• Title/Summary/Keyword: Penetration efficiency

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Design and Characterization of Ascorbyl Glucoside loaded Solid Lipid Nanoparticles to improve skin penetration (피부 투과 개선을 위한 고형지질나노입자내 Ascorbyl glucoside 봉입 설계 및 특성화)

  • Yeo, Sooho
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.3
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    • pp.662-668
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    • 2021
  • The aim of the present study was to design ascorbyl glucoside (AG) loaded solid lipid nanoparticles (SLNs) to improve skin penetration of AG. AG loaded SLNs were prepared using double emulsion method. The prepared AG loaded SLNs investigated particle characteristics (particle size, polydispersity index, zeta potential, loading capacity). Skin penetration study was carried out using SkinEthic RHE as one of the reconstructed human epidermis models. The mean particle size and zeta potential of SLNs were 172.65 - 347.19 nm and -22.90 - -41.20 mV, respectively. The loading capacity of AG loaded SLNs demonstrated that loading efficiency and loading amount were ranged from 44.18% to 57.77% and 12.83% to 16.15%, respectively. The results of penetration showed that all SLNs enhanced the skin penetration of AG and the amount of AG from SLNs were approximately 3.7 - 7.4 times higher than that from AG solution. Therefore, AG loaded SLN might be a promising topical drug delivery system.

Performance of Respirator Filters Using Quality Factor (qF) (양질계수(Quality Factor)를 이용한 방진마스크 필터의 성능평가)

  • Han, Don-Hee;Jeong, Yoon-Sok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.10 no.1
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    • pp.170-178
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    • 2000
  • Most of manufacturers try to produce the most efficient filter for respirators with the lowest breathing resistance. Filter performance depends on low penetration, i.e., high efficiency (%), and low pressure drop ($mmH_2O$). This study was performed to evaluate performance of respirator filters by quality factor ($q_F$) and suggest the direction for improvement of respirator filters of good quality in Korea. Two mechanical filters, S and K made in Korea, three filtering facepieces, S made in China, C made in Korea and M made in USA, which were widely used in the workplace, were selected and tested efficiency and pressure drop in accordance with flow rate, using with Automated Filter Tester Model 8110 (TSI, USA). The best quality factor within the same respirator filter categories was $0.0672cm^{-1}\;H_2O$ for mechanical filter S, $0.0698cm^{-1}\;H_2O$ for filtering facepiece M at flow rate of 32Lpm. Mechanical filter S would be the best suitable during heavy work since qulity factors decrease less sharply than any others as increased flow rates. It was necessary for mechanical filter S to lower pressure drop without increasing efficiency, but mechanical filter K should be increased efficiency and decreased pressure drop. While filtering facepiece M had the best quality performance of three ones, Sand C should get much higher efficiency and lower pressure for better performance.

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Mixing Performance of Unlike Doublet Impinging Liquid Jets (이중 충돌제트의 혼합 성능 연구)

  • Jo, Yong Ho;Lee, Seong Ung;Yun, Ung Seop
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.31 no.4
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    • pp.82-91
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    • 2003
  • Experiments to investigate the mixing performance of unlike doublet impinging jets are conducted. Reynolds number of simulants used in this study rages from 1.0 to 1.5 Cold flow test is performed to investigate the hydrodynamic effect and spray of the impinging jets are collected locally and calculated by using Rupe's mixing efficiency equation. Momentum exchanges and relative velocity ratio between two jets are taken as the main parameter to represent the effect of enlargement of the orifice diameter. As diameter ratio increases, the corresponding momentum ratio where maximum mixing efficiency occurs and relative velocity at the maximum mixing efficiency ranges 0.6 to 0.7, respectively. Penetration depth can be taken as a prominent parameter to estimate the mixing efficiency.

Ratio of Hammer Energy and Dynamic Efficiency of Standard Penetration Test (표준관입 시험 해머의 에너지비와 동적효율)

  • Lee, Chang-Ho;Lee, Woo-Jin
    • Journal of the Korean Geotechnical Society
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    • v.21 no.9
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    • pp.5-12
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    • 2005
  • SPT hammer energy and its delivery are hon to influence the N value. The SPT hammer energy is classified into theoretical energy, velocity energy, rod energy and dynamic efficiency. In this study, the rod energy and the velocity energy are measured directly by PDA and Digital Line-Scan Camera which are most widely used type of SPT apparatus in Korea. The Dynamic efficiency is calculated through measured data. As the results of this study, the averages of rod energy ratio of donut, safety and automatic hammer are measured at 49.57, 61.60, and at $87.04\%$ by FV method. The averages of hammer velocity of donut, safety and automatic hammer are measured at $3.177{\pm}0.872$, $3.385{\pm}0.681$, and at $3.651{\pm}0.550$ m/s by Digital Line-Scan Camera, with the dynamic efficiencies at 0.732, 0.801, and 0.973 respectively.

Filtration Efficiency of Granular Activated Carbons to Polydisperse Ultrafine Particles through the Surface Adsoprtion (그래뉼 타입 활성탄 필터의 100 나노 미만 다분산 초미세먼지 표면흡착 제거 효율 연구)

  • Cho, Kyungil;Kang, Giwon;Shin, Jiyoon;Kim, Changhyuk
    • Particle and aerosol research
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    • v.18 no.3
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    • pp.79-86
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    • 2022
  • Many commercial air purifiers currently have deployed granular activated carbon (GAC) filters for removing volatile organic compounds in the indoor air. GACs are generally used to remove gaseous contaminants in the air through adsorption by the inner surfaces of pores. In addition, airborne particles can be also filtered by the surface adsorption of the GACs, which can improve the life-time of the particulate filters. In this study, the filtration efficiency of GACs to ultrafine particles through surface adsorption was investigated at different volume flow rates by deploying a continuous particle filtration system. The polydisperse sodium chloride (NaCl) particles were generated by a set of an atomizer and a diffusion dryer, and then mixed with particle-free air at different volume flow rates. The penetration of ultrafine particles and pressure drop for each experimental condition were measured to figure out the effect of the volume flow rate on the surface adsoprtion of the GACs to particles, ~ 2 mm. The particle filtration efficiency of the GACs decreased as the volume flow rate increased from 4 to 14 lpm. However, the 5 times thicker GAC filter layer decreased the penetration of ultraparticles than a preious study. The filtration efficiency of the single granule was also higher than the previous result in the literature with smaller granule filter materials.

Microwave Treatment on Cold Pad Batch Process

  • Kim, Ji-Yeon;Park, Sung-Min;Han, Song-Jeong;Kim, Sam-Soo;Lee, Jae-Hong;Yeum, Jeong-Hyun
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2009.03a
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    • pp.213-214
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    • 2009
  • In order to promote an efficiency CPB process, we developed microwave system in CPB process. The whiteness and penetration ability of microwave-CPB pre-treated fabrics were superior to CPB only. This results indicates that microwave-CPB pre-treatment promotes CPB efficiency in agent usages and batching time.

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Study on the Addition and the Transfer of Alloying Elements in FCAW (FCAW에 의한 합금 성분의 첨가와 이행에 관한 연구)

  • 김경중;박관호
    • Journal of Welding and Joining
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    • v.1 no.2
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    • pp.76-82
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    • 1983
  • The chemical composition of deposit metal by flux cored arc welding can be easily regulated though addition of deoxidizers and alloying elements in cored flux and fluxes of flux coored wire arc analogous to those of coated electrode. It is necessary to investigate the transfer and yield efficiency due to addition of necessary alloy elements in deposit metal. This report is made to intorduce an experimental equation from the relation between welding condition and extent of penetration, deposit metal and weld melt slag and to estimate transfer and yield efficiency of alloy components in fluxes through chemical analysis of deposit metal.

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Mixing and Penetration Studies of Transverse Jet into a Supersonic Crossflow (초음속 유동 내 공동을 이용한 수직 분사 혼합 및 연료 침투거리에 관한 연구)

  • Kim, Chae-Hyoung;Jeong, Eun-Ju;Jeung, In-Seuck;Kang, Sang-Hun;Yang, Soo-Seok
    • Journal of the Korean Society of Propulsion Engineers
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    • v.12 no.2
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    • pp.24-32
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    • 2008
  • A non-reacting experimental study on a normal injection into a Mach 1.92 crossflow which flows over various geometries(flat plate, small cavity, large cavity) was carried out to investigate the effect of the momentum flux ratio(J). The aft ramp of the cavity advances the increase of the penetration height and the strong two-dimensional shock from recompression region mainly affects the shock structure and mixing layer at the downstream flow. As flow runs downward, the transverse penetration height increases with increasing J(J = 0.9, 1.7, 3.4). However, above some critical ratio, jet penetration height growth with increasing J is not appeared in flow-field. Large scale cavity has a good mixing efficiency but it increases the drag loss in the combustor.

Tile Size Dependency of Ballistic Performance in Alumina (알루미나의 시편크기가 방탄거동에 미치는 영향)

  • ;S.J. Bless
    • Journal of the Korean Ceramic Society
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    • v.32 no.3
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    • pp.366-370
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    • 1995
  • The ballistic efficiency of alumina tiles with various sizes, shapes, and target configurations was measured by the thick backing plate technique. The ballistic efficiency of square tiles roughly 8 mm thick struck by 12.7mm diameter bullets rapidly increased with tile size up to about 100mm, then tended to saturate. Circular shape tiles had lower ballistic efficiencies than those of square shape tiles for the same width and thickness. Small tiles (50mm) that were recessed in aluminum wells had a significantly higher ballistic efficiency than tiles placed on a flat surface. However, the difference in the ballistic efficiency between the two target configurtions became small at larger tile sizes. All the results could be explained by the effect of reflected waves at edges and the propagation of resulting cracks on the penetration process.

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A Study on Mixing Characterization of Unlike-doublet Injector for Liquid Rocket Engine (액체로켓용 Unlike-doublet 인젝터의 혼합특성 연구)

  • Lee, In-Su;Jung, Ki-Hoon;Lim, Byoung-Gjik;Yoon, Young-Bin
    • Journal of ILASS-Korea
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    • v.7 no.1
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    • pp.21-28
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    • 2002
  • The mixing of propellant and its mass distribution of unlike-doublet impinging injector, which is known to affect the combustion efficiency significantly, have been studied using PLIF(Planar Laser Induced Fluorescence). The results show that fuel jet penetrates considerably into the oxidizer jet at impinging point as variation of momentum ratio. and then stream flows inclined because of variation of momentum ratio. Consequently, the mixing efficiency shows that maximum efficiency is at MR=3. after MR=3, mining efficiency decreases slightly.

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