• Title/Summary/Keyword: Peak Age

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Seroprevalence of Toxoplasma gondii Infection and Characteristics of Seropositive Patients in General Hospitals in Daejeon, Korea

  • Shin, Dae-Whan;Cha, Dong-Yeub;Hua, Quan Juan;Cha, Guang-Ho;Lee, Young-Ha
    • Parasites, Hosts and Diseases
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    • v.47 no.2
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    • pp.125-130
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    • 2009
  • To figure out the epidemiological status and relevance with other diseases in toxoplasmosis, we checked serum IgG antibody titers of 1,265 patients and medical records of seropositive patients. Seropositive rates were 6.6% by latex agglutination test (LAT) and 6.7% by ELISA. No significant differences were detected between sexes and age groups. The peak seroprevalence was detected in the 40-49-year-old age group. According to clinical department, Toxoplasma-positive rates were high in patients in psychiatry, ophthalmology, health management, emergency medicine, and thoracic surgery. Major coincidental diseases in seropositive cases were malignant neoplasms, diabetes mellitus, arthritis, chronic hepatitis B, chronic renal diseases, schizophrenia, and acute lymphadenitis, in the order of frequency. In particular, some patients with chronic hepatitis B and malignant neoplasms had high antibody titers. These results revealed that the seroprevalence of toxoplasmosis in a general hospital-based study was similar to that in a community-based study, and T. gondii seropositivity may be associated with neoplasms, diabetes, and other chronic infections.

Clinical Study of Pulmonary Resection for Tuberculosis[IV] (폐결핵에대한 외과적 치험[제 4보])

  • Lee, S.;Ahn, W.S.;Hur, Y.;Kim, B.Y.;Lee, J.H.;Yu, H.S.
    • Journal of Chest Surgery
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    • v.25 no.1
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    • pp.79-85
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    • 1992
  • We have analyzed 1559 operated cases during the 32 year period, from October, 1958 to December, 1990. Annual incidence of the surgical treatment decreased from 101[1960] to 25[1990]. The ratio between male and female was 2.1: 1 and the age of peak incidence was in the 3rd and 4th decades. Recently, patients below the age of 20 years were decreased, but above 50 years were much increased. The patients were consisted of far-advanced case in 71.8% and moderately-advanced case in 22.0% in 1990, as compared with 44% and 54% correspondingly in 1960. Preoperative sputum positivity decreased from 91%[1958~1963] to 38%[1982~1990]. Preoperative antituberculous chemotherapy for more than 3 years increased from 16% [1958~1963] to 56.5% [1982~1990]. From the view of surgical indication, totally destroyed lung and destroyed lobe or segment has been main indication. Recently empyema with parenchymal lesion was increased, and so more extensive surgical resection such as pleuropneumonectomy was performed more frequently. The trends in the mode of surgical treatment revealed that thoracoplasty has virtually disappeared and operations required for residuals of pleural disease have increased. Postoperative mortality increased from 1.6-2.0% to 3.6% recently as well as morbidity. On the basis of our study, far-advanced and drug-resistant patients increased in number recently, whose pulmonary function was poor. So postoperative mortality and morbidity was increased despite improved anesthetic and surgical techniques. Proper surgical intervention should be considered before the appearance of resistance for all chemotherapeutic drugs.

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Follow up study of pulmonary function after pneumonectomy (일측 폐절제술후 폐기능의 추적관)

  • Park, Jae-Gil;Kim, Se-Hwa;Lee, Hong-Gyun
    • Journal of Chest Surgery
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    • v.16 no.4
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    • pp.539-546
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    • 1983
  • Maximal expiratory flow-volume [MEFV] curves were studied in 22 patients who underwent pneumonectomy with various pulmonary lesions, such as lung cancer, bronchiectasis and tuberculosis etc, at the preoperative stage and 3 week, 4 month and 12 month after pneumonectomy for the analysis of the reduction and progressive improvement of postoperative ventilatory function. And the factors affecting them like as age difference and the site of pneumonectomy were also analyzed. From these curves peak flow rate [PF R], maximal expiratory flows at 25% and 50% of expired forced vital capacity [V25, V50] and forced vital capacity [FVC] were obtained. In addition, partial pressure of oxygen and carbon dioxide in arterial blood were measured. The results were as follows; 1. The mixed type, especially obstructive type of ventilatory impairment was observed at 3 week after operation. For 1 year of postpneumonectomy FVC was increased by 12.3% of predicted compared to 2.6% of predicted V50. 2. The improvement of FVC during 1 year of postpneumonectomy showed decreasing tendency with the increase of age but the changes of V25 and V50 were unremarkable. 3. The differences of immediate postoperative reduction and progressive improvement of ventilatory capacity after right and left pneumonectomy were analyzed. The reduction of V50, V25 and FVC at 3 week of postoperation were greater in patients with right pneumonectomy [20.9%, 18.2% and 26.2% of predicted] than in patients with left pneumonectomy 16.5%, 18.2% and 18.1%]. But there was no significant difference of these values at 12 month after pneumonectomy. 4. The partial pressure of oxygen in arterial blood [$PaO_2$] was decreased by 13.6 mmHg at 3 week after pneumonectomy compared to the preoperative stage but returned to the normal range within 4 month after pneumonectomy. However, TEX>$PaCO_2$ was within the normal range during 1 year of postoperation.

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Effects of In on the Precipitation Phenomena of Al-2.1Li-2.9Cu Alloy by Differential Scanning Calorimetry (열분석법에 의한 Al-2.1Li-2.9Cu합금이 석출현상에 미치는 In 첨가의 영향)

  • Park, Tae-Won;Song, Young-Beum;Lee, Yong-Yun
    • Journal of the Korean Society for Heat Treatment
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    • v.10 no.4
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    • pp.237-245
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    • 1997
  • A study was conducted to examine the effects of In addition on the precipitation behaviors of Al-2.1Li-2.9Cu alloy by differential scanning calorimetry, transmission electron microscopy and micro-hardness tester. DSC analysis was measured over the temperature range of $25{\sim}550^{\circ}C$ at a heating rate of $2{\sim}20^{\circ}C$/min. The heat evolution peaks due to the formation of GP zone and ${\delta}$'phase shift to higher temperature and the peaks to $T_1$ and ${\theta}$'phases shift to lower temperature by In addition. From this result, it was proved that the formation of GP zone and ${\delta}$'phase is suppresed whereas that of $T_1$ and ${\theta}$'phases are accelerated by the In addition of 0.15wt%. The age hardening curve aged at $190^{\circ}C$ showed that the In bearing alloy(alloy B) has more faster age hardening response and a higher peak hardness than In-free alloy(alloy A), attributed to the fine and homogeneous distribution of $T_1$ and ${\theta}$'phases. The activation energies for the formation of ${\delta}$'phase in In-free and In-bearing alloys are 22.3kcal/mol and 18.6kcal/mol, respectively. Those for $T_1(+{\theta}^{\prime})$ phase of In-free and In-bearing alloys are 24.3 and 37.5kcal/mol, respectively. Quenched-in excess vacancies play an important role to the formation of precipitates.

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Experimental Study on the Early Strength Development Mechanism of Cement Paste Using Hardening Accelerator and High-Early-Strength Cement (경화촉진제와 조강시멘트를 사용한 시멘트 페이스트의 조기강도 발현 메커니즘에 관한 실험적 연구)

  • Min, Tae-Beom;Cho, In-Sung;Lee, Han-Seung
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.1
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    • pp.84-92
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    • 2014
  • The purpose of study is to analyze mechanism with early high portland cement and hardening accelerator. As the result, it was concluded that hardening accelerator makes accelerates appearance of $Ca(OH)_2$ through experiment using TG-DTA when it hydrates with cement. On the result of compressive strength, as increasing the amount of hardening accelerator used, early compressive strength was improved. Also, as a result of hydration heat, hardening accelerator accelerates hydration of $C_3S$ that is cement's component. On the result of XRD's analyzation, hydration product for each age could be check and it was shown that as increasing the amount of hardening accelerator used, peak point of hydration product was recorded high. As the result of SEM, appearance of C-S-H was shown as the amount of $Ca(OH)_2$'s appearance and each age according to additive contents of hardening accelerator. Therefore hardening accelerator used on this study is effective on getting early compressive strength.

Fundamental characteristics of high early strength low heat concrete according to mineral binder and high early strength material combination (광물질 결합재 및 조강형 재료 조합에 따른 조강형 저발열 콘크리트의 기초적 특성)

  • Kim, Kyoungmin;Son, Hojung
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.24 no.1
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    • pp.27-32
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    • 2014
  • This study analyzed the fundamental characteristics of concrete according to a ternary system mixing in order to reduce hydration heat of mass concrete and to improve early age strength. The results are as follows. The fluidity of unconsolidated concrete satisfied the target scope regardless of the binder conditions. When the replacement ratio between FA and BS increased, the slump of low heat-A mix and low heat-B mix increased, and air content was not affected by the change of binders. As for setting time, low heat cement mix had the fastest regardless of W/B, and high early strength low heat mix achieved 6 hours' reduction compared with low heat-B mix at initial set, and 12 hours' reduction at the final set respectively. As for the simple hydration heat, the low mix peak temperature was the highest and low heat-B mix had the lowest temperature. And high early strength low heat mix was similar with that of low heat-B. The compressive strength of hardened concrete had similar strength scope in all mixes except for low heat-B mix at early ages, and had unexceptionally similar one without huge differences at long-term ages.

Prognostic Factors of Soft Tissue Sarcomas - analysis of 205 cases - (연부 육종의 예후 인자 - 205례 분석 -)

  • Lee, Jong-Seok;Jeon, Dae-Geun;Lee, Soo-Yong;Kim, Sug-Jun;Jung, Dong-Whan;Park, Hyun-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.3 no.2
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    • pp.89-97
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    • 1997
  • Twenty hundred and five out of 266 patients who were registered in Korea Cancer Center Hospital from Mar. 1985 to Jan. 1994, were analyzed in the aspect of survival and local recurrence. Fifty one patients were excluded due to inadequate data and follow up. Prognostic factors for survival were evaluated statistically. One hundred and four cases were male, 101 female. Average age was 39.7(range 1 to 77) year with a peak incidence around 4th decade. The most frequent diagnosis was malignant fibrous histiocytoma(MFH)(24.1%). Liposarcoma, synovial sarcoma, rhabdomyosarcoma, malignant peripheral nerve sheath tumor and fibrosarcoma were relatively common diagnostic entities, in decreasing order. In location, extremity was 179(87.3%) and trunk 26(12.7%). Average follow up period was 7.5 years(6 months to 10 years). Actuarial 5 years and 10 years survival rate were 64.0% and 40.8% respectively. In univariate analysis with log-lank test, significant differences in survival rate were noted in histopathological diagnosis, size(10 cm), stage and metastasis. Age, sex, tumor location, tumor depth and local recurrence didn't affect the survival rate. Adjuvant chemotherapy and/or radiotherapy did not affect overall survival rate, but lowered the local recurrence rate when compared with surgery only. Surgical margin did not affect the survival rate, but local recurrence rate was different according to each margin; 5.7% in more than wide; 39.5% in marginal; and 60.0% in intralesional excision. In multivariate analysis for results of univariate analysis with Cox's propotional model, metastasis was a meaningful factor for survival of soft tissue sarcoma.

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Blunt Abdominal Trauma in Children (소아 복부 외상에 관한 임상적 고찰)

  • Kim, Dong-Hyun;Seo, Sang-Hyuk;Lee, Nan-Joo;Chun, Yong-Soon
    • Advances in pediatric surgery
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    • v.13 no.2
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    • pp.119-126
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    • 2007
  • Trauma is one of the leading causes of death in children. Abdominal trauma is about 10 % of all pediatric trauma. This study describes the sex and age distribution, injury mechanism, site of intraabdominal injury, management and mortality of children aged 16 years or less who suffered abdominal trauma. The hospital records of 63 patients treated for abdominal injury between March 1997 and February 2007 at the department of surgery, Inje University Pusan Paik Hospital, were analyzed retrospectively. The peak age of incidence was between 2 and 10 years (78%) and this report showed male predominance(2.7:1). The most common mechanism of blunt abdominal trauma was pedestrian traffic accident (49%). The most common injured organ was liver. More than Grade IV injury of liver and spleen comprised of 4(12%) and 5(24%), respectively. Fourteen cases (22%) had multiple organ injuries. Forty nine cases (78%) were managed nonoperatively. Three patients (4.8%) died, who had Grade IV liver injury, Grade IV spleen injury, and liver and spleen injury with combined inferior vena cava injury, respectively. All of the three mortality cases had operative management. In conclusion, the liver or spleen injury which was more than Grade 4 might lead to mortality in spite of operation, although many cases could be improved by nonoperative management.

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Analysis of Angular Velocity during Toe Tapping for the Quantification of the Lower Limb Bradykinesia in Patients with Idiopathic Parkinson's Disease (특발성 파킨슨병 환자의 하지 완서증 정량화를 위한 발 두드리기 동작의 각속도 분석)

  • Kim, Ji-Won;Kwon, Yu-Ri;Eom, Gwang-Moon;Kim, Hyung-Sik;Yi, Jeong-Han;Kwon, Do-Young;Koh, Seong-Beom;Park, Byung Kyu;Kwon, Tae-Kyu
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.11
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    • pp.2114-2118
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    • 2010
  • The purpose of this study was to analyze bradykinesia of toe tapping movement in patients with Parkinson's disease (PD) as compared to those of normal subjects. 39 PD patients (age: $65.5{\pm}11.2$ yrs, H&Y stage:$2.3{\pm}0.5$), 14 eldelry subjects with comparable mean age ($65.0{\pm}3.9$ yrs) and 17 healthy young subjects ($24.1{\pm}2.1$ yrs) participated in this study. Angular velocity during repetitive toe tapping movement was measured in both feet using a gyro sensor system. Suggested quantitative measures of bradykinesia were root-mean-squared (RMS) angular velocity, RMS angle, peak power and total power which were derived from the angular velocity signal. ANOVA showed that all measures were significantly different among three groups (p<0.001). Subsequent post-hoc test revealed that all measures in PD patients were significantly smaller than in healthy elderly and healthy young subjects (p<0.02). All measures were significantly correlated with UPDRS scores(r=-0.689~-0.825). These results suggest that the developed system can be used as quantitative measures of the lower limb bradykinesia in PD patients.

Effects of Cu and Ag Addition on Nanocluster Formation Behavior in Al-Mg-Si Alloys

  • Kim, Jae-Hwang;Tezuka, Hiroyasu;Kobayashi, Equo;Sato, Tatsuo
    • Korean Journal of Materials Research
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    • v.22 no.7
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    • pp.329-334
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    • 2012
  • Two types of nanoclusters, termed Cluster (1) and Cluster (2) here, both play an important role in the age-hardening behavior in Al-Mg-Si alloys. Small amounts of additions of Cu and Ag affect the formation of nanoclusters. Two exothermic peaks were clearly detected in differential scanning calorimetry(DSC) curves by means of peak separation by the Gaussian method in the base, Cu-added, Ag-added and Cu-Ag-added Al-Mg-Si alloys. The formation of nanoclusters in the initial stage of natural aging was suppressed in the Ag-added and Cu-Ag-added alloys, while the formation of nanoclusters was enhanced at an aging time longer than 259.2 ks(3 days) of natural aging with the addition Cu and Ag. The formation of nanoclusters while aging at $100^{\circ}C$ was accelerated in the Cu-added, Ag-added and Cu-Ag-added alloys due to the attractive interaction between the Cu and Ag atoms and the Mg atoms. The influence of additions of Cu and Ag on the clustering behavior during low-temperature aging was well characterized based on the interaction energies among solute atoms and on vacancies derived from the first-principle calculation of the full-potential Korrinaga-Kohn-Rostoker(FPKKR)-Green function method. The effects of low Cu and Ag additions on the formation of nanoclusters were also discussed based on the age-hardening phenomena.