• 마이크로전자및패키징학회지
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• 제30권2호
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• pp.65-70
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• 2023

나노임프린트 리소그래피(Nanoimprint lithography, NIL) 공정은 패턴 형성을 위한 공정 단순성, 우수한 패턴 형성, 공정의 확장성, 높은 생산성 및 저렴한 공정 비용이라는 이유들로 인해 많은 관심을 받고 있다. 그러나, 기존의 NIL 기술들을 통해 금속 소재 상 구현할 수 있는 패턴의 크기는 일반적으로 마이크로 수준으로 제한적이다. 본 연구에서는, 다양한 두께의 금속 기판 표면에 마이크로/나노 스케일 패턴을 직접적으로 형성하기 위한 극압 임프린트 리소그래피(extremepressure imprint lithography, EPIL) 방법을 소개하고자 한다. EPIL 공정은 자외선, 레이저, 임프린트 레지스트 또는 전기적 펄스 등의 외부 요인을 사용하지 않고 고분자, 금속, 세라믹과 같은 다양한 재료의 표면에 신뢰성 있는 나노 수준의 패터닝을 가능하게 한다. 레이저 미세가공 및 포토리소그래피로 제작된 마이크로/나노 몰드는 상온에서 높은 하중 혹은 압력을 가해 정밀한 소성변형 기반 Al 기판의 나노 패터닝에 활용된다. 20 ㎛ 부터 100 ㎛까지 다양한 두께를 갖는 Al 기판 상 마이크로/나노 스케일의 패턴 형성을 보여주고자 한다. 또한, 다목적 EPIL 기술을 통해 금속 재료 표면에서 그 형상을 제어하는 방법 역시 실험적으로 증명된다. 임프린트 리소그래피 기반 본 접근법은 복잡한 형상이 포함된 금속 재료의 표면을 요구하는 다양한 소자 응용을 위한 나노 제조 방법에 적용될 수 있을 것으로 기대한다.

• Archives of Plastic Surgery
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• 제42권2호
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• pp.179-185
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• 2015

Background Capsular contracture is the most troublesome complication in breast implant surgery. Although capsule formation can be seen as a normal reaction to a foreign body, it can induce pain, hardness, deformity, and other pathologic problems. Surgical intervention is required in severe cases, but even surgery cannot guarantee a successful outcome without recurrence. This experimental study confirms that single topical administration of leukotriene antagonist zafirlukast (Accolate, Astrazeneca) reduces peri-implant capsule formation and prevents capsular contracture. Methods Twelve smooth-surfaced cohesive gel implants were implanted in New Zealand White rabbits. These miniature implants were designed to be identical to currently used products for breast augmentation. The rabbits were divided into 2 groups. In the experimental group (n=6), the implant and normal saline with zafirlukast were inserted in the submuscular pocket. In the control group (n=6), the implant and normal saline alone were used. Two months later, the implants with peri-implant capsule were excised. We evaluated capsule thickness and collagen pattern and performed immunohistochemical staining of myofibroblasts, transforming growth factor $(TGF)-{\beta}1$, 2. Results The thickness of the capsules in the experimental group was reduced in both dorsal and ventral directions. The collagen pattern showed parallel alignment with low density, and the number of myofibroblasts as well as the amounts of $TGF-{\beta}1$ and $TGF-{\beta}2$ were reduced in the experimental group. Conclusions We suggest that single topical administration of leukotriene antagonist zafirlukast can be helpful in reducing capsule formation and preventing capsular contracture via myofibroblast suppression, modulation of fibroblastic cytokines, and anti-inflammatory effect.

• 복식문화연구
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• 제16권5호
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• pp.863-877
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• 2008

The purpose of this study is to investigate the effect of dot pattern size(0.8, 1.8, 2.5, 5, 8), color combination (BG/R, Y/B), value tone(lt/dk, p/g), area-ratio on image information. Sets of stimulus and response scales(7 point semantic) were used as experimental materials. The stimuli were 20 color pictures manipulated with the combination of dot pattern size, color combination, value tone and area-ratio using computer simulation. The subjects were 240 female undergraduates living in Gyeongsangnam-do. Image factor of the stimulus was composed of 4 different components, visibility, chastity.feminity, cuteness and attractiveness. In the visibility, color combination, value tone, area-ratio, dot pattern size showed independent effect. In the chastity feminity, color combination, value tone, showed independent effect. In the cuteness, value tone, area-ratio, dot pattern size showed independent effect. Significant interaction effects of color and area-ratio combination on visibility and cuteness were found. Interaction efforts of color and value tone combination, value tone and area-ratio was significant on cuteness. For visibility image, BG/R combination of color and yellow background/blue dots were effective. For cuteness image, pale/grayish tone and background/dots area-ratio were effective.

• 한국의상디자인학회지
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• 제8권3호
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• pp.1-15
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• 2006

The purpose of this research is to find out the effect of clothing style and mixtures of stripe pattern direction, width, and coloration of an upper garment. The experimental materials made for this study are a set of stimuli and response scale(The 7-Point semantic). The subjects were 480 female undergraduate students in Seoul, Busan, Gyung-nam. The 80 stimuli which were variously incorporated with clothing styles and stipe patterns were assessed by the students. The following contents summarizes the results of the research. Impression factors of the stimuli consists of the 5 dimensions(Attractiveness, Show, Activity, Clearness, mildness). Amon these, the Attractiveness and Show dimensions proved to be more important. The clothing style and pattern direction indicated main effect in attractiveness and activity dimension. The pattern coloration showed a significant effect in dimensions except attractiveness and clearness. The pattern width had a significant effect only in the activity. Significant interaction effects of each clothing clause were found in the attractiveness, activity and clearness, but Show and mildness had no significant interaction effect. This research, as the 06 S/S, F/W trend, is a meaningful study in that it handled in the form of expression the stripe pattern used unrestrictedly in the casual wear or the formal wear by a fashion keyword.

• 한국기계가공학회지
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• 제17권3호
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• pp.1-6
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• 2018

Micro prism pattern is applying in order to get increase of luminance, control the light, and so forth especially in optics and display industry. Most patterns are fabricated by lithography, planning, and EDM, but they have limitations on the productivity or the unit cost of produce. However, ultra precision mold is one of the processes able to replace it, and assure high productivity required by industries. In this investigation, micro prismatic end-milling is suggested in order to fabricate the pattern effectively. Micro prism pattern having $100{\mu}m$ of pitch and height was machined on STD-11. After machining, the flank and boundary wear on micro end mill were measured and analyzed, as well as burr formation and dimensional accuracy of fabricated pattern were evaluated. Thus the optimal cutting conditions were derived.

• 한국과학교육학회지
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• 제24권3호
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• pp.638-645
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• 2004

본 연구에서는 학생들의 창의적 문제해결력과 비판적 사고력을 함양하기 위한 프로그램으로 온라인 물리탐구토론 학습체제를 개발하여, 온라인 물리탐구토론에 참여한 학생들의 상호작용 유형을 단위토론에서의 참여자 수, 다중토론장의 형성, 대화의 이동을 중심으로 구분하여 개인간 상호작용 유형, 일대일 참여의 상호작용 유형, 다중참여로 인한 일대다 상호작용 유형, 다대다 상호작용 유형등으로 분류하였다. 이는 사이버 상에서 벌어지는 학생들의 참여구조와 상호작용 양상을 파악할 수 있어 온라인을 통한 교육의 방향에 좋은 정보를 제공해 줄 수 있을 것으로 기대한다.

• 복식
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• 제58권6호
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• pp.54-68
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• 2008

The purpose of this study is to investigate the effect of dot pattern size(0.8, 1.8, 2.5, 5, 8), color combination(BG/R, Y/B), area-ratio on image formation. Sets of stimulus and response scales(7 point semantic) were used as experimental materials. The stimuli were 20 color pictures manipulated with the combination of dot pattern size, color combination, and area-ratio using computer simulation. The subjects were 240 female undergraduates living in Gyeongnam-do. Image factor of the stimulus was composed of 5 different components, visibility, attractiveness, cuteness, stability and high class image. In the cuteness, color combination, dot pattern size showed independent effect. In the stability, area-ratio, dot pattern size showed independent effect. Interaction effects of color and area-ratio combination was significant on cuteness. For visibility image 8cm yellow dot/blue background, for attractiveness image BG/R coloration, for cuteness image Y/B coloration and for stability image 0.8cm yellow dot/blue background were effective. According to the variation of dot pattern size, color combination and area-ratio, it was investigated that the images for a dress wearer were expressed diversely, were shown differently in image dimensions, and could be produced to different images.

• 한국자동차공학회논문집
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• 제14권2호
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• pp.76-83
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• 2006

Each tire has a critical speed at which a standing wave phenomenon occurs along the circumferential direction. If the standing waves are formed, the tire temperature is rapidly increased and it leads to tire failure eventually. As the formation of the standing waves is closely related to the tire stiffness, the effect of the tread pattern needs to be studied numerically. The standing wave phenomenon of a tire model with tread pattern is predicted by an explicit finite element method. The critical speed of the tire with tread pattern is in a good agreement with the experiment and is $15{\sim}20\;km/h$ lower than that of the tire without tread pattern. The effects of the inflation pressure and the vertical load on the critical speed are also investigated by using the tire model with tread pattern.

• 폴리머
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• 제29권4호
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• pp.331-337
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• 2005

일반적으로 꼬리부분에 카복실산을 갖는 알칸티올레이트는 바이오 물질의 고정화 활성물질로 사용되고 있다. 본 연구에서는 알칸티올레이트의 전기적 성질과 물리적 안정성을 향상시키기 위해 공액구조를 갖는 방향족계 티올레이트를 사용하여 cytochrome c와 같은 단백질을 고정화시켰다. 방향족계 자기조립 단분자막의 패턴 형성은 다음과 같은 공정으로 행하였다. 4'-Mercapto-biphenyl-4-carboxylic acid와 4-mercapto-[1,1';4',1']terphenyl-4'-carboxylic acid와 같은 방향족 티올레이트 분자를 금 기판에 흡착시킨 다음 네거티브 마스크를 가지고 원자외선 조사에 의해 산화반응을 시킨 후 deioniz water로 현상하였다. 공액계 자기조립 단분자막의 패턴형성과 전기적 성질은 STM과 AFM 측정을 통해 조사하였다. 또한 cytochrome c 또는 ferrocene amide를 패턴이 형성된 금 기판에 고정화시킨 다음 cyclic voltammeoy 측정을 통해 공액계 방향족 티올레이트의 전기적 활성을 검토하였다.

• 대한수의학회지
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• 제35권1호
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• pp.95-105
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• 1995

The human homolog of position specific element of mouse Hoxa-7 was studied using transgene. It contains a 1.1 kb human DNA (HCR)- a homolog to the intergenic region between Hoxa-7 and -9, which directs the position specific expression of Hoxa-7-, tk promoter, LacZ (${\beta}$-galactosidase) gene as a reporter, and polyadenylation signal of SV40 large T antigen. It was injected into the mice embryos, and the resulting transgenic embryos were analysed through PCR as well as genomic Southern blotting with placenta DNA. Out of 20 embryos analysed, two were transgenic. Among them, one transgenic embryo expressed transgene when stained with X-gal. The expression pattern was in analogy to that of the mouse Hoxa-7, showing spatially restricted expression pattern, Since the expression of ${\beta}$-galactosidase is regulated by the upstream human HCR sequence, it implies that the HCR is the plausible position specific regulatory element of human.