• 한국발생생물학회지:발생과생식
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• 제7권2호
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• pp.69-80
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• 2003

대량의 발생 유전학적 연구가 가능한 척추동물로서 최근 제브라피쉬가 새로운 동물모델로 급부상하고 있다 다양한 형태의 돌연변이들로부터 새로운 유전자들이 발굴되어지고 있으며, 인간 유전체의 기능 분석 수단으로 활용되어지고 있다. 신경계의 형성과 분화에 이상이 있는 hendless와 mind bomb이라는 두 가지 돌연변이주에서 positional cloning에 의한 원인 유전자의 발굴과 기능 분석의 예로써 현재 제브라피쉬의 연구 현황을 살펴보고자 한다. headless의 원인 유전자로 Tcf-3가 밝혀졌으며, 초기 발생단계에서 Wnt 신호전달이 두뇌의 형태형성과 영역 결정에서 핵심적 역할을 하고 있다는 사실이 밝혀졌다. mind bomb에서의 비정상적인 신경세포의 운명 결정은 lateral inhibition과 Notch 신호전달의 결함에 의한 것이고, 그 원인 유전자는 Notch ligand인 Delta에 결합하는 새로운 ubiquitin E3 ligase로 밝혀졌다. 이러한 돌연변이를 통한 연구는 현재 인간 질환모델의 개발이라는 방향으로 확대되고 있다.

• 한국중재학회지:중재연구
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• 제25권3호
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• pp.59-90
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• 2015

Since 1855, the federal courts of the United States have been empowered to assist in the gathering of evidence for use before foreign tribunals. Today, the source of that authority is 28 U.S.C. ${\S}1782$ which permits the courts to order a person "to give [ ] testimony... or to produce a document ... for use in a proceeding in a foreign or international tribunal${\cdots}$ ." It was generally assumed, until the United States Supreme Court's decision of Intel Corp. v. Advanced Micro Devices, Inc. in 2004, that arbitration tribunals were not "foreign tribunals" for purposes of 28 U.S.C. ${\S}1782$. While the issue in Intel did not involve an arbitration tribunal, a statement by the Supreme Court in dicta has called into question the exact parameters of the words "foreign tribunal," resulting in a split of opinion among the federal courts of the United States. This article explores the legislative history of 28 U.S.C. ${\S}1782$, examines the United States Supreme Court decision in Intel, and discusses the split among the courts of the United States regarding the interpretation of "foreign tribunal." The article further surveys emerging issues: is an arbitration tribunal in a case involving foreign parties and seated in the United States a "foreign tribunal"; does agreeing to the use of the IBA Rules on the Taking of Evidence in International Arbitration circumscribe the use of 28 U.S.C. ${\S}1782$; can a party be ordered to produce documents located outside the United States; and is there a role for judicial estoppel in determining whether an application pursuant to 28 U.S.C. ${\S}1782$ should be granted?

• 한국중재학회지:중재연구
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• 제19권2호
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• pp.3-26
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• 2009

This paper is to research on the role of party autonomy in the decision of applicable law for the arbitral proceeding, arbitral award and arbitration agreement, in the decision of the place of arbitration, in the composition of arbitration tribunal, and the choice of arbitral proceedings. The principle of party autonomy is fundamental to arbitration in general and to international arbitration in particular. Generally the tenn of party autonomy is used as the autonomy of the parties to decide all aspects of an arbitration procedure subject only to certain limitations of mandatory law. Party autonomy permits the parties to a commercial arbitration to choose the laws and make the rules which govern the arbitral proceedings. Party autonomy allows the parties freedom to choose the applicable laws for the arbitral proceeding and the place of arbitration. Party autonomy is recognized in relation to the choice of law for the merits of the dispute as well as for the arbitration agreement and the arbitration procedure. On the basis of the recognition of party autonomy in international treaties, national legislation and court decisions, arbitral practice has generally accepted and enforced party autonomy both regarding the procedure and the applicable substantive law. All modern institutional rules of arbitration follow that line. Today it is recognized by national legislators all over the world to the effect that the jurisdiction of national courts can be excluded by arbitration agreement and that the parties may choose the law applicable to arbitral proceedings. Limits on party autonomy are imposed by mandatory provisions of international or national law or of institutional arbitration rules regarding the procedure. Mandatory laws at the place of the arbitration or under any procedural law chosen by the parties may restrict party autonomy. These mandatory laws usually take the form of public policy considerations in the arbitration. Limitations on party autonomy have been reduced more and more, and the trend of modern national as well as international legislation on arbitration leans clearly in the direction of a maximum of party autonomy.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(5)
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• pp.21-24
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• 2002

There has been a growing need for interaction between human operator and a remote system to perform a complex task in an unpredictable environment and to operate an important work at a remote distance. The interaction becomes an important parameter in the teleautonomous operation because it permits the operator to control the system at remote distance. As the environmental uncertainties to be applied are getting increased, so is the difference between the plan of the operator and the execution of the system increased. Since the operator may be difficult to know the latest information from frequently changing environment due to time-varying delays, remote system may be hard to control in accordance with the operators command. Interactive Teleautonomous Control System (ITCS) is an approach based on interactions at these environments. The ITCS can be regarded as a control system using the transmitted a system's intnetion. The interactive teleautonomous control does not mean the interaction from operators point of view only considering feedback environmental information and forward simulation but an interaction between the operator and the system that transmits or receives intentions. The proposed ITCS is based on the intention communication that transmits their intentions to each other. The ITCS can correctly control the system in accordance with the operator's intention. Using the intention communication, a system intention is helpful to the operator. In the interactive teleautonomous control, the intention communication has to be provided by the interaction between the operator and the system.

• Journal of Electrical Engineering and Technology
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• 제11권3호
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• pp.609-617
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• 2016

Belt-driven Starter Generator (BSG) differs from other mild hybrid systems as the crankshaft of vehicle are not run off. Motor permits a low-cost method of adding mild hybrid capabilities such as start-stop, power assist, and mild levels of regenerative braking. Wound rotor synchronous motor (WRSM) could be adopted in BSG system for HEV e-Assisted application instead of the interior permanent magnet synchronous motor (IPMSM). In practice, adequate torque is indispensable for starter assist system, and energy conversion should be taken into account for the HEV or EV as well. Particularly, flux weakening control is possible to realize by adjusting both direct axis components of current and field current in WRSM. Accordingly, this paper present an off-line current acquisition algorithm that can reasonably combine the stator and field current to acquire the maximum torque, meanwhile the energy conversion is taken into consideration by losses. Besides, on account of inductance influence by non-uniform air gap around rotor, nonlinear inductances and armature flux linkage against current variation are proposed to guarantee the results closer to reality. A computer-aided method for proposed algorithm are present and results are given in form of the Look-up table (LUT). The experiment shows the validity of algorithm.

• 대한치과보철학회지
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• 제28권1호
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• pp.43-61
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• 1990

The laser reflexion method is a new technique which permits precise contactless measurement and observation of tooth mobility as well as tooth movement. The purposes of this study were to clarify the reliability of the laser reflexion method in clinical application and to measure the abutment tooth movement according to clasp design. This study was designed to determine 1) How much a bending movement of the impression plate stand affects the position of the reflexion pattern and how precise the patient bites into plate 2) Which clasp design causes greater movement of the abutment tooth. Under medium and maximum bite forces, tests were performed on central loading position which was 13mm distal to terminal abutment tooth of distal extension removable partial denture. The movement in the mesiodistal and buccolingual directions was measured. The Duncan's New Multiple-Range test was used to compare the means for the four castings under each direction-load combination; and the paired sample t-test was for medium and maximum bite forces. From this experiment, the following results were obtained. 1. The Roach clasp, the combination clasp, the RPI clasp, and the Akers clasp did not significantly differ in their effects on buccolingual movement of the abutment tooth. 2. The direction of abutment tooth movement was not significantly altered by clasp design and all abutment tooth movements were oriented distobuccally. 3. Under medium bite force, the Akers clasp caused greater distal movement of the abutment tooth than did the combination clasp and the RPI clasp. Under maximum bite force, the Akers clasp caused greater distal movement of the abutment tooth than did the RPI clasp. 4. The testing apparatus and procedures used in this study(laser reflexion method) proved to be reliable in clinical application.

• Earthquakes and Structures
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• 제13권3호
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• pp.255-265
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• 2017

In this paper, an efficient shear deformation theory is developed for wave propagation analysis in a functionally graded beam. More particularly, porosities that may occur in Functionally Graded Materials (FGMs) during their manufacture are considered. The proposed shear deformation theory is efficient method because it permits us to show the effect of both bending and shear components and this is carried out by dividing the transverse displacement into the bending and shear parts. Material properties are assumed graded in the thickness direction according to a simple power law distribution in terms of the volume fractions of the constituents; but the rule of mixture is modified to describe and approximate material properties of the functionally graded beams with porosity phases. The governing equations of the wave propagation in the functionally graded beam are derived by employing the Hamilton's principle. The analytical dispersion relation of the functionally graded beam is obtained by solving an eigenvalue problem. The effects of the volume fraction distributions, the depth of beam, the number of wave and the porosity on wave propagation in functionally graded beam are discussed in details. It can be concluded that the present theory is not only accurate but also simple in predicting the wave propagation characteristics in the functionally graded beam.

• Investigative Magnetic Resonance Imaging
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• 제21권1호
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• pp.20-27
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• 2017

Purpose: To evaluate quantification results of single breath-hold (SBH) magnetic resonance (MR) cine imaging compared to results of conventional multiple breath-hold (MBH) technique for left ventricular (LV) function in patients with cardiac arrhythmia. Materials and Methods: MR images of patients with arrhythmia who underwent MBH and SBH cine imaging at the same time on a 1.5T MR scanner were retrospectively reviewed. Both SBH and MBH cine imaging were performed with balanced steady state free precession. SBH scans were acquired using temporal parallel acquisition technique (TPAT). Fifty patients ($65.4{\pm}12.3years$, 72% men) were included. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), myocardial mass, and LV regional wall motion were evaluated. Results: EF, myocardial mass, and regional wall motion were not significantly different between SBH and MBH acquisition techniques (all P-values > 0.05). EDV, ESV, and SV were significant difference between the two techniques. These parameters for SBH cine imaging with TPAT tended to lower than those in MBH. EF and myocardial mass of SBH cine imaging with TPAT showed good correlation with values of MBH cine imaging in Passing-Bablok regression charts and Bland-Altman plots. However, SBH imaging required significantly shorter acquisition time than MBH cine imaging ($15{\pm}7sec$ vs. $293{\pm}104sec$, P < 0.001). Conclusion: SBH cine imaging with TPAT permits shorter acquisition time with assessment results of global and regional LV function comparable to those with MBH cine imaging in patients with arrhythmia.

• 한국응용과학기술학회지
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• 제29권1호
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• pp.159-173
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• 2012

UV 경화기술은 라디칼 경화와 양이온 경화로서 크게 2 종류로 분류할 수 있다. 이 기술은 플라스틱과 금속간의 여러 기재에 대한 기능성을 개선하기 위해서 표면처리기술에 주로 초점이 맞추어져 왔다. 반면에, Electron beam 기술은 새로운 기능성 재료들을 창출하기 위해 중합공정뿐만 아니라 가교반응들을 다루었다. 이들 두 기술들은 종래의 열경화성 코팅과 비교할 때, 에너지이용 효율과 환경 친화적이어서, 건조와 경화 공정으로 부터 배출되는 탄산가스와 휘발성 유기물을 대폭 감소시킨다. 이 논문에서는 UV 경화 코팅에서 흔히 사용되는 라디칼 경화기술과, 최근의 있는 양이온 경화와 관련된 기술을 다룬 리뷰 논문이다.

• Preventive Nutrition and Food Science
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• 제11권4호
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• pp.348-357
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• 2006

Nano is a unit that designates a billionth; accordingly nanotechnology could be described as the study and applications of the unique characteristics and phenomena of nanometer size materials. Applications of nanotechnology fall into two categories (one is top-down and the other is bottom-up). Currently, most products are the results of the top-down approach. Nanofoods have distinct functional characteristics stemming from the size, mass, chemical combinations, electrolytic features, magnetic properties of food sources at the nano level and which can be applied for safe absorption and delivery into the body. The greatest advantage of nanofood is that it permits the efficient use of small quantities of nutritional elements by increasing digestive absorption ability and by delivering natural elements without any change in their original characteristics. On the other hand, there are still unsolved problems, such as questions about safety and introduction of harmful material. The demand for new commercial food products is increasing, and commercial food producers are gradually combining nanotechnology and traditional food preparation methods. Nanofoods will improve our eating habits remarkably in the future. Tomorrow we will design nanofoods by shaping molecules and atoms. It will have a big impact on the food and food-processing industries. The future belongs to new products and new processes with the goals of customizing and personalizing consumer products. Nanotechnology is expected to be applied to not only foods themselves, but also to food packaging, production, safety, processing and storage. Also, it is believed that nanotechnology will be applied tracking finished products back to production facilities and even to specific processing equipment in those facilities. The aim of this study is the introduction of technology, applications, products, markets, R&D, and perspectives of nanofoods in the food industry.