• Korean Chemical Engineering Research
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• v.47 no.4
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• pp.488-494
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• 2009

Zeolite 4A was prepared by new synthesis method, 2-step crystallization, for enhancement of oil absorption capacity. Vietnamese sand and $NaAlO_2$ solution from natural bauxite were used as raw materials in stead of conventional cullet and $Al(OH)_3$ to reduced the processing cost. Some dissolved organics in $NaAlO_2$ solution were removed by activated carbon. Synthetic method was progressed by 1) reacting the raw materials at $55^{\circ}C$, 4 hr with the ratio of Si/Al to 1.15, and 2) reacting at $65^{\circ}C$, 5 hr with reducing the ratio of Si/Al to 0.98. New method can easily control the particle size, aggregation, surface polarity, and enhanced the whiteness of the products. The prepared zeolite 4A shows excellent oil absorption capacity(O.A.C>50 ml/100 g) as well as equal value with calcium ion exchange capacity, and proves the 2-step crystallization is the economic and effective process for the preparation of zeolite 4A.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.16 no.3
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• pp.233-244
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• 2006

Of many volatile organic detergents for metals, benzine(CAS No. 8030-30-6), of which the toxicity has not yet been proven, has been used as an alternative of the halide compounds in the consideration of toxic effects, global warming and the destruction of ozone layer. In order to evaluate the effects of the benzine on human body by investigating the subchronic inhalation toxicity, to obtain the basic data for establishing the criteria of exposure in working environments and to classify the hazardousness in compliance with the Industrial Safety and Health Act by evaluating the hazardousness, repeated inhalation exposure test was carried with SD rats. The rats were grouped by 10 females and males each. The repetitive inhalation exposures were carried out at 4 levels of concentration of 0 ppm, 60 ppm, 300 ppm, and 1,500 ppm, for 6 hours a day, 5 days a week, for 13 weeks. The results are described hereunder. 1. No death of the animals of the exposed and controlled groups in the test period. Not any specific clinical symptoms, change in feed intake quantity, abnormality in eye test, or change in activity were observed. 2. In the 300 ppm and 1,500 ppm groups, weight reduction in the female groups and weight increase of liver and kidney in the male groups compared with control group were observed with statistical significance(p<0.05). 3. In the blood test, the HCT increased in the male 300 ppm group and the number of hematocyte increased, MCV and MCH decreased in the male 1,500 ppm group. In the female 1,500 ppm group, the HB decreased and the distribution width of the hematocyte particle size increased. In the blood biochemistry test, the TP in the male 1,500 ppm group and the LDH in the female 1,500 ppm group were increased with statistical significance(p<0.05). 4. Under the test conditions of the present study with SD rats, the NOEL was evaluated to be from 60 ppm to 300 ppm for both male and female groups. By extrapolation, the NOEL for human who work 8 hours a day was evaluated to be from 128 ppm to 640 ppm 5. Since the NOEL evaluated in this study do not exceed 60ppm(0.184 mg/L) the test material does not belong to the classification of the hazardous substance "NOEL${\leq}$0.5mg/L/6hr/90day(rat), for continuous inhalation of 6hours a day for 90 days" nor to the basic hazardous chemical substance class 1(0.2 mg/L/6hr/90day(rat) defined by the GHS which is a criteria of classification and identification of chemical compounds. However, considering the boiling point($30-204^{\circ}C$), flashing point($-40^{\circ}C$), vapor pressure(40 mmHg), and the inflammable range(1.0 - 6.0 %), sufficient care should be taken for handling in the safety aspects including fire or explosion.

• Journal of the Korean Geographical Society
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• v.42 no.4
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• pp.506-525
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• 2007

Incision into bedrock channel is the primary control of landform evolution, but research into bedrock incision process stagnated for long time. Due to the scaling problem of the application of results from flume studies to bedrock channel, there is a strong need to simulate the bedrock incision process with more realistic models. As a part of investigation into controls of bedrock channel incision, three-dimensional changes of rock surface with abrasion was investigated with physical modelling. 18 rock plates were abraded with various sediment particle size and sediment load and abraded surfaces of the plates were scanned with high resolution 3-D scanner. To identify the spatial pattern of erosion of the rock plates, various methods were used. There was no synthetic or holistic method that showed all features of bedrock plate produced by abrasion, so each plate was analyzed using some available methods. Contour maps, shaded relief maps and profiles show that abrasion concentrated on the centre of plate (cross profile) and upstream and downstream edges (longitudinal profile) and eroded area extended inwards. It also found that the cracks and boundaries of forming materials easily eroded than other parts. Changing patterns of surface roughness were investigated with profiles, regression analysis and spectral analysis. Majority of plates showed decrease in small-scale roughness, but it depends on microstructures of the plates rather than general hardness or other factors. SEM inspection results supported this idea.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.10 no.1
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• pp.56-68
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• 2005

We measured nitrate and other nutrients in sediment pore waters retrieved from three sites at the southern upper-tidal flats of the Ganghwa Island. Denitrification rate is estimated by applying a simple 1-D model to the nitrate profiles. Results from Jangwha and Dongmak sites are $7.8{\sim}9.4{\times}10^{-7}{\mu}mol{\cdot}cm^{-2}{\cdot}sec^{-1}$, and $1.4{\sim}3.6{\times}10^{-7}{\mu}mol{\cdot}cm^{-2}{\cdot}sec^{-1}$, respectively. Rates are comparable to those reported around the world in an order of magnitude. Denitrification was lower in summer. The rates were about 1.5 times higher at site where the surface sediments consist of relatively coarser particles. This implies that particle size would control the reactant supply to the subsurface sediment. One may claim the denitrification as an evidence of the biogeochemical purification function of tidal flat. However, the purification seems not a general attribute of a tidal flat when whole system is scrutinized by a thermodynamic criterion. Currently the term 'tidal flat' is used when describing the diverse coastal wetlands such as salt marshes, sandy tidal flats and muddy tidal flats, which exhibit quite different ecological functions. Thus it is worthy of mentioning that the classification of coastal wetlands on the basis of sedimentological characteristics and biogeochemical functions should facilitate our understanding.

• Journal of Veterinary Clinics
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• v.32 no.3
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• pp.224-230
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• 2015

This study was designed in the fabricated poly (L-Lactic-co-${\varepsilon}$-Caprolactone) (PLCL) scaffold using chitosan-alginate hydrogel, which would be more suitable to maintain the biological and physiological functions continuing three dimensional spatial organizations for chondrocytes. As a scaffold, hydrogels alone is weak at endure complex loading within the body. In this study, we made cell hybrid scaffold constructs with poly (L-Lactic-co-${\varepsilon}$-Caprolactone) (PLCL) scaffold and hydrogels to make a three-dimensional composition of cells and extracellular matrix, which would be a mimic of a native cartilage. Using a particle leaching technique with NaCl, we fabricated a highly-elastic scaffold from PLCL with 85% porosity and $300-500{\mu}m$ pore size. A mixture of bovine chondrocytes and chitosan-alginate gel was seeded and compared with alginate as a control on the PLCL scaffold. The cell maturation, proliferation, extracellular matrix synthesis, glycosaminoglycans (sGAG) production and collagen type-II expressions were better in chondrocytes seeded in chitosan-alginate hydrogel than in alginate only. These results indicate that chondrocytes with chitosan-alginate gel on PLCL scaffolds provide an appropriate biomimetic environment for cell proliferation and matrix synthesis, which could successfully be used for cartilage repair and regeneration.

• Journal of Life Science
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• v.30 no.4
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• pp.402-409
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• 2020

Nervous necrosis virus (NNV) contains a bi-segmented viral genome, RNA1 (3.4 kb, RdRp), and RNA2 (1.4 kb, capsid protein) in a small particle (25 nm). Despite its extremely compact size, NNV has caused serious damage by infecting approximately 120 fish species worldwide since it was first reported in the late 1980s. In order to minimize the damage caused by NNV infection and develop effective vaccines, it is necessary to understand the intra cellular signaling system according to NNV infection. NNV infection induces cell cycle arrest at the G1 phase via the p53-dependent pathway to use the cellular system for its replication. Otherwise, host cells recognize NNV infection through the RIG-1-like receptor (RLR) signaling pathway to control the virus and infected cells, and then ISGs required for antiviral action are activated via the IFN signaling pathway. Moreover, apoptosis of infected cells is triggered by the unfolded protein response (UPR) through ER stress and mitochondria-mediated cell death. Cell signaling studies on the NNV infection mechanisms are still at an early stage and many pathways have yet to be identified. Understanding the various disease-specific cellular signaling systems associated with NNV infection is essential for rapid and accurate diagnosis and vaccine development.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.40 no.2
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• pp.145-156
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• 2020

The climate change occurring all over the world increases the risk, specially in urban area, Accordingly, rainwater pumping station expansion is required than before. In order to increase the efficiency of the rainwater pumping station, the analysis of flow characteristics in the pump sump is needed for vortex control. Many efforts have been made to illuminate the vortex behavior using PIV, but any reliable results have not been obtained yet, because of the limitations in image capturing and dependency of measured velocity values on the interrogation area and time interval used for velocity calculation. In this study, therefore, experiments were carried out to find out the limitation of PIV and estimate the validation of the velocity values associated with the analysis parameters such as interrogation area, time interval, grid size. For the experimental condition used in this study, the limitation of PIV and the effects of parameters on the velocity estimation are presented.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 1999.04a
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• pp.5-5
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• 1999

The Principal deficiency of the existing notion about the sintering-mixtures consists in the fact that almost no attention is focused on the Phenomenon of alloy formation during sintering, its connection with dimensional changes of powder bodies, and no correct ideas on the driving force for the sintering process in the stage of establishing chemical equilibrium in a system are available as well. Another disadvantage of the classical sintering theory is an erroneous conception on the dissolution mechanism of solid in liquid. The two-particle model widely used in the literature to describe the sintering phenomenon in solid state disregards the nature of the neighbouring surrounding particles, the presence of pores between them, and the rise of so called arch effect. In this presentation, new basic scientific principles of the driving forces for the sintering process of a two-component powder body, of a diffusion mechanism of the interaction between solid and liquid phases, of stresses and deformation arising in the diffusion zone have been developed. The major driving force for sintering the mixture from components capable of forming solid solutions and intermetallic compounds is attributed to the alloy formation rather than the reduction of the free surface area until the chemical equilibrium is achieved in a system. The lecture considers a multiparticle model of the mixed powder-body and the nature of its volume changes during solid-state and liquid-phase sintering. It explains the discovered S-and V-type concentration dependencies of the change in the compact volume during solid-state sintering. It is supposed in the literature that the dissolution of solid in liquid is realised due to the removal of atoms from the surface of the solid phase into the melt and then their diffusicn transfer from the solid-liquid interface into the bulk of liquid. It has been shown in our experimental studies that the mechanism of the interaction between two components, one of them being liquid, consist in diffusion of the solvent atoms from the liquid into the solid phase until the concentration of solid solutions or an intermetallic compound in the surface layer enables them to pass into the liquid by means of melting. The lecture discusses peculimities of liquid phase formation in systems with intermediate compounds and the role of the liquid phase in bringing about the exothermic effect. At the frist stage of liquid phase sintering the diffusion of atoms from the melt into the solid causes the powder body to grow. At the second stage the diminution of particles in size as a result of their dissolution in the liquid draws their centres closer to each other and makes the compact to shrink Analytical equations were derived to describe quantitatively the porosity and volume changes of compacts as a result of alloy formation during liquid phase sinteIing. Selection criteria for an additive, its concentration and the temperature regime of sintering to control the density the structure of sintered alloys are given.

• Applied Chemistry for Engineering
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• v.27 no.6
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• pp.612-619
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• 2016

In this research, an alumino-borosilicate foamed glass with sound absorption property was prepared using the waste borosilicate glass obtained from the recycling process of waste liquid crystal display (LCD) panel. A 100 g of pulverized waste borosilicate glass with the particle size of under 325 mesh, was mixed with 0.3 g (wt/wt) of graphite, each 1.5 g (wt/wt) of $Na_2CO_3$, $Na_2SO_4$ and $CaCO_3$ as a foaming agent, and 6.0 g (wt/wt) of $H_3BO_3$ and 3.0 g (wt/wt) of $Al_2O_3$ as a pore control agent. Following mixture was under the foaming process for 20 minutes at a foaming temperature of $950^{\circ}C$. The result yielded the foaming agent with 45% of the opened porosity and 0.5-0.7 of the sound absorbing coefficient. This alumino-borosilicate foamed glass with the sound absorption property showed excellent physical and mechanical properties such as density of $0.21g/cm^3$, bending strength of $55N/cm^2$ and compression strength of $298N/cm^2$ which can be ideally used as sound absorption materials with heat-resisting and chemical-resisting property.

• Polymer(Korea)
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• v.36 no.5
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• pp.586-592
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• 2012

Iron oxides ($Fe_3O_4$) are metabolically secreted after endocytosed by cells, indicating no cytotoxicity. Therefore, they are widely used as a contrast agent before photographing of magnetic resonance imaging. In this study, iron oxide nanoparticles are synthesized by the co-precipitation method and subsequently immobilized with a homing peptide (AP), which specifically interacts with interleukin-4 receptor located on the membrane of endothelial and bladder cancer cells. The size of AP-immobilized iron oxide particle is about 39 nm. Intracellular uptake of the AP-immobilized iron oxide nanoparticles was investigated using bladder cancer cells and fibroblasts as the control. As the result, the nanoparticles are specificially uptaken by bladder cancer cells. However, the nanoparticles are not specificially uptaken by fibroblast. It could be said that the AP-immobilized iron oxide nanoparticles have a potential to be used as a contrast agent for early diagnosis of cancer.