of quinone reductase activity in murine hepatoma Hepa1c1c7 cells. The levels of GSH and GST was increased sightly with AGRAS and AGRWS. These results suggest that AGRAS and AGRWS may act as blocking agents against carcinogenesis by induction of phase II enzymes.

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Induction of Glutathione S-transferase and NAD(P)H:Quinone Reductase by Astragali Radix Aqua-acupuncture Solution (황기(黃耆) 약침액(藥鍼液)의 Glutathione S-transferase 와 NAD(P)H: Quinone Reductase 유도)

  • Ryu Jun-Seon;Lim Jong-Kook
    • Korean Journal of Acupuncture
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    • v.18 no.1
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    • pp.21-26
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    • 2001
  • Induction of phase II enzymes such as quinone reductase (QR) or glutathione S-transferase (GST) is considered a major mechanism of protection against initiation of carcingenesis. This study was desinged to investigate the potential of Astragali Radix Aqua-acupuncture Solution (ARAS) to induce phase II enzymes and glutathione (GSH) in murine hepatoma cells grown in microtiter plate wells. ARAS was potent inducers of QR activity. ARAS was induced about 2.6-fold at concentration of $5{\times}$. In addition, GST activity was increased with ARAS. GSH levels were increased about 1.2-fold with ARAS at concentration of $0.1{\times}$. These results suggested that ARAS may act as blocking agents against carcinogenesis by induction of phase II marker enzymes.

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