• The Korean Journal of Physiology and Pharmacology
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• v.6 no.1
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• pp.1-7
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• 2002

Congenital Long QT syndrome (LQTs) is a relatively rare pathologic disorder but results frequently in sudden cardiac death. Of the six LQTs that have been clinically described, five have been worked out for their genetic and biophysical profile. Most are generated by mutations which cause a loss of function in two delayed $K^+$ currents, $i_{Ks}\;and\;i_{Kr}.$ One syndrome is generated by mutations in the $Na^+$ channel which causes essentially a gain of function in the channel. Clinically the syndromes are characterized by slowed repolarization of the cardiac ventricular action potential and the occurrence of typical arrhythmias with undulating peaks in the electrocardiogram, called Torsade de Pointes. Arrhythmias are initiated by early or delayed afterdepolarizations and continue as reentry. Triggers for cardiac events are exercise (swimming; LQT1), emotion (arousal; LQT2) and rest/sleep (LQT3). ${\beta}-blockers$ have a high efficacy in the treatment of LQT1 and LQT2. In LQT3 their use is questionable. The study of congenital LQTsyndromes is a remarkable example of how basic and clinical science converge and take profit of each other's contribution.

• Tuberculosis and Respiratory Diseases
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• v.80 no.1
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• pp.11-20
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• 2017

Approximately one in four patients with chronic obstructive pulmonary disease (COPD) have asthmatic features consisting of wheezing, airway hyper-responsiveness or atopy. The Global initiative for Asthma/Globalinitiative for chronic Obstructive Lung Disease committee recently labelled these patients as having asthma-COPD overlap syndrome or ACOS. ACOS also encompasses patients with asthma, ${\geq}40$ years of age, who have been cigarette smokers (more than 5-10 pack years) or have had significant biomass exposure, and demonstrate persistent airflow limitation defined as a post-bronchodilator forced expiratory volume in 1 second ($FEV_1$)/forced vital capacity of <70%. Data over the past 30 years indicate that patients with ACOS have greater burden of symptoms including dyspnea and cough and show higher risk of COPD exacerbations and hospitalizations than those with pure COPD or pure asthma. Patients with ACOS also have increased risk of rapid $FEV_1$ decline and COPD mortality. Paradoxically, experimental evidence to support therapeutic decisions in ACOS patients is lacking because traditionally, patients with ACOS have been systematically excluded from therapeutic COPD and asthma trials to maintain homogeneity of the study population. In this study, we summarize the current understanding of ACOS, focusing on definitions, epidemiology and patient prognosis.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.7
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• pp.1756-1776
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• 2012

Wireless sensor networks (WSNs) are likely to be more prevalent as their cost-effectiveness improves. The spectrum of applications for WSNs spans multiple domains. In environmental sciences, in particular, they are on the way to become an essential technology for monitoring the natural environment and the dynamic behavior of transient physical phenomena over space. Existing sensor network query processors (SNQPs) have also demonstrated that in-network processing is an effective and efficient means of interaction with WSNs for performing queries over live data. Inspired by these findings, this paper investigates the question as to whether spatio-temporal and historical analysis can be carried over WSNs using distributed query-processing techniques. The emphasis of this work is on the spatial, temporal and historical aspects of sensed data, which are not adequately addressed in existing SNQPs. This paper surveys the novel approaches of storing the data and execution of spatio-temporal and historical queries. We introduce the challenges and opportunities of research in the field of in-network storage and in-network spatio-temporal query processing as well as illustrate the current status of research in this field. We also present new areas where the spatio-temporal and historical query processing can be of significant importance.

• Nutrition Research and Practice
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• v.8 no.5
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• pp.564-570
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• 2014

BACKGROUND/OBJECTIVES: Although the issues of singles' dietary style and quality of life are becoming important due to the increasing number of singles with economic power, little research has been conducted to date on singles' use of convenience food and quality of life in relation to their dietary style. Thus, the present study intends to provide basic data to improve the quality of life by determining the current status of the use of convenience food and explicating its relationship with quality of life through analyzing the dietary lifestyles of the singles. SUBJECTS/METHODS: The targets of this study were singles, identified as adults between the ages of 25 and 54, living alone, either legally or in actuality having no partner. A statistical analysis of 208 surveys from Seoul, respectively, was conducted using SPSS12.0 for Windows and SEM using AMOS 5.0 statistics package. RESULTS: The convenience-oriented was shown to have a significant positive effect on convenience food satisfaction. HMR satisfaction was found to have a significant effect on positive psychological satisfaction and the convenience-oriented was found to have a significant negative effect on all aspects of quality of life satisfaction. CONCLUSIONS: There must be persistent development of food industries considering the distinctive characteristics of the lives of singles in order to satisfy their needs and improve the quality of their lives.

• The Journal of the Korea Contents Association
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• v.9 no.1
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• pp.177-186
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• 2009

Virtual world is persistent 3D(2D) space through computers which supports real-time interaction. Children's virtual worlds are for children below 15. Its educational benefits are: practical experience, cooperation possibility, experience sharing, and optimized environment. Moreover, interesting factors from games can enhance the educational efficiency of virtual worlds. In order to intensify the educational efficiency, goal, motivation, relationship and advice has to be considered as well. Based upon those factors, the result of analysis of current virtual worlds shows that they have clear goal. contextualization of task and appropriate reinforcement. However, for future prosperity, continuous effort for expansion of readiness, social persuasion, scaffolding are needed.

• 한국초전도학회:학술대회논문집
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• v.9
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• pp.373-377
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• 1999

HTS magnet operated at 20${\sim}$40 K was fabricated using three pieces of 100 m Bi-2223 high temperature superconductors fabricated by powder-in-tube process. It was composed of 6 double pancakes with 75 ID. and 113 OD. connected by lab splice. Coil I$_c$ of each DP.(double pancake) obtained for a 140 turn, fabricated using react and wind procedure was 6${\sim}$8 A at 77 K, self field. The maximum field was measured 0.06 T at lop = 5 A, 77 K. The joint resistance due to lap splice of HTS tapes affect badly to operate HTS magnet with persistent current mode, total effective magnet resistance included lap splice was 55 ${\mu}$ ${\omega}$ at 77 K.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8085-8091
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• 2016

Human papillomavirus is a virus that is distributed worldwide, and persistent infection with high-risk genotypes (HR-HPV) is considered the most important factor for the development of squamous cell cervical carcinoma (SCC). However, by itself, it is not sufficient, and other factors may contribute to the onset and progression of lesions. For example, infection with other sexually transmitted diseases such as human immunodeficiency virus (HIV) may be a factor. Previous studies have shown the relationship between HPV infection and SCC development among HIV-infected women in many regions of the world, with great emphasis on low- and middle-income countries (LMICs). Brazil is considered a LMIC and has great disparities across different regions. The purpose of this review was to highlight the current knowledge about HPV infection and cervical abnormalities in HIV+ women in Brazil because this country is an ideal setting to evaluate HIV impact on SCC development and serves as model of LMICs and low-resource settings.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.59
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• pp.113-135
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• 2013

Piracy has been an ongoing and serious problem in international shipping industry. Somalia is often in the news these days. Somalia has been in a state of unrest for more than two centuries. In recent times, the situation has remained unstable. The persistent unrest is the major driver behind the piracy epidemic in Somalia waters. By the MIA 1906, s.78(1), the expenses in order to be recoverable must have been "properly incurred". The underwriter is also liable in certain circumstances for expenses incurred by the assured in an attempt to avert or diminish loss covered by the policy, under provisions. This class of expenditure is commonly referred to as sue and labour expenses, or suing and labouring expenses; less commonly, as particular charges. The standard marine policy(the S.G.Form) contained what was invariably called the sue and labour clause, which has been replaced in the current Institute Clauses by the "Duty of Assured(Sue and Labour)" Clause in the Hull Clauses, and the "Duty of Assured" Clause, headed "Minimizing losses", in the Cargo Clauses. Sue and labour charges are not confined to expenditure on the part of the assured and his agents, but can include quantified loss consequent upon a sacrifice properly and reasonably made to avert or minimize an insured loss.

• Lingua Humanitatis
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• v.2 no.1
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• pp.43-74
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• 2002

This paper examines the concept of "tradition" for Indigenous Peoples as a construct of reality developed through the lens of Western scholarship and American Indian perspectives. The resulting notions of American Indian tradition constructed by a Western point of view, has been incorporated into the thinking of Western peoples as well as those of American Indians. Possible reasons for this include the lasting effects of colonialism and current mass media and the description of cultural "others" through the Western sciences of Anthropology and Musicology. A definition of what is valid or important in defining "traditional culture" for members of an Indigenous community may utilize significantly different measures than those of Western scholars. In order to illustrate this, the author uses two treatises focusing on the Indigenous American Indian cultures of communities in Eastern North America incorporating Indigenous points of view. One of these two books provides a focus on connections between language and culture and the other on ethnomusicology. From both of these perspectives, traditional identity is seen as continuing in the present day through persistent perceptions of reality, linked to community social performance. These perceptions and their accompanying indexes to tradition are still present despite the disappearance of or frequent changes in the surface forms of both language and manufactured cultural items. The emphasis on "legitimate" or "real" tradition is tied to performance within an ongoing cultural community rather than to Western constructions of what is real found in past descriptions of cultures. An alternative view of "valid" tradition and its relationship to Indigenous identity, needs to incorporate Indigenous perspectives rather than depend on constructions developed using non-Indigenous Western frameworks.

• The Journal of Information Systems
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• v.27 no.1
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• pp.1-20
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• 2018

Purpose The purpose of this study is to identify the determinants of non-use and the dynamic nature of non-use by the qualitative research methodology, grounded theory methodology, as part of identifying the nature of non-use. Design/methodology/approach We applied the grounded theory methodology to a total of 23 college students, including non-users who are not currently using them, users with low intention to use them, and users with high intention to use. We extracted the codes related to the use and proposed the non-use dynamics conversion process based on the coding results. Findings First, the use of information technology can also promote the frequency of use, but can also lead to the use of negative attitudes which would fall in the state of non-use. Second, the user may have both positive and negative attitudes toward the current information technology. Third, if usage is dominated by habits, it is not so easy to change persistent use into an unused state. Fourth, factors that determine the use of specific information technology can be a factor in determining nonuse. This study has contributed to understand the essence of non - use as well as the nature of use, overcoming limitations of quantitative research approach and confirming possibility of grounded theory method in information system research.