• Journal of the Microelectronics and Packaging Society
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• v.30 no.2
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• pp.65-70
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• 2023

Nanoimprint lithography (NIL) has attracted much attention due to its process simplicity, excellent patternability, process scalability, high productivity, and low processing cost for pattern formation. However, the pattern size that can be implemented on metal materials through conventional NIL technologies is generally limited to the micro level. Here, we introduce a novel hard imprint lithography method, extreme-pressure imprint lithography (EPIL), for the direct nano-to-microscale pattern formation on the surfaces of metal substrates with various thicknesses. The EPIL process allows reliable nanoscopic patterning on diverse surfaces, such as polymers, metals, and ceramics, without the use of ultraviolet (UV) light, laser, imprint resist, or electrical pulse. Micro/nano molds fabricated by laser micromachining and conventional photolithography are utilized for the nanopatterning of Al substrates through precise plastic deformation by applying high load or pressure at room temperature. We demonstrate micro/nanoscale pattern formation on the Al substrates with various thicknesses from 20 ㎛ to 100 mm. Moreover, we also show how to obtain controllable pattern structures on the surface of metallic materials via the versatile EPIL technique. We expect that this imprint lithography-based new approach will be applied to other emerging nanofabrication methods for various device applications with complex geometries on the surface of metallic materials.

• Archives of Plastic Surgery
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• v.42 no.2
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• pp.179-185
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• 2015

Background Capsular contracture is the most troublesome complication in breast implant surgery. Although capsule formation can be seen as a normal reaction to a foreign body, it can induce pain, hardness, deformity, and other pathologic problems. Surgical intervention is required in severe cases, but even surgery cannot guarantee a successful outcome without recurrence. This experimental study confirms that single topical administration of leukotriene antagonist zafirlukast (Accolate, Astrazeneca) reduces peri-implant capsule formation and prevents capsular contracture. Methods Twelve smooth-surfaced cohesive gel implants were implanted in New Zealand White rabbits. These miniature implants were designed to be identical to currently used products for breast augmentation. The rabbits were divided into 2 groups. In the experimental group (n=6), the implant and normal saline with zafirlukast were inserted in the submuscular pocket. In the control group (n=6), the implant and normal saline alone were used. Two months later, the implants with peri-implant capsule were excised. We evaluated capsule thickness and collagen pattern and performed immunohistochemical staining of myofibroblasts, transforming growth factor $(TGF)-{\beta}1$, 2. Results The thickness of the capsules in the experimental group was reduced in both dorsal and ventral directions. The collagen pattern showed parallel alignment with low density, and the number of myofibroblasts as well as the amounts of $TGF-{\beta}1$ and $TGF-{\beta}2$ were reduced in the experimental group. Conclusions We suggest that single topical administration of leukotriene antagonist zafirlukast can be helpful in reducing capsule formation and preventing capsular contracture via myofibroblast suppression, modulation of fibroblastic cytokines, and anti-inflammatory effect.

• The Research Journal of the Costume Culture
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• v.16 no.5
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• pp.863-877
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• 2008

The purpose of this study is to investigate the effect of dot pattern size(0.8, 1.8, 2.5, 5, 8), color combination (BG/R, Y/B), value tone(lt/dk, p/g), area-ratio on image information. Sets of stimulus and response scales(7 point semantic) were used as experimental materials. The stimuli were 20 color pictures manipulated with the combination of dot pattern size, color combination, value tone and area-ratio using computer simulation. The subjects were 240 female undergraduates living in Gyeongsangnam-do. Image factor of the stimulus was composed of 4 different components, visibility, chastity.feminity, cuteness and attractiveness. In the visibility, color combination, value tone, area-ratio, dot pattern size showed independent effect. In the chastity feminity, color combination, value tone, showed independent effect. In the cuteness, value tone, area-ratio, dot pattern size showed independent effect. Significant interaction effects of color and area-ratio combination on visibility and cuteness were found. Interaction efforts of color and value tone combination, value tone and area-ratio was significant on cuteness. For visibility image, BG/R combination of color and yellow background/blue dots were effective. For cuteness image, pale/grayish tone and background/dots area-ratio were effective.

• Journal of the Korea Fashion and Costume Design Association
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• v.8 no.3
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• pp.1-15
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• 2006

The purpose of this research is to find out the effect of clothing style and mixtures of stripe pattern direction, width, and coloration of an upper garment. The experimental materials made for this study are a set of stimuli and response scale(The 7-Point semantic). The subjects were 480 female undergraduate students in Seoul, Busan, Gyung-nam. The 80 stimuli which were variously incorporated with clothing styles and stipe patterns were assessed by the students. The following contents summarizes the results of the research. Impression factors of the stimuli consists of the 5 dimensions(Attractiveness, Show, Activity, Clearness, mildness). Amon these, the Attractiveness and Show dimensions proved to be more important. The clothing style and pattern direction indicated main effect in attractiveness and activity dimension. The pattern coloration showed a significant effect in dimensions except attractiveness and clearness. The pattern width had a significant effect only in the activity. Significant interaction effects of each clothing clause were found in the attractiveness, activity and clearness, but Show and mildness had no significant interaction effect. This research, as the 06 S/S, F/W trend, is a meaningful study in that it handled in the form of expression the stripe pattern used unrestrictedly in the casual wear or the formal wear by a fashion keyword.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.3
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• pp.1-6
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• 2018

Micro prism pattern is applying in order to get increase of luminance, control the light, and so forth especially in optics and display industry. Most patterns are fabricated by lithography, planning, and EDM, but they have limitations on the productivity or the unit cost of produce. However, ultra precision mold is one of the processes able to replace it, and assure high productivity required by industries. In this investigation, micro prismatic end-milling is suggested in order to fabricate the pattern effectively. Micro prism pattern having $100{\mu}m$ of pitch and height was machined on STD-11. After machining, the flank and boundary wear on micro end mill were measured and analyzed, as well as burr formation and dimensional accuracy of fabricated pattern were evaluated. Thus the optimal cutting conditions were derived.

• Journal of The Korean Association For Science Education
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• v.24 no.3
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• pp.638-645
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• 2004

In this study, the on-line discussion learning system of physics investigation was developed for developing the creativity in the problem solving and critical thinking. And with the number of participants of a topic unit, the formation of multiple discussion field and a turn-taking, we found that the interaction patterns of the students were composed of interpersonal interaction pattern, interaction pattern of one to one participation, interaction pattern of one to many participation and interaction pattern of many to many participation. These interaction patterns could make us understand the participation structure and the aspect of interaction of the students in the cyber space.

• Journal of the Korean Society of Costume
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• v.58 no.6
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• pp.54-68
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• 2008

The purpose of this study is to investigate the effect of dot pattern size(0.8, 1.8, 2.5, 5, 8), color combination(BG/R, Y/B), area-ratio on image formation. Sets of stimulus and response scales(7 point semantic) were used as experimental materials. The stimuli were 20 color pictures manipulated with the combination of dot pattern size, color combination, and area-ratio using computer simulation. The subjects were 240 female undergraduates living in Gyeongnam-do. Image factor of the stimulus was composed of 5 different components, visibility, attractiveness, cuteness, stability and high class image. In the cuteness, color combination, dot pattern size showed independent effect. In the stability, area-ratio, dot pattern size showed independent effect. Interaction effects of color and area-ratio combination was significant on cuteness. For visibility image 8cm yellow dot/blue background, for attractiveness image BG/R coloration, for cuteness image Y/B coloration and for stability image 0.8cm yellow dot/blue background were effective. According to the variation of dot pattern size, color combination and area-ratio, it was investigated that the images for a dress wearer were expressed diversely, were shown differently in image dimensions, and could be produced to different images.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.2
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• pp.76-83
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• 2006

Each tire has a critical speed at which a standing wave phenomenon occurs along the circumferential direction. If the standing waves are formed, the tire temperature is rapidly increased and it leads to tire failure eventually. As the formation of the standing waves is closely related to the tire stiffness, the effect of the tread pattern needs to be studied numerically. The standing wave phenomenon of a tire model with tread pattern is predicted by an explicit finite element method. The critical speed of the tire with tread pattern is in a good agreement with the experiment and is $15{\sim}20\;km/h$ lower than that of the tire without tread pattern. The effects of the inflation pressure and the vertical load on the critical speed are also investigated by using the tire model with tread pattern.

• Polymer(Korea)
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• v.29 no.4
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• pp.331-337
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• 2005

In general, alkanethiolates having carboxylic acid in the tail group have been used as biorecepton. In this study, we have immobilized a cytochrome c protein using conjugated aromaticthiolates in order to improve the electrical property and physical stability of alkanethilolates. The pattern formation of self-assembled aromaticthiolate monolayers was as follow. Aromatic thiolates bound on the gold surface by the adsorption of 4'-mercapto-biphenyl-4-carboxylic acid and 4-mercapto-[1,1';4',1']terphenyl-4'-carboxylic acid were oxidized by the irradiation of deep UV light through a negative mask. The negative type pattern of the self-assembled monolayer (SAM) was obtained by developing with a deionized water. The pattern formation and electrical conductivity of aromaticthiolate SAMs was investigated by the measurements of STM and AFM. In addition, cytochrome c or ferrocene amide was immobilized onto the patterned substrate. We also studied on the effect of conjugated aromatic thiolates on the electrical activity of cytochrome c or ferrocene amide by cyclic voltammetry.

• Korean Journal of Veterinary Research
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• v.35 no.1
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• pp.95-105
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• 1995

The human homolog of position specific element of mouse Hoxa-7 was studied using transgene. It contains a 1.1 kb human DNA (HCR)- a homolog to the intergenic region between Hoxa-7 and -9, which directs the position specific expression of Hoxa-7-, tk promoter, LacZ (${\beta}$-galactosidase) gene as a reporter, and polyadenylation signal of SV40 large T antigen. It was injected into the mice embryos, and the resulting transgenic embryos were analysed through PCR as well as genomic Southern blotting with placenta DNA. Out of 20 embryos analysed, two were transgenic. Among them, one transgenic embryo expressed transgene when stained with X-gal. The expression pattern was in analogy to that of the mouse Hoxa-7, showing spatially restricted expression pattern, Since the expression of ${\beta}$-galactosidase is regulated by the upstream human HCR sequence, it implies that the HCR is the plausible position specific regulatory element of human.