• Title/Summary/Keyword: Permits

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Multispectral intravital microscopy for simultaneous bright-field and fluorescence imaging of the microvasculature

  • Barry G. H. Janssen;Mohamadreza Najiminaini;Yan Min Zhang;Parsa Omidi;Jeffrey J. L. Carson
    • Applied Microscopy
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    • v.51
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    • pp.12.1-12.12
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    • 2021
  • Intravital video microscopy permits the observation of microcirculatory blood flow. This often requires fluorescent probes to visualize structures and dynamic processes that cannot be observed with conventional bright-field microscopy. Conventional light microscopes do not allow for simultaneous bright-field and fluorescent imaging. Moreover, in conventional microscopes, only one type of fluorescent label can be observed. This study introduces multispectral intravital video microscopy, which combines bright-field and fluorescence microscopy in a standard light microscope. The technique enables simultaneous real-time observation of fluorescently-labeled structures in relation to their direct physical surroundings. The advancement provides context for the orientation, movement, and function of labeled structures in the microcirculation.

A Cost-Benefit Analysis of Emissions Reduction (배기(排氣)가스 배출억제(排出抑制)의 비용(費用)-수익분석(收益分析))

  • Lee, Hong-gue
    • KDI Journal of Economic Policy
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    • v.14 no.1
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    • pp.61-87
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    • 1992
  • Reducing the level of greenhouse gas emissions is necessary to mitigate global warming. One of the most feasible methods to reduce emissions would be to conserve energy and substitute fossil fuels. Yet reducing emissions entails huge financial costs, so it is advisable to employ cost-effective economic instruments such as a carbon tax or tradeable emissions permits. Assuming that the proper economic tools will be used in the future, we calculated the optimal level of emissions reduction for Korea. We applied to our cost-benefit analysis Nordhaus' scenario regarding the economic damage from a $3^{\circ}C$ rise in global temperatures, which is the calculated result when the greenhouse gas level doubles. The result of our analysis based on the 1990 data indicates that the optimal level of emissions reduction ranges from 2% to 15 % of current emissions depending on the value of damage parameters. We also found that the amount of emissions must be reduced will increase if action is postponed, when the development of climate engineering technology or more efficient use of energy is expected. In addition, we discussed the advantages and disadvantages of the economic instruments available to implement emissions reduction. Tradeable permits and carbon tax are equivalent in their cost-effectiveness, but have different implications in practice.

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Crack and Time Effect on Chloride Diffusion Coefficient in Nuclear Power Plant Concrete with 1 Year Curing Period (1년 양생된 고강도 원전 콘크리트의 염화물 확산에 대한 균열 및 시간효과)

  • Chun, Ju-Hyun;Ryu, Hwa-Sung;Yoon, Yong-Sik;Kwon, Seung-Jun
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.21 no.6
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    • pp.83-90
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    • 2017
  • Concrete structure for nuclear power plant is mass concrete structure with large wall depth and easily permits cracking in early age due to hydration heat and drying shrinkage. It always needs cooling water so that usually located near to sea shore. The crack on concrete surface permits rapid chloride intrusion and also causes more rapid corrosion in the steel. In the study, the effect of age and crack width on chloride diffusion is evaluated for the concrete for nuclear power plant with 6000 psi strength. For the work, various crack widths with 0.0~1.4 mm are induced and accelerated diffusion test is performed for concrete with 56 days, 180days, and 365 days. With increasing crack width over 1.0mm, diffusion coefficient is enlarged to 2.7~3.1 times and significant reduction of diffusion is evaluated due to age effect. Furthermore, apparent diffusion coefficient and surface chloride content are evaluated for the concrete with various crack width exposed to atmospheric zone with salt spraying at the age of 180 days. The results are also analyzed with those from accelerated diffusion test.

Application of Bender Elements in Consolidation, Tomography, and Liquefaction Tests (압밀, 토모그래피, 액상화시험에서 벤더엘리먼트의 적용)

  • Lee, Jong-Sub;Lee, Chang-Ho
    • Journal of the Korean Geotechnical Society
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    • v.22 no.8
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    • pp.43-54
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    • 2006
  • The scope of this paper covers the applications of bender element tests in consolidation, tomography, and liquefaction. Loading and unloading time during consolidation are evaluated based on shear wave velocity. As S-wave velocity is dependent on effective stress, the loading step may be determined. However, cautions are required due to the different mechanism between the settlement and effective stress criteria. The stress history may be evaluated because the S-wave shows the cement controlled regime and stress controlled regimes. A fixed frame complemented with bender elements permits S-wave tomography The tomography system is tested at low confinement within a true triaxial cell. Results show that shear wave velocity tomography permits monitoring changes in the velocity field which is related to the average effective stress. To monitor the liquefaction phenomenon, S-wave trans-illumination is implemented with a high repetition rate to provide detailed information on the evolution of shear stiffness during liquefaction. The evolution of shear wave propagation velocity and attenuation parallel the time-history of excess pore pressure during liquefaction. Applications discussed in this paper show that bender elements can be a very effective tool for the detection of shear waves in the laboratory.

The Current State of Intended Equipment for Heating in Medical Use Based on Domestic Licensed Medical Devices (국내 인·허가 온열의료기기 기술 현황 조사 및 분석)

  • Su-Ran Lim;Jung-Hwan Park;Ji-Yeun Park;Song-Yi Kim
    • Korean Journal of Acupuncture
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    • v.40 no.4
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    • pp.156-168
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    • 2023
  • Objectives : This study aimed to determine the status of thermal stimulation devices approved in Korea for medical applications over the past 10 years, and based on this, to obtain insight for future thermal treatment in Korean medical institutions. Methods : We searched the item classification list entitled "Regulations on Medical Device Items and Rating by Item" from the Ministry of Food and Drug Safety Notice No. 2021-24, 2021 (Enforced March 19, 2021; www.mfds.go.kr) for individually licensed heaters using the terms "heat" and "heating". Results : We identified 17 items of thermal stimulation product group, of which 1,308 devices were licensed by February 4, 2022, and 53.2% of them (n=696) were devices with valid permits for distribution in Korea. Among the licensed devices, heating pad systems under/overlay (electric, home use) were approved the most, but combinational stimulator (for medical use, home use; Grade 2) accounted for the highest percentage among the current valid permission. Moxibustion apparatuses were licensed separately for electrical use and non-electrical use, and occupied a low percentage of the total devices. We analyzed 307 devices that were accompanied by technical documents and found that the heat sources were wires in 145 (47.2%), infrared rays in 44 (14.3%) and ultrasonic waves in 42 (13.7%) devices. Most (83.1%) devices were used for pain relief, while other applications included beauty, cancer treatment, maintenance of infant body temperature, and healing fractures. Conclusions : Thermal stimulation devices accounted for about 0.9% of all medical devices, and among them, combinational stimulators and heating pad systems under/overlay had the most valid permits. Thermal stimulation devices using heating wires and infrared rays were the most prevalent, and most were used to relieve pain. In order to develop a range of thermal stimulation devices that can be utilized in Korean medical institutions, it is imperative that they have potential applications beyond pain management, addressing various medical purposes. To achieve this, foundational research is necessary to effectively apply diverse heat sources based on medical objectives.

Selection of Evaluation Metrics for Grading Autonomous Driving Car Judgment Abilities Based on Driving Simulator (드라이빙 시뮬레이터 기반 자율주행차 판단능력 등급화를 위한 평가지표 선정)

  • Oh, Min Jong;Jin, Eun Ju;Han, Mi Seon;Park, Je Jin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.44 no.1
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    • pp.63-73
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    • 2024
  • Autonomous vehicles at Levels 3 to 5, currently under global research and development, seek to replace the driver's perception, judgment, and control processes with various sensors integrated into the vehicle. This integration enables artificial intelligence to autonomously perform the majority of driving tasks. However, autonomous vehicles currently obtain temporary driving permits, allowing them to operate on roads if they meet minimum criteria for autonomous judgment abilities set by individual countries. When autonomous vehicles become more widespread in the future, it is anticipated that buyers may not have high confidence in the ability of these vehicles to avoid hazardous situations due to the limitations of temporary driving permits. In this study, we propose a method for grading the judgment abilities of autonomous vehicles based on a driving simulator experiment comparing and evaluating drivers' abilities to avoid hazardous situations. The goal is to derive evaluation criteria that allow for grading based on specific scenarios and to propose a framework for grading autonomous vehicles. Thirty adults (25 males and 5 females) participated in the driving simulator experiment. The analysis of the experimental results involved K-means cluster analysis and independent sample t-tests, confirming the possibility of classifying the judgment abilities of autonomous vehicles and the statistical significance of such classifications. Enhancing confidence in the risk-avoidance capabilities of autonomous vehicles in future hazardous situations could be a significant contribution of this research.

Analysis of Keywords in national river occupancy permits by region using text mining and network theory (텍스트 마이닝과 네트워크 이론을 활용한 권역별 국가하천 점용허가 키워드 분석)

  • Seong Yun Jeong
    • Smart Media Journal
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    • v.12 no.11
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    • pp.185-197
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    • 2023
  • This study was conducted using text mining and network theory to extract useful information for application for occupancy and performance of permit tasks contained in the permit contents from the permit register, which is used only for the simple purpose of recording occupancy permit information. Based on text mining, we analyzed and compared the frequency of vocabulary occurrence and topic modeling in five regions, including Seoul, Gyeonggi, Gyeongsang, Jeolla, Chungcheong, and Gangwon, as well as normalization processes such as stopword removal and morpheme analysis. By applying four types of centrality algorithms, including stage, proximity, mediation, and eigenvector, which are widely used in network theory, we looked at keywords that are in a central position or act as an intermediary in the network. Through a comprehensive analysis of vocabulary appearance frequency, topic modeling, and network centrality, it was found that the 'installation' keyword was the most influential in all regions. This is believed to be the result of the Ministry of Environment's permit management office issuing many permits for constructing facilities or installing structures. In addition, it was found that keywords related to road facilities, flood control facilities, underground facilities, power/communication facilities, sports/park facilities, etc. were at a central position or played a role as an intermediary in topic modeling and networks. Most of the keywords appeared to have a Zipf's law statistical distribution with low frequency of occurrence and low distribution ratio.

XED: Model-based XML Editor Generator for Data-Centric XML Documents (XED: 데이타 중심 XML문서를 위한 모델 기반의 XML 편집기 생성 도구)

  • 최종명;유재우
    • Journal of KIISE:Software and Applications
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    • v.30 no.10
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    • pp.894-903
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    • 2003
  • Though XML is widely used, it is still hard for end users to write XML documents. A lot of XML documents are data-centric documents which have formal data format. Even novices can easily write the data-centric XML documents if they use form-based GUIs. In this paper, we introduce a new method for generating form-based XML editor for data-centric XML documents automatically and an XML editor generator called XED. The DTD consists of sequence, choice, and repetition, and this structure can be represented with Document Decomposition Graph(DDG). XED allows users to generate an XML editor by applying the presentation rules to DDG. It also permits users to modify generated editor through changing editor`s GUI properties with direct manipulation.

A Synthesis of Combinational Logic with TANT Networks (조합논리함수의 TANT회로에 의한 합성)

  • 고경식
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.5 no.4
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    • pp.1-8
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    • 1968
  • A TANT network is a three-level network composed solely of NAND gates having only true(i.e. uncomplemented) inputs. The paper presents a technique for finding for any given Boolean function a least-cost TANT network. The first step of the technique is to determine essential prime implicants(EPI) by Quine-McCluskey procedure or other methods and generate prime implicants(PI) hving the same head as any one of EPI by consensus operation. The second step is to select common factors among the usable tail factors. The selcetion phase is analogous to the use of C-C table. The last step is to minimize inputs by deleting the redundant PI. the technique permits hand solution of typical five-and six-variable problems.

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Simulation of High-current Vacuum Arcs: (I)Axial Magnetic Field (진공차단부 대전류 아크 해석: (I)축방향 자기장)

  • Hwang, Jung-Hoon;Lee, Jong-Chul;Choi, Myung-Jun;Kwon, Jung-Lock;Kim, Youn-Jea
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.2500-2505
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    • 2007
  • The vacuum interrupter (VI) is used for medium-voltage switching circuits due to its abilities and advantages as a compact and environmental friendly circuit breaker. In general, the application of a sufficiently strong axial magnetic field (AMF) permits the arc to be maintained in a diffused mode to a high-current vacuum arc. A full understanding of the vacuum arc physics is very important since it can aid to improve the performance of vacuum interrupter. In order to closely examine the vacuum arc phenomena, it is necessary to predict the magnetohydrodynamic (MHD) characteristics by the multidisciplinary numerical modeling, which is coupled with the electromagnetic and hydrodynamic fields, simultaneously. In this study, we have investigated the electromagnetic behaviors of high-current vacuum arcs for two different types of AMF contacts, which are coil-type and cup-type, using a commercial finite element analysis (FEA) package, ANSYS. The present results are compared with those of MAXWELL 3D, a reliable electromagnetic analysis software, for verification.

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